Skip to Main content Skip to Navigation
Journal articles

SmpB as the handyman of tmRNA during trans-translation.

Brice Felden 1 Reynald Gillet 2, *
* Corresponding author
2 Equipe Structure et Dynamique des Macromolécules
ICM - Interactions cellulaires et moléculaires
Abstract : In the recent years, a wealth of genetic, biochemical and structural data focusing on various steps of bacterial trans-translation was reported. The early events, from stalled ribosome recognition, pre-accommodation to translocation have been recently investigated in great details. In comparison, the later events including 'elongation-termination' onto tmRNA reading frame and ribosome recycling are much less known. What follows is a summary of those data together with our personal view of the dynamics of trans-translation, with emphasis to the pivotal and leading roles that the SmpB protein has, being the essential conductor during the whole process.
Document type :
Journal articles
Complete list of metadatas

Cited literature [77 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00700119
Contributor : Hervé de Villemeur <>
Submitted on : Wednesday, May 23, 2012 - 9:17:13 AM
Last modification on : Wednesday, October 7, 2020 - 10:10:05 AM
Long-term archiving on: : Friday, August 24, 2012 - 2:20:34 AM

File

FeldenRNA8-3.pdf
Publisher files allowed on an open archive

Identifiers

Citation

Brice Felden, Reynald Gillet. SmpB as the handyman of tmRNA during trans-translation.. RNA Biol, 2011, 8 (3), pp.440-9. ⟨10.4161/rna.8.3.15387⟩. ⟨inserm-00700119⟩

Share

Metrics

Record views

367

Files downloads

444