N. G. Abraham, J. C. Nelson, T. Ahmed, G. Konwalinka, and R. D. Levere, Erythropoietin controls heme metabolic enzymes in normal human bone marrow culture, Exp Hematol, vol.17, pp.908-913, 1989.

Y. Akamatsu, M. Haga, S. Tyagi, K. Yamashita, A. V. Graca-souza et al., Heme oxygenase-1-derived carbon monoxide protects hearts from transplant-associated ischemia reperfusion injury, The FASEB Journal, vol.18, pp.771-772, 2004.
DOI : 10.1096/fj.03-0921fje

S. Al-assaf, S. Navaratnam, B. J. Parsons, and G. O. Phillips, Chain scission of hyaluronan by carbonate and dichloride radical anions: potential reactive oxidative species in inflammation? Free Radical Biology & Medicine, pp.2018-2027, 2006.

A. Ghouleh, I. Khoo, N. K. Knaus, U. G. Griendling, K. K. Touyz et al., Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling, Free Radical Biology and Medicine, vol.51, issue.7, pp.1271-1288, 2011.
DOI : 10.1016/j.freeradbiomed.2011.06.011

M. Althaus, M. Fronius, Y. Buchackert, I. Vadasz, W. G. Clauss et al., Carbon Monoxide Rapidly Impairs Alveolar Fluid Clearance by Inhibiting Epithelial Sodium Channels, American Journal of Respiratory Cell and Molecular Biology, vol.41, issue.6, pp.639-650, 2009.
DOI : 10.1165/rcmb.2008-0458OC

F. Amersi, X. D. Shen, D. Anselmo, J. Melinek, S. Iyer et al., Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway, Hepatology, vol.278, issue.4, pp.815-823, 2002.
DOI : 10.1053/jhep.2002.32467

T. Ashino, R. Yamanaka, M. Yamamoto, H. Shimokawa, K. Sekikawa et al., Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages, Molecular Immunology, vol.45, issue.7, pp.2106-2115, 2008.
DOI : 10.1016/j.molimm.2007.10.011

O. Augusto, M. G. Bonini, A. M. Amanso, E. Linares, C. C. Santos et al., Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology, Free Radical Biology and Medicine, vol.32, issue.9, pp.841-859, 2002.
DOI : 10.1016/S0891-5849(02)00786-4

A. Bagul, S. A. Hosgood, M. Kaushik, and M. L. Nicholson, Carbon Monoxide Protects Against Ischemia-Reperfusion Injury in an Experimental Model of Controlled Nonheartbeating Donor Kidney, Transplantation, vol.85, issue.4, pp.576-581, 2008.
DOI : 10.1097/TP.0b013e318160516a

H. Heme and . Oxygenase, and ferritin: how the vascular endothelium survives (and dies) in an iron-rich environment, Antioxid Redox Signal, vol.9, pp.2119-2137

I. Barbagallo, G. Marrazzo, A. Frigiola, A. Zappala, and G. L. Volti, Role of Carbon Monoxide in Vascular Diseases, Current Pharmaceutical Biotechnology, vol.13, issue.6, 2012.
DOI : 10.2174/138920112800399086

I. Bauer and B. H. Pannen, Bench-to-bedside review: Carbon monoxide ??? from mitochondrial poisoning to therapeutic use, Critical Care, vol.13, issue.4, p.220, 2009.
DOI : 10.1186/cc7887

M. Bauer and I. Bauer, Heme Oxygenase-1: Redox Regulation and Role in the Hepatic Response to Oxidative Stress, Antioxidants & Redox Signaling, vol.4, issue.5, pp.749-758, 2002.
DOI : 10.1089/152308602760598891

M. Benderitter, F. Hadj-saad, M. Lhuissier, V. Maupoil, J. C. Guilland et al., Effects of exhaustive exercise and vitamin b6 deficiency on free radical oxidative process in male trained rats, Free Radical Biology and Medicine, vol.21, issue.4, pp.541-549, 1996.
DOI : 10.1016/0891-5849(96)00047-0

P. O. Berberat, M. Katori, E. Kaczmarek, D. Anselmo, C. Lassman et al., Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury, FASEB J, vol.17, pp.1724-1726, 2003.

C. Bergstraesser, S. Hoeger, H. Song, L. Ermantraut, M. Hottenrot et al., Inhibition of VCAM-1 expression in endothelial cells by CORM-3: The role of the ubiquitin???proteasome system, p38, and mitochondrial respiration, Free Radical Biology and Medicine, vol.52, issue.4, pp.794-802, 2012.
DOI : 10.1016/j.freeradbiomed.2011.11.035

F. Bernuzzi, S. Recalcati, A. Alberghini, and G. Cairo, Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2 cardiomyocytes: Role for heme oxygenase-1 down-modulation, Chemico-Biological Interactions, vol.177, issue.1, pp.12-20, 2009.
DOI : 10.1016/j.cbi.2008.09.012

P. Bhargava and C. H. Lee, Role and function of macrophages in the metabolic syndrome, Biochemical Journal, vol.2010, issue.2, pp.253-262, 2012.
DOI : 10.1016/j.ijcard.2004.01.034

M. Bilban, F. H. Bach, S. L. Otterbein, E. Ifedigbo, J. C. Avila et al., Carbon Monoxide Orchestrates a Protective Response through PPAR??, Immunity, vol.24, issue.5, pp.601-610, 2006.
DOI : 10.1016/j.immuni.2006.03.012

M. Bilban, A. Haschemi, B. Wegiel, B. Y. Chin, O. Wagner et al., Heme oxygenase and carbon monoxide initiate homeostatic signaling, Journal of Molecular Medicine, vol.20, issue.5, pp.267-279, 2008.
DOI : 10.1007/s00109-007-0276-0

S. Brouard, L. E. Otterbein, J. Anrather, E. Tobiasch, F. H. Bach et al., Carbon Monoxide Generated by Heme Oxygenase 1 Suppresses Endothelial Cell Apoptosis, The Journal of Experimental Medicine, vol.278, issue.7, pp.1015-1026, 2000.
DOI : 10.1016/S1074-7613(00)80449-5

A. Burgess, L. Vanella, L. Bellner, M. L. Schwartzman, and N. G. Abraham, Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications, Prostaglandins & Other Lipid Mediators, vol.97, issue.1-2, pp.1-16, 2012.
DOI : 10.1016/j.prostaglandins.2011.10.002

G. Cairo, S. Recalcati, A. Mantovani, and M. Locati, Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype, Trends in Immunology, vol.32, issue.6, pp.241-247, 2011.
DOI : 10.1016/j.it.2011.03.007

J. Cao, K. Sodhi, N. Puri, S. R. Monu, R. Rezzani et al., High fat diet enhances cardiac abnormalities in SHR rats: Protective role of heme oxygenase-adiponectin axis, Diabetology & Metabolic Syndrome, vol.3, issue.1, p.37, 2011.
DOI : 10.1016/S0014-5793(98)01705-0

K. H. Chan, M. K. Ng, and R. Stocker, Haem oxygenase-1 and cardiovascular disease: mechanisms and therapeutic potential, Clinical Science, vol.344, issue.12, pp.493-504, 2011.
DOI : 10.1016/j.jacc.2005.05.079

K. Chandran, J. Mccracken, F. C. Peterson, W. E. Antholine, B. F. Volkman et al., Oxidation of Histidine Residues in Copper???Zinc Superoxide Dismutase by Bicarbonate-Stimulated Peroxidase and Thiol Oxidase Activities: Pulse EPR and NMR Studies, Biochemistry, vol.49, issue.50, pp.10616-10622, 2010.
DOI : 10.1021/bi1010305

P. K. Chatterjee, Water-soluble carbon monoxide-releasing molecules: helping to elucidate the vascular activity of the ???silent killer???, British Journal of Pharmacology, vol.259, issue.3, pp.391-393, 2004.
DOI : 10.1038/sj.bjp.0705826

B. Chen, L. Guo, C. Fan, S. Bolisetty, R. Joseph et al., Carbon Monoxide Rescues Heme Oxygenase-1-Deficient Mice from Arterial Thrombosis in Allogeneic Aortic Transplantation, The American Journal of Pathology, vol.175, issue.1, pp.422-429, 2009.
DOI : 10.2353/ajpath.2009.081033

