GPSy: a cross-species gene prioritization system for conserved biological processes--application in male gamete development.

Ramona Britto 1 Olivier Sallou 2, 3 Olivier Collin 2, 3 Grégoire Michaux 4 Michael Primig 5 Frédéric Chalmel 5, *
* Corresponding author
1 Irset - Institut de recherche en santé, environnement et travail
2 Plateforme bioinformatique GenOuest [Rennes]
IRISA - Institut de Recherche en Informatique et Systèmes Aléatoires, UR1 - Université de Rennes 1, Plateforme Génomique Santé Biogenouest®, Inria Rennes – Bretagne Atlantique
3 SED [Rennes] - Service Expérimentation et Développement
4 IGDR - Institut de Génétique et Développement de Rennes
5 Transcriptional networks in gametogenesis and cancer
Irset - Institut de recherche en santé, environnement et travail
Abstract : We present gene prioritization system (GPSy), a cross-species gene prioritization system that facilitates the arduous but critical task of prioritizing genes for follow-up functional analyses. GPSy's modular design with regard to species, data sets and scoring strategies enables users to formulate queries in a highly flexible manner. Currently, the system encompasses 20 topics related to conserved biological processes including male gamete development discussed in this article. The web server-based tool is freely available at http://gpsy.genouest.org.
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Ramona Britto, Olivier Sallou, Olivier Collin, Grégoire Michaux, Michael Primig, et al.. GPSy: a cross-species gene prioritization system for conserved biological processes--application in male gamete development.. Nucleic Acids Research, Oxford University Press, 2012, 40 (W1), pp.W458-W465. ⟨10.1093/nar/gks380⟩. ⟨inserm-00696905⟩

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