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Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells.

Abstract : Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNγ-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antigens to T lymphocytes both in vitro and in vivo.
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https://www.hal.inserm.fr/inserm-00723079
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Submitted on : Sunday, June 30, 2013 - 7:00:16 AM
Last modification on : Friday, June 8, 2018 - 2:50:12 PM
Long-term archiving on: : Tuesday, October 1, 2013 - 2:25:08 AM

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2012ONCOIMM0017.pdf
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  • HAL Id : inserm-00723079, version 1
  • PUBMED : 22754789

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Nicolas Larmonier, Bernard Bonnotte, Emmanuel Katsanis. Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells.. OncoImmunology, Taylor & Francis, 2012, 1 (4), pp.566-568. ⟨inserm-00723079⟩

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