S. N. Chen and M. Z. Hoffman, Rate Constants for the Reaction of the Carbonate Radical with Compounds of Biochemical Interest in Neutral Aqueous Solution, Radiation Research, vol.56, issue.1, pp.40-47, 1973.
DOI : 10.2307/3573789

S. Chlopicki, R. Olszanecki, E. Marcinkiewicz, M. Lomnicka, and R. Motterlini, Carbon monoxide released by CORM-3 inhibits human platelets by a mechanism independent of soluble guanylate cyclase, Cardiovascular Research, vol.71, issue.2, pp.393-401, 2006.
DOI : 10.1016/j.cardiores.2006.03.011

B. M. Choi, H. O. Pae, Y. M. Kim, and H. T. Chung, Nitric oxide-mediated cytoprotection of hepatocytes from glucose deprivation-induced cytotoxicity: Involvement of heme oxygenase-1, Hepatology, vol.7, issue.4, 2003.
DOI : 10.1053/jhep.2003.50114

S. W. Chung, X. Liu, A. A. Macias, R. M. Baron, and M. A. Perrella, Heme oxygenase-1???derived carbon monoxide enhances the host defense response to microbial sepsis in mice, Journal of Clinical Investigation, vol.118, issue.1, pp.239-247, 2008.
DOI : 10.1172/JCI32730DS1

J. E. Clark, P. Naughton, S. Shurey, C. J. Green, T. R. Johnson et al., Cardioprotective Actions by a Water-Soluble Carbon Monoxide-Releasing Molecule, Circulation Research, vol.93, issue.2, pp.2-8, 2003.
DOI : 10.1161/01.RES.0000084381.86567.08

C. E. Cooper and G. C. Brown, The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance, Journal of Bioenergetics and Biomembranes, vol.21, issue.Suppl, pp.533-539, 2008.
DOI : 10.1007/s10863-008-9166-6

L. R. Coulthard, D. E. White, D. L. Jones, M. F. Mcdermott, and S. A. Burchill, (MAPK): stress responses from molecular mechanisms to therapeutics, Trends Mol Med, vol.15, pp.38-369, 2009.

F. J. Cronje, M. S. Carraway, J. J. Freiberger, H. B. Suliman, and C. A. Piantadosi, CARBON MONOXIDE ACTUATES O2-LIMITED HEME DEGRADATION IN THE RAT BRAIN, Free Radical Biology and Medicine, vol.37, issue.11, pp.1802-1812, 2004.
DOI : 10.1016/j.freeradbiomed.2004.08.022

M. L. Dallas, J. P. Boyle, C. J. Milligan, R. Sayer, T. L. Kerrigan et al., Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2, FASEB J, vol.1, issue.25, pp.1519-1530, 2011.

Y. Dohi, T. Ikura, Y. Hoshikawa, Y. Katoh, K. Ota et al., Bach1 inhibits oxidative stress???induced cellular senescence by impeding p53 function on chromatin, Nature Structural & Molecular Biology, vol.1, issue.12, pp.1246-1254, 2008.
DOI : 10.1093/emboj/20.6.1331

D. L. Dong, Y. Zhang, D. H. Lin, J. Chen, S. Patschan et al., Carbon Monoxide Stimulates the Ca2+ Activated Big Conductance K Channels in Cultured Human Endothelial Cells, Carbon monoxide stimulates the Ca2(+)-activated big conductance k channels in cultured human endothelial cells, pp.643-651, 2007.
DOI : 10.1161/HYPERTENSIONAHA.107.096057

G. Dordelmann, H. Pfeiffer, A. Birkner, and U. Schatzschneider, Silicium Dioxide Nanoparticles As Carriers for Photoactivatable CO-Releasing Molecules (PhotoCORMs), Inorganic Chemistry, vol.50, issue.10, pp.4362-4367, 2011.
DOI : 10.1021/ic1024197

W. Durante, Targeting Heme Oxygenase-1 in Vascular Disease, Current Drug Targets, vol.11, issue.12, pp.1504-1516, 2010.
DOI : 10.2174/1389450111009011504

W. Durante, Protective role of heme oxygenase-1 against inflammation in atherosclerosis, Frontiers in Bioscience, vol.16, issue.1, pp.2372-2388, 2012.
DOI : 10.2741/3860

A. Ecarnot-laubriet, M. Assem, F. Poirson-bichat, M. Moisant, C. Bernard et al., Stage-dependent activation of cell cycle and apoptosis mechanisms in the right ventricle by pressure overload, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1586, issue.3, pp.233-242, 2002.
DOI : 10.1016/S0925-4439(01)00101-6

A. Ecarnot-laubriet, K. De-luca, D. Vandroux, M. Moisant, C. Bernard et al., Downregulation and Nuclear Relocation of MLP During the Progression of Right Ventricular Hypertrophy Induced by Chronic Pressure Overload, Journal of Molecular and Cellular Cardiology, vol.32, issue.12, pp.2385-2395, 2000.
DOI : 10.1006/jmcc.2000.1269

M. Fontenay, S. Cathelin, M. Amiot, E. Gyan, and E. Solary, Mitochondria in hematopoiesis and hematological diseases, Oncogene, vol.72, issue.34, pp.4757-4767, 2006.
DOI : 10.1101/gad.1045603

R. Foresti and R. Motterlini, Interaction of Carbon Monoxide with Transition Metals: Evolutionary Insights into Drug Target Discovery, Current Drug Targets, vol.11, issue.12, pp.1595-1604, 2010.
DOI : 10.2174/1389450111009011595

L. E. Fredenburgh, M. A. Perrella, and S. A. Mitsialis, The Role of Heme Oxygenase-1 in Pulmonary Disease, American Journal of Respiratory Cell and Molecular Biology, vol.36, issue.2, pp.158-165, 2007.
DOI : 10.1165/rcmb.2006-0331TR

T. Fujita, K. Toda, A. Karimova, S. F. Yan, Y. Naka et al., Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis, Nature Medicine, vol.7, issue.5, pp.598-604, 2001.
DOI : 10.1038/87929

S. Ghibu, S. Delemasure, C. Richard, J. C. Guilland, L. Martin et al., General oxidative stress during doxorubicin-induced cardiotoxicity in rats: Absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid, Biochimie, vol.94, issue.4, pp.932-939, 2012.
DOI : 10.1016/j.biochi.2011.02.015

URL : https://hal.archives-ouvertes.fr/hal-00828304

S. Ghibu, B. Lauzier, S. Delemasure, S. Amoureux, P. Sicard et al., Antioxidant properties of alpha-lipoic acid: effects on red blood membrane permeability and adaptation of isolated rat heart to reversible ischemia, Molecular and Cellular Biochemistry, vol.169, issue.1-2, pp.141-148, 2009.
DOI : 10.1007/s11010-008-9916-0

M. A. Gonzalez, M. A. Yim, S. Cheng, A. Moyes, A. J. Hobbs et al., Manganese Carbonyls Bearing Tripodal Polypyridine Ligands as Photoactive Carbon Monoxide-Releasing Molecules, Inorganic Chemistry, vol.51, issue.1, pp.601-608, 2012.
DOI : 10.1021/ic2021287

A. Grochot-przeczek, J. Dulak, and A. Jozkowicz, Heme oxygenase-1 in neovascularisation: A diabetic perspective, Thrombosis and Haemostasis, vol.104, issue.3, pp.424-431, 2010.
DOI : 10.1160/TH09-12-0825

B. Halliwell, Free Radicals in, Biology and Medicine, 2007.

B. Halliwell, Oxidative stress and cancer: have we moved forward?, Biochemical Journal, vol.401, issue.1, pp.1-11, 2007.
DOI : 10.1042/BJ20061131

J. L. Hart, Role of sulfur-containing gaseous substances in the cardiovascular system, Frontiers in Bioscience, vol.3, issue.2, pp.736-749, 2011.
DOI : 10.2741/e282

A. Haschemi, B. Y. Chin, M. Jeitler, H. Esterbauer, O. Wagner et al., Carbon Monoxide Induced PPAR?? SUMOylation and UCP2 Block Inflammatory Gene Expression in Macrophages, PLoS ONE, vol.2, issue.10, p.26376, 2011.
DOI : 10.1371/journal.pone.0026376.g005

