Early Life Blockade of 5-Hydroxytryptamine 1A Receptors Normalizes Sleep and Depression-Like Behavior in Adult Knock-Out Mice Lacking the Serotonin Transporter, Journal of Neuroscience, vol.26, issue.20, pp.5554-5564, 2006. ,
DOI : 10.1523/JNEUROSCI.5156-05.2006
The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders, Genes & Development, vol.16, issue.18, pp.2350-2364, 2002. ,
DOI : 10.1101/gad.223302
Microtubule Stabilizer Ameliorates Synaptic Function and Behavior in a Mouse Model for Schizophrenia, Biological Psychiatry, vol.60, issue.11, pp.1224-1230, 2006. ,
DOI : 10.1016/j.biopsych.2006.03.048
URL : https://hal.archives-ouvertes.fr/inserm-00380045
Inhibition of Serotonin But Not Norepinephrine Transport during Development Produces Delayed, Persistent Perturbations of Emotional Behaviors in Mice, Journal of Neuroscience, vol.28, issue.1, pp.199-207, 2008. ,
DOI : 10.1523/JNEUROSCI.3973-07.2008
knockout, Journal of Neurochemistry, vol.21, issue.3, pp.619-630, 2001. ,
DOI : 10.1046/j.1471-4159.2001.00437.x
Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders, Molecular Psychiatry, vol.115, issue.3, pp.293-306, 2010. ,
DOI : 10.1038/sj.mp.4001574
Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency, Proc. Natl. Acad. Sci. USA 105, pp.1333-1338, 2008. ,
Post-pubertal emergence of alterations in locomotor activity in stop null mice, Synapse, vol.177, issue.9, pp.689-697, 2007. ,
DOI : 10.1002/syn.20409
URL : https://hal.archives-ouvertes.fr/inserm-00379954
The stop null mice model for schizophrenia displays cognitive and social deficits partly alleviated by neuroleptics, Neuroscience, vol.157, issue.1, pp.29-39, 2008. ,
DOI : 10.1016/j.neuroscience.2008.07.080
URL : https://hal.archives-ouvertes.fr/inserm-00375621
The genetic basis of the pharmacological effects of anxiolytics: a review based on rodent models, Behavioural Pharmacology, vol.12, issue.6, pp.451-460, 2001. ,
DOI : 10.1097/00008877-200111000-00005
Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory', Nature Protocols, vol.37, issue.3, pp.1306-1311, 2006. ,
DOI : 10.1038/nprot.2006.205
Are some genetic risk factors common to schizophrenia, bipolar disorder and depression? evidence fromDISC1, GRIK4 andNRG1, Neurotoxicity Research, vol.41, issue.2, pp.73-83, 2007. ,
DOI : 10.1007/BF03033484
Sustained increase of alpha7 nicotinic receptors and choline-induced improvement of learning deficit in STOP knock-out mice, Neuropharmacology, vol.52, issue.8, pp.1691-1700, 2007. ,
DOI : 10.1016/j.neuropharm.2007.03.015
URL : https://hal.archives-ouvertes.fr/inserm-00379958
Hypoglutamatergic activity in the STOP knockout mouse: A potential model for chronic untreated schizophrenia, Journal of Neuroscience Research, vol.18, issue.15, pp.3487-3493, 2007. ,
DOI : 10.1002/jnr.21200
URL : https://hal.archives-ouvertes.fr/inserm-00379976
Molecular and Cellular Cognition, Cell, vol.117, issue.1, pp.3-4, 2004. ,
DOI : 10.1016/S0092-8674(04)00295-8
URL : http://doi.org/10.1016/s0092-8674(04)00295-8
Dopaminergic transmission in STOP null mice, Journal of Neurochemistry, vol.65, issue.1, pp.63-73, 2005. ,
DOI : 10.1016/0165-0173(90)90015-G
URL : https://hal.archives-ouvertes.fr/inserm-00380189
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia, Proc. Natl Acad. Sci. USA, pp.8627-8632, 2005. ,
DOI : 10.1073/pnas.0500515102
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia, Molecular Psychiatry, vol.114, issue.1, pp.74-86, 2007. ,
DOI : 10.1016/0169-328X(94)00247-C
Heritability Estimates for Psychotic Disorders, Archives of General Psychiatry, vol.56, issue.2, pp.162-168, 1999. ,
DOI : 10.1001/archpsyc.56.2.162
The psychoses: Cluster 3 of the proposed meta-structure for DSM-V and ICD-11, Psychological Medicine, vol.102, issue.12, pp.2025-2042, 2009. ,
DOI : 10.1093/brain/122.4.593
