Unscrambling hepatitis C virus???host interactions, Nature, vol.68, issue.7053, pp.930-932, 2005. ,
DOI : 10.1053/jhep.2001.24371
Hepatitis C treatment update, The American Journal of Medicine, vol.117, issue.5, pp.344-352, 2004. ,
DOI : 10.1016/j.amjmed.2004.03.024
Structural and mechanistic insights into hepatitis C viral translation initiation, Nature Reviews Microbiology, vol.265, issue.1, pp.29-38, 2007. ,
DOI : 10.1038/nrm1618
The Pathway of HCV IRES-Mediated Translation Initiation, Cell, vol.119, issue.3, pp.369-380, 2004. ,
DOI : 10.1016/j.cell.2004.09.038
Comparative Analysis of Translation Efficiencies of Hepatitis C Virus 5' Untranslated Regions among Intraindividual Quasispecies Present in Chronic Infection: Opposite Behaviors Depending on Cell Type, Journal of Virology, vol.74, issue.22, pp.10827-10833, 2000. ,
DOI : 10.1128/JVI.74.22.10827-10833.2000
Sequence analysis of the 5' noncoding region of hepatitis C virus., Proc. Natl Acad. Sci. USA, pp.4942-4946, 1992. ,
DOI : 10.1073/pnas.89.11.4942
In vivo translational efficiency of different hepatitis C virus 5???-UTRs, FEBS Letters, vol.2, issue.2-3, pp.275-280, 1997. ,
DOI : 10.1016/S0014-5793(97)00715-1
Natural Variation in Translational Activities of the 5??? Nontranslated RNAs of Genotypes 1a and 1b Hepatitis C Virus: Evidence for a Long Range RNA-RNA Interaction Outside of the Internal Ribosomal Entry Segment, J. Virol, vol.73, pp.4941-4951, 1999. ,
DOI : 10.1007/978-4-431-68488-6_5
Secondary structure of the 5??? nontranslated regions of hepatitis C virus and pestivirus genomic RNAs, Nucleic Acids Research, vol.20, issue.19, pp.5041-5045, 1992. ,
DOI : 10.1093/nar/20.19.5041
Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function, Nat. Struct. Biol, vol.7, pp.1105-1110, 2000. ,
Structure of HCV IRES domain II determined by NMR, Nature Structural Biology, vol.10, issue.12, pp.1033-1038, 2003. ,
DOI : 10.1038/nsb1004
Functional Architecture of HCV IRES Domain???II Stabilized by Divalent Metal Ions in the Crystal and in Solution, Angewandte Chemie International Edition, vol.39, issue.1-2, pp.226-229, 2006. ,
DOI : 10.1002/anie.200603807
An Enzymatic Footprinting Analysis of the Interaction of 40S Ribosomal Subunits with the Internal Ribosomal Entry Site of Hepatitis C Virus, Journal of Virology, vol.74, issue.14, pp.6242-6250, 2000. ,
DOI : 10.1128/JVI.74.14.6242-6250.2000
Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40S Ribosomal Subunit, Science, vol.291, issue.5510, pp.1959-1962, 2001. ,
DOI : 10.1126/science.1058409
Structure of the Hepatitis C Virus IRES Bound to the Human 80S Ribosome: Remodeling of the HCV IRES, Structure, vol.13, issue.11, pp.1695-1706, 2005. ,
DOI : 10.1016/j.str.2005.08.008
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis, Science, vol.310, issue.5753, pp.310-1513, 2005. ,
DOI : 10.1126/science.1118977
Targeting RNA with Small-Molecule Drugs:?? Therapeutic Promise and Chemical Challenges, Accounts of Chemical Research, vol.34, issue.10, pp.836-843, 2001. ,
DOI : 10.1021/ar000118k
Challenges and successes in developing new therapies for hepatitis C, Nature, vol.40, issue.7053, pp.953-960, 2005. ,
DOI : 10.1016/j.cbpa.2004.10.007
Oligonucleotide-based Strategies to Inhibit Human Hepatitis C Virus, Oligonucleotides, vol.13, issue.6, pp.539-548, 2003. ,
DOI : 10.1089/154545703322860834
A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId, Nucleic Acids Research, vol.33, issue.2, pp.683-692, 2005. ,
DOI : 10.1093/nar/gki215
Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation, Nucleic Acids Research, vol.31, issue.2, pp.734-742, 2003. ,
DOI : 10.1093/nar/gkg139
RNA Aptamers Targeted to Domain II of Hepatitis C Virus IRES That Bind to Its Apical Loop Region, Journal of Biochemistry, vol.133, issue.3, pp.263-270, 2003. ,
DOI : 10.1093/jb/mvg036
