K. Scott, Taste Recognition: Food for Thought, Neuron, vol.48, issue.3, pp.455-464, 2005.
DOI : 10.1016/j.neuron.2005.10.015
URL : http://doi.org/10.1016/j.neuron.2005.10.015

H. Amrein and N. Thorne, Gustatory Perception and Behavior in Drosophila melanogaster, Current Biology, vol.15, issue.17, pp.673-684, 2005.
DOI : 10.1016/j.cub.2005.08.021
URL : http://doi.org/10.1016/j.cub.2005.08.021

M. Behrens and W. Meyerhof, Signaling in the Chemosensory Systems, Cellular and Molecular Life Sciences, vol.63, issue.13, pp.1501-1509, 2006.
DOI : 10.1007/s00018-006-6113-8

H. Ishimoto and T. Tanimura, Molecular neurophysiology of taste in Drosophila, Cellular and Molecular Life Sciences (CMLS), vol.61, issue.1, pp.10-18, 2004.
DOI : 10.1007/s00018-003-3182-9

H. Robertson, C. Warr, and J. Carlson, Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster, Proceedings of the National Academy of Sciences, vol.100, issue.Supplement 2, pp.14537-14542, 2003.
DOI : 10.1073/pnas.2335847100

A. Dahanukar, K. Foster, W. Van-der-goes-van-naters, and J. Carlson, A Gr receptor is required for response to the sugar trehalose in taste neurons of Drosophila, Nature Neuroscience, vol.4, issue.12, pp.1182-1186, 2001.
DOI : 10.1038/nn765

Y. Lee, S. Moon, and C. Montell, Multiple gustatory receptors required for the caffeine response in Drosophila, Proceedings of the National Academy of Sciences, vol.106, issue.11, pp.4495-4500, 2009.
DOI : 10.1073/pnas.0811744106

S. Moon, M. Kottgen, Y. Jiao, H. Xu, and C. Montell, A Taste Receptor Required for the Caffeine Response In Vivo, Current Biology, vol.16, issue.18, pp.1812-1817, 2006.
DOI : 10.1016/j.cub.2006.07.024

U. Wittstock and J. Gershenzon, Constitutive plant toxins and their role in defense against herbivores and pathogens, Current Opinion in Plant Biology, vol.5, issue.4, pp.300-307, 2002.
DOI : 10.1016/S1369-5266(02)00264-9

E. Bell, Nonprotein Amino Acids of Plants:?? Significance in Medicine, Nutrition, and Agriculture, Journal of Agricultural and Food Chemistry, vol.51, issue.10, pp.2854-2865, 2003.
DOI : 10.1021/jf020880w

L. Fowden, P. Lea, and E. Bell, The Nonprotein Amino Acids of Plants, Adv Enzymol Relat Areas Mol Biol, vol.54, pp.117-175, 1979.
DOI : 10.1002/9780470122952.ch3

E. Bell, Canavanine and related compounds in Leguminosae, Biochemical Journal, vol.70, issue.4, pp.617-619, 1958.
DOI : 10.1042/bj0700617
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1196716

E. Bell, Canavanine in the Leguminosae, Biochemical Journal, vol.75, issue.3, pp.618-620, 1960.
DOI : 10.1042/bj0750618
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1204519

G. Rosenthal, l -Canavanine: a higher plant insecticidal allelochemical, Amino Acids, vol.21, issue.3, pp.319-330, 2001.
DOI : 10.1007/s007260170017

E. Bell, M. Qureshi, B. Charlwood, D. Pilbeam, and C. Evans, The Variability of Free Amino Acids and Related Compounds in Legume Seeds, Basic Life Sci, vol.8, pp.397-412, 1976.
DOI : 10.1007/978-1-4684-2886-5_35

D. Dahlman and G. Rosenthal, Non-protein amino acid-insect interactions???I. Growth effects and symptomology of l-canavanine consumption by tobacco hornworm, Manduca sexta (L.), Comparative Biochemistry and Physiology Part A: Physiology, vol.51, issue.1, pp.33-36, 1975.
DOI : 10.1016/0300-9629(75)90409-0

G. Rosenthal, The Biological Effects and Mode of Action of L-Canavanine, a Structural Analogue of L-Arginine, The Quarterly Review of Biology, vol.52, issue.2, pp.155-178, 1977.
DOI : 10.1086/409853

G. Rosenthal and D. Dahlman, L-Canavanine and protein synthesis in the tobacco hornworm Manduca sexta., Proceedings of the National Academy of Sciences, vol.83, issue.1, pp.14-18, 1986.
DOI : 10.1073/pnas.83.1.14

C. Melangeli, G. Rosenthal, and D. Dalman, The biochemical basis for Lcanavanine tolerance by the tobacco budworm Heliothis virescens (Noctuidae), 1997.