A Spontaneous Point Mutation Produces Monoamine Oxidase A/B Knock-out Mice with Greatly Elevated Monoamines and Anxiety-like Behavior, Journal of Biological Chemistry, vol.279, issue.38, pp.39645-39652, 2004. ,
DOI : 10.1074/jbc.M405550200
Behavioral Phenotypes of Disc1 Missense Mutations in Mice, Neuron, vol.54, issue.3, pp.387-402, 2007. ,
DOI : 10.1016/j.neuron.2007.04.015
The beginning of the end for the Kraepelinian dichotomy, The British Journal of Psychiatry, vol.186, issue.5, pp.364-366, 2005. ,
DOI : 10.1192/bjp.186.5.364
Genes for Schizophrenia and Bipolar Disorder? Implications for Psychiatric Nosology, Schizophrenia Bulletin, vol.32, issue.1, pp.9-16, 2006. ,
DOI : 10.1093/schbul/sbj033
Effects of S-21007, a potent 5-HT3 partial agonist, in mouse anxiety, Zhongguo Yao Li Xue Bao, vol.20, pp.805-812, 1999. ,
Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice, Psychopharmacology, vol.84, issue.1, pp.131-141, 2010. ,
DOI : 10.1007/s00213-009-1712-3
URL : https://hal.archives-ouvertes.fr/inserm-00447474
Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice, Neuropharmacology, vol.55, issue.6, pp.1006-1014, 2008. ,
DOI : 10.1016/j.neuropharm.2008.08.001
Mice mutant for genes associated with schizophrenia: Common phenotype or distinct endophenotypes?, Behavioural Brain Research, vol.204, issue.2, pp.258-273, 2009. ,
DOI : 10.1016/j.bbr.2009.04.001
Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants, Psychopharmacology, vol.101, issue.1, pp.66-72, 1995. ,
DOI : 10.1007/BF02245592
Effect of Antidepressant Drugs in Mice Lacking the Norepinephrine Transporter, Neuropsychopharmacology, vol.68, issue.11, pp.2424-2432, 2006. ,
DOI : 10.1038/sj.npp.1301064
Altered expression of synaptic protein mRNAs in STOP (MAP6) mutant mice, Journal of Psychopharmacology, vol.105, issue.6, pp.635-644, 2007. ,
DOI : 10.1177/0269881106068825
URL : https://hal.archives-ouvertes.fr/inserm-00380032
Insights into the Role of Dopamine Receptor Systems in Learning and Memory, Reviews in the Neurosciences, vol.18, issue.1, pp.37-66, 2007. ,
DOI : 10.1515/REVNEURO.2007.18.1.37
receptors in knock-out mice lacking the 5-HT transporter, European Journal of Neuroscience, vol.52, issue.Suppl.2, pp.2299-2310, 2000. ,
DOI : 10.1046/j.1460-9568.2000.00126.x
The deletion of the microtubule-associated STOP protein affects the serotonergic mouse brain network, Journal of Neurochemistry, vol.12, issue.Suppl, pp.1579-1594, 2010. ,
DOI : 10.1111/j.1471-4159.2010.07064.x
URL : https://hal.archives-ouvertes.fr/inserm-00566974
STOP knockout and NMDA NR1 hypomorphic mice exhibit deficits in sensorimotor gating, Behavioural Brain Research, vol.163, issue.2, pp.257-264, 2005. ,
DOI : 10.1016/j.bbr.2005.05.012
URL : https://hal.archives-ouvertes.fr/inserm-00380197
The Mouse Brain in Stereotaxic Coordinates, 1997. ,
Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine, J. Neurosci, vol.22, pp.8771-8777, 2002. ,
Vmat2 Heterozygous Mutant Mice Display a Depressive-Like Phenotype, Journal of Neuroscience, vol.27, issue.39, pp.10520-10529, 2007. ,
DOI : 10.1523/JNEUROSCI.4388-06.2007
Serotonin/dopamine interaction in memory formation, Prog. Brain Res, vol.172, pp.603-623, 2008. ,
DOI : 10.1016/S0079-6123(08)00928-X
The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone, Nature Neuroscience, vol.28, issue.3, pp.292-300, 2008. ,
DOI : 10.1038/nn2052
URL : https://hal.archives-ouvertes.fr/hal-00263930
The effects of compounds varying in selectivity as 5-HT1A receptor antagonists in three rat models of anxiety, Neuropharmacology, vol.39, issue.10, pp.1848-1857, 2000. ,
DOI : 10.1016/S0028-3908(00)00074-5
Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult, Nature, vol.272, issue.6879, pp.396-400, 2002. ,
DOI : 10.1038/416396a
Deletion of the STOP gene, a microtubule stabilizing factor, leads only to discrete cerebral metabolic changes in mice, Journal of Neuroscience Research, vol.246, issue.4, pp.813-820, 2008. ,
DOI : 10.1002/jnr.21550
