L. Watkins and S. Maier, GLIA: A novel drug discovery target for clinical pain, Nature Reviews Drug Discovery, vol.2, issue.12, pp.973-985, 2003.
DOI : 10.1038/nrd1251

L. Buda, C. Koblish, M. Tuthill, P. Dolle, R. Little et al., Antinociceptive activity of the selective iNOS inhibitor AR-C102222 in rodent models of inflammatory, neuropathic and post-operative pain, Eur J Pain, vol.10, pp.505-512, 2006.

S. Meller, P. Pechman, G. Gebhart, and T. Maves, Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat, Neuroscience, vol.50, issue.1, pp.7-10, 1992.
DOI : 10.1016/0306-4522(92)90377-E

A. Schmidtko, W. Gao, P. König, S. Heine, and R. Motterlini, cGMP Produced by NO-Sensitive Guanylyl Cyclase Essentially Contributes to Inflammatory and Neuropathic Pain by Using Targets Different from cGMP-Dependent Protein Kinase I, Journal of Neuroscience, vol.28, issue.34, pp.8568-8576, 2008.
DOI : 10.1523/JNEUROSCI.2128-08.2008

D. Alba, J. Clayton, N. Collins, S. Colthup, P. Chessell et al., GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain, Pain, vol.120, issue.1-2, pp.170-181, 2006.
DOI : 10.1016/j.pain.2005.10.028

A. Hervera, R. Negrete, S. Leánez, J. Martín-campos, and O. Pol, The Spinal Cord Expression of Neuronal and Inducible Nitric Oxide Synthases and Their Contribution in the Maintenance of Neuropathic Pain in Mice, PLoS ONE, vol.25, issue.12, p.14321, 2010.
DOI : 10.1371/journal.pone.0014321.g004

D. Levy and D. Zochodne, Local nitric oxide synthase activity in a model of neuropathic pain, European Journal of Neuroscience, vol.24, issue.Suppl. 2, pp.1846-1855, 1998.
DOI : 10.1046/j.1460-9568.1998.00186.x

K. Kuboyama, M. Tsuda, M. Tsutsui, Y. Toyohara, and H. Tozaki-saitoh, Reduced Spinal Microglial Activation and Neuropathic Pain after Nerve Injury in Mice Lacking all Three Nitric Oxide Synthases, Molecular Pain, vol.50, p.50, 2011.
DOI : 10.1002/(SICI)1098-1136(199711)21:3<285::AID-GLIA4>3.0.CO;2-4

A. Hervera, R. Negrete, S. Leánez, J. Martín-campos, and O. Pol, The Role of Nitric Oxide in the Local Antiallodynic and Antihyperalgesic Effects and Expression of ??-Opioid and Cannabinoid-2 Receptors during Neuropathic Pain in Mice, Journal of Pharmacology and Experimental Therapeutics, vol.334, issue.3, pp.887-896, 2010.
DOI : 10.1124/jpet.110.167585

A. Naik, S. Tandan, D. Kumar, and S. Dudhgaonkar, Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats, European Journal of Pharmacology, vol.530, issue.1-2, pp.59-69, 2006.
DOI : 10.1016/j.ejphar.2005.11.029

W. Fan, F. Huang, Z. Wu, X. Zhu, and D. Li, Carbon monoxide: A gas that modulates nociception, Journal of Neuroscience Research, vol.260, issue.6, pp.802-807, 2011.
DOI : 10.1002/jnr.22613

A. Rosa, J. Egea, S. Lorrio, A. Rojo, and A. Cuadrado, Nrf2-mediated haeme oxygenase-1 up-regulation induced by cobalt protoporphyrin has antinociceptive effects against inflammatory pain in the formalin test in mice, Pain, vol.137, issue.2, pp.332-339, 2008.
DOI : 10.1016/j.pain.2007.09.015

A. Steiner, L. Branco, F. Cunha, and S. Ferreira, Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity, British Journal of Pharmacology, vol.2, issue.Suppl 2, pp.1673-1682, 2000.
DOI : 10.1038/sj.bjp.0704014

X. Li and J. Clark, The Role of Heme Oxygenase in Neuropathic and Incisional Pain, Anesthesia & Analgesia, vol.90, issue.3, pp.677-682, 2000.
DOI : 10.1097/00000539-200003000-00031

X. Li and J. Clark, Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain, The Journal of Pain, vol.4, issue.2, pp.101-107, 2003.
DOI : 10.1054/jpai.2003.18

M. Alcaraz, A. Habib, M. Lebret, C. Créminon, and S. Lévy-toledano, Enhanced expression of haem oxygenase-1 by nitric oxide and antiinflammatory drugs in NIH 3T3 fibroblasts, British Journal of Pharmacology, vol.6, issue.1, pp.57-64, 2000.
DOI : 10.1038/sj.bjp.0703281

R. Foresti, J. Clark, C. Green, and R. Motterlini, Thiol Compounds Interact with Nitric Oxide in Regulating Heme Oxygenase-1 Induction in Endothelial Cells: INVOLVEMENT OF SUPEROXIDE AND PEROXYNITRITE ANIONS, Journal of Biological Chemistry, vol.272, issue.29, pp.18411-18417, 1997.
DOI : 10.1074/jbc.272.29.18411

Y. Kim, H. Bergonia, C. Müller, B. Pitt, and W. Watkins, Loss and degradation of enzyme-bound heme induced by cellular nitric oxide synthesis, J Biol Chem, vol.270, pp.5710-5713, 1995.