G. Rosenthal, D. Janzen, and D. Dahlman, Degradation and detoxification of canavanine by a specialized seed predator, Science, vol.196, issue.4290, pp.658-660, 1977.
DOI : 10.1126/science.854740

J. Bockaert and J. Pin, Molecular tinkering of G protein-coupled receptors: an evolutionary success, The EMBO Journal, vol.18, issue.7, pp.1723-1729, 1999.
DOI : 10.1093/emboj/18.7.1723

H. Brauner-osborne, P. Wellendorph, and A. Jensen, Structure, Pharmacology and Therapeutic Prospects of Family C G-Protein Coupled Receptors, Current Drug Targets, vol.8, issue.1, pp.169-184, 2007.
DOI : 10.2174/138945007779315614

J. Pin, T. Galvez, and L. Prezeau, Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors, Pharmacology & Therapeutics, vol.98, issue.3, pp.325-354, 2003.
DOI : 10.1016/S0163-7258(03)00038-X

P. Conn and J. Pin, PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS, Annual Review of Pharmacology and Toxicology, vol.37, issue.1, pp.205-237, 1997.
DOI : 10.1146/annurev.pharmtox.37.1.205

M. Parmentier, J. Pin, J. Bockaert, and Y. Grau, Cloning and functional expression of a Drosophila metabotropic glutamate receptor expressed in the embryonic CNS, J Neurosci, vol.16, pp.6687-6694, 1996.

C. Mitri, M. Parmentier, J. Pin, J. Bockaert, and Y. Grau, Divergent Evolution in Metabotropic Glutamate Receptors: A NEW RECEPTOR ACTIVATED BY AN ENDOGENOUS LIGAND DIFFERENT FROM GLUTAMATE IN INSECTS, Journal of Biological Chemistry, vol.279, issue.10, pp.9313-9320, 2004.
DOI : 10.1074/jbc.M310878200

M. Crawley, Seed predators and plant population dynamics, Seeds, the ecology of regeneration in plant communities. Wallingford (UK): CAB International.. pp, pp.157-191, 1992.

N. Thorne, C. Chromey, S. Bray, and H. Amrein, Taste Perception and Coding in Drosophila, Current Biology, vol.14, issue.12, pp.1065-1079, 2004.
DOI : 10.1016/j.cub.2004.05.019

T. Awasaki and K. Kimura, pox-neuro is required for development of chemosensory bristles inDrosophila, Journal of Neurobiology, vol.36, issue.7, pp.707-721, 1997.
DOI : 10.1002/(SICI)1097-4695(19970620)32:7<707::AID-NEU6>3.0.CO;2-8

P. Clyne, C. Warr, and J. Carlson, Candidate Taste Receptors in Drosophila, Science, vol.287, issue.5459, pp.1830-1834, 2000.
DOI : 10.1126/science.287.5459.1830

S. Thibault, M. Singer, W. Miyazaki, B. Milash, and N. Dompe, A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac, Nature Genetics, vol.36, issue.3, pp.283-287, 2004.
DOI : 10.1038/ng1314

A. Parks, K. Cook, M. Belvin, N. Dompe, and R. Fawcett, Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome, Nature Genetics, vol.36, issue.3, pp.288-292, 2004.
DOI : 10.1038/ng1312

R. Stocker, The organization of the chemosensory system in Drosophila melanogaster: a rewiew, Cell and Tissue Research, vol.245, issue.2, pp.3-26, 1994.
DOI : 10.1007/BF00305372

R. Falk, N. Bleiser-avivi, and J. Atidia, Labellar taste organs ofDrosophila melanogaster, Journal of Morphology, vol.30, issue.2, pp.327-341, 1976.
DOI : 10.1002/jmor.1051500206

S. Nayak and R. Singh, Sensilla on the tarsal segments and mouthparts of adult Drosophila melanogaster meigen (Diptera : Drosophilidae), International Journal of Insect Morphology and Embryology, vol.12, issue.5-6, pp.273-291, 1983.
DOI : 10.1016/0020-7322(83)90023-5

K. Ray, V. Hartenstein, and V. Rodrigues, Development of the Taste Bristles on the Labellum of Drosophila melanogaster, Developmental Biology, vol.155, issue.1, pp.26-37, 1993.
DOI : 10.1006/dbio.1993.1003

M. Ebbs and H. Amrein, Taste and pheromone perception in the fruit fly Drosophila melanogaster, Pfl??gers Archiv - European Journal of Physiology, vol.389, issue.Suppl 2, pp.735-747, 2007.
DOI : 10.1007/s00424-007-0246-y

J. Kim and J. Carlson, Gene discovery by e-genetics: Drosophila odor and taste receptors, J Cell Sci, vol.115, pp.1107-1112, 2002.