URL : https://hal.archives-ouvertes.fr/inserm-00375633
Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression, Biological Psychiatry, vol.54, issue.10, pp.953-959, 2003. ,
DOI : 10.1016/j.biopsych.2003.09.003
Tryptophan depletion impairs object-recognition memory in the rat: Reversal by risperidone, Behavioural Brain Research, vol.208, issue.2, pp.479-483, 2010. ,
DOI : 10.1016/j.bbr.2009.12.030
Increased Expression of the 5-HT Transporter Confers a Low- Anxiety Phenotype Linked to Decreased 5-HT Transmission, Journal of Neuroscience, vol.26, issue.35, pp.8955-8964, 2006. ,
DOI : 10.1523/JNEUROSCI.5356-05.2006
Role of dysbindin in dopamine receptor trafficking and cortical GABA function, Proc. Natl. Acad. Sci. USA, 2009. ,
DOI : 10.1073/pnas.0904289106
Nitric oxide synthase mediates the ability of darbepoetin alfa to improve the cognitive performance of STOP null mice, Neuropsychopharmacology, vol.35, pp.1718-1728, 2010. ,
Hypolocomotion, anxiety and serotonin syndrome-like behavior, 2007. ,
Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes, Neuroscience & Biobehavioral Reviews, vol.34, issue.3, pp.373-386, 2010. ,
DOI : 10.1016/j.neubiorev.2009.08.003
Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication, Archives of General Psychiatry, vol.62, issue.6, pp.617-627, 2005. ,
DOI : 10.1001/archpsyc.62.6.617
Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter, Neuropharmacology, vol.49, issue.6, pp.798-810, 2005. ,
DOI : 10.1016/j.neuropharm.2005.08.010
Dissociation of the effects of scopolamine and d-amphetamine on a spontaneous alternation task, Pharmacology Biochemistry and Behavior, vol.5, issue.3, pp.293-297, 1976. ,
DOI : 10.1016/0091-3057(76)90081-2
Reduced anxiety-related behaviour in transgenic mice overexpressing serotonin1A receptors, Molecular Brain Research, vol.129, issue.1-2, pp.104-116, 2004. ,
DOI : 10.1016/j.molbrainres.2004.06.028
A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition, Proc. Natl. Acad. Sci. USA 105, pp.7076-7081, 2008. ,
DOI : 10.1073/pnas.0802615105
Corticosteroid???serotonin interactions in the neurobiological mechanisms of stress-related disorders, Neuroscience & Biobehavioral Reviews, vol.32, issue.6, pp.1174-1184, 2008. ,
DOI : 10.1016/j.neubiorev.2008.04.006
The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches, Biological Psychiatry, vol.50, issue.11, pp.884-897, 2001. ,
DOI : 10.1016/S0006-3223(01)01303-8
Opposing alterations in anxiety and species-typical behaviours in serotonin transporter overexpressor and knockout mice, European Neuropsychopharmacology, vol.21, issue.1, pp.108-116, 2010. ,
DOI : 10.1016/j.euroneuro.2010.08.005
Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice, Biological Psychiatry, vol.54, issue.10, pp.960-971, 2003. ,
DOI : 10.1016/S0006-3223(03)00696-6
Schizophrenia and bipolar disorder: differences and overlaps, Current Opinion in Psychiatry, vol.19, issue.2, pp.165-170, 2006. ,
DOI : 10.1097/01.yco.0000214342.52249.82
Anxiolytic-like effects of DOI microinjections into the hippocampus (but not the amygdala nor the PAG) in the mice four plates test, Behavioural Brain Research, vol.188, pp.291-297, 2008. ,
DOI : 10.1016/j.bbr.2007.11.005
NAP (davunetide) enhances cognitive behavior in the STOP heterozygous mouse???A microtubule-deficient model of schizophrenia, Peptides, vol.31, issue.7, pp.1368-1373, 2010. ,
DOI : 10.1016/j.peptides.2010.04.011
URL : https://hal.archives-ouvertes.fr/inserm-00498115
S33005, a novel ligand at both serotonin and norepinephrine transporters: II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine, J. Pharmacol. Exp. Ther, vol.298, pp.581-591, 2001. ,
Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse, Trends in Neurosciences, vol.24, issue.8, pp.479-486, 2001. ,
DOI : 10.1016/S0166-2236(00)01862-2
Parallel Loss of Hippocampal LTD and Cognitive Flexibility in a Genetic Model of Hyperdopaminergia, Neuropsychopharmacology, vol.41, issue.10, pp.2108-2116, 2007. ,
