B. Clé-menç-on, M. Rey, A. C. Dianoux, V. Tré-zé-guet, G. J. Lauquin et al., ADP/ATP Carrier Isoform 2, Journal of Biological Chemistry, vol.283, issue.17, pp.11218-11225, 2008.
DOI : 10.1074/jbc.M709565200

B. Clé-menç-on, M. Rey, V. Tré-zé-guet, E. Forest, L. Pelosi et al., Conformational dynamics and role of the RRRMMM signature sequence methionines, J. Biol. Chem, vol.2, issue.286, pp.36119-361131, 2011.

M. Rey, P. Man, B. Clé-menç-on, V. Tré-zé-guet, G. Brandolin et al., Conformational Dynamics of the Bovine Mitochondrial ADP/ATP Carrier Isoform 1 Revealed by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry, Journal of Biological Chemistry, vol.285, issue.45, pp.34981-34990, 2010.
DOI : 10.1074/jbc.M110.146209

URL : https://hal.archives-ouvertes.fr/hal-00520989

A. S. Verkman, Solute and macromolecule diffusion in cellular aqueous compartments, Trends in Biochemical Sciences, vol.27, issue.1, pp.27-33, 2002.
DOI : 10.1016/S0968-0004(01)02003-5

M. Azimi, Y. Jamali, and M. R. Mofrad, Accounting for Diffusion in Agent Based Models of Reaction-Diffusion Systems with Application to Cytoskeletal Diffusion, PLoS ONE, vol.59, issue.9, pp.25306-25307, 2011.
DOI : 10.1371/journal.pone.0025306.g010

O. Medalia, I. Weber, A. S. Frangakis, D. Nicastro, G. Gerisch et al., Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography, Science, vol.298, issue.5596, pp.599-620, 2002.
DOI : 10.1126/science.1076184

S. B. Zimmermann and S. Trach, Estimation of macromolecule concentrations and excluded volume effects for the cytoplasm of Escherichia coli, Journal of Molecular Biology, vol.222, issue.3, pp.1209-1213, 1991.
DOI : 10.1016/0022-2836(91)90499-V

B. A. Scalettar, J. R. Abney, and C. R. Hackenbrock, Dynamics, structure, and function are coupled in the mitochondrial matrix., Proc. Natl. Acad. Sci, pp.8057-8061, 1991.
DOI : 10.1073/pnas.88.18.8057

J. A. Dix and A. S. Verkman, Crowding Effects on Diffusion in Solutions and Cells, Annual Review of Biophysics, vol.37, issue.1, pp.247-263, 2008.
DOI : 10.1146/annurev.biophys.37.032807.125824

V. A. Saks, Z. A. Khuchua, E. V. Vasilyeva, O. Yu-belikova, and A. Kuznetsov, Metabolic compartimentation and substrate channeling in muscle cells. Role of coupled creatine kinases in vivo regulation of cellular respiration?A synthesis, Mol. Cell. Biochem, vol.133, pp.155-192, 1994.

G. Wieczorek and P. Zielenkiewicz, Influence of Macromolecular Crowding on Protein-Protein Association Rates???a Brownian Dynamics Study, Biophysical Journal, vol.95, issue.11, pp.5030-5036, 2008.
DOI : 10.1529/biophysj.108.136291

S. B. Zimmerman and B. Harrison, Macromolecular crowding increases binding of DNA polymerase to DNA: an adaptive effect., Proceedings of the National Academy of Sciences, vol.84, issue.7, pp.1871-1875, 1987.
DOI : 10.1073/pnas.84.7.1871

A. P. Minton, The Influence of Macromolecular Crowding and Macromolecular Confinement on Biochemical Reactions in Physiological Media, Journal of Biological Chemistry, vol.276, issue.14, pp.10577-10580, 2001.
DOI : 10.1074/jbc.R100005200

B. Van-den-berg, R. J. Ellis, and C. M. Dobson, Effects of macromolecular crowding on protein folding and aggregation, The EMBO Journal, vol.18, issue.24, pp.6927-6933, 1999.
DOI : 10.1093/emboj/18.24.6927

B. Van-den-berg, R. Wain, C. M. Dobson, and R. J. Ellis, Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell, The EMBO Journal, vol.22, issue.15, pp.3870-3875, 2000.
DOI : 10.1093/emboj/19.15.3870

A. Galan, B. Sot, O. Llorca, J. L. Carrascosa, J. M. Valpuesta et al., Excluded Volume Effects on the Refolding and Assembly of an Oligomeric Protein: GroEL, A CASE STUDY, Journal of Biological Chemistry, vol.276, issue.2, pp.957-964, 2001.
DOI : 10.1074/jbc.M006861200

H. Dong, S. Qin, and H. Zhou, Effects of Macromolecular Crowding on Protein Conformational Changes, PLoS Computational Biology, vol.39, issue.7, pp.1-1000833, 2010.
DOI : 10.1371/journal.pcbi.1000833.s005

G. R. Welch, On the role of organized multienzyme systems in cellular metabolism: A general synthesis, Progress in Biophysics and Molecular Biology, vol.32, pp.103-191, 1977.
DOI : 10.1016/0079-6107(78)90019-6

P. Tompa, J. Batke, and J. Ovà-di, How to determine the efficiency of intermediate transfer in an interacting enzyme system? FEBS Lett, pp.244-248, 1987.

J. Ovà-di and V. Saks, On the origin of intracellular compartmentation and organized metabolic systems, Mol. Cell. Biochem, pp.256-257, 2004.

