Quadruplex DNA: sequence, topology and structure, Nucleic Acids Research, vol.34, issue.19, pp.5402-5415, 2006. ,
DOI : 10.1093/nar/gkl655
URL : http://doi.org/10.1093/nar/gkl655
Highly prevalent putative quadruplex sequence motifs in human DNA, Nucleic Acids Research, vol.33, issue.9, pp.2901-2907, 2005. ,
DOI : 10.1093/nar/gki553
Prevalence of quadruplexes in the human genome, Nucleic Acids Research, vol.33, issue.9, pp.2908-2916, 2005. ,
DOI : 10.1093/nar/gki609
Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription, Genome Research, vol.18, issue.2, pp.233-241, 2008. ,
DOI : 10.1101/gr.6905408
-Regulatory Elements in Human and Related Species, Journal of Medicinal Chemistry, vol.51, issue.18, pp.5641-5649, 2008. ,
DOI : 10.1021/jm800448a
URL : https://hal.archives-ouvertes.fr/jpa-00208183
Genome-wide prediction of G4 DNA as regulatory motifs: Role in Escherichia coli global regulation, Genome Research, vol.16, issue.5, pp.644-655, 2006. ,
DOI : 10.1101/gr.4508806
An RNA G-quadruplex in the 5??? UTR of the NRAS proto-oncogene modulates translation, Nature Chemical Biology, vol.13, issue.4, pp.218-221, 2007. ,
DOI : 10.1038/nchembio864
Predictable suppression of gene expression by 5'-UTR-based RNA quadruplexes, Nucleic Acids Research, vol.37, issue.20, pp.6811-6817, 2009. ,
DOI : 10.1093/nar/gkp696
DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase, Cell, vol.145, issue.5, pp.678-691, 2011. ,
DOI : 10.1016/j.cell.2011.04.015
Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals, Molecular BioSystems, vol.78, issue.12, pp.1703-1712, 2009. ,
DOI : 10.1039/b905132e
Stable G-quadruplexes are found outside nucleosome-bound regions, Molecular BioSystems, vol.365, issue.12, pp.1713-1719, 2009. ,
DOI : 10.1039/b905848f
Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide, Molecular BioSystems, vol.34, issue.12, pp.2439-2447, 2010. ,
DOI : 10.1111/j.1742-4658.2010.07814.x
Genome-Wide Analyses of Recombination Prone Regions Predict Role of DNA Structural Motif in Recombination, PLoS ONE, vol.32, issue.2013, p.4399, 2009. ,
DOI : 10.1371/journal.pone.0004399.s004
GRSDB: a database of quadruplex forming G-rich sequences in alternatively processed mammalian pre-mRNA sequences, Nucleic Acids Research, vol.34, issue.90001, pp.119-124, 2006. ,
DOI : 10.1093/nar/gkj073
G-quadruplexes in promoters throughout the human genome, Nucleic Acids Research, vol.35, issue.2, pp.406-413, 2007. ,
DOI : 10.1093/nar/gkl1057
Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions, Biochimie, vol.90, issue.8, pp.1149-1171, 2008. ,
DOI : 10.1016/j.biochi.2008.02.020
Structure, location and interactions of G-quadruplexes, FEBS Journal, vol.37, issue.17, pp.3452-3458, 2010. ,
DOI : 10.1111/j.1742-4658.2010.07758.x
Making sense of G-quadruplex and i-motif functions in oncogene promoters, FEBS Journal, vol.285, issue.17, pp.3459-3469, 2010. ,
DOI : 10.1111/j.1742-4658.2010.07759.x
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?, Nature Reviews Drug Discovery, vol.3599, issue.4, pp.261-275, 2011. ,
DOI : 10.1038/nrd3428
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription, Proceedings of the National Academy of Sciences, vol.99, issue.18, pp.11593-11598, 2002. ,
DOI : 10.1073/pnas.182256799
Demonstration that Drug-targeted Down-regulation of MYC in Non-Hodgkins Lymphoma Is Directly Mediated through the Promoter G-quadruplex, Journal of Biological Chemistry, vol.286, issue.47, pp.41018-41027, 2011. ,
DOI : 10.1074/jbc.M111.274720
A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity, Nucleic Acids Research, vol.36, issue.6, pp.1755-1769, 2008. ,
DOI : 10.1093/nar/gkm1069
The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents, Molecular Cancer Therapeutics, vol.7, issue.4, pp.880-889, 2008. ,