H. Heli, S. Mirtorabi, and K. Karimian, Advances in iron chelation: an update, Expert Opinion on Therapeutic Patents, vol.1, issue.6, pp.819-856, 2011.
DOI : 10.1080/07391102.2009.10507319

T. D. Hock, K. Liby, M. M. Wright, S. Mcconnell, M. Schorpp-kistner et al., JunB and JunD Regulate Human Heme Oxygenase-1 Gene Expression in Renal Epithelial Cells, Journal of Biological Chemistry, vol.282, issue.9, pp.6875-6886, 2007.
DOI : 10.1074/jbc.M608456200

A. Hoetzel, T. Dolinay, R. Schmidt, A. M. Choi, and S. W. Ryter, Carbon Monoxide in Sepsis, Antioxidants & Redox Signaling, vol.9, issue.11, pp.2013-2026, 2007.
DOI : 10.1089/ars.2007.1762

A. Hoffman, S. Goldstein, A. Samuni, J. B. Borman, and H. Schwalb, Effect of nitric oxide and nitroxide SOD-mimic on the recovery of isolated rat heart following ischemia and reperfusion, Biochemical Pharmacology, vol.66, issue.7, pp.1279-1286, 2003.
DOI : 10.1016/S0006-2952(03)00441-6

I. Horvath and P. J. Barnes, Exhaled monoxides in asymptomatic atopic subjects, Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy, vol.12, issue.1, pp.1276-1280, 1999.
DOI : 10.1034/j.1399-3003.1999.13b14.x

P. A. Hosick and D. E. Stec, Heme oxygenase, a novel target for the treatment of hypertension and obesity?, AJP: Regulatory, Integrative and Comparative Physiology, vol.302, issue.2, pp.207-214, 2012.
DOI : 10.1152/ajpregu.00517.2011

M. Hultqvist, L. M. Olsson, K. A. Gelderman, and R. Holmdahl, The protective role of ROS in autoimmune disease, Trends in Immunology, vol.30, issue.5, pp.201-208, 2009.
DOI : 10.1016/j.it.2009.03.004

B. M. Hybertson, B. Gao, S. K. Bose, and J. M. Mccord, Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation, Molecular Aspects of Medicine, vol.32, issue.4-6, pp.234-246, 2011.
DOI : 10.1016/j.mam.2011.10.006

K. Igarashi and J. Sun, The Heme-Bach1 Pathway in the Regulation of Oxidative Stress Response and Erythroid Differentiation, Antioxidants & Redox Signaling, vol.8, issue.1-2, pp.107-118, 2006.
DOI : 10.1089/ars.2006.8.107

S. Ikehara, The Future of Stem Cell Transplantation in Autoimmune Disease, Clinical Reviews in Allergy & Immunology, vol.306, issue.2-3, pp.292-297, 2010.
DOI : 10.1007/s12016-009-8159-5

S. Immenschuh, E. Baumgart-vogt, and S. Mueller, Heme Oxygenase-1 and Iron in Liver Inflammation: A Complex Alliance, Current Drug Targets, vol.11, issue.12, pp.1541-1550, 2010.
DOI : 10.2174/1389450111009011541

S. Inoue, M. Suzuki, Y. Nagashima, S. Suzuki, T. Hashiba et al., Transfer of Heme Oxygenase 1 cDNA by a Replication-Deficient Adenovirus Enhances Interleukin 10 Production from Alveolar Macrophages That Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice, Human Gene Therapy, vol.12, issue.8, pp.967-979, 2001.
DOI : 10.1089/104303401750195926

J. H. Jang, T. J. Lee, E. S. Yang, S. Min-do, Y. H. Kim et al., Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1, Experimental Cell Research, vol.316, issue.13, pp.2194-2203, 2010.
DOI : 10.1016/j.yexcr.2010.04.028

D. Jay, H. Hitomi, and K. K. Griendling, Oxidative stress and diabetic cardiovascular complications, Free Radical Biology and Medicine, vol.40, issue.2, pp.183-192, 2006.
DOI : 10.1016/j.freeradbiomed.2005.06.018

G. S. Jeong, G. S. Oh, H. O. Pae, S. O. Jeong, Y. C. Kim et al., Comparative effects of curcuminoids on endothelial heme oxygenase-1 expression: ortho-methoxy groups are essential to enhance heme oxygenase activity and protection, Experimental & Molecular Medicine, vol.38, issue.4, pp.393-400, 2006.
DOI : 10.1038/emm.2006.46

T. Kaizu, A. Ikeda, A. Nakao, A. Tsung, H. Toyokawa et al., Protection of transplant-induced hepatic ischemia/reperfusion injury with carbon monoxide via MEK/ERK1/2 pathway downregulation, AJP: Gastrointestinal and Liver Physiology, vol.294, issue.1, pp.236-244, 2008.
DOI : 10.1152/ajpgi.00144.2007

M. Kajimura, R. Fukuda, R. M. Bateman, T. Yamamoto, and M. Suematsu, S Gas Biology, Antioxidants & Redox Signaling, vol.13, issue.2, pp.157-192, 2010.
DOI : 10.1089/ars.2009.2657

M. Kajimura, N. Goda, and M. Suematsu, Organ Design for Generation and Reception of CO: Lessons from the Liver, Antioxidants & Redox Signaling, vol.4, issue.4, pp.633-637, 2002.
DOI : 10.1089/15230860260220139

E. Kansanen, H. K. Jyrkkanen, and A. L. Levonen, Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids, Free Radical Biology and Medicine, vol.52, issue.6, pp.973-982, 2012.
DOI : 10.1016/j.freeradbiomed.2011.11.038

A. Kanu and C. W. Leffler, Carbon monoxide and Ca2+-activated K+ channels in cerebral arteriolar responses to glutamate and hypoxia in newborn pigs, AJP: Heart and Circulatory Physiology, vol.293, issue.5, pp.3193-3200, 2007.
DOI : 10.1152/ajpheart.00274.2007

J. W. Kaspar and A. K. Jaiswal, Antioxidant-induced Phosphorylation of Tyrosine 486 Leads to Rapid Nuclear Export of Bach1 That Allows Nrf2 to Bind to the Antioxidant Response Element and Activate Defensive Gene Expression, Journal of Biological Chemistry, vol.285, issue.1, pp.153-162, 2010.
DOI : 10.1074/jbc.M109.040022

A. Kawamoto and T. Asahara, Role of progenitor endothelial cells in cardiovascular disease and upcoming therapies, Catheterization and Cardiovascular Interventions, vol.55, issue.4, pp.477-484, 2007.
DOI : 10.1002/ccd.21292

K. Kemp, R. Morse, K. Sanders, J. Hows, and C. Donaldson, Alkylating chemotherapeutic agents cyclophosphamide and melphalan cause functional injury to human bone marrow-derived mesenchymal stem cells, Annals of Hematology, vol.32, issue.5, pp.777-789, 2011.
DOI : 10.1007/s00277-010-1141-8

URL : https://hal.archives-ouvertes.fr/hal-00615417

E. C. Kennett and M. J. Davies, Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation, Free Radical Biology and Medicine, vol.47, issue.4, pp.389-400, 2009.
DOI : 10.1016/j.freeradbiomed.2009.05.002

A. A. Khan and J. G. Quigley, Control of intracellular heme levels: Heme transporters and heme oxygenases, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1813, issue.5, pp.668-682, 2011.
DOI : 10.1016/j.bbamcr.2011.01.008

N. K. Khoo and B. A. Freeman, Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment, Current Opinion in Pharmacology, vol.10, issue.2, pp.179-184, 2010.
DOI : 10.1016/j.coph.2009.11.003

N. K. Khoo, V. Rudolph, M. P. Cole, F. Golin-bisello, F. J. Schopfer et al., Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids, Free Radical Biology and Medicine, vol.48, issue.2, pp.230-239, 2010.
DOI : 10.1016/j.freeradbiomed.2009.10.046

H. P. Kim, S. W. Ryter, and A. M. Choi, CO AS A CELLULAR SIGNALING MOLECULE, Annual Review of Pharmacology and Toxicology, vol.46, issue.1, pp.411-449, 2006.
DOI : 10.1146/annurev.pharmtox.46.120604.141053

