L. Vandenberg, Exposure to Environmentally Relevant Doses of the Xenoestrogen Bisphenol-A Alters Development of the Fetal Mouse Mammary Gland, Endocrinology, vol.148, issue.1, pp.116-127, 2007.
DOI : 10.1210/en.2006-0561

W. Dekant and W. Volkel, Human exposure to bisphenol A by biomonitoring: Methods, results and assessment of environmental exposures, Toxicology and Applied Pharmacology, vol.228, issue.1, pp.114-134, 2008.
DOI : 10.1016/j.taap.2007.12.008

L. Vandenberg, Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A, Environmental Health Perspectives, vol.118, issue.8, pp.1055-1070, 2010.
DOI : 10.1289/ehp.0901716

D. Zalko, C. Jacques, H. Duplan, S. Bruel, and E. Perdu, Viable skin efficiently absorbs and metabolizes bisphenol A, Chemosphere, vol.82, issue.3, pp.424-430, 2011.
DOI : 10.1016/j.chemosphere.2010.09.058

D. Crain, An ecological assessment of bisphenol-A: Evidence from comparative biology, Reproductive Toxicology, vol.24, issue.2, pp.225-239, 2007.
DOI : 10.1016/j.reprotox.2007.05.008

C. Richter, In vivo effects of bisphenol A in laboratory rodent studies, Reproductive Toxicology, vol.24, issue.2, pp.199-224, 2007.
DOI : 10.1016/j.reprotox.2007.06.004

E. Chung, M. Genco, L. Megrelis, and J. Ruderman, Effects of bisphenol A and triclocarban on brain-specific expression of aromatase in early zebrafish embryos, Proceedings of the National Academy of Sciences, vol.108, issue.43, pp.17732-17737, 2011.
DOI : 10.1073/pnas.1115187108

R. Tyl, Two-Generation Reproductive Toxicity Study of Dietary Bisphenol A in CD-1 (Swiss) Mice, Toxicological Sciences, vol.104, issue.2, pp.362-384, 2008.
DOI : 10.1093/toxsci/kfn084

B. Rubin and A. Soto, Bisphenol A: Perinatal exposure and body weight, Molecular and Cellular Endocrinology, vol.304, issue.1-2, pp.55-62, 2009.
DOI : 10.1016/j.mce.2009.02.023

R. Newbold, W. Jefferson, and . Padilla, Prenatal exposure to bisphenol a at environmentally relevant doses adversely affects the murine female reproductive tract later in life An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment, Environ Health Perspect Environ Health Perspect, vol.117, issue.1138, pp.926-933, 2005.

L. Vandenberg, M. Maffini, C. Sonnenschein, B. Rubin, and A. Soto, Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption, Endocrine Reviews, vol.30, issue.1, pp.75-95, 2009.
DOI : 10.1210/er.2008-0021

G. Kuiper, Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta, Endocrinology, vol.138, issue.3, pp.863-870, 1997.

S. Soriano, Rapid Insulinotropic Action of Low Doses of Bisphenol-A on Mouse and Human Islets of Langerhans: Role of Estrogen Receptor ??, PLoS ONE, vol.117, issue.2, p.31109, 2012.
DOI : 10.1371/journal.pone.0031109.s001

W. Mnif, Estrogens and antiestrogens activate hPXR, Toxicology Letters, vol.170, issue.1, pp.19-29, 2007.
DOI : 10.1016/j.toxlet.2006.11.016

Y. Sui, Bisphenol A and Its Analogues Activate Human Pregnane X Receptor, Environmental Health Perspectives, vol.120, issue.3, pp.399-405, 2012.
DOI : 10.1289/ehp.1104426

URL : http://doi.org/10.1289/ehp.1104426

H. Okada, Direct Evidence Revealing Structural Elements Essential for the High Binding Ability of Bisphenol A to Human Estrogen-Related Receptor-??, Environmental Health Perspectives, vol.116, issue.1, pp.32-38, 2008.
DOI : 10.1289/ehp.10587

A. Riu, Peroxisome Proliferator-Activated Receptor ?? Is a Target for Halogenated Analogs of Bisphenol A, Environmental Health Perspectives, vol.119, issue.9, pp.1227-1232, 2011.
DOI : 10.1289/ehp.1003328

A. Riu, Characterization of Novel Ligands of ER??, Er??, and PPAR??: The Case of Halogenated Bisphenol A and Their Conjugated Metabolites, Toxicological Sciences, vol.122, issue.2, pp.372-382, 2011.
DOI : 10.1093/toxsci/kfr132

F. Paris, Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit ?? and ?? estrogen activities and antiandrogen activity in reporter cell lines, Molecular and Cellular Endocrinology, vol.193, issue.1-2, pp.43-49, 2002.
DOI : 10.1016/S0303-7207(02)00094-1

J. Fini, Parallel Biotransformation of Tetrabromobisphenol A in Xenopus laevis and Mammals: Xenopus as a Model for Endocrine Perturbation Studies, Toxicological Sciences, vol.125, issue.2, pp.359-367, 2012.
DOI : 10.1093/toxsci/kfr312

K. Moriyama, Thyroid Hormone Action Is Disrupted by Bisphenol A as an Antagonist, The Journal of Clinical Endocrinology & Metabolism, vol.87, issue.11, pp.5185-5190, 2002.
DOI : 10.1210/jc.2002-020209