K. Scott, R. Brady, . Jr, A. Cravchik, P. Morozov et al., A Chemosensory Gene Family Encoding Candidate Gustatory and Olfactory Receptors in Drosophila, Cell, vol.104, issue.5, pp.661-673, 2001.
DOI : 10.1016/S0092-8674(01)00263-X

L. Dunipace, S. Meister, C. Mcnealy, and H. Amrein, Spatially restricted expression of candidate taste receptors in the Drosophila gustatory system, Current Biology, vol.11, issue.11, pp.822-835, 2001.
DOI : 10.1016/S0960-9822(01)00258-5

Z. Wang, A. Singhvi, P. Kong, and K. Scott, Taste Representations in the Drosophila Brain, Cell, vol.117, issue.7, pp.981-991, 2004.
DOI : 10.1016/j.cell.2004.06.011

T. Inoshita and T. Tanimura, Cellular identification of water gustatory receptor neurons and their central projection pattern in Drosophila, Proceedings of the National Academy of Sciences, vol.103, issue.4, pp.1094-1099, 2006.
DOI : 10.1073/pnas.0502376103

N. Gendre, K. Luer, S. Friche, N. Grillenzoni, and A. Ramaekers, Integration of complex larval chemosensory organs into the adult nervous system of Drosophila, Development, vol.131, issue.1, pp.83-92, 2004.
DOI : 10.1242/dev.00879

V. Dethier, The hungry fly, 1976.
DOI : 10.1037/e400012009-006

A. Brand and N. Perrimon, Targeted gene expression as a means of altering cell fates and generating dominant phenotypes, Development, vol.118, pp.401-415, 1993.

S. Mcnabb, J. Baker, J. Agapite, H. Steller, and L. Riddiford, Disruption of a Behavioral Sequence by Targeted Death of Peptidergic Neurons in Drosophila, Neuron, vol.19, issue.4, pp.813-823, 1997.
DOI : 10.1016/S0896-6273(00)80963-0

S. Sweeney, K. Broadie, J. Keane, H. Niemann, O. Kane et al., Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects, Neuron, vol.14, issue.2, pp.341-351, 1995.
DOI : 10.1016/0896-6273(95)90290-2

L. Tompkins, M. Cardosa, F. White, and T. Sanders, Isolation and analysis of chemosensory behavior mutants in Drosophila melanogaster., Proceedings of the National Academy of Sciences, vol.76, issue.2, pp.884-887, 1979.
DOI : 10.1073/pnas.76.2.884

W. Kroeze, D. Sheffler, and B. Roth, G-protein-coupled receptors at a glance, Journal of Cell Science, vol.116, issue.24, pp.4867-4869, 2003.
DOI : 10.1242/jcs.00902

M. Marinissen and J. Gutkind, G-protein-coupled receptors and signaling networks: emerging paradigms, Trends in Pharmacological Sciences, vol.22, issue.7, pp.368-376, 2001.
DOI : 10.1016/S0165-6147(00)01678-3

S. Neves, P. Ram, and R. Iyengar, G Protein Pathways, Science, vol.296, issue.5573, pp.1636-1639, 2002.
DOI : 10.1126/science.1071550

H. Ishimoto, K. Takahashi, R. Ueda, and T. Tanimura, G-protein gamma subunit 1 is required for sugar reception in Drosophila, The EMBO Journal, vol.92, issue.18, pp.3259-3265, 2005.
DOI : 10.1016/S0092-8674(03)00071-0

K. Ueno, S. Kohatsu, C. Clay, M. Forte, and K. Isono, Gs?? Is Involved in Sugar Perception in Drosophila melanogaster, Journal of Neuroscience, vol.26, issue.23, pp.6143-6152, 2006.
DOI : 10.1523/JNEUROSCI.0857-06.2006

T. Ha and D. Smith, Insect Odorant Receptors: Channeling Scent, Cell, vol.133, issue.5, pp.761-763, 2008.
DOI : 10.1016/j.cell.2008.05.007

K. Sato, M. Pellegrino, T. Nakagawa, L. Vosshall, and K. Touhara, Insect olfactory receptors are heteromeric ligand-gated ion channels, Nature, vol.305, issue.7190, pp.1002-1006, 2008.
DOI : 10.1038/nature06850

B. Conklin, Z. Farfel, K. Lustig, J. D. Bourne, and H. , Substitution of three amino acids switches receptor specificity of Gq?? to that of Gi??, Nature, vol.363, issue.6426, pp.274-276, 1993.
DOI : 10.1038/363274a0

S. Hayashi, K. Ito, Y. Sado, M. Taniguchi, and A. Akimoto, GETDB, a database compiling expression patterns and molecular locations of a collection of gal4 enhancer traps, genesis, vol.83, issue.1-2, pp.58-61, 2002.
DOI : 10.1002/gene.10137

A. Dahanukar, Y. Lei, J. Kwon, and J. Carlson, Two Gr Genes Underlie Sugar Reception in Drosophila, Neuron, vol.56, issue.3, pp.503-516, 2007.
DOI : 10.1016/j.neuron.2007.10.024

S. Chyb, A. Dahanukar, A. Wickens, and J. Carlson, Drosophila Gr5a encodes a taste receptor tuned to trehalose, Proceedings of the National Academy of Sciences, vol.100, issue.Supplement 2, pp.14526-14530, 2003.
DOI : 10.1073/pnas.2135339100