J. Philbert, One and half century of diffusion: Fick, Einstein, before and beyond. Diffus. Fundam, pp.4-6, 2006.

D. K. Srivastava and S. A. Bernhard, Metabolite transfer via enzyme-enzyme complexes, Science, vol.234, issue.4780, pp.1081-1086, 1986.
DOI : 10.1126/science.3775377

X. Huang, H. M. Holden, and F. M. Raushel, Channeling of Substrates and Intermediates in Enzyme-Catalyzed Reactions, Annual Review of Biochemistry, vol.70, issue.1, pp.149-180, 2001.
DOI : 10.1146/annurev.biochem.70.1.149

C. J. Van-noorden and G. N. Jonges, Analysis of enzyme reactions in situ, The Histochemical Journal, vol.27, issue.2, pp.101-118, 1995.
DOI : 10.1007/BF00243905

E. Boonacker, J. Stap, A. Koehler, and C. J. Van-noorden, The need for metabolic mapping in living cells and tissues, Acta Histochemica, vol.106, issue.2, pp.89-96, 2004.
DOI : 10.1016/j.acthis.2004.01.002

P. Srere, The metabolon, Trends in Biochemical Sciences, vol.10, issue.3, pp.109-110, 1985.
DOI : 10.1016/0968-0004(85)90266-X

P. A. Srere, Complexes of Sequential Metabolic Enzymes, Annual Review of Biochemistry, vol.56, issue.1, pp.89-124, 1987.
DOI : 10.1146/annurev.bi.56.070187.000513

F. M. Clarke and C. J. Masters, On the association of glycolytic enzymes with structural proteins of skeletal muscle, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.381, issue.1, pp.37-46, 1975.
DOI : 10.1016/0304-4165(75)90187-7

J. H. Ottaway and J. Mowbray, The Role of Compartmentation in the Control of Glycolysis, Curr. Top. Cell. Regul, vol.12, pp.107-208, 1977.
DOI : 10.1016/B978-0-12-152812-6.50010-X

B. I. Kurganov and N. P. Sugrobova, Supramolecular organization of glycolytic enzymes, Journal of Theoretical Biology, vol.116, issue.4, pp.509-526, 1985.
DOI : 10.1016/S0022-5193(85)80086-2

S. P. Brooks and K. B. Storey, The effect of enzyme-enzyme complexes on the overall glycolytic rate in vivo, Biochem. Int, vol.25, pp.477-489, 1991.

D. W. Maughan, J. A. Henkin, and J. Vigoreaux, Concentrations of Glycolytic Enzymes and Other Cytosolic Proteins in the Diffusible Fraction of a Vertebrate Muscle Proteome, Molecular & Cellular Proteomics, vol.4, issue.10, pp.1541-1549, 2005.
DOI : 10.1074/mcp.M500053-MCP200

C. Masters, Interactions between glycolytic enzymes and components of the cytomatrix, The Journal of Cell Biology, vol.99, issue.1, pp.222-225, 1984.
DOI : 10.1083/jcb.99.1.222s

C. J. Masters, S. Reid, and M. Don, Glycolysis ? new concepts in an old pathway, Molecular and Cellular Biochemistry, vol.76, issue.1, pp.3-14, 1987.
DOI : 10.1007/BF00219393

K. W. Volker, C. A. Reinitz, and H. R. Knull, Glycolytic enzymes and assembly of microtubule networks, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, vol.112, issue.3, pp.503-514, 1995.
DOI : 10.1016/0305-0491(95)00096-8

V. F. Waingeh, C. D. Gustafson, E. I. Kozliak, S. L. Lowe, H. R. Knull et al., Glycolytic Enzyme Interactions with Yeast and Skeletal Muscle F-Actin, Biophysical Journal, vol.90, issue.4, pp.1371-1384, 2006.
DOI : 10.1529/biophysj.105.070052

C. Vé-lot, M. B. Mixon, M. Teige, and P. A. Srere, Model of a quinary structure between Krebs TCA cycle enzymes: A model for the metabolon, Biochemistry, vol.25, pp.14271-14276, 1997.

S. Rajakumari and G. Daum, Multiple Functions as Lipase, Steryl Ester Hydrolase, Phospholipase, and Acyltransferase of Tgl4p from the Yeast Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.285, issue.21, pp.15769-15776, 2010.
DOI : 10.1074/jbc.M109.076331

N. Guelzim, F. Mariotti, P. G. Martin, F. Lasserre, T. Pineau et al., A role for PPAR?? in the regulation of arginine metabolism and nitric oxide synthesis, Amino Acids, vol.23, issue.4, pp.969-979, 2011.
DOI : 10.1007/s00726-010-0797-7

H. Bhaskaran and J. J. Perona, Two-Step Aminoacylation of tRNA without Channeling in Archaea, Journal of Molecular Biology, vol.411, issue.4, pp.854-869, 2011.
DOI : 10.1016/j.jmb.2011.06.039

Y. H. Ko, M. Delannoy, J. Hullihen, W. Chiu, and P. L. Pedersen, Mitochondrial ATP Synthasome: CRISTAE-ENRICHED MEMBRANES AND A MULTIWELL DETERGENT SCREENING ASSAY YIELD DISPERSED SINGLE COMPLEXES CONTAINING THE ATP SYNTHASE AND CARRIERS FOR Pi AND ADP/ATP, Journal of Biological Chemistry, vol.278, issue.14, pp.12305-12309, 2003.
DOI : 10.1074/jbc.C200703200

P. Mitchell, Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism, Nature, vol.182, issue.4784, pp.144-148, 1961.
DOI : 10.1002/jez.1400510306

P. Mitchell, Compartmentation and Communication in Living Systems. Ligand Conduction: a General Catalytic Principle in Chemical, Osmotic and Chemiosmotic Reaction Systems, European Journal of Biochemistry, vol.235, issue.1, pp.1-20, 1979.
DOI : 10.1016/0003-9861(69)90411-1

V. Saks, Integrated and Organized Cellular Energetic Systems, In Molecular System Bioenergetics. Energy for Life, vol.34, issue.257, pp.94-96, 2007.
DOI : 10.1002/9780470048672.wecb699

V. Saks, R. Guzun, N. Timohhina, K. Tepp, M. Varikmaa et al., Structure???function relationships in feedback regulation of energy fluxes in vivo in health and disease: Mitochondrial Interactosome, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1797, issue.6-7, pp.678-697, 2010.
DOI : 10.1016/j.bbabio.2010.01.011

E. Pfaff, M. Klingenberg, and H. W. Heldt, Unspecific permeation and specific exchange of adenine nucleotides in liver mitochondria, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.104, issue.1, pp.312-315, 1965.
DOI : 10.1016/0304-4165(65)90258-8

E. D. Duee and P. V. Vignais, ??xchange entre adenine-nucleotides extra- et intramitochondriaux, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.107, issue.1, pp.184-188, 1965.
DOI : 10.1016/0304-4165(65)90419-8

M. Klingenberg and E. Pfaff, Metabolic control in mitochondria by adenine nucleotide translocation, Biochem. Soc. Symp, vol.27, pp.105-122, 1968.