S. Lee, D. Park, H. Lee, J. Lee, and M. Choi, Functional interaction between nitric oxide-induced iron homeostasis and heme oxygenase-1 in immortalized and malignant oral keratinocytes, Cancer Letters, vol.249, issue.2, pp.283-293, 2007.
DOI : 10.1016/j.canlet.2006.09.012

J. Clark, P. Naughton, S. Shurey, C. Green, and T. Johnson, Cardioprotective Actions by a Water-Soluble Carbon Monoxide-Releasing Molecule, Circulation Research, vol.93, issue.2, pp.2-8, 2003.
DOI : 10.1161/01.RES.0000084381.86567.08

R. Motterlini, J. Clark, R. Foresti, P. Sarathchandra, and B. Mann, Carbon Monoxide-Releasing Molecules: Characterization of Biochemical and Vascular Activities, Circulation Research, vol.90, issue.2, pp.17-24, 2002.
DOI : 10.1161/hh0202.104530

R. Motterlini and L. Otterbein, The therapeutic potential of carbon monoxide, Nature Reviews Drug Discovery, vol.51, issue.9, pp.728-743, 2010.
DOI : 10.1038/nrd3228

P. Sawle, R. Foresti, B. Mann, T. Johnson, and C. Green, Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264, 2005.

M. Guillén, J. Megías, V. Clérigues, F. Gomar, and M. Alcaraz, The CO-releasing molecule CORM-2 is a novel regulator of the inflammatory process in osteoarthritic chondrocytes, Rheumatology, vol.47, issue.9, pp.1323-1328, 2008.
DOI : 10.1093/rheumatology/ken264

J. Mika, M. Osikowicz, E. Rojewska, M. Korostynski, and A. Wawrzczak-bargiela, Differential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain, European Journal of Pharmacology, vol.623, issue.1-3, pp.65-72, 2009.
DOI : 10.1016/j.ejphar.2009.09.030

C. Nascimento and L. Branco, Role of the peripheral heme oxygenase???carbon monoxide pathway on the nociceptive response of rats to the formalin test: Evidence for a cGMP signaling pathway, European Journal of Pharmacology, vol.556, issue.1-3, pp.55-61, 2007.
DOI : 10.1016/j.ejphar.2006.10.009

N. Maicas, M. Ferrándiz, I. Devesa, R. Motterlini, and M. Koenders, The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model, European Journal of Pharmacology, vol.634, issue.1-3, pp.184-191, 2010.
DOI : 10.1016/j.ejphar.2010.02.028

J. Megías, M. Guillén, V. Clérigues, A. Rojo, and A. Cuadrado, Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E2 production in osteoarthritic chondrocytes, Biochemical Pharmacology, vol.77, issue.12, pp.1806-1813, 2009.
DOI : 10.1016/j.bcp.2009.03.009

T. Gordh, H. Sharma, M. Azizi, P. Alm, and J. Westman, Spinal nerve lesion induces upregulation of constitutive isoform of heme oxygenase in the spinal cord, Amino Acids, vol.19, issue.1, pp.373-381, 2000.
DOI : 10.1007/s007260070068

L. Watkins, E. Milligan, and S. Maier, Glial activation: a driving force for pathological pain, Trends in Neurosciences, vol.24, issue.8, pp.450-455, 2001.
DOI : 10.1016/S0166-2236(00)01854-3

M. Bani-hani, D. Greenstein, B. Mann, C. Green, and R. Motterlini, A carbon monoxide-releasing molecule (CORM-3) attenuates lipopolysaccharideand interferon-gamma-induced inflammation in microglia, Pharmacol Rep, vol.58, pp.132-144, 2006.

W. Wilkinson and P. Kemp, The carbon monoxide donor, CORM-2, is an antagonist of ATP-gated, human P2X4 receptors, Purinergic Signalling, vol.284, issue.Pt 23, pp.57-64, 2011.
DOI : 10.1007/s11302-010-9213-8

M. Tsuda, Y. Shigemoto-mogami, S. Koizumi, A. Mizokoshi, and S. Kohsaka, P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury, Nature, vol.424, issue.6950, pp.778-783, 2003.
DOI : 10.1038/nature01786

G. Bennett and Y. Xie, A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man, Pain, vol.33, issue.1, pp.87-107, 1988.
DOI : 10.1016/0304-3959(88)90209-6

S. Chaplan, F. Bach, J. Pogrel, J. Chung, and T. Yaksh, Quantitative assessment of tactile allodynia in the rat paw, Journal of Neuroscience Methods, vol.53, issue.1, pp.55-63, 1994.
DOI : 10.1016/0165-0270(94)90144-9

K. Hargreaves, R. Dubner, F. Brown, C. Flores, and J. Joris, A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia, Pain, vol.32, issue.1, pp.77-88, 1988.
DOI : 10.1016/0304-3959(88)90026-7

I. Devesa, M. Ferrándiz, M. Terencio, L. Joosten, . Van-den et al., Influence of heme oxygenase 1 modulation on the progression of murine collagen-induced arthritis, Arthritis & Rheumatism, vol.94, issue.10, pp.3230-3238, 2005.
DOI : 10.1002/art.21356