Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells.
Abstract
Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNγ-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antigens to T lymphocytes both in vitro and in vivo.
Domains
Immunology
Origin : Publisher files allowed on an open archive
Loading...