P. Vignais, The mitochondrial adenine nucleotide translocator, Journal of Bioenergetics, vol.69, issue.1, pp.9-17, 1976.
DOI : 10.1007/BF01559386

M. Klingenberg, The ADP-ATP Translocation in mitochondria, a membrane potential controlled transport, The Journal of Membrane Biology, vol.82, issue.2, pp.97-105, 1980.
DOI : 10.1007/BF01875961

K. Lanoue, S. M. Mizani, and M. Klingenberg, Electrical imbalance of adenine nucleotide transport across the mitochondrial membrane, J. Biol. Chem, vol.253, pp.191-198, 1978.

J. Duszynski, K. Bogucka, G. Letko, U. Kuster, W. Kunz et al., Relationship between the energy cost of ATP transport and ATP synthesis in mitochondria, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.637, issue.2, pp.217-223, 1981.
DOI : 10.1016/0005-2728(81)90160-2

R. Kramer and M. Klingenberg, Modulation of the reconstituted adenine nucleotide exchange by membrane potential, Biochemistry, vol.19, issue.3, pp.556-560, 1980.
DOI : 10.1021/bi00544a025

E. Pebay-peyroula, C. Dahout-gonzalez, R. Kahn, V. Trezeguet, G. J. Lauquin et al., Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside, Nature, vol.426, issue.6962, pp.39-44, 2003.
DOI : 10.1038/nature02056

A. J. Robinson and R. S. Kunji, Mitochondrial carries in the cytoplasmic state have a common substrate binding site, Proc. Natl. Acad. Sci, pp.2617-2622, 2006.

M. J. Berardi, W. M. Shih, S. C. Harrison, and J. J. Chou, Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching, Nature, vol.125, issue.7358, pp.109-113, 2011.
DOI : 10.1038/nature10257

P. Riccio, H. Aquila, and M. Klingenberg, Purification of the carboxy-atractylate binding protein from mitochondria, FEBS Letters, vol.55, issue.1, pp.133-138, 1975.
DOI : 10.1016/0014-5793(75)80127-X

H. Aquila, W. Eiermann, W. Babel, and M. Klingenberg, Isolation of the ADP/ATP Translocator from Beef Heart Mitochondria as the Bongkrekate-Protein Complex, European Journal of Biochemistry, vol.15, issue.2, pp.549-560, 1978.
DOI : 10.1016/0014-5793(77)80848-X

H. Hackenberg and M. Klingenberg, Molecular weight and hydrodynamic parameters of the adenosine 5'-diphosphate-adenosine 5'-triphosphate carrier in Triton X-100, Biochemistry, vol.19, issue.3, pp.548-555, 1980.
DOI : 10.1021/bi00544a024

M. R. Block, G. Zaccai, G. J. Lauquin, and P. Vignais, Small angle neutron scattering of the mitochondrial ADP/ATP carrier protein in detergent, Biochem. Biophys. Res. Commun, vol.109, pp.1882-471

A. Schroers, A. Burkovski, H. Wohlrab, and R. Kramer, The Phosphate Carrier from Yeast Mitochondria: DIMERIZATION IS A PREREQUISITE FOR FUNCTION, Journal of Biological Chemistry, vol.273, issue.23, pp.14269-14276, 1998.
DOI : 10.1074/jbc.273.23.14269

R. Kotaria, J. A. Mayor, D. E. Walters, and R. S. Kaplan, Oligomeric state of wild-type and cysteine-less yeast mitochondrial citrate transport proteins, Journal of Bioenergetics and Biomembranes, vol.31, issue.6, pp.543-549, 1999.
DOI : 10.1023/A:1005460810527

G. Brandolin, Y. Dupont, and P. Vignais, Exploration of the nucleotide binding sites of the isolated ADP/ATP carrier protein from beef heart mitochondria. 2. Probing of the nucleotide sites by formycin triphosphate, a fluorescent transportable analog of ATP, Biochemistry, vol.21, issue.25, pp.6348-6353, 1982.
DOI : 10.1021/bi00268a005

M. R. Block and P. Vignais, Substrate-site interactions in the membrane-bound adenine-nucleotide carrier as disclosed by ADP and ATP analogs, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.767, issue.2, pp.369-376, 1984.
DOI : 10.1016/0005-2728(84)90207-X

H. Nury, C. Dahout-gonzalez, V. Trezeguet, G. Lauquin, G. Brandolin et al., Structural basis for lipid-mediated interactions between mitochondrial ADP/ATP carrier monomers, FEBS Letters, vol.269, issue.27, pp.6031-6036, 2005.
DOI : 10.1016/j.febslet.2005.09.061

URL : https://hal.archives-ouvertes.fr/hal-00068260

L. Bamber, M. Harding, P. J. Butler, and E. Kunji, Yeast mitochondrial ADP/ATP carriers are monomeric in detergents, Proc. Natl. Acad. Sci, pp.16224-16229, 2006.
DOI : 10.1073/pnas.0607640103

L. Bamber, M. Harding, M. Monne, D. J. Slotboom, and E. R. Kunji, The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes, Proc. Natl. Acad. Sci, pp.10830-10834, 2007.
DOI : 10.1073/pnas.0703969104

L. Bamber, D. J. Slotboom, and E. R. Kunji, Yeast Mitochondrial ADP/ATP Carriers Are Monomeric in Detergents as Demonstrated by Differential Affinity Purification, Journal of Molecular Biology, vol.371, issue.2, pp.388-395, 2007.
DOI : 10.1016/j.jmb.2007.05.072

G. Lauquin, J. Lunardi, and P. Vignais, Effect of genetic and physiological manipulations on the kinetic and binding parameters of the adenine nucleotide translocator in Saccharomyces cerevisiae and Candida utilis, Biochimie, vol.58, issue.10, pp.1213-1220, 1976.
DOI : 10.1016/S0300-9084(76)80120-4

G. Gavurnikova, L. Sabova, I. Kissova, P. Haviernik, and J. Kolarov, Transcription of the AAC1 Gene Encoding an Isoform of Mitochondrial ADP/ATP Carrier in Saccharomyces cerevisiae is Regulated by Oxygen in a Heme-Independent Manner, European Journal of Biochemistry, vol.49, issue.3, pp.759-763, 1996.
DOI : 10.1016/0076-6879(83)01013-7

J. E. Lawson and M. G. Douglas, Separate genes encode functionally equivalent ADP/ATP carrier proteins in Saccharomyces cerevisiae. Isolation and analysis of AAC2, J. Biol. Chem, vol.263, pp.14812-14818, 1988.

J. Kolarov, N. Kolarova, and N. Nelson, A third ADP/ATP translocator gene in yeast, J. Biol. Chem, vol.265, pp.12711-12716, 1990.

