Skip to Main content Skip to Navigation
Journal articles

The anaemia of Plasmodium vivax malaria.

Abstract : ABSTRACT: Plasmodium vivax threatens nearly half the world's population and is a significant impediment to achievement of the millennium development goals. It is an important, but incompletely understood, cause of anaemia. This review synthesizes current evidence on the epidemiology, pathogenesis, treatment and consequences of vivax-associated anaemia. Young children are at high risk of clinically significant and potentially severe vivaxassociated anaemia, particularly in countries where transmission is intense and relapses are frequent. Despite reaching lower densities than Plasmodium falciparum, Plasmodium vivax causes similar absolute reduction in red blood cell mass because it results in proportionately greater removal of uninfected red blood cells. Severe vivax anaemia is associated with substantial indirect mortality and morbidity through impaired resilience to co-morbidities, obstetric complications and requirement for blood transfusion. Anaemia can be averted by early and effective anti-malarial treatment.
Document type :
Journal articles
Complete list of metadatas

https://www.hal.inserm.fr/inserm-00730637
Contributor : Ed. Bmc <>
Submitted on : Monday, September 10, 2012 - 5:06:39 PM
Last modification on : Friday, October 23, 2020 - 4:41:31 PM
Long-term archiving on: : Tuesday, December 11, 2012 - 3:41:42 AM

Files

Identifiers

Citation

Nicholas Douglas, Nicholas Anstey, Pierre Buffet, Jeanne Poespoprodjo, Tsin Yeo, et al.. The anaemia of Plasmodium vivax malaria.. Malaria Journal, BioMed Central, 2012, 11 (1), pp.135. ⟨10.1186/1475-2875-11-135⟩. ⟨inserm-00730637⟩

Share

Metrics

Record views

462

Files downloads

1113