Determinants of apical loop???internal loop RNA???RNA interactions involving the HCV IRES, Biochemical and Biophysical Research Communications, vol.322, issue.3, pp.820-826, 2004. ,
DOI : 10.1016/j.bbrc.2004.07.185
Cationic phosphoramidate ??-oligonucleotides efficiently target single-stranded DNA and RNA and inhibit hepatitis C virus IRES-mediated translation, Nucleic Acids Research, vol.31, issue.18, pp.5282-5290, 2003. ,
DOI : 10.1093/nar/gkg733
URL : http://doi.org/10.1093/nar/gkg733
Antisense oligonucleotide inhibition of hepatitis C Virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant, Antimicrob. Agents Chemother, vol.43, pp.347-353, 1999. ,
Small interfering RNA targeted to stem-loop II of the 5 0 untranslated region effectively inhibits expression of six HCV genotypes, Virology Journal, vol.3, issue.1, p.100, 2006. ,
DOI : 10.1186/1743-422X-3-100
Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs), Nucleic Acids Research, vol.32, issue.13, pp.3792-3798, 2004. ,
DOI : 10.1093/nar/gkh706
Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes, J. Virol, vol.70, pp.5203-5212, 1996. ,
A phase I trial of an antisense inhibitor of hepatitis C virus (ISIS 14803), administered to chronic hepatitis C patients, Journal of Hepatology, vol.44, issue.1, pp.88-96, 2006. ,
DOI : 10.1016/j.jhep.2005.09.009
Artificial ribonucleases, Org. Biomol. Chem., vol.35, issue.1, pp.15-25, 2006. ,
DOI : 10.1039/B509022A
Inorganic Mimics of Ribonucleases and Ribozymes:?? From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs, Chemical Reviews, vol.98, issue.3, pp.939-960, 1998. ,
DOI : 10.1021/cr960422k
Artificial ribonucleases: synthesis and RNA cleaving properties of cationic conjugates bearing imidazole residues, Tetrahedron, vol.55, issue.2, pp.503-512, 1999. ,
DOI : 10.1016/S0040-4020(98)01048-5
Site-specific cleavage of tRNA by imidazole and/or primary amine groups bound at the 5???-end of oligodeoxyribonucleotides, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1379, issue.2, pp.1379-217, 1998. ,
DOI : 10.1016/S0304-4165(97)00101-3
Sequence-specific artificial ribonucleases. I. Bis-imidazole-containing oligonucleotide conjugates prepared using precursor-based strategy, Nucleic Acids Research, vol.32, issue.13, pp.3887-3897, 2004. ,
DOI : 10.1093/nar/gkh702
Polyamine derivatives as selective RNaseA mimics, Nucleic Acids Research, vol.32, issue.1, pp.151-157, 2004. ,
DOI : 10.1093/nar/gkh157
URL : https://hal.archives-ouvertes.fr/inserm-00715063
N??-Urocanylhistamine: A Natural Histamine Derivative, Molecules, vol.7, issue.11, pp.813-816, 2002. ,
DOI : 10.3390/71100813
Preparation and nuclease activity of hybrid "metallotris(methylpyridinium)porphyrin oligonucleotide" molecules having a 3'-loop for protection against 3'-exonucleases, Bioconjugate Chemistry, vol.6, issue.4, pp.466-472, 1995. ,
DOI : 10.1021/bc00034a017
Image processing with ImageJ, Biophotonics Int, vol.11, pp.36-42, 2004. ,
Interfering with hepatitis C virus IRES activity using RNA molecules identified by a novel in vitro selection method, Biological Chemistry, vol.386, issue.2, pp.183-190, 2005. ,
DOI : 10.1515/BC.2005.023
Functional analysis of the interaction between HCV 5'UTR and putative subunits of eukaryotic translation initiation factor eIF3, Nucleic Acids Research, vol.26, issue.13, pp.3179-3187, 1998. ,
DOI : 10.1093/nar/26.13.3179
Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry site, RNA, vol.12, issue.5, pp.894-902, 2006. ,
DOI : 10.1261/rna.2342306
Influence of correct secondary and tertiary RNA folding on the binding of cellular factors to the HCV IRES, Nucleic Acids Research, vol.28, issue.4, pp.875-885, 2000. ,
DOI : 10.1093/nar/28.4.875
A conserved RNA structure within the HCV IRES eIF3-binding site, Nature Structural Biology, vol.9, pp.375-380, 2002. ,
DOI : 10.1038/nsb785