L. Sabova, I. Zeman, F. Supek, and J. Kolarov, Transcriptional control of AAC3 gene encoding mitochondrial ADP/ATP translocator in Saccharomyces cerevisiae by oxygen, heme and ROX1 factor, European Journal of Biochemistry, vol.86, issue.1, pp.547-553, 1993.
DOI : 10.1016/0092-8674(83)90309-4

G. Stepien, A. Torroni, A. B. Chung, J. A. Hodge, and D. C. Wallace, Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation, J. Biol. Chem, vol.267, pp.14592-14597, 1992.

A. Chevrollier, D. Loiseau, B. Chabi, G. Renier, and O. Douay, Malthiè ry, Y.; Stepien, G. ANT2 isoform required for cancer cell glycolysis, J. Bioenerg. Biomembr, vol.35, pp.307-316, 2005.

V. Dolce, P. Scarcia, D. Iacopetta, and F. Palmieri, A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution, FEBS Letters, vol.41, issue.3, pp.633-637, 2005.
DOI : 10.1016/j.febslet.2004.12.034

V. Tré-zé-guet, L. Pé-losi, G. J. Lauquin, and G. Brandolin, The mitochondrial ADP/ATP carrier: functional and structural studies in the route of elucidating pathophysiological aspects, Journal of Bioenergetics and Biomembranes, vol.279, issue.37, pp.435-443, 2008.
DOI : 10.1007/s10863-008-9178-2

H. Wohlrab, PURIFICATION AND RECONSTITUTION OF THE MITOCHONDRIAL PHOSPHATE TRANSPORTER, Annals of the New York Academy of Sciences, vol.2, issue.1 Second Intern, pp.364-367, 1980.
DOI : 10.1016/0003-2697(76)90506-6

H. Wohlrab, Molecular aspects of inorganic phosphate transport in mitochondria, Biochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, vol.853, issue.2, pp.115-134, 1986.
DOI : 10.1016/0304-4173(86)90007-8

R. Kramer and F. Palmieri, Molecular aspects of isolated and reconstituted carrier proteins from animal mitochondria, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.974, issue.1, pp.1-23, 1989.
DOI : 10.1016/S0005-2728(89)80160-4

J. P. Wehrle and P. L. Pedersen, Phosphate transport processes in eukaryotic cells, The Journal of Membrane Biology, vol.262, issue.3, pp.199-213, 1989.
DOI : 10.1007/BF01871006

H. Aquila, T. A. Link, and M. Klingenberg, Solute carriers involved in energy transfer of mitochondria form a homologous protein family, FEBS Letters, vol.164, issue.1, pp.1-9, 1987.
DOI : 10.1016/0014-5793(87)81546-6

J. E. Walker and M. J. Runswick, The mitochondrial transport protein superfamily, Journal of Bioenergetics and Biomembranes, vol.3, issue.5, pp.435-446, 1993.
DOI : 10.1007/BF01108401

A. Phelps, C. T. Schobert, and H. Wohlrab, Cloning and characterization of the mitochondrial phosphate transport protein gene from the yeast Saccharomyces cerevisiae, Biochemistry, vol.30, issue.1, pp.248-252, 1991.
DOI : 10.1021/bi00215a035

V. Zara, K. Dietmeier, A. Palmisano, A. Vozza, J. Rassow et al., Yeast mitochondria lacking the phosphate carrier/p32 are blocked in phosphate transport but can import preproteins after regeneration of a membrane potential., Molecular and Cellular Biology, vol.16, issue.11, pp.6524-6531, 1996.
DOI : 10.1128/MCB.16.11.6524

H. Aquila, T. A. Link, and M. Klingenberg, The uncoupling protein from brown fat mitochondria is related to the mitochondrial ADP/ATP carrier. Analysis of sequence homologies and of folding of the protein in the membrane, EMBO J, vol.4, pp.2369-2376, 1985.

J. Kuan, M. H. Saier, and . Jr, The Mitochondrial Carrier Family of Transport Proteins: Structural, Functional, and Evolutionary Relationships, Critical Reviews in Biochemistry and Molecular Biology, vol.3, issue.3, pp.209-233, 1993.
DOI : 10.1146/annurev.bi.48.070179.004255

R. Stappen and R. Kramer, Functional properties of the reconstituted phosphate carrier from bovine heart mitochondria: Evidence for asymmetric orientation and characterization of three different transport modes, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1149, issue.1, pp.40-48, 1993.
DOI : 10.1016/0005-2736(93)90022-R

R. Stappen and R. Kramer, Kinetic mechanism of phosphate/phosphate and phosphate/OH? antiports catalyzed by reconstituted phosphate carrier from beef heart mitochondria, J. Biol. Chem, vol.269, pp.11240-11246, 1994.

K. Herick, R. Stappen, and R. Krä-mer, Comparaison of Functional and Structural Aspects of the Reconstituted Phosphate and Aspartate/Glutamate Carrier from Mitochondria, In Thirty Years of Progress in Mitochondrial Bioenergetics and Molecular Biology, pp.83-87, 1995.

A. Schroers, R. Kramer, and H. Wohlrab, The reversible antiport-uniport conversion of the phosphate carrier from yeast mitochondria depends on the presence of a single cysteine, J. Biol. Chem, vol.272, pp.10558-10564, 1997.

M. Zackova, R. Kramer, and P. Jezek, Interaction of mitochondrial phosphate carrier with fatty acids and hydrophobic phosphate analogs, The International Journal of Biochemistry & Cell Biology, vol.32, issue.5, pp.499-508, 2000.
DOI : 10.1016/S1357-2725(00)00006-6

H. Wohlrab and C. Briggs, Yeast Mitochondrial Phosphate Transport Protein Expressed in Escherichia coli. Site-Directed Mutations at Threonine-43 and at a Similar Location in the Second Tandem Repeat (Isoleucine-141), Biochemistry, vol.33, issue.32, pp.9371-9375, 1994.
DOI : 10.1021/bi00198a001

A. Schroers, A. Burkovski, H. Wohlrab, and R. Kramer, The Phosphate Carrier from Yeast Mitochondria: DIMERIZATION IS A PREREQUISITE FOR FUNCTION, Journal of Biological Chemistry, vol.273, issue.23, pp.14269-14276, 1998.
DOI : 10.1074/jbc.273.23.14269

M. Klingenberg, The ADP and ATP transport in mitochondria and its carrier, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1778, issue.10, pp.1978-2021, 2008.
DOI : 10.1016/j.bbamem.2008.04.011