DOI : 10.1158/1535-7163.MCT-07-2119
Expression in Human Gastric Carcinoma Cells, Journal of the American Chemical Society, vol.133, issue.8, pp.2658-2663, 2011. ,
DOI : 10.1021/ja109474c
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription, Nucleic Acids Research, vol.34, issue.9, pp.2536-2549, 2006. ,
DOI : 10.1093/nar/gkl286
G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy, PLoS ONE, vol.86, issue.9, p.24421, 2011. ,
DOI : 10.1371/journal.pone.0024421.s008
Molecular Cloning of the Human Platelet-Derived Growth Factor Receptor ?? (PDGFR-??) Promoter and Drug Targeting of the G-Quadruplex-Forming Region To Repress PDGFR-?? Expression, Biochemistry, vol.49, issue.19, pp.4208-4219, 2010. ,
DOI : 10.1021/bi100330w
Promoter Quadruplex with Quindoline Derivatives, Journal of Medicinal Chemistry, vol.53, issue.11, pp.4390-4398, 2010. ,
DOI : 10.1021/jm100445e
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics, Nucleic Acids Research, vol.35, issue.22, pp.7429-7455, 2007. ,
DOI : 10.1093/nar/gkm711
Function and targeting of Gquadruplexes, Curr Opin Mol Ther, vol.11, pp.146-155, 2009. ,
Antitumor activity of G-quadruplex???interactive agent TMPyP4 in K562 leukemic cells, Cancer Letters, vol.261, issue.2, pp.226-234, 2008. ,
DOI : 10.1016/j.canlet.2007.11.017
Affinity and selectivity of G4 ligands measured by FRET, Nucleic Acids Symposium Series, vol.49, issue.1, pp.235-236, 2005. ,
DOI : 10.1093/nass/49.1.235
Binding of G-Quadruplex-interactive Agents to Distinct G-Quadruplexes Induces Different Biological Effects in MiaPaCa Cells, Nucleosides, Nucleotides and Nucleic Acids, vol.1, issue.10-12, pp.1801-1815, 2005. ,
DOI : 10.1016/j.cub.2004.12.031
Effects of cationic porphyrins as Gquadruplex interactive agents in human tumor cells, Cancer Res, vol.59, pp.639-644, 1999. ,
5,10,15,20-Tetrakis(N-Methyl-4-Pyridyl)-21H,23H-Porphine (TMPyP) as a Sensitizer for Singlet Oxygen Imaging in Cells: Characterizing the Irradiation-dependent Behavior of TMPyP in a Single Cell???, Photochemistry and Photobiology, vol.65, issue.1, pp.20-177, 2006. ,
DOI : 10.1021/ja00349a007
DNA damage and apoptosis induced by photosensitization of 5 (N-methyl-4-pyridyl)-21H,23H-porphyrin via singlet oxygen generation, Photochem Photobiol, vol.1015, issue.85, pp.20-1391, 2009. ,
Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression, Nucleic Acids Research, vol.37, issue.20, pp.6716-6722, 2009. ,
DOI : 10.1093/nar/gkp740
Small-molecule-mediated G-quadruplex isolation from human cells, Nature Chemistry, vol.12, issue.12, pp.1095-1098, 2010. ,
DOI : 10.1038/nchem.842
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands, Proceedings of the National Academy of Sciences, vol.99, issue.5, pp.2672-2677, 2002. ,
DOI : 10.1073/pnas.052698099
Ligands playing musical chairs with G-quadruplex DNA: A rapid and simple displacement assay for identifying selective G-quadruplex binders, Biochimie, vol.90, issue.8, pp.1207-1223, 2008. ,
DOI : 10.1016/j.biochi.2008.02.019
URL : https://hal.archives-ouvertes.fr/hal-00311781
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action, Proceedings of the National Academy of Sciences, vol.104, issue.44, pp.17347-17352, 2007. ,
DOI : 10.1073/pnas.0707365104
URL : https://hal.archives-ouvertes.fr/hal-00259071
Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands, Oncogene, vol.12, issue.18, pp.2917-2928, 2005. ,
DOI : 10.1038/sj.onc.1208468
Role of ATM in the telomere response to the G-quadruplex ligand 360A, Nucleic Acids Research, vol.36, issue.5, pp.1741-1754, 2008. ,
DOI : 10.1093/nar/gkn026
URL : https://hal.archives-ouvertes.fr/cea-00268952
