R. Kyle and S. Rajkumar, Multiple Myeloma, New England Journal of Medicine, vol.351, issue.18, pp.1860-1873, 2004.
DOI : 10.1056/NEJMra041875

URL : https://hal.archives-ouvertes.fr/hal-00557757

B. Barlogie, G. Tricot, and F. Van-rhee, Long-term outcome results of the first tandem autotransplant trial for multiple myeloma, British Journal of Haematology, vol.86, issue.2, pp.158-164, 2006.
DOI : 10.1182/blood.V99.5.1745

K. Neben, H. Lokhorst, and A. Jauch, Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p, Blood, vol.119, issue.4, pp.940-948, 2012.
DOI : 10.1182/blood-2011-09-379164

R. Fonseca, B. Barlogie, and R. Bataille, Genetics and Cytogenetics of Multiple Myeloma: A Workshop Report, Cancer Research, vol.64, issue.4, pp.1546-1558, 2004.
DOI : 10.1158/0008-5472.CAN-03-2876

H. Avet-loiseau, M. Attal, and P. Moreau, Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myelome, Blood, vol.109, issue.8, pp.3489-3495, 2007.
DOI : 10.1182/blood-2006-08-040410

D. Hose, J. Moreaux, and T. Meissner, Induction of angiogenesis by normal and malignant plasma cells, Blood, vol.114, issue.1, pp.128-143, 2009.
DOI : 10.1182/blood-2008-10-184226

URL : https://hal.archives-ouvertes.fr/inserm-00401390

D. Hose, T. Rè-me, and T. Meissner, Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma, Blood, vol.113, issue.18, pp.4331-4340, 2009.
DOI : 10.1182/blood-2008-09-178350

URL : https://hal.archives-ouvertes.fr/inserm-00368414

A. Seckinger, T. Meissner, and J. Moreaux, Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis, Oncogene, vol.83, issue.44, pp.3866-3879, 2009.
DOI : 10.1182/blood.V99.5.1745

URL : https://hal.archives-ouvertes.fr/inserm-00437705

J. Caers, D. Hose, and I. Kuipers, Thymosin ??4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma, Haematologica, vol.95, issue.1, pp.163-167, 2010.
DOI : 10.3324/haematol.2009.006411

URL : https://hal.archives-ouvertes.fr/inserm-00453267

F. Zhan, Y. Huang, and S. Colla, The molecular classification of multiple myeloma, Blood, vol.108, issue.6, pp.2020-2028, 2006.
DOI : 10.1182/blood-2005-11-013458

P. Bergsagel and W. Kuehl, Molecular Pathogenesis and a Consequent Classification of Multiple Myeloma, Journal of Clinical Oncology, vol.23, issue.26, pp.6333-6338, 2005.
DOI : 10.1200/JCO.2005.05.021

K. Mahtouk, D. Hose, and P. Raynaud, Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma, Blood, vol.109, issue.11, pp.4914-4923, 2007.
DOI : 10.1182/blood-2006-08-043232

URL : https://hal.archives-ouvertes.fr/inserm-00136105

K. Mahtouk, D. Hose, and T. Rè-me, Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells, Oncogene, vol.83, issue.21, pp.3512-3524, 2005.
DOI : 10.1038/sj.onc.1208536

URL : https://hal.archives-ouvertes.fr/inserm-00130206

B. Klein, A. Seckinger, T. Moehler, and D. Hose, Molecular Pathogenesis of Multiple Myeloma: Chromosomal Aberrations, Changes in Gene Expression, Cytokine Networks, and the Bone Marrow Microenvironment, Recent Results Cancer Res, vol.183, pp.39-86, 2011.
DOI : 10.1007/978-3-540-85772-3_3

N. Munshi, T. Hideshima, and D. Carrasco, Identification of genes modulated in multiple myeloma using genetically identical twin samples, Blood, vol.103, issue.5, pp.1799-1806, 2004.
DOI : 10.1182/blood-2003-02-0402

H. Bao, M. Jiang, M. Zhu, F. Sheng, J. Ruan et al., Overexpression of Annexin II affects the proliferation, apoptosis, invasion and production of proangiogenic factors in multiple myeloma, International Journal of Hematology, vol.102, issue.1, pp.177-185, 2009.
DOI : 10.1007/s12185-009-0356-8

G. Lu, H. Maeda, and S. Reddy, Cloning and Characterization of the Annexin II Receptor on Human Marrow Stromal Cells, Journal of Biological Chemistry, vol.281, issue.41, pp.30542-30550, 2006.
DOI : 10.1074/jbc.M607072200

D. Souza, S. Kurihara, N. Shiozawa, and Y. , Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment, Blood, vol.119, issue.8, pp.1888-1896, 2012.
DOI : 10.1182/blood-2011-11-393348

M. Sharma and M. Sharma, The Role of Annexin II in Angiogenesis and Tumor Progression: A Potential Therapeutic Target, Current Pharmaceutical Design, vol.13, issue.35, pp.3568-3575, 2007.
DOI : 10.2174/138161207782794167