H. P. Kim, X. Wang, A. Nakao, S. I. Kim, N. Murase et al., Caveolin-1 expression by means of p38?? mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide, Proceedings of the National Academy of Sciences, vol.102, issue.32, pp.11319-11324, 2005.
DOI : 10.1073/pnas.0501345102

Y. M. Kim, H. O. Pae, J. E. Park, Y. C. Lee, J. M. Woo et al., Heme Oxygenase in the Regulation of Vascular Biology: From Molecular Mechanisms to Therapeutic Opportunities, Antioxidants & Redox Signaling, vol.14, issue.1, pp.137-167, 2011.
DOI : 10.1089/ars.2010.3153

V. Koliaraki and G. Kollias, A New Role for Myeloid HO-1 in the Innate to Adaptive Crosstalk and Immune Homeostasis, Adv Exp Med Biol, vol.780, pp.101-111, 2011.
DOI : 10.1007/978-1-4419-5632-3_9

C. Korandji, M. Zeller, J. C. Guilland, B. Collin, B. Lauzier et al., Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: A model related to metabolic syndrome, Atherosclerosis, vol.214, issue.2, pp.310-315, 2011.
DOI : 10.1016/j.atherosclerosis.2010.11.014

C. Korandji, M. Zeller, J. C. Guilland, C. Vergely, P. Sicard et al., Asymmetric dimethylarginine (ADMA) and hyperhomocysteinemia in patients with acute myocardial infarction, Clinical Biochemistry, vol.40, issue.1-2, pp.66-72, 2007.
DOI : 10.1016/j.clinbiochem.2006.08.004

P. Krause, E. Watzig, H. Acil, S. Konig, K. Unthan-fechner et al., Role of carbon monoxide and nitric oxide in adult rat hepatocytes proliferating in vitro: Effects of CAS 1609, Nitric Oxide, vol.23, issue.3, pp.220-226, 2010.
DOI : 10.1016/j.niox.2010.06.007

A. L. Kruger, S. J. Peterson, M. L. Schwartzman, H. Fusco, J. A. Mcclung et al., Up-Regulation of Heme Oxygenase Provides Vascular Protection in an Animal Model of Diabetes through Its Antioxidant and Antiapoptotic Effects, Journal of Pharmacology and Experimental Therapeutics, vol.319, issue.3, pp.1144-1152, 2006.
DOI : 10.1124/jpet.106.107482

J. M. Kyriakis and J. Avruch, Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation, Physiol Rev, vol.81, pp.807-869, 2001.

B. D. Lamon, F. F. Zhang, N. Puri, S. V. Brodsky, M. S. Goligorsky et al., Dual Pathways of Carbon Monoxide-Mediated Vasoregulation: Modulation by Redox Mechanisms, Circulation Research, vol.105, issue.8, pp.775-783, 2009.
DOI : 10.1161/CIRCRESAHA.109.197434

B. Lauzier, S. Delemasure, R. Debin, B. Collin, P. Sicard et al., Beneficial Effects of Myocardial Postconditioning are Associated With Reduced Oxidative Stress in a Senescent Mouse Model, Transplantation, vol.85, issue.12, pp.1802-1808, 2008.
DOI : 10.1097/TP.0b013e3181775367

B. Lauzier, S. Delemasure, M. Pesant, B. Collin, L. Duvillard et al., A Cholesterol-Rich Diet Improves Resistance to Ischemic Insult in Mouse Hearts but Suppresses the Beneficial Effect of Post-Conditioning, The Journal of Heart and Lung Transplantation, vol.28, issue.8, pp.821-826, 2009.
DOI : 10.1016/j.healun.2009.04.030

B. Lauzier, P. Sicard, O. Bouchot, S. Delemasure, F. Menetrier et al., After Four Hours of Cold Ischemia and Cardioplegic Protocol, the Heart Can Still Be Rescued With Postconditioning, Transplantation, vol.84, issue.11, pp.1474-1482, 2007.
DOI : 10.1097/01.tp.0000288637.18796.0e

B. Lauzier, P. Sicard, O. Bouchot, S. Delemasure, D. Moreau et al., A peroxynitrite decomposition catalyst: FeTPPS confers cardioprotection during reperfusion after cardioplegic arrest in a working isolated rat heart model, Fundamental & Clinical Pharmacology, vol.230, issue.2, pp.173-180, 2007.
DOI : 10.1124/jpet.102.036871

S. Lecour, V. Maupoil, O. Siri, A. Tabard, and L. Rochette, Electron Spin Resonance Detection of Nitric Oxide Generation in Major Organs from LPS-Treated Rats, Journal of Cardiovascular Pharmacology, vol.33, issue.1, pp.78-85, 1999.
DOI : 10.1097/00005344-199901000-00012

S. Lecour, V. Maupoil, M. Zeller, A. Laubriet, F. Briot et al., Levels of Nitric Oxide in the Heart After Experimental Myocardial Ischemia, Journal of Cardiovascular Pharmacology, vol.37, issue.1, pp.55-63, 2001.
DOI : 10.1097/00005344-200101000-00007

B. S. Lee, J. Heo, Y. M. Kim, S. M. Shim, H. O. Pae et al., Carbon monoxide mediates heme oxygenase 1 induction via Nrf2 activation in hepatoma cells, Biochemical and Biophysical Research Communications, vol.343, issue.3, pp.965-972, 2006.
DOI : 10.1016/j.bbrc.2006.03.058

S. J. Lee, S. W. Ryter, J. Xu, K. Nakahira, H. P. Kim et al., Carbon Monoxide Activates Autophagy via Mitochondrial Reactive Oxygen Species Formation, American Journal of Respiratory Cell and Molecular Biology, vol.45, issue.4, 2011.
DOI : 10.1165/rcmb.2010-0352OC

C. W. Leffler, H. Parfenova, and J. H. Jaggar, Carbon monoxide as an endogenous vascular modulator, AJP: Heart and Circulatory Physiology, vol.301, issue.1, pp.1-11, 2011.
DOI : 10.1152/ajpheart.00230.2011

M. Li and N. K. Fukagawa, Age-Related Changes in Redox Signaling and VSMC Function, Antioxidants & Redox Signaling, vol.12, issue.5, pp.641-655, 2010.
DOI : 10.1089/ars.2009.2854

Q. Li, Y. Guo, Q. Ou, C. Cui, W. J. Wu et al., Gene Transfer of Inducible Nitric Oxide Synthase Affords Cardioprotection by Upregulating Heme Oxygenase-1 Via a Nuclear Factor-??B-Dependent Pathway, Circulation, vol.120, issue.13, pp.1222-1230, 2009.
DOI : 10.1161/CIRCULATIONAHA.108.778688

Y. Li, J. Qi, K. Liu, B. Li, H. Wang et al., Peroxynitrite-induced nitration of cyclooxygenase- 2 and inducible nitric oxide synthase promotes their binding in diabetic angiopathy, Mol Med, vol.16, pp.335-342, 2010.

I. Lim, S. J. Gibbons, G. L. Lyford, S. M. Miller, P. R. Strege et al., Carbon monoxide activates human intestinal smooth muscle L-type Ca2+ channels through a nitric oxide-dependent mechanism, AJP: Gastrointestinal and Liver Physiology, vol.288, issue.1, pp.7-14, 2005.
DOI : 10.1152/ajpgi.00205.2004

H. H. Lin, Y. H. Chen, S. F. Yet, and L. Y. Chau, After vascular injury, heme oxygenase-1/carbon monoxide enhances re-endothelialization via promoting mobilization of circulating endothelial progenitor cells, Journal of Thrombosis and Haemostasis, vol.70, issue.8, pp.1401-1408, 2009.
DOI : 10.1111/j.1538-7836.2009.03478.x

X. M. Liu, K. J. Peyton, A. R. Shebib, H. Wang, and W. Durante, Compound C stimulates heme oxygenase-1 gene expression via the Nrf2-ARE pathway to preserve human endothelial cell survival, Biochemical Pharmacology, vol.82, issue.4, pp.371-379, 2011.
DOI : 10.1016/j.bcp.2011.05.016