E. Levin, Minireview: Extranuclear Steroid Receptors: Roles in Modulation of Cell Functions, Molecular Endocrinology, vol.25, issue.3, pp.377-384, 2011.
DOI : 10.1210/me.2010-0284

H. Gronemeyer, J. Gustafsson, and V. Laudet, Principles for modulation of the nuclear receptor superfamily, Nature Reviews Drug Discovery, vol.97, issue.11, pp.950-964, 2004.
DOI : 10.1242/jcs.00247

N. Heldring, Estrogen Receptors: How Do They Signal and What Are Their Targets, Physiological Reviews, vol.87, issue.3, pp.905-931, 2007.
DOI : 10.1152/physrev.00026.2006

V. Perissi and M. Rosenfeld, Controlling nuclear receptors: the circular logic of cofactor cycles, Nature Reviews Molecular Cell Biology, vol.12, issue.7, pp.542-554, 2005.
DOI : 10.1038/nature01550

A. Benecke, P. Chambon, and H. Gronemeyer, Synergy between estrogen receptor ?? activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2, EMBO reports, vol.12, issue.2, pp.151-157, 2000.
DOI : 10.1093/embo-reports/kvd028

R. Metivier, G. Penot, G. Flouriot, and F. Pakdel, Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein- 1: requirement for the AF-1 alpha-helical core and for a direct interaction between the Nand C-terminal domains, Mol Endocrinol, vol.15, issue.11, pp.1953-1970, 2001.

V. Nahoum and W. Bourguet, Androgen and estrogen receptors: Potential of crystallography in the fight against cancer, The International Journal of Biochemistry & Cell Biology, vol.39, issue.7-8, pp.1280-1287, 2007.
DOI : 10.1016/j.biocel.2007.01.001

A. Pike, Lessons learnt from structural studies of the oestrogen receptor, Best Practice & Research Clinical Endocrinology & Metabolism, vol.20, issue.1, pp.1-14, 2006.
DOI : 10.1016/j.beem.2005.09.002

P. Huang, V. Chandra, and F. Rastinejad, Structural Overview of the Nuclear Receptor Superfamily: Insights into Physiology and Therapeutics, Annual Review of Physiology, vol.72, issue.1, pp.247-272, 2010.
DOI : 10.1146/annurev-physiol-021909-135917

J. Molina-molina, Profiling of benzophenone derivatives using fish and human estrogen receptor-specific in vitro bioassays, Toxicology and Applied Pharmacology, vol.232, issue.3, pp.384-395, 2008.
DOI : 10.1016/j.taap.2008.07.017

URL : https://hal.archives-ouvertes.fr/inserm-00319498

V. Nahoum, Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function, Proceedings of the National Academy of Sciences, vol.104, issue.44, pp.17323-17328, 2007.
DOI : 10.1073/pnas.0705356104

URL : https://hal.archives-ouvertes.fr/hal-00188372

K. Nettles, NF??B selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses, Nature Chemical Biology, vol.50, issue.4, pp.241-247, 2008.
DOI : 10.1038/nchembio.76

J. Bruning, Coupling of receptor conformation and ligand orientation determine graded activity, Nature Chemical Biology, vol.62, issue.11, pp.837-843, 2010.
DOI : 10.1038/nchembio.451

J. Osz, Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors, Proceedings of the National Academy of Sciences, vol.109, issue.10, pp.588-594
DOI : 10.1073/pnas.1118192109

L. Nagy and J. Schwabe, Mechanism of the nuclear receptor molecular switch, Trends in Biochemical Sciences, vol.29, issue.6, pp.317-324, 2004.
DOI : 10.1016/j.tibs.2004.04.006

A. Gee and J. Katzenellenbogen, Probing Conformational Changes in the Estrogen Receptor: Evidence for a Partially Unfolded Intermediate Facilitating Ligand Binding and Release, Molecular Endocrinology, vol.15, issue.3, pp.421-428, 2001.
DOI : 10.1210/mend.15.3.0602

J. Pons and G. Labesse, @TOME-2: a new pipeline for comparative modeling of protein-ligand complexes, Nucleic Acids Research, vol.37, issue.Web Server, pp.485-491, 2009.
DOI : 10.1093/nar/gkp368

O. Korb, T. Stutzle, and T. Exner, Empirical Scoring Functions for Advanced Protein???Ligand Docking with PLANTS, Journal of Chemical Information and Modeling, vol.49, issue.1, pp.84-96, 2009.
DOI : 10.1021/ci800298z

G. Neudert and G. Klebe, : A Knowledge-Based Scoring Function for the Assessment of Protein???Ligand Complexes, Journal of Chemical Information and Modeling, vol.51, issue.10, pp.2731-2745, 2011.
DOI : 10.1021/ci200274q

M. Abad, Structural determination of estrogen-related receptor ?? in the presence of phenol derivative compounds, The Journal of Steroid Biochemistry and Molecular Biology, vol.108, issue.1-2, pp.44-54, 2008.
DOI : 10.1016/j.jsbmb.2007.06.006

A. Matsushima, Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERR??, Journal of Biochemistry, vol.142, issue.4, pp.517-524, 2007.
DOI : 10.1093/jb/mvm158

E. Perez-santin, Modulating retinoid X receptor with a series of (E)-3-[4-hydroxy- 3-(3-alkoxy-5-tetrahydronaphtha len-2-yl)phenyl]acrylic acids and their 4-alkoxy isomers, J Med Chem, vol.5867, issue.5210, pp.8-53150, 2009.