The chemoinvasion assay: a method to assess tumor and endothelial cell invasion and its modulation, Nature Protocols, vol.2, issue.3, pp.504-511, 2007. ,
DOI : 10.1038/nprot.2006.466
NFATc2-Mediated Repression of Cyclin-Dependent Kinase 4 Expression, Molecular Cell, vol.10, issue.5, pp.1071-1081, 2002. ,
DOI : 10.1016/S1097-2765(02)00701-3
Inflammation and cancer: back to Virchow?, The Lancet, vol.357, issue.9255, pp.357539-545, 2001. ,
DOI : 10.1016/S0140-6736(00)04046-0
Cloning and expression of human neutrophil lipocalin cDNA derived from bone marrow and ovarian cancer cells, FEBS Letters, vol.326, issue.3, pp.255-671, 1995. ,
DOI : 10.1016/0014-5793(94)01303-I
Overexpression of c-myc in pancreatic cancer caused by ectopic 673 activation of NFATc1 and the Ca2+/calcineurin signaling pathway, The EMBO Journal, vol.674, issue.15, pp.253714-3724, 2006. ,
Integrin alpha6beta4 promotes expression of 676 autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells, Oncogene, vol.24, issue.32, pp.6775125-5130, 2005. ,
Autoregulation of NFATc1/A Expression Facilitates Effector T Cells to Escape from Rapid Apoptosis, Immunity, vol.16, issue.6, pp.881-895, 2002. ,
DOI : 10.1016/S1074-7613(02)00329-1
Antibodies to TWEAK receptor inhibit human tumor growth 681 through dual mechanisms Clinical cancer research : an official journal of the American 682 Association for, Cancer Research, vol.16, issue.2, pp.497-508, 2010. ,
TWEAK promotes ovarian cancer cell metastasis via NF-??B pathway activation and VEGF expression, Cancer Letters, vol.283, issue.2, pp.159-167, 2009. ,
DOI : 10.1016/j.canlet.2009.03.036
Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt- 688 5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells, Molecular and cellular biology, vol.26, issue.16, pp.6024-6036, 2006. ,
The lipocalin protein family: structure and function The Biochemical 691 journal 318, pp.1-14, 1996. ,
Breast cancer-specific mutations in CK1?? inhibit Wnt/??-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration, Breast Cancer Research, vol.7, issue.3, pp.30-695, 2010. ,
DOI : 10.1038/ncb1271
NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene, Oncogene, vol.48, issue.15, pp.2292-2301, 2010. ,
DOI : 10.1002/pmic.200200679
Proteolytic and non-proteolytic migration of tumour 698 cells and leucocytes, Biochemical Society symposium, issue.70, pp.277-285, 2003. ,
Identification of a neutrophil gelatinase-associated lipocalin mRNA in human pancreatic cancers using a modified signal sequence trap method, Cancer Letters, vol.122, issue.1-2, pp.209-214, 1998. ,
DOI : 10.1016/S0304-3835(97)00391-1
Dual role of the ddx5/ddx17 RNA helicases in the 704 control of the pro-migratory NFAT5 transcription factor, Oncogene, p.618, 2011. ,
A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus, Blood, vol.106, issue.10, pp.3546-3552, 2005. ,
DOI : 10.1182/blood-2005-02-0493
Expression of Neutrophil Gelatinase-associated Lipocalin Regulates Epithelial Morphogenesis in Vitro, Journal of Biological Chemistry, vol.280, issue.9, pp.7875-713, 2005. ,
DOI : 10.1074/jbc.M413192200
FRNK blocks v-Src-stimulated invasion and experimental metastases 716 without effects on cell motility or growth, The EMBO Journal, vol.21, issue.23, pp.6289-6302, 2002. ,
Genomic DNA-chip hybridization reveals a higher 718 incidence of genomic amplifications in pancreatic cancer than conventional comparative 719 genomic hybridization and leads to the identification of novel candidate genes, Cancer Research, vol.720, issue.6413, pp.4428-4433, 2004. ,