J. A. Mayr, O. Merkel, S. D. Kohlwein, B. R. Gebhardt, H. Böhles et al., Mitochondrial Phosphate???Carrier Deficiency: A Novel Disorder of Oxidative Phosphorylation, The American Journal of Human Genetics, vol.80, issue.3, pp.478-489, 2007.
DOI : 10.1086/511788

M. Colombini, Voltage gating in the mitochondrial channel, VDAC, The Journal of Membrane Biology, vol.323, issue.2, pp.103-111, 1989.
DOI : 10.1007/BF01871775

M. Forte, H. R. Guy, and C. A. Mannella, Molecular genetics of the VDAC ion channel: Structural model and sequence analysis, Journal of Bioenergetics and Biomembranes, vol.5, issue.4, pp.341-350, 1987.
DOI : 10.1007/BF00768537

C. A. Mannella, W. D. Bonner, and . Jr, Biochemical characteristics of the outer membranes of plant mitochondria, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.413, issue.2, pp.213-225, 1975.
DOI : 10.1016/0005-2736(75)90105-4

S. J. Schein, M. Colombini, and A. Finkelstein, Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria, The Journal of Membrane Biology, vol.228, issue.1, pp.99-120, 1976.
DOI : 10.1007/BF01869662

M. Colombini, A candidate for the permeability pathway of the outer mitochondrial membrane, Nature, vol.246, issue.5714, pp.643-645, 1979.
DOI : 10.1016/0005-2736(78)90269-9

V. De-pinto, O. Ludwig, J. Krause, R. Benz, and F. Palmieri, Porin pores of mitochondrial outer membranes from high and low eukaryotic cells: biochemical and biophysical characterization, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.894, issue.2, pp.109-119, 1987.
DOI : 10.1016/0005-2728(87)90180-0

M. Colombini, VDAC: The channel at the interface between mitochondria and the cytosol, Molecular and Cellular Biochemistry, vol.256, issue.1/2, pp.256-257, 2004.
DOI : 10.1023/B:MCBI.0000009862.17396.8d

C. A. Mannella, Conformational Changes in the Mitochondrial Channel Protein, VDAC, and Their Functional Implications, Journal of Structural Biology, vol.121, issue.2, pp.207-218, 1998.
DOI : 10.1006/jsbi.1997.3954

V. Shoshan-barmatz and D. Gincel, The Voltage-Dependent Anion Channel: Characterization, Modulation, and Role in Mitochondrial Function in Cell Life and Death, Cell Biochemistry and Biophysics, vol.39, issue.3, pp.279-292, 2003.
DOI : 10.1385/CBB:39:3:279

M. Y. Liu and M. Colombini, Regulation of mitochondrial respiration by controlling the permeability of the outer membrane through the mitochondrial channel, VDAC, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1098, issue.2, pp.255-260, 1098.
DOI : 10.1016/S0005-2728(05)80344-5

S. V. Lemeshko and V. V. Lemeshko, Metabolically Derived Potential on the Outer Membrane of Mitochondria: A Computational Model, Biophysical Journal, vol.79, issue.6, pp.2785-2800, 2000.
DOI : 10.1016/S0006-3495(00)76518-0

S. V. Lemeshko and V. Lemeshko, Energy flux modulation on the outer membrane of mitochondria by metabolically-derived potential, Molecular and Cellular Biochemistry, vol.256, issue.1/2, pp.256-257, 2004.
DOI : 10.1023/B:MCBI.0000009864.77216.00

E. Blachly-dyson, J. Song, W. J. Wolfgang, M. Colombini, and M. Forte, Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein., Molecular and Cellular Biology, vol.17, issue.10, pp.5727-5738, 1997.
DOI : 10.1128/MCB.17.10.5727

A. C. Lee, X. Xu, E. Blachly-dyson, M. Forte, and M. Colombini, The Role of Yeast VDAC Genes on the Permeability of the Mitochondrial Outer Membrane, Journal of Membrane Biology, vol.161, issue.2, pp.173-181, 1998.
DOI : 10.1007/s002329900324

M. Dihanich, K. Suda, and G. Schatz, A yeast mutant lacking mitochondrial porin is respiratory-deficient, but can recover respiration with simultaneous accumulation of an 86-KD extramitochondrial protein, EMBO J, vol.6, pp.723-728, 1987.

J. Michejda, X. J. Guo, and G. J. Lauquin, The respiration of cells and mitochondria of porin deficient yeast mutants is coupled, Biochemical and Biophysical Research Communications, vol.171, issue.1, pp.354-361, 1990.
DOI : 10.1016/0006-291X(90)91401-D

M. Bayrhuber, T. Meins, M. Habeck, S. Becker, K. Giller et al., Structure of the human voltage-dependent anion channel, Proc. Natl. Acad. Sci, pp.15370-15375, 2008.
DOI : 10.1073/pnas.0808115105

S. Hiller, R. G. Garces, T. J. Malia, V. Y. Orekhov, M. Colombini et al., Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles, Science, vol.321, issue.5893, pp.1206-1210, 2008.
DOI : 10.1126/science.1161302

R. Ujwal, D. Cascio, V. Chaptal, P. Ping, and J. Abramson, Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation, Channels, vol.3, issue.3, pp.167-170, 2009.
DOI : 10.4161/chan.3.3.9196

S. Abu-hamad, N. Arbel, D. Calo, L. Arzoine, A. Israelson et al., The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins, Journal of Cell Science, vol.122, issue.11, pp.1906-1916, 2009.
DOI : 10.1242/jcs.040188

M. Colombini, VDAC structure, selectivity, and dynamics, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1818, issue.6, 2012.
DOI : 10.1016/j.bbamem.2011.12.026

URL : http://doi.org/10.1016/j.bbamem.2011.12.026

H. Florke, F. P. Thinnes, H. Winkelbach, U. Stadtmuller, G. Paetzold et al., Channel Active Mammalian Porin, Purified from Crude Membrane Fractions of Human B Lymphocytes and Bovine Skeletal Muscle, Reversibly Binds Adenosine Triphosphate (ATP), Biological Chemistry Hoppe-Seyler, vol.375, issue.8, pp.513-520, 1994.
DOI : 10.1515/bchm3.1994.375.8.513

A. C. Lee, M. Zizi, and M. Colombini, ?-NADH decreases the permeability of the mitochondrial outer membrane to ADP by a factor of 6, J. Biol. Chem, vol.269, pp.30974-30980, 1994.