Q. Ling, A. Jacovina, and A. Deora, Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo, Journal of Clinical Investigation, vol.113, issue.1, pp.38-48, 2004.
DOI : 10.1172/JCI19684

J. Gillette and S. Nielsen-preiss, The role of annexin 2 in osteoblastic mineralization, Journal of Cell Science, vol.117, issue.3, pp.441-449, 2004.
DOI : 10.1242/jcs.00909

C. Menaa, R. Devlin, S. Reddy, Y. Gazitt, S. Choi et al., Annexin II increases osteoclast formation by stimulating the proliferation of osteoclast precursors in human marrow cultures, Journal of Clinical Investigation, vol.103, issue.11, pp.1605-1613, 1999.
DOI : 10.1172/JCI6374

S. Takahashi, S. Reddy, and J. Chirgwin, Cloning and identification of annexin II as an autocrine/paracrine factor that increases osteoclast

J. Corre, K. Mahtouk, and M. Attal, Bone marrow mesenchymal stem cells are abnormal in multiple myeloma, Leukemia, vol.63, issue.5, pp.1079-1088, 2007.
DOI : 10.1038/sj.leu.2404621

URL : https://hal.archives-ouvertes.fr/inserm-00270565

G. Fuhler, M. Baanstra, and D. Chesik, Bone marrow stromal cell interaction reduces Syndecan-1 expression and induces kinomic changes in myeloma cells, Experimental Cell Research, vol.316, issue.11, pp.1816-1828, 2010.
DOI : 10.1016/j.yexcr.2010.03.013

W. Wagner, F. Wein, and A. Seckinger, Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood, Experimental Hematology, vol.33, issue.11, pp.1402-1416, 2005.
DOI : 10.1016/j.exphem.2005.07.003

S. Wuilleme, N. Robillard, and L. Lodé, Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma, Leukemia, vol.19, issue.2, pp.275-278, 2005.
DOI : 10.1038/sj.leu.2403586

Z. Wu, R. Irizarry, R. Gentleman, F. Martinez-murillo, and F. Spencer, A Model-Based Background Adjustment for Oligonucleotide Expression Arrays, Journal of the American Statistical Association, vol.99, issue.468, pp.909-917, 2004.
DOI : 10.1198/016214504000000683

W. Johnson, C. Li, and A. Rabinovic, Adjusting batch effects in microarray expression data using empirical Bayes methods, Biostatistics, vol.8, issue.1, pp.118-127, 2007.
DOI : 10.1093/biostatistics/kxj037

P. Warren, D. Taylor, P. Martini, J. Jackson, and J. Bienkowska, PANP - a New Method of Gene Detection on Oligonucleotide Expression Arrays, 2007 IEEE 7th International Symposium on BioInformatics and BioEngineering, pp.108-115, 2007.
DOI : 10.1109/BIBE.2007.4375552

G. Smyth, Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments, Statistical Applications in Genetics and Molecular Biology, vol.3, issue.1, p.3, 2004.
DOI : 10.2202/1544-6115.1027

Y. Benjamini and Y. Hochberg, Controlling the false discovery: a practical and powerful approach to multiple testing, J R Stat Soc Series B, vol.57, pp.289-300, 1995.

R. Gentleman, V. Carey, and D. Bates, Bioconductor: open software development for computational biology and bioinformatics, Genome Biology, vol.5, issue.10, p.80, 2004.
DOI : 10.1186/gb-2004-5-10-r80

E. Tian, F. Zhan, and R. Walker, The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma, New England Journal of Medicine, vol.349, issue.26, pp.2483-2494, 2003.
DOI : 10.1056/NEJMoa030847

A. Sprynski, D. Hose, and L. Caillot, The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor, Blood, vol.113, issue.19, pp.4614-4626, 2009.
DOI : 10.1182/blood-2008-07-170464

URL : https://hal.archives-ouvertes.fr/inserm-00367812

I. Esposito, R. Penzel, and M. Chaib-harrireche, Tenascin C and annexin II expression in the process of pancreatic carcinogenesis, The Journal of Pathology, vol.22, issue.5, pp.673-685, 2006.
DOI : 10.1002/path.1935

M. Sharma, L. Koltowski, R. Ownbey, G. Tuszynski, and M. Sharma, Angiogenesis-associated protein annexin II in breast cancer: Selective expression in invasive breast cancer and contribution to tumor invasion and progression, Experimental and Molecular Pathology, vol.81, issue.2, pp.146-156, 2006.
DOI : 10.1016/j.yexmp.2006.03.003

J. Liu, J. Shen, and A. Tanzillo-swarts, Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration, Oncogene, vol.22, issue.10, pp.1475-1485, 2003.
DOI : 10.1038/sj.onc.1206196

Y. Shiozawa, A. Havens, and Y. Jung, Annexin II/Annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer, Journal of Cellular Biochemistry, vol.278, issue.Pt 3, pp.370-380, 2008.
DOI : 10.1002/jcb.21835