L. Iacono, L. Boczkowski, J. Zini, R. Salouage, I. Berdeaux et al., A carbon monoxide-releasing molecule (CORM-3) uncouples mitochondrial respiration and modulates the production of reactive oxygen species, Free Radical Biology and Medicine, vol.50, issue.11, pp.1556-1564, 2011.
DOI : 10.1016/j.freeradbiomed.2011.02.033

URL : https://hal.archives-ouvertes.fr/inserm-00597718

P. A. Lochhead, R. Gilley, and S. J. Cook, ERK5 and its role in tumour development: Figure 1, Biochemical Society Transactions, vol.16, issue.1, pp.251-256, 2012.
DOI : 10.1016/j.ccr.2010.08.008

S. C. Lu, Regulation of glutathione synthesis, Molecular Aspects of Medicine, vol.30, issue.1-2, pp.42-59, 2009.
DOI : 10.1016/j.mam.2008.05.005

S. P. Lu, L. Feng, M. H. Huang, H. L. Huang, Y. C. Tsou et al., Reactive oxygen species promote raft formation in T lymphocytes???, Free Radical Biology and Medicine, vol.42, issue.7, pp.936-944, 2007.
DOI : 10.1016/j.freeradbiomed.2006.11.027

A. K. Macleod, M. Mcmahon, S. M. Plummer, L. G. Higgins, T. M. Penning et al., Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds, Carcinogenesis, vol.30, issue.9, pp.1571-1580, 2009.
DOI : 10.1093/carcin/bgp176

N. Maicas, M. L. Ferrandiz, I. Devesa, R. Motterlini, M. I. Koenders et al., The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model, European Journal of Pharmacology, vol.634, issue.1-3, pp.184-191, 2010.
DOI : 10.1016/j.ejphar.2010.02.028

B. E. Mann and R. Motterlini, CO and NO in medicine, Chemical Communications, vol.20, issue.41, pp.4197-4208, 2007.
DOI : 10.1039/b704832g

R. Meli, T. Nauser, P. Latal, and W. H. Koppenol, Reaction of peroxynitrite with carbon dioxide: intermediates and determination of the yield of CO3 ?????? and NO2 ???, JBIC Journal of Biological Inorganic Chemistry, vol.7, issue.1-2, pp.31-36, 2002.
DOI : 10.1007/s007750100262

K. J. Min, J. T. Lee, E. H. Joe, and T. K. Kwon, An I??B?? phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)???Nrf2???ARE signaling and ROS???PI3K/Akt signaling in an NF-??B-independent mechanism, Cellular Signalling, vol.23, issue.9, pp.1505-1513, 2011.
DOI : 10.1016/j.cellsig.2011.05.013

T. Miyazaki, Y. Kirino, M. Takeno, S. Samukawa, M. Hama et al., Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1, Cancer Science, vol.278, issue.6, pp.1409-1416, 2010.
DOI : 10.1111/j.1349-7006.2010.01550.x

D. Morse, L. Lin, A. M. Choi, and S. W. Ryter, Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease, Free Radical Biology and Medicine, vol.47, issue.1, pp.1-12, 2009.
DOI : 10.1016/j.freeradbiomed.2009.04.007

R. Motterlini, Carbon monoxide-releasing molecules (CO-RMs): vasodilatory, anti-ischaemic and anti-inflammatory activities: Figure 1, Biochemical Society Transactions, vol.35, issue.5, pp.1142-1146, 2007.
DOI : 10.1042/BST0351142

R. Motterlini, B. E. Mann, T. R. Johnson, J. E. Clark, R. Foresti et al., Bioactivity and Pharmacological Actions of Carbon Monoxide-Releasing Molecules, Current Pharmaceutical Design, vol.9, issue.30, pp.2525-2539, 2003.
DOI : 10.2174/1381612033453785

R. Motterlini and L. E. Otterbein, The therapeutic potential of carbon monoxide, Nature Reviews Drug Discovery, vol.51, issue.9, pp.728-743, 2010.
DOI : 10.1038/nrd3228

R. Motterlini, P. Sawle, J. Hammad, S. Bains, R. Alberto et al., CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule, The FASEB Journal, vol.19, pp.284-286, 2005.
DOI : 10.1096/fj.04-2169fje

M. R. Mustafa and E. J. Johns, The role of haem oxygenase in renal vascular reactivity in normotensive and hypertensive rats, Journal of Hypertension, vol.19, issue.6, pp.1105-1111, 2001.
DOI : 10.1097/00004872-200106000-00016

J. F. Ndisang, H. E. Tabien, and R. Wang, Carbon monoxide and hypertension, Journal of Hypertension, vol.22, issue.6, pp.1057-1074, 2004.
DOI : 10.1097/00004872-200406000-00002

K. Ogawa, J. Sun, S. Taketani, O. Nakajima, C. Nishitani et al., Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1, The EMBO Journal, vol.20, issue.11, pp.2835-2843, 2001.
DOI : 10.1093/emboj/20.11.2835

R. M. Ogborne, S. A. Rushworth, and M. A. Connell, ??-Lipoic Acid-Induced Heme Oxygenase-1 Expression Is Mediated by Nuclear Factor Erythroid 2-Related Factor 2 and p38 Mitogen-Activated Protein Kinase in Human Monocytic Cells, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.25, issue.10, pp.2100-2105, 2005.
DOI : 10.1161/01.ATV.0000183745.37161.6e

Y. Ohara, T. Ohara, T. Ohrui, T. Morikawa, T. Asamura et al., Exhaled carbon monoxide levels in preschool-age children with episodic asthma, Pediatrics International, vol.42, issue.2, pp.227-232, 2012.
DOI : 10.1111/j.1442-200X.2011.03515.x

R. Ollinger and J. Pratschke, Role of heme oxygenase-1 in transplantation, Transplant International, vol.123, issue.Suppl., pp.1071-1081, 2010.
DOI : 10.1111/j.1432-2277.2010.01158.x

L. Opie, Reperfusion injury and its pharmacologic modification, Circulation, vol.80, issue.4, pp.1049-1062, 1989.
DOI : 10.1161/01.CIR.80.4.1049

L. E. Otterbein, F. H. Bach, J. Alam, M. Soares, T. Lu et al., Carbon monoxide has anti-inflammatory effects involving the mitogenactivated protein kinase pathway, Nat Med, vol.6, pp.422-428, 2000.

L. E. Otterbein, S. L. Otterbein, E. Ifedigbo, F. Liu, D. E. Morse et al., MKK3 Mitogen-Activated Protein Kinase Pathway Mediates Carbon Monoxide-Induced Protection Against Oxidant-Induced Lung Injury, The American Journal of Pathology, vol.163, issue.6, 2003.
DOI : 10.1016/S0002-9440(10)63610-3

K. S. Ozaki, G. M. Marques, E. Nogueira, R. Q. Feitoza, M. A. Cenedeze et al., Improved renal function after kidney transplantation is associated with heme oxygenase-1 polymorphism, Clinical Transplantation, vol.6, issue.Suppl. 1, pp.609-616, 2008.
DOI : 10.1111/j.1399-0012.2008.00832.x

P. Pacher, J. S. Beckman, and L. Liaudet, Nitric Oxide and Peroxynitrite in Health and Disease, Physiological Reviews, vol.87, issue.1, pp.315-424, 2007.
DOI : 10.1152/physrev.00029.2006

H. O. Pae, G. S. Oh, B. M. Choi, S. C. Chae, Y. M. Kim et al., Carbon Monoxide Produced by Heme Oxygenase-1 Suppresses T Cell Proliferation via Inhibition of IL-2 Production, The Journal of Immunology, vol.172, issue.8, pp.4744-4751, 2004.
DOI : 10.4049/jimmunol.172.8.4744

A. Paine, B. Eiz-vesper, R. Blasczyk, and S. Immenschuh, Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential, Biochemical Pharmacology, vol.80, issue.12, pp.1895-1903, 2010.
DOI : 10.1016/j.bcp.2010.07.014

URL : https://hal.archives-ouvertes.fr/hal-00637151

H. H. Patel and P. A. Insel, Lipid Rafts and Caveolae and Their Role in Compartmentation of Redox Signaling, Antioxidants & Redox Signaling, vol.11, issue.6, pp.1357-1372, 2009.
DOI : 10.1089/ars.2008.2365