G. Yehezkel, N. Hadad, H. Zaid, S. Sivan, and V. Shoshan-barmatz, Nucleotide-binding Sites in the Voltage-dependent Anion Channel: CHARACTERIZATION AND LOCALIZATION, Journal of Biological Chemistry, vol.281, issue.9, pp.5938-5946, 2006.
DOI : 10.1074/jbc.M510104200

T. Rostovtseva and M. Colombini, VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function, Biophysical Journal, vol.72, issue.5, pp.1954-1962, 1997.
DOI : 10.1016/S0006-3495(97)78841-6

T. K. Rostovtseva and S. M. Bezrukov, ATP Transport Through a Single Mitochondrial Channel, VDAC, Studied by Current Fluctuation Analysis, Biophysical Journal, vol.74, issue.5, pp.2365-2373, 1998.
DOI : 10.1016/S0006-3495(98)77945-7

T. K. Rostovtseva, A. Komarov, S. M. Bezrukov, and M. Colombini, VDAC Channels Differentiate between Natural Metabolites and Synthetic Molecules, Journal of Membrane Biology, vol.187, issue.2, pp.147-156, 2002.
DOI : 10.1007/s00232-001-0159-1

T. K. Rostovtseva, A. Komarov, S. M. Bezrukov, and M. Colombini, Dynamics of Nucleotides in VDAC Channels: Structure-Specific Noise Generation, Biophysical Journal, vol.82, issue.1, pp.193-205, 2002.
DOI : 10.1016/S0006-3495(02)75386-1

G. Yehezkel, N. Hadad, H. Zaid, S. Sivan, and V. Shoshan-barmatz, Nucleotide-binding Sites in the Voltage-dependent Anion Channel: CHARACTERIZATION AND LOCALIZATION, Journal of Biological Chemistry, vol.281, issue.9, pp.5938-5946, 2006.
DOI : 10.1074/jbc.M510104200

G. Yehezkel, S. Abu-hamad, and V. Shoshan-barmatz, An N-terminal nucleotide-binding site in VDAC1: Involvement in regulating mitochondrial function, Journal of Cellular Physiology, vol.1241, issue.2, pp.551-561, 2007.
DOI : 10.1002/jcp.21048

M. J. Berridge, M. D. Bootman, and P. Lipp, Calcium?A life and death signal, Nature, vol.395, issue.6703, pp.645-648, 1998.
DOI : 10.1038/27094

F. C. Mooren and R. K. Kinne, Cellular calcium in health and disease, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1406, issue.2, pp.127-151, 1998.
DOI : 10.1016/S0925-4439(98)00006-4

M. Crompton, S. Virji, V. Doyle, N. Johnson, and J. M. Ward, The mitochondrial permeability transition pore, Biochemical Society Symposium, vol.66, pp.167-179, 1999.
DOI : 10.1042/bss0660167

M. Crompton, The mitochondrial permeability transition pore and its role in cell death, Biochemical Journal, vol.341, issue.2, pp.233-249, 1999.
DOI : 10.1042/bj3410233

T. Pozzan and R. Rizzuto, The renaissance of mitochondrial calcium transport, European Journal of Biochemistry, vol.237, issue.3, pp.5269-5273, 2000.
DOI : 10.1046/j.1432-1327.2000.01567.x

V. Shoshan-barmatz and D. Gincel, The Voltage-Dependent Anion Channel: Characterization, Modulation, and Role in Mitochondrial Function in Cell Life and Death, Cell Biochemistry and Biophysics, vol.39, issue.3, pp.279-292, 2003.
DOI : 10.1385/CBB:39:3:279

A. Israelson, S. Abu-hamad, H. Zaid, and E. Nahon, Shoshan-Barmatz, V. Localization of the voltage-dependent anion channel-1 Ca 2+ -binding sites, Cell Calcium, pp.235-244, 2006.

R. A. Nakashima, P. S. Mangan, M. Colombini, and P. L. Pedersen, Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC, Biochemistry, vol.25, issue.5, pp.1015-1021, 1986.
DOI : 10.1021/bi00353a010

A. Jamal and J. A. , Involvement of Porin N,N-dicyclohexylcarbodiimide-Reactive Domain in Hexokinase Binding to the Outer Mitochondrial Membrane, The Protein Journal, vol.1126, issue.1, pp.1-8, 2005.
DOI : 10.1007/s10930-004-0600-2

H. Zaid, S. Abu-hamad, A. Israelson, and I. Nathan, The voltage-dependent anion channel-1 modulates apoptotic cell death, Cell Death and Differentiation, vol.46, issue.7, pp.751-760, 2005.
DOI : 10.1038/227680a0

S. Abu-hamad, H. Zaid, A. Israelson, E. Nahon, and V. Shoshan-barmatz, Hexokinase-I Protection against Apoptotic Cell Death Is Mediated via Interaction with the Voltage-dependent Anion Channel-1: MAPPING THE SITE OF BINDING, Journal of Biological Chemistry, vol.283, issue.19, pp.13482-13490, 2008.
DOI : 10.1074/jbc.M708216200

I. Marzo, C. Brenner, N. Zamzami, S. A. Susin, G. Beutner et al., The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2???related Proteins, The Journal of Experimental Medicine, vol.155, issue.8, pp.1261-1271, 1998.
DOI : 10.1016/0092-8674(95)90422-0

G. Beutner, A. Ruck, B. Riede, and D. Brdiczka, Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1368, issue.1, pp.7-18, 1998.
DOI : 10.1016/S0005-2736(97)00175-2

A. P. Halestrap and C. Brenner, The Adenine Nucleotide Translocase: A Central Component of the Mitochondrial Permeability Transition Pore and Key Player in Cell Death, Current Medicinal Chemistry, vol.10, issue.16, pp.1507-1525, 2003.
DOI : 10.2174/0929867033457278

D. Brdiczka, P. Kaldis, and T. Wallimann, In vitro complex formation between the octamer of mitochondrial creatine kinase and porin, J. Biol. Chem, vol.269, pp.27640-27644, 1994.