DOI : 10.1038/sj.npp.1301354
URL : https://hal.archives-ouvertes.fr/inserm-00166900
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation, Human Molecular Genetics, vol.12, issue.13, pp.1591-1608, 2003. ,
DOI : 10.1093/hmg/ddg162
A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophrenia Res, pp.405-416, 2004. ,
Dopamine and the regulation of cognition and attention, Progress in Neurobiology, vol.67, issue.1, pp.53-83, 2002. ,
DOI : 10.1016/S0301-0082(02)00011-4
URL : https://hal.archives-ouvertes.fr/hal-00307886
Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits, Neuron, vol.65, issue.4, pp.480-489, 2010. ,
DOI : 10.1016/j.neuron.2010.01.019
A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders, Neuroscience, vol.152, issue.3, pp.573-584, 2008. ,
DOI : 10.1016/j.neuroscience.2007.12.032
Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and raphe nuclei, J. Neurosci, vol.17, pp.1710-1719, 1997. ,
Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions, Behavioural Pharmacology, vol.19, issue.5-6, pp.566-574, 2008. ,
DOI : 10.1097/FBP.0b013e32830cd80f
Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia, Molecular Psychiatry, vol.33, issue.2, pp.173-186, 2008. ,
DOI : 10.1016/S0166-2236(00)01886-5
Lasting Syndrome of Depression Produced by Reduction in Serotonin Uptake during Postnatal Development: Evidence from Sleep, Stress, and Behavior, Journal of Neuroscience, vol.28, issue.14, pp.3546-3554, 2008. ,
DOI : 10.1523/JNEUROSCI.4006-07.2008
Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity, European Journal of Pharmacology, vol.57, issue.2-3, pp.201-210, 1979. ,
DOI : 10.1016/0014-2999(79)90366-2
Disrupted in schizophrenia 1: building brains and memories, Trends in Molecular Medicine, vol.12, issue.6, pp.255-261, 2006. ,
DOI : 10.1016/j.molmed.2006.04.009
Cognitive impairments in the STOP null mouse model of schizophrenia., Behavioral Neuroscience, vol.121, issue.5, pp.826-835, 2007. ,
DOI : 10.1037/0735-7044.121.5.826
URL : https://hal.archives-ouvertes.fr/inserm-00380034
Suicidal Behavior in Patients With Schizophrenia and Other Psychotic Disorders, American Journal of Psychiatry, vol.156, issue.10, pp.1590-1595, 1999. ,
DOI : 10.1176/ajp.156.10.1590
Serotonin-1A Autoreceptors Are Necessary and Sufficient for the Normal Formation of Circuits Underlying Innate Anxiety, Journal of Neuroscience, vol.31, issue.16, pp.6008-6018, 2011. ,
DOI : 10.1523/JNEUROSCI.5836-10.2011
Neurobiology of Schizophrenia, Neuron, vol.52, issue.1, pp.139-153, 2006. ,
DOI : 10.1016/j.neuron.2006.09.015
Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants, PLoS ONE, vol.29, issue.10, p.3301, 2008. ,
DOI : 10.1371/journal.pone.0003301.s004
Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness, Neuroscience, vol.164, issue.4, pp.1431-1443, 2009. ,
DOI : 10.1016/j.neuroscience.2009.09.059
Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice, Behavioural Pharmacology, vol.11, issue.3 & 4, pp.279-290, 2000. ,
DOI : 10.1097/00008877-200006000-00011
URL : https://hal.archives-ouvertes.fr/inserm-00126162
The sandy (sdy) mouse: a dysbindin-1 mutant relevant to schizophrenia research, Prog. Brain Res, vol.179, pp.87-94, 2009. ,
DOI : 10.1016/S0079-6123(09)17910-4
Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin, Human Molecular Genetics, vol.15, issue.20, pp.3041-3054, 2006. ,
DOI : 10.1093/hmg/ddl246
Nicotine Improves Cognitive Deficits of Dopamine Transporter Knockout Mice without Long-Term Tolerance, Neuropsychopharmacology, vol.18, issue.12, pp.2465-2478, 2007. ,
DOI : 10.1038/sj.npp.1301385
Animal models as simulations of depression, Trends in Pharmacological Sciences, vol.12, pp.131-136, 1991. ,
DOI : 10.1016/0165-6147(91)90529-2
Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey, Behavioural Brain Research, vol.193, issue.1, pp.140-143, 2008. ,
DOI : 10.1016/j.bbr.2008.04.021