C. Peers, Ion channels as target effectors for carbon monoxide, Experimental Physiology, vol.15, issue.9, pp.836-839, 2011.
DOI : 10.1113/expphysiol.2011.059063

C. Peers and D. S. Steele, Carbon monoxide: A vital signalling molecule and potent toxin in the myocardium, Journal of Molecular and Cellular Cardiology, vol.52, issue.2, pp.359-365, 2012.
DOI : 10.1016/j.yjmcc.2011.05.013

J. Peng, R. Lu, F. Ye, H. W. Deng, and Y. J. Li, The heme oxygenase-1 pathway is involved in calcitonin gene-related peptide-mediated delayed cardioprotection induced by monophosphoryl lipid A in rats, Regulatory Peptides, vol.103, issue.1, pp.1-7, 2002.
DOI : 10.1016/S0167-0115(01)00315-9

C. A. Piantadosi, Biological Chemistry of Carbon Monoxide, Antioxidants & Redox Signaling, vol.4, issue.2, pp.259-270, 2002.
DOI : 10.1089/152308602753666316

C. A. Piantadosi, Carbon monoxide, reactive oxygen signaling, and oxidative stress, Free Radical Biology and Medicine, vol.45, issue.5, pp.562-569, 2008.
DOI : 10.1016/j.freeradbiomed.2008.05.013

C. A. Piantadosi, L. Tatro, and J. Zhang, Hydroxyl radical production in the brain after CO hypoxia in rats, Free Radical Biology and Medicine, vol.18, issue.3, pp.603-609, 1995.
DOI : 10.1016/0891-5849(95)00168-W

M. D. Pizarro, J. V. Rodriguez, M. E. Mamprin, B. J. Fuller, B. E. Mann et al., Protective effects of a carbon monoxide-releasing molecule (CORM-3) during hepatic cold preservation, Cryobiology, vol.58, issue.3, pp.248-255, 2009.
DOI : 10.1016/j.cryobiol.2009.01.002

L. D. Prockop and R. I. Chichkova, Carbon monoxide intoxication: An updated review, Journal of the Neurological Sciences, vol.262, issue.1-2, pp.122-130, 2007.
DOI : 10.1016/j.jns.2007.06.037

S. Puntarulo, Iron, oxidative stress and human health, Molecular Aspects of Medicine, vol.26, issue.4-5, pp.299-312, 2005.
DOI : 10.1016/j.mam.2005.07.001

N. Radhakrishnan, S. P. Yadav, A. Sachdeva, P. K. Pruthi, S. Sawhney et al., Human Heme Oxygenase-1 Deficiency Presenting With Hemolysis, Nephritis, and Asplenia, Journal of Pediatric Hematology/Oncology, vol.33, issue.1, pp.74-78, 2011.
DOI : 10.1097/MPH.0b013e3181fd2aae

R. Radi, A. Cassina, R. Hodara, C. Quijano, and L. Castro, Peroxynitrite reactions and formation in mitochondria, Free Radical Biology and Medicine, vol.33, issue.11, pp.1451-1464, 2002.
DOI : 10.1016/S0891-5849(02)01111-5

R. Radi, G. Peluffo, M. N. Alvarez, M. Naviliat, and A. Cayota, Unraveling peroxynitrite formation in biological systems, Free Radical Biology and Medicine, vol.30, issue.5, pp.463-488, 2001.
DOI : 10.1016/S0891-5849(00)00373-7

D. C. Ramirez, S. E. Gomez-mejiba, and R. P. Mason, Mechanism of hydrogen peroxide-induced Cu,Zn-superoxide dismutase-centered radical formation as explored by immuno-spin trapping:, Free Radical Biology and Medicine, vol.38, issue.2, pp.201-214, 2005.
DOI : 10.1016/j.freeradbiomed.2004.10.008

C. M. Raval and P. J. Lee, Heme Oxygenase-1 in Lung Disease, Current Drug Targets, vol.11, issue.12, pp.1532-1540, 2010.
DOI : 10.2174/1389450111009011532

B. M. Reyes, S. Danese, M. Sans, C. Fiocchi, and A. D. Levine, Redox Equilibrium in Mucosal T Cells Tunes the Intestinal TCR Signaling Threshold, The Journal of Immunology, vol.175, issue.4, pp.2158-2166, 2005.
DOI : 10.4049/jimmunol.175.4.2158

M. A. Rhodes, M. S. Carraway, C. A. Piantadosi, C. M. Reynolds, A. D. Cherry et al., Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans, AJP: Heart and Circulatory Physiology, vol.297, issue.1, pp.392-399, 2009.
DOI : 10.1152/ajpheart.00164.2009

L. Rochette, E. Tatou, V. Maupoil, M. Zeller, Y. Cottin et al., Atrial and Vascular Oxidative Stress in Patients with Heart Failure, Cellular Physiology and Biochemistry, vol.27, issue.5, pp.497-502, 2011.
DOI : 10.1159/000329951

L. Rochette and C. Vergely, Forgotten radicals in biology, International Journal of Biomedical Sciences, vol.4, 2008.

L. Rochette and C. Vergely, Le sulfure d???hydrog??ne (H2S), un gaz endog??ne ?? l???odeur d?????uf pourri, pourrait ??tre un r??gulateur des fonctions cardiovasculaires, Annales de Cardiologie et d'Ang??iologie, vol.57, issue.3, pp.136-138, 2008.
DOI : 10.1016/j.ancard.2008.02.014

D. Rund and E. Rachmilewitz, New trends in the treatment of ??-thalassemia, Critical Reviews in Oncology/Hematology, vol.33, issue.2, pp.105-118, 2000.
DOI : 10.1016/S1040-8428(99)00058-X

S. W. Ryter, J. Alam, and A. M. Choi, Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications, Physiological Reviews, vol.86, issue.2, pp.583-650, 2006.
DOI : 10.1152/physrev.00011.2005

S. W. Ryter and A. M. Choi, Heme Oxygenase-1/Carbon Monoxide: Novel Therapeutic Strategies in Critical Care Medicine, Current Drug Targets, vol.11, issue.12, pp.1485-1494, 2010.
DOI : 10.2174/1389450111009011485

S. W. Ryter and L. E. Otterbein, Carbon monoxide in biology and medicine, BioEssays, vol.90, issue.3, pp.270-280, 2004.
DOI : 10.1002/bies.20005

T. Santos-silva, A. Mukhopadhyay, J. D. Seixas, G. J. Bernardes, C. C. Romao et al., CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl???Lysozyme Complex, Journal of the American Chemical Society, vol.133, issue.5, pp.1192-1195, 2011.
DOI : 10.1021/ja108820s

K. Sato, J. Balla, L. Otterbein, R. N. Smith, S. Brouard et al., Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants, The Journal of Immunology, vol.166, issue.6, pp.4185-4194, 2001.
DOI : 10.4049/jimmunol.166.6.4185

P. Sawle, R. Foresti, B. E. Mann, T. R. Johnson, C. J. Green et al., Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages, British Journal of Pharmacology, vol.103, issue.6, pp.800-810, 2005.
DOI : 10.1038/sj.bjp.0706241

F. Scalera, J. Martens-lobenhoffer, M. Tager, A. Bukowska, U. Lendeckel et al., Effect of l-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging, Biochemical and Biophysical Research Communications, vol.345, issue.3, pp.1075-1082, 2006.
DOI : 10.1016/j.bbrc.2006.05.015

G. Scapagnini, R. Foresti, V. Calabrese, G. Stella, A. M. Green et al., Caffeic Acid Phenethyl Ester and Curcumin: A Novel Class of Heme Oxygenase-1 Inducers, Molecular Pharmacology, vol.61, issue.3, pp.554-561, 2002.
DOI : 10.1124/mol.61.3.554

R. Schmidt, E. Tritschler, A. Hoetzel, T. Loop, M. Humar et al., Heme Oxygenase-1 Induction by the Clinically Used Anesthetic Isoflurane Protects Rat Livers From Ischemia/Reperfusion Injury, Annals of Surgery, vol.245, issue.6, pp.931-942, 2007.
DOI : 10.1097/01.sla.0000256891.45790.4d