Differential regulation of cell motility and invasion by FAK, The Journal of Cell Biology, vol.112, issue.5, pp.753-767, 2003. ,
DOI : 10.1074/jbc.M010190200
Regulation of In Situ to Invasive Breast Carcinoma Transition, Cancer Cell, vol.13, issue.5, pp.394-406, 2008. ,
DOI : 10.1016/j.ccr.2008.03.007
An Epigenetic Switch Involving NF-??B, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation, Cell, vol.139, issue.4, pp.693-706, 2009. ,
DOI : 10.1016/j.cell.2009.10.014
Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial???mesenchymal transition, The Journal of Cell Biology, vol.267, issue.6, pp.1023-1034, 2005. ,
DOI : 10.1126/science.286.5445.1741
The role of NFAT transcription factors in integrin-mediated carcinoma invasion, Nature Cell Biology, vol.4, issue.7, pp.540-544, 2002. ,
DOI : 10.1038/ncb816
URL : https://hal.archives-ouvertes.fr/inserm-00000023
TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage, Biochemical and Biophysical Research Communications, vol.331, issue.2, pp.384-390, 2005. ,
DOI : 10.1016/j.bbrc.2005.03.176
Temporal and quantitative regulation of mitogen-activated protein kinase (MAPK) modulates cell motility and invasion, Oncogene, vol.20, issue.31, pp.4209-4218, 2001. ,
DOI : 10.1038/sj.onc.1204541
NFATc3 deficiency may contribute to the development of mammary gland adenocarcinoma in aging female mice, Molecular Carcinogenesis, vol.4, issue.3, pp.219-222, 2005. ,
DOI : 10.1002/mc.20136
Lipocalin 2 is required for BCR-ABL-induced tumorigenesis, Oncogene, vol.60, issue.47, pp.6110-6119, 2008. ,
DOI : 10.1038/onc.2008.209
NFAT5, a 746 constitutively nuclear NFAT protein that does not cooperate with Fos and Jun, Proceedings of the National Academy of Sciences of the United States of America, vol.96, issue.13, pp.7487214-7219, 1999. ,
TWEAK Attenuates the Transition from Innate to Adaptive Immunity, Cell, vol.123, issue.5, pp.931-944, 2005. ,
DOI : 10.1016/j.cell.2005.09.022
NFAT proteins: emerging roles in cancer progression, Nature Reviews Cancer, vol.3, issue.11, pp.810-820, 2009. ,
DOI : 10.1038/nrc2735
The Mitogen-inducible Fn14 Gene Encodes a Type I Transmembrane Protein that Modulates Fibroblast Adhesion and Migration, Journal of Biological Chemistry, vol.274, issue.46, pp.33166-33176, 1999. ,
DOI : 10.1074/jbc.274.46.33166
Tweak induces mammary epithelial branching morphogenesis, Oncogene, vol.21, issue.16, pp.2613-2624, 2005. ,
DOI : 10.1038/sj.onc.1208208
Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis, International Journal of Cancer, vol.112, issue.1, pp.100-112, 2004. ,
DOI : 10.1002/ijc.20376
A constitutively active NFATc1 mutant induces a 762 transformed phenotype in 3T3-L1 fibroblasts, The Journal of biological chemistry, vol.278, pp.76317246-17254, 2003. ,
Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases., Gut, vol.38, issue.3, pp.414-420, 1996. ,
DOI : 10.1136/gut.38.3.414
Expression of TWEAK in normal human skin, dermatitis and epidermal 768 neoplasms: association with proliferation and differentiation of keratinocytes, Journal of 769 cutaneous pathology, vol.38, issue.10, pp.780-789, 2011. ,
Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients, Journal of Clinical Oncology, vol.27, issue.21, pp.3437-3444, 2009. ,
DOI : 10.1200/JCO.2008.18.9068