O. Stachowiak, U. Schlattner, M. Dolder, and T. Wallimann, Oligomeric state and membrane binding behaviour of creatine kinase isoenzymes: Implications for cellular function and mitochondrial structure, Mol. Cell. Biochem, vol.184, pp.141-151, 1998.
DOI : 10.1007/978-1-4615-5653-4_11

URL : https://hal.archives-ouvertes.fr/inserm-00390792

T. Wallimann, M. Wyss, D. Brdiczka, K. Nicolay, and H. M. Eppenberger, Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ???phosphocreatine circuit??? for cellular energy homeostasis, Biochemical Journal, vol.281, issue.1, pp.21-40, 1992.
DOI : 10.1042/bj2810021

U. Schlattner, M. Dolder, and T. Wallimann, Tokarska-Schlattner, M. Mitochondrial creatine kinase and mitochondrial outer membrane porin show a direct interaction that is modulated by calcium, J. Biol .Chem, vol.276, pp.48027-48030, 2001.

Y. Tsujimoto and S. Shimizu, VDAC regulation by the Bcl-2 family of proteins, Cell Death and Differentiation, vol.7, issue.12, pp.1174-1181, 2000.
DOI : 10.1038/sj.cdd.4400780

H. Azoulay-zohar, A. Israelson, S. Abu-hamad, and V. Shoshan-barmatz, In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death, Biochemical Journal, vol.377, issue.2, pp.347-355, 2004.
DOI : 10.1042/bj20031465

J. G. Pastorino and J. B. Hoek, Hexokinase II: The Integration of Energy Metabolism and Control of Apoptosis, Current Medicinal Chemistry, vol.10, issue.16, pp.1535-1551, 2003.
DOI : 10.2174/0929867033457269

M. Carre, N. Andre, G. Carles, H. Borghi, L. Brichese et al., Tubulin Is an Inherent Component of Mitochondrial Membranes That Interacts with the Voltage-dependent Anion Channel, Journal of Biological Chemistry, vol.277, issue.37, pp.33664-33669, 2002.
DOI : 10.1074/jbc.M203834200

C. Monge, N. Beraud, A. V. Kuznetsov, T. Rostovtseva, D. Sackett et al., Regulation of respiration in brain mitochondria and synaptosomes: restrictions of ADP diffusion in??situ, roles of tubulin, and mitochondrial creatine kinase, Molecular and Cellular Biochemistry, vol.76, issue.3, pp.147-165, 2008.
DOI : 10.1007/s11010-008-9865-7

URL : https://hal.archives-ouvertes.fr/inserm-00390936

T. K. Rostovtseva and S. M. Bezrukov, VDAC regulation: role of cytosolic proteins and mitochondrial lipids, Journal of Bioenergetics and Biomembranes, vol.1706, issue.3, pp.163-170, 2008.
DOI : 10.1007/s10863-008-9145-y

D. L. Sackett, Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration, Proc. Natl. Acad. Sci, pp.18746-18751, 2008.

G. Szabadkai, K. Bianchi, P. Vá-rnai, D. De-stefani, M. R. Wieckowski et al., channels, The Journal of Cell Biology, vol.297, issue.257, pp.901-911, 2006.
DOI : 10.1091/mbc.E05-08-0740

I. R. Boldogh, H. C. Yang, and L. A. Pon, Mitochondrial Inheritance in Budding Yeast, Traffic, vol.9, issue.6, pp.368-374, 2001.
DOI : 10.1083/jcb.145.6.1199

C. A. Mannella, Structure of the outer mitochondrial membrane: ordered arrays of porelike subunits in outer-membrane fractions from neurospora crassa mitochondria, The Journal of Cell Biology, vol.94, issue.3, pp.680-687, 1982.
DOI : 10.1083/jcb.94.3.680

M. Lindé-n and P. Gellerfors, Hydrodynamic properties of porin isolated from outer membranes of rat liver mitochondria, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.736, issue.1, pp.125-129, 1983.
DOI : 10.1016/0005-2736(83)90177-3

Y. Shi, C. Jiang, Q. Chen, and H. Tang, One-step on-column affinity refolding purification and functional analysis of recombinant human VDAC1, Biochemical and Biophysical Research Communications, vol.303, issue.2, pp.475-482, 2003.
DOI : 10.1016/S0006-291X(03)00359-0

V. Shoshan-barmatz, R. Zalk, D. Gincel, and N. Vardi, Subcellular localization of VDAC in mitochondria and ER in the cerebellum, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1657, issue.2-3, pp.105-114, 2004.
DOI : 10.1016/j.bbabio.2004.02.009

R. Zalk, A. Israelson, E. S. Garty, H. Azoulay-zohar, and V. Shoshan-barmatz, release from mitochondria, Biochemical Journal, vol.386, issue.1, pp.73-83, 2005.
DOI : 10.1042/BJ20041356

R. P. Goncalves, N. Buzhynskyy, V. Prima, J. N. Sturgis, and S. Scheuring, Supramolecular Assembly of VDAC in Native Mitochondrial Outer Membranes, Journal of Molecular Biology, vol.369, issue.2, pp.413-418, 2007.
DOI : 10.1016/j.jmb.2007.03.063

B. W. Hoogenboom, K. Suda, A. Engel, and D. Et-fotiadis, The Supramolecular Assemblies of Voltage-dependent Anion Channels in the Native Membrane, Journal of Molecular Biology, vol.370, issue.2, pp.246-255, 2007.
DOI : 10.1016/j.jmb.2007.04.073

S. W. Cowan, T. Schirmer, G. Rummel, M. Steiert, R. Ghosh et al., Crystal structures explain functional properties of two E. coli porins, Nature, vol.358, issue.6389, pp.727-733, 1992.
DOI : 10.1038/358727a0

V. De-pinto, R. Benz, and F. Palmieri, Interaction of non-classical detergents with the mitochondrial porin. A new purification procedure and characterization of the pore-forming unit, European Journal of Biochemistry, vol.728, issue.1, pp.179-187, 1989.
DOI : 10.1016/0014-5793(81)80152-4

H. Freitag, W. Neupert, and R. Benz, Purification and Characterisation of a Pore Protein of the Outer Mitochondrial Membrane from Neurospora crassa, European Journal of Biochemistry, vol.15, issue.3, pp.629-636, 1982.
DOI : 10.1111/j.1432-1033.1982.tb06578.x

B. Popp, A. Schmid, and R. Benz, Role of Sterols in the Functional Reconstitution of Water-Soluble Mitochondrial Porins from Different Organisms, Biochemistry, vol.34, issue.10, pp.3352-3361, 1995.
DOI : 10.1021/bi00010a026

R. Kramer, Cholesterol as activator of ADP-ATP exchange in reconstituted liposomes and in mitochondria, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.693, issue.2, pp.296-304, 1982.
DOI : 10.1016/0005-2736(82)90435-7

T. K. Rostovtseva, N. Kazemi, M. Weinrich, and S. M. Bezrukov, Voltage Gating of VDAC Is Regulated by Nonlamellar Lipids of Mitochondrial Membranes, Journal of Biological Chemistry, vol.281, issue.49, pp.37496-37506, 2006.
DOI : 10.1074/jbc.M602548200

W. E. Jacobus and A. L. Lehninger, Creatine kinase of rat heart mitochondria. Coupling of creatine phosphorylation to electron transport, J. Biol. Chem, vol.248, pp.4803-4810, 1973.