H. Schuett, C. Eipel, C. Maletzki, M. D. Menger, and B. Vollmar, NO counterbalances HO-1 overexpression-induced acceleration of hepatocyte proliferation in mice, Laboratory Investigation, vol.110, pp.602-612, 2007.
DOI : 10.1038/labinvest.3700548

T. Shintani, T. Iwabuchi, T. Soga, Y. Kato, T. Yamamoto et al., Cystathionine ??-synthase as a carbon monoxide-sensitive regulator of bile excretion, Hepatology, vol.97, issue.1, pp.141-150, 2009.
DOI : 10.1002/hep.22604

P. Sicard, N. Acar, S. Gregoire, B. Lauzier, A. M. Bron et al., Influence of rosuvastatin on the NAD(P)H oxidase activity in the retina and electroretinographic response of spontaneously hypertensive rats, British Journal of Pharmacology, vol.263, issue.74, pp.979-986, 2007.
DOI : 10.1038/sj.bjp.0707322

P. Sicard, S. Delemasure, C. Korandji, A. Segueira-le-grand, B. Lauzier et al., Anti-hypertensive effects of Rosuvastatin are associated with decreased inflammation and oxidative stress markers in hypertensive rats, Free Radical Research, vol.197, issue.2, pp.226-236, 2008.
DOI : 10.1038/nature01158

D. J. Smith, H. Ng, R. M. Kluck, and P. Nagley, The mitochondrial gateway to cell death, IUBMB Life, vol.14, issue.6, pp.383-389, 2008.
DOI : 10.1002/iub.44

M. P. Soares, I. Marguti, A. Cunha, and R. Larsen, Immunoregulatory effects of HO-1: how does it work?, Current Opinion in Pharmacology, vol.9, issue.4, pp.482-489, 2009.
DOI : 10.1016/j.coph.2009.05.008

J. P. Spencer, K. Vafeiadou, R. J. Williams, and D. Vauzour, Neuroinflammation: Modulation by flavonoids and mechanisms of action, Molecular Aspects of Medicine, vol.33, issue.1, pp.83-97, 2012.
DOI : 10.1016/j.mam.2011.10.016

K. Srisook, S. S. Han, H. S. Choi, M. H. Li, H. Ueda et al., CO from enhanced HO activity or from CORM-2 inhibits both O2??? and NO production and downregulates HO-1 expression in LPS-stimulated macrophages, Biochemical Pharmacology, vol.71, issue.3, pp.307-318, 2006.
DOI : 10.1016/j.bcp.2005.10.042

S. Sueur, M. Pesant, L. Rochette, and J. L. Connat, Antiapoptotic effect of calcitonin gene-related peptide on oxidative stress-induced injury in H9c2 cardiomyocytes via the RAMP1/CRLR complex, Journal of Molecular and Cellular Cardiology, vol.39, issue.6, pp.955-963, 2005.
DOI : 10.1016/j.yjmcc.2005.09.008

N. B. Surmeli, N. K. Litterman, A. F. Miller, and J. T. Groves, Peroxynitrite Mediates Active Site Tyrosine Nitration in Manganese Superoxide Dismutase. Evidence of a Role for the Carbonate Radical Anion, Journal of the American Chemical Society, vol.132, issue.48, 2010.
DOI : 10.1021/ja105684w

C. Taille, J. El-benna, S. Lanone, J. Boczkowski, and R. Motterlini, Mitochondrial Respiratory Chain and NAD(P)H Oxidase Are Targets for the Antiproliferative Effect of Carbon Monoxide in Human Airway Smooth Muscle, Journal of Biological Chemistry, vol.280, issue.27, pp.25350-25360, 2005.
DOI : 10.1074/jbc.M503512200

S. R. Thom, D. Fisher, Y. A. Xu, S. Garner, and H. Ischiropoulos, Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat, American Journal of Physiology, vol.276, pp.984-992, 1999.

S. R. Thom, D. Fisher, Y. A. Xu, K. Notarfrancesco, and H. Ischiropoulos, Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide, Proceedings of the National Academy of Sciences, vol.97, issue.3, pp.1305-1310, 2000.
DOI : 10.1073/pnas.97.3.1305

S. Tzima, P. Victoratos, K. Kranidioti, M. Alexiou, and G. Kollias, Myeloid heme oxygenase???1 regulates innate immunity and autoimmunity by modulating IFN-?? production, The Journal of Experimental Medicine, vol.206, issue.5, pp.1167-1179, 2009.
DOI : 10.1172/JCI200319079

J. Varadi, I. Lekli, B. Juhasz, I. Bacskay, G. Szabo et al., Beneficial effects of carbon monoxide-releasing molecules on post-ischemic myocardial recovery, Life Sciences, vol.80, issue.17, pp.1619-1626, 2007.
DOI : 10.1016/j.lfs.2007.01.047

C. Vergely, V. Maupoil, G. Clermont, A. Bril, and L. Rochette, Identification and quantification of free radicals during myocardial ischemia and reperfusion using electron paramagnetic resonance spectroscopy, Archives of Biochemistry and Biophysics, vol.420, issue.2, pp.209-216, 2003.
DOI : 10.1016/j.abb.2003.07.007

C. Vergely, C. Perrin-sarrado, G. Clermont, and L. Rochette, Postischemic Recovery and Oxidative Stress Are Independent of Nitric-Oxide Synthases Modulation in Isolated Rat Heart, Journal of Pharmacology and Experimental Therapeutics, vol.303, issue.1, pp.149-157, 2002.
DOI : 10.1124/jpet.102.036871

C. Vergely, C. Renard, D. Moreau, V. Roubaud, B. Tuccio et al., Effect of two new PBN-derived phosphorylated nitrones against postischaemic ventricular dysrhythmias, Fundamental and Clinical Pharmacology, vol.2, issue.4, pp.433-442, 2003.
DOI : 10.1016/0891-5849(93)90003-D

G. Wang, T. Hamid, R. J. Keith, G. Zhou, C. R. Partridge et al., Cardioprotective and Antiapoptotic Effects of Heme Oxygenase-1 in the Failing Heart, Circulation, vol.121, issue.17, pp.1912-1925, 2010.
DOI : 10.1161/CIRCULATIONAHA.109.905471

L. J. Wang, T. S. Lee, F. Y. Lee, R. C. Pai, and L. Y. Chau, Expression of heme oxygenase-1 in atherosclerotic lesions, Am J Pathol, vol.152, pp.711-720, 1998.

R. Wang, Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?, The FASEB Journal, vol.16, issue.13, pp.1792-1798, 2002.
DOI : 10.1096/fj.02-0211hyp

X. Wang, Y. Wang, H. P. Kim, K. Nakahira, S. W. Ryter et al., Carbon Monoxide Protects against Hyperoxia-induced Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Formation, Journal of Biological Chemistry, vol.282, issue.3, pp.1718-1726, 2007.
DOI : 10.1074/jbc.M607610200

X. M. Wang, H. P. Kim, K. Nakahira, S. W. Ryter, and A. M. Choi, The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1, The Journal of Immunology, vol.182, issue.6, pp.3809-3818, 2009.
DOI : 10.4049/jimmunol.0712437

Y. Watari, Y. Yamamoto, A. Brydun, T. Ishida, S. Mito et al., Ablation of the Bach1 Gene Leads to the Suppression of Atherosclerosis in Bach1 and Apolipoprotein E Double Knockout Mice, Hypertension Research, vol.31, issue.4, pp.783-792, 2008.
DOI : 10.1291/hypres.31.783

R. N. Watts, P. Ponka, and D. R. Richardson, Effects of nitrogen monoxide and carbon monoxide on molecular and cellular iron metabolism: mirror-image effector molecules that target iron, Biochemical Journal, vol.369, issue.3, pp.429-440, 2003.
DOI : 10.1042/bj20021302

B. Wegiel, D. J. Gallo, K. G. Raman, J. M. Karlsson, B. Ozanich et al., Nitric Oxide-Dependent Bone Marrow Progenitor Mobilization by Carbon Monoxide Enhances Endothelial Repair After Vascular Injury, Circulation, vol.121, issue.4, pp.537-548, 2010.
DOI : 10.1161/CIRCULATIONAHA.109.887695

M. Whiteman and P. K. Moore, Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability?, Journal of Cellular and Molecular Medicine, vol.121, issue.3, pp.488-507, 2009.
DOI : 10.1111/j.1582-4934.2009.00645.x

