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Neuronal architectures with axo-dendritic polarity above silicon nanowires.

Sophie Roth 1 Ghislain Bugnicourt 2 Mariano Bisbal 3 Sylvie Gory-Fauré 3 Jacques Brocard 3 Catherine Villard 4, *
* Corresponding author
1 INSERM U836, équipe 1, Physiopathologie du cytosquelette
GIN - Grenoble Institut des Neurosciences, NEEL [2007-2015] - Institut Néel [2007-2015]
2 INSERM U836, équipe 1, Physiopathologie du cytosquelette
GPC - Groupe Physiopathologie du Cytosquelette, GIN - Grenoble Institut des Neurosciences, NEEL [2007-2015] - Institut Néel [2007-2015]
3 INSERM U836, équipe 1, Physiopathologie du cytosquelette
GIN - Grenoble Institut des Neurosciences
Abstract : An approach is developped to gain control over the polarity of neuronal networks at the cellular level by physically constraining cell development by the use of micropatterns. It is demonstrated that the position and path of individual axons, the cell extension that propagates the neuron output signal, can be chosen with a success rate higher than 85%. This allows the design of small living computational blocks above silicon nanowires.
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https://www.hal.inserm.fr/inserm-00734705
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Submitted on : Monday, September 24, 2012 - 12:25:39 PM
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Sophie Roth, Ghislain Bugnicourt, Mariano Bisbal, Sylvie Gory-Fauré, Jacques Brocard, et al.. Neuronal architectures with axo-dendritic polarity above silicon nanowires.. Small, Wiley-VCH Verlag, 2012, 8 (5), pp.671-5. ⟨10.1002/smll.201102325⟩. ⟨inserm-00734705⟩

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