S. P. Bessman and C. L. Carpenter, The Creatine-Creatine Phosphate Energy Shuttle, Annual Review of Biochemistry, vol.54, issue.1, pp.831-862, 1985.
DOI : 10.1146/annurev.bi.54.070185.004151

T. Wallimann, M. Wyss, D. Brdiczka, K. Nicolay, and H. M. Et-eppenberger, Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ???phosphocreatine circuit??? for cellular energy homeostasis, Biochemical Journal, vol.281, issue.1, pp.21-40, 1992.
DOI : 10.1042/bj2810021

U. Schlattner, M. Forstner, M. Eder, O. Stachowiak, K. Fritz-wolf et al., Functional aspects of the X-ray structure of mitochondrial creatine kinase: A molecular physiology approach, Mol. Cell. Biochem, vol.184, pp.125-140, 1998.
DOI : 10.1007/978-1-4615-5653-4_10

URL : https://hal.archives-ouvertes.fr/inserm-00390791

U. Schlattner, S. Ramirez, A. Bruckner, L. Kay, C. Polge et al., Mitochondrial kinases and their molecular interaction with cardiolipin, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1788, issue.10, pp.2032-2047, 2009.
DOI : 10.1016/j.bbamem.2009.04.018

URL : https://hal.archives-ouvertes.fr/inserm-00422473

R. Hovius, H. Lambrechts, K. Nicolay, and B. De-kruijff, Improved methods to isolate and subfractionate rat liver mitochondria. Lipid composition of the inner and outer membrane, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1021, issue.2, pp.217-226, 1990.
DOI : 10.1016/0005-2736(90)90036-N

U. Schlattner, F. Gehring, N. Vernoux, M. Tokarska-schlattner, D. Neumann et al., C-terminal Lysines Determine Phospholipid Interaction of Sarcomeric Mitochondrial Creatine Kinase, Journal of Biological Chemistry, vol.279, issue.23, pp.24334-24342, 2004.
DOI : 10.1074/jbc.M314158200

URL : https://hal.archives-ouvertes.fr/inserm-00390858

C. Hoppel, J. Kerner, P. Turkaly, P. Minkler, and B. Tandler, Isolation of Hepatic Mitochondrial Contact Sites: Previously Unrecognized Inner Membrane Components, Analytical Biochemistry, vol.302, issue.1, pp.60-69, 2002.
DOI : 10.1006/abio.2001.5531

O. Speer, N. Bä-ck, T. Buerklen, D. Brdiczka, A. Koretsky et al., Octameric mitochondrial creatine kinase induces and stabilizes contact sites between the inner and outer membrane, Biochemical Journal, vol.385, issue.2, pp.445-450, 2005.
DOI : 10.1042/BJ20040386

D. G. Brdiczka, D. B. Zorov, and S. S. Sheu, Mitochondrial contact sites: Their role in energy metabolism and apoptosis, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.1762, issue.2, pp.1762-148, 2006.
DOI : 10.1016/j.bbadis.2005.09.007

S. M. Claypool, Y. Oktay, P. Boontheung, J. A. Loo, and C. M. Koehler, Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane, The Journal of Cell Biology, vol.50, issue.5, pp.937-950, 2008.
DOI : 10.1074/jbc.M504955200

G. Brandolin, A. Le-saux, V. Tré-zé-guet, P. V. Vignais, and G. J. Lauquin, Biochemical Characterisation of the Isolated Anc2 Adenine Nucleotide Carrier from Saccharomyces cerevisiae Mitochondria, Biochemical and Biophysical Research Communications, vol.192, issue.1, pp.143-150, 1993.
DOI : 10.1006/bbrc.1993.1393

C. Hunte and S. Richers, Lipids and membrane protein structures, Current Opinion in Structural Biology, vol.18, issue.4, pp.406-411, 2008.
DOI : 10.1016/j.sbi.2008.03.008

P. J. Booth and A. R. Curran, Membrane protein folding, Current Opinion in Structural Biology, vol.9, issue.1, pp.115-195, 1999.
DOI : 10.1016/S0959-440X(99)80015-3

W. Dowhan and M. Bogdanov, Lipid-Dependent Membrane Protein Topogenesis, Annual Review of Biochemistry, vol.78, issue.1, pp.515-540, 2009.
DOI : 10.1146/annurev.biochem.77.060806.091251

M. K. Dienhart and A. M. Rosemary, The Yeast Aac2 Protein Exists in Physical Association with the Cytochrome bc1-COX Supercomplex and the TIM23 Machinery, Molecular Biology of the Cell, vol.19, issue.9, pp.3934-3943, 2008.
DOI : 10.1091/mbc.E08-04-0402

M. Harner, C. Körner, D. Walther, D. Mokranjac, J. Kaesmacher et al., The mitochondrial contact site complex, a determinant of mitochondrial architecture, The EMBO Journal, vol.581, issue.21, pp.4356-4370, 2011.
DOI : 10.1038/emboj.2011.379

S. Hoppins, S. R. Collins, A. Cassidy-stone, E. Hummel, R. M. Devay et al., A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria, The Journal of Cell Biology, vol.6, issue.2, pp.323-340, 2011.
DOI : 10.1016/j.febslet.2007.06.052

K. Von-der-malsburg, J. M. Müller, M. Bohnert, S. Oeljeklaus, P. Kwiatkowska et al., Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis, Developmental Cell, vol.21, issue.4, pp.694-707, 2011.
DOI : 10.1016/j.devcel.2011.08.026

I. Wittig, Structural organization of mitochondrial ATP synthase, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1777, issue.7-8, pp.592-598, 2008.
DOI : 10.1016/j.bbabio.2008.04.027

J. Nunnari, W. F. Marshall, A. Straight, A. Murray, J. W. Sedat et al., Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA., Molecular Biology of the Cell, vol.8, issue.7, pp.1233-1242, 1997.
DOI : 10.1091/mbc.8.7.1233