SmpB as the handyman of tmRNA during trans-translation. - Archive ouverte HAL Access content directly
Journal Articles RNA Biol Year : 2011

SmpB as the handyman of tmRNA during trans-translation.

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Abstract

In the recent years, a wealth of genetic, biochemical and structural data focusing on various steps of bacterial trans-translation was reported. The early events, from stalled ribosome recognition, pre-accommodation to translocation have been recently investigated in great details. In comparison, the later events including 'elongation-termination' onto tmRNA reading frame and ribosome recycling are much less known. What follows is a summary of those data together with our personal view of the dynamics of trans-translation, with emphasis to the pivotal and leading roles that the SmpB protein has, being the essential conductor during the whole process.
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Dates and versions

inserm-00700119 , version 1 (23-05-2012)

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Brice Felden, Reynald Gillet. SmpB as the handyman of tmRNA during trans-translation.. RNA Biol, 2011, 8 (3), pp.440-9. ⟨10.4161/rna.8.3.15387⟩. ⟨inserm-00700119⟩
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