W. J. Wilkinson and P. J. Kemp, Carbon monoxide: an emerging regulator of ion channels, The Journal of Physiology, vol.285, issue.13, pp.3055-3062, 2011.
DOI : 10.1113/jphysiol.2011.206706

D. Willis, A. R. Moore, R. Frederick, and D. A. Willoughby, Heme oxygenase: A novel target for the modulation of inflammatory response, Nature Medicine, vol.72, issue.1, pp.87-90, 1996.
DOI : 10.1038/nm0196-87

C. H. Woo and J. Abe, SUMO???a post-translational modification with therapeutic potential?, Current Opinion in Pharmacology, vol.10, issue.2, pp.146-155, 2010.
DOI : 10.1016/j.coph.2009.12.001

C. H. Woo, M. P. Massett, T. Shishido, S. Itoh, B. Ding et al., ERK5 Activation Inhibits Inflammatory Responses via Peroxisome Proliferator-activated Receptor ?? (PPAR??) Stimulation, Journal of Biological Chemistry, vol.281, issue.43, pp.32164-32174, 2006.
DOI : 10.1074/jbc.M602369200

I. Wortzel and R. Seger, The ERK Cascade: Distinct Functions within Various Subcellular Organelles, Genes & Cancer, vol.2, issue.3, pp.195-209, 2011.
DOI : 10.1177/1947601911407328

M. M. Wright, J. Kim, T. D. Hock, N. Leitinger, B. A. Freeman et al., Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions, Biochemical Journal, vol.13, issue.2, pp.353-361, 2009.
DOI : 10.1146/annurev.biochem.66.1.807

M. M. Wright, F. J. Schopfer, P. R. Baker, V. Vidyasagar, P. Powell et al., Fatty acid transduction of nitric oxide signaling: Nitrolinoleic acid potently activates endothelial heme oxygenase 1 expression, Proceedings of the National Academy of Sciences, vol.103, issue.11, pp.4299-4304, 2006.
DOI : 10.1073/pnas.0506541103

B. J. Wu, R. G. Midwinter, C. Cassano, K. Beck, Y. Wang et al., Heme Oxygenase-1 Increases Endothelial Progenitor Cells, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.29, issue.10, pp.1537-1542, 2009.
DOI : 10.1161/ATVBAHA.109.184713

L. Wu, K. Cao, Y. Lu, and R. Wang, Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide, Journal of Clinical Investigation, vol.110, issue.5, pp.691-700, 2002.
DOI : 10.1172/JCI0215316

L. Wu and R. Wang, Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications, Pharmacological Reviews, vol.57, issue.4, pp.585-630, 2005.
DOI : 10.1124/pr.57.4.3

M. L. Wu, Y. C. Ho, C. Y. Lin, and S. F. Yet, Heme oxygenase-1 in inflammation and cardiovascular disease, Am J Cardiovasc Dis, vol.1, pp.150-158, 2011.

M. L. Wu, Y. C. Ho, and S. F. Yet, A Central Role of Heme Oxygenase-1 in Cardiovascular Protection, Antioxidants & Redox Signaling, vol.15, issue.7, pp.1835-1846, 2011.
DOI : 10.1089/ars.2010.3726

K. Yamashita, R. Ollinger, J. Mcdaid, H. Sakahama, H. Wang et al., Heme oxygenase-1 is essential for and promotes tolerance to transplanted organs, The FASEB Journal, vol.20, pp.776-778, 2006.
DOI : 10.1096/fj.05-4791fje

L. Yang, S. Quan, A. Nasjletti, M. Laniado-schwartzman, and N. G. Abraham, Heme Oxygenase-1 Gene Expression Modulates Angiotensin II-Induced Increase in Blood Pressure, Hypertension, vol.43, issue.6, pp.1221-1226, 2004.
DOI : 10.1161/01.hyp.0000126287.62060.e6

F. Ye, P. Y. Deng, D. Li, D. Luo, N. S. Li et al., Involvement of endothelial cell-derived CGRP in heat stress-induced protection of endothelial function, Vascular Pharmacology, vol.46, issue.4, pp.238-246, 2007.
DOI : 10.1016/j.vph.2006.10.008

L. J. Young and W. S. Caughey, Oxygenation of carbon monoxide by bovine heart cytochrome c oxidase, Biochemistry, vol.25, issue.1, pp.152-161, 1986.
DOI : 10.1021/bi00349a022

M. Zeller, C. Korandji, J. C. Guilland, P. Sicard, C. Vergely et al., Impact of Asymmetric Dimethylarginine on Mortality After Acute Myocardial Infarction, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.28, issue.5, pp.954-960, 2008.
DOI : 10.1161/ATVBAHA.108.162768

H. Zhang, C. Andrekopoulos, J. Joseph, J. Crow, and B. Kalyanaraman, The carbonate radical anion-induced covalent aggregation of human copper, zinc superoxide dismutase, and ??-synuclein: intermediacy of tryptophan- and tyrosine-derived oxidation products, Free Radical Biology and Medicine, vol.36, issue.11, pp.1355-1365, 2004.
DOI : 10.1016/j.freeradbiomed.2004.02.038

J. Zhang, X. Yao, R. Yu, J. Bai, Y. Sun et al., Exhaled carbon monoxide in asthmatics: a meta-analysis, Respiratory Research, vol.124, issue.5, p.50, 2010.
DOI : 10.1378/chest.124.5.1749

W. Q. Zhang, A. C. Whitwood, I. J. Fairlamb, and J. M. Lynam, Group 6 Carbon Monoxide-Releasing Metal Complexes with Biologically-Compatible Leaving Groups, Inorganic Chemistry, vol.49, issue.19, pp.8941-8952, 2010.
DOI : 10.1021/ic101230j

X. Zhang, P. Shan, J. Alam, R. J. Davis, R. A. Flavell et al., Carbon Monoxide Modulates Fas/Fas Ligand, Caspases, and Bcl-2 Family Proteins via the p38?? Mitogen-activated Protein Kinase Pathway during Ischemia-Reperfusion Lung Injury, Journal of Biological Chemistry, vol.278, issue.24, pp.22061-22070, 2003.
DOI : 10.1074/jbc.M301858200

X. Zhang, P. Shan, J. Alam, X. Y. Fu, and P. J. Lee, Carbon Monoxide Differentially Modulates STAT1 and STAT3 and Inhibits Apoptosis via a Phosphatidylinositol 3-Kinase/Akt and p38 Kinase-dependent STAT3 Pathway during Anoxia-Reoxygenation Injury, Journal of Biological Chemistry, vol.280, issue.10, pp.8714-8721, 2005.
DOI : 10.1074/jbc.M408092200

S. Zhou, Z. Cui, and J. P. Urban, Factors influencing the oxygen concentration gradient from the synovial surface of articular cartilage to the cartilage-bone interface: A modeling study, Arthritis & Rheumatism, vol.14, issue.12, pp.3915-3924, 2004.
DOI : 10.1002/art.20675

Z. Zhou, R. Song, C. L. Fattman, S. Greenhill, S. Alber et al., Carbon Monoxide Suppresses Bleomycin-Induced Lung Fibrosis, The American Journal of Pathology, vol.166, issue.1, pp.27-37, 2005.
DOI : 10.1016/S0002-9440(10)62229-8

C. Ziskoven, M. Jager, J. Kircher, T. Patzer, W. Bloch et al., Physiology and pathophysiology of nitrosative and oxidative stress in osteoarthritic joint destruction, Canadian Journal of Physiology and Pharmacology, vol.89, issue.7, pp.455-466, 2011.
DOI : 10.1139/y11-055

B. S. Zuckerbraun, B. Y. Chin, B. Wegiel, T. R. Billiar, E. Czsimadia et al., Carbon monoxide reverses established pulmonary hypertension, The Journal of Experimental Medicine, vol.267, issue.9, pp.2109-2119, 2006.
DOI : 10.1172/JCI23203

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118401

B. S. Zuckerbraun, C. A. Mccloskey, D. Gallo, F. Liu, E. Ifedigbo et al., Carbon monoxide prevents multiple organ injury in a model of hemorrhagic shock and resuscitation, Shock, vol.23, pp.527-532, 2005.