Preferential binding of a G-quadruplex ligand to human chromosome ends, Nucleic Acids Research, vol.33, issue.13, pp.4182-4190, 2005. ,
DOI : 10.1093/nar/gki722
Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae, Nucleic Acids Research, vol.38, issue.13, pp.4337-4348, 2010. ,
DOI : 10.1093/nar/gkq136
Efficient Suppression of Gene Expression by Targeting 5???-UTR-Based RNA Quadruplexes with Bisquinolinium Compounds, ChemBioChem, vol.8, issue.11, pp.1663-1668, 2011. ,
DOI : 10.1002/cbic.201100228
Analyzing microarray data using CLANS, Bioinformatics, vol.23, issue.9, pp.1170-1171, 2007. ,
DOI : 10.1093/bioinformatics/btm079
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.103.7186
How long is too long? Effects of loop size on G-quadruplex stability, Nucleic Acids Research, vol.38, issue.21, pp.7858-7868, 2010. ,
DOI : 10.1093/nar/gkq639
Using principal component analysis to find correlations between loop-related and thermodynamic variables for G-quadruplex-forming sequences, Biochimie, vol.92, issue.8, pp.1016-1023, 2010. ,
DOI : 10.1016/j.biochi.2010.04.024
Loop-Length-Dependent Folding of G-Quadruplexes, Journal of the American Chemical Society, vol.126, issue.50, pp.16405-16415, 2004. ,
DOI : 10.1021/ja045154j
Loop Lengths of G-Quadruplex Structures Affect the G-Quadruplex DNA Binding Selectivity of the RGG Motif in Ewing???s Sarcoma, Biochemistry, vol.50, issue.23, pp.5369-5378, 2011. ,
DOI : 10.1021/bi2003857
Performance Assessment of Kernel Density Clustering for Gene Expression Profile Data, Comparative and Functional Genomics, vol.17, issue.3, pp.287-299, 2003. ,
DOI : 10.1002/cfg.290
GOToolBox: functional analysis of gene datasets based on Gene Ontology, Genome Biology, vol.5, issue.12, p.101, 2004. ,
DOI : 10.1186/gb-2004-5-12-r101
URL : https://hal.archives-ouvertes.fr/inserm-00095249
Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells, Nucleic Acids Research, vol.37, issue.13, pp.4194-4204, 2009. ,
DOI : 10.1093/nar/gkn1076
G-quadruplex nucleic acids as therapeutic targets, Current Opinion in Chemical Biology, vol.13, issue.3, pp.345-353, 2009. ,
DOI : 10.1016/j.cbpa.2009.04.637
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726962
Expression in Human Gastric Carcinoma Cells, Journal of the American Chemical Society, vol.133, issue.8, pp.2658-2663, 2011. ,
DOI : 10.1021/ja109474c
Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures, Biochimie, vol.93, issue.8, pp.1288-1296, 2011. ,
DOI : 10.1016/j.biochi.2011.05.011
Selection for the G4 DNA motif at the 5??? end of human genes, Molecular Carcinogenesis, vol.21, issue.4, pp.319-325, 2009. ,
DOI : 10.1002/mc.20496
The KRAS Promoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) ,
Quadruplex structures of muscle gene promoter sequences enhance in vivo MyoD-dependent gene expression, Nucleic Acids Research, vol.38, issue.7, pp.2369-2377, 2010. ,
DOI : 10.1093/nar/gkp1208
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential, Nucleic Acids Research, vol.38, issue.4, pp.1114-1122, 2010. ,
DOI : 10.1093/nar/gkp1103
Duplex Destabilization in Superhelical DNA is Predicted to Occur at Specific Transcriptional Regulatory Regions, Journal of Molecular Biology, vol.255, issue.3, pp.425-434, 1996. ,
DOI : 10.1006/jmbi.1996.0035
G4 motifs correlate with promoter-proximal transcriptional pausing in human genes, Nucleic Acids Research, vol.39, issue.12, pp.4975-4983, 2011. ,
DOI : 10.1093/nar/gkr079
BLAT---The BLAST-Like Alignment Tool, Genome Research, vol.12, issue.4, pp.656-664, 2002. ,
DOI : 10.1101/gr.229202
GeneMerge--post-genomic analysis, data mining, and hypothesis testing, Bioinformatics, vol.19, issue.7, pp.891-892, 2003. ,
DOI : 10.1093/bioinformatics/btg114
URL : http://bioinformatics.oxfordjournals.org/cgi/content/short/19/7/891