Effects of Mouse and Human Lipocalin Homologues 24p3/lcn2 and Neutrophil Gelatinase???Associated Lipocalin on Gastrointestinal Mucosal Integrity and Repair, Gastroenterology, vol.131, issue.3, pp.809-817, 2006. ,
DOI : 10.1053/j.gastro.2006.05.051
TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the 778 absence of Fn14/TweakR. Evidence for a second TWEAK receptor, Journal of 779 Biological Chemistry, vol.777, issue.27834, pp.32317-32323, 2003. ,
Inhibitory function of two 781 NFAT family members in lymphoid homeostasis and Th2 development, Immunity, vol.9, issue.5, pp.782627-635, 1998. ,
Dual Roles for NFAT Transcription Factor Genes as Oncogenes and Tumor Suppressors, Molecular and Cellular Biology, vol.28, issue.23, pp.7168-7181, 2008. ,
DOI : 10.1128/MCB.00256-08
Identification of a putative regulator of early T cell activation genes, Science, vol.241, issue.4862, pp.202-205, 1988. ,
DOI : 10.1126/science.3260404
Lipocalin 2 promotes lung metastasis of murine breast cancer cells, Journal of Experimental & Clinical Cancer Research, vol.27, issue.1, pp.83-790, 2008. ,
DOI : 10.1186/1756-9966-27-83
Heterogeneous expression of the lipocalin NGAL in primary breast cancers, International Journal of Cancer, vol.28, issue.6, pp.565-792, 1998. ,
DOI : 10.1002/(SICI)1097-0215(19981218)79:6<565::AID-IJC3>3.0.CO;2-F
Increased Fibroblast Growth Factor-Inducible 14 Expression Levels Promote Glioma Cell Invasion via Rac1 and Nuclear Factor-??B and Correlate with Poor Patient Outcome, Cancer Research, vol.66, issue.19, pp.9535-9542, 2006. ,
DOI : 10.1158/0008-5472.CAN-06-0418
Pro-inflammatory cytokines TNF-related weak inducer of 797 apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase 798 (MAPK)-dependent expression of sclerostin in human osteoblasts, Journal of bone and 799 mineral research : the official journal of the American Society for Bone and Mineral 800 Research, pp.1434-1449, 2009. ,
A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis, Immunity, vol.15, issue.5, pp.837-846, 2001. ,
DOI : 10.1016/S1074-7613(01)00232-1
The Fibroblast Growth Factor-Inducible 14 Receptor Is Highly Expressed in HER2-Positive Breast Tumors and Regulates Breast Cancer Cell Invasive Capacity, Molecular Cancer Research, vol.6, issue.5, pp.725-734, 2008. ,
DOI : 10.1158/1541-7786.MCR-08-0005
The TWEAK???Fn14 cytokine???receptor axis: discovery, biology and therapeutic targeting, Nature Reviews Drug Discovery, vol.109, issue.5, pp.411-425, 2008. ,
DOI : 10.1002/jnr.21443
Opposing roles for calcineurin and ATF3 in squamous skin cancer, Nature, vol.289, issue.7296, pp.368-372, 2010. ,
DOI : 10.1073/pnas.85.17.6389
An Enhanced Immune Response in Mice Lacking the Transcription Factor NFAT1, Science, vol.272, issue.5263, pp.892-895, 1996. ,
DOI : 10.1126/science.272.5263.892
Lipocalin 2 promotes breast cancer progression, Proceedings of the 813 National Academy of Sciences of the United States of America, pp.3913-3918, 2009. ,
DOI : 10.1073/pnas.0810617106
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656179
NFAT Induces Breast Cancer Cell Invasion by Promoting the Induction of Cyclooxygenase-2, Journal of Biological Chemistry, vol.281, issue.18, pp.12210-816, 2006. ,
DOI : 10.1074/jbc.M600184200
Akt Blocks Breast Cancer Cell Motility and Invasion through the Transcription Factor NFAT, Molecular Cell, vol.20, issue.4, pp.539-550, 2005. ,
DOI : 10.1016/j.molcel.2005.10.033
URL : https://hal.archives-ouvertes.fr/inserm-00000020