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Cannabis use, ischemic stroke, and multifocal intracranial vasoconstriction: a prospective study in 48 consecutive young patients.: Ischemic Stroke and Cannabis

Abstract : BACKGROUND AND PURPOSE: Our objective was to evaluate the relationship between cannabis use and ischemic stroke in a young adult population. METHODS: Forty-eight consecutive young patients admitted for acute ischemic stroke participated in the study. First-line screening was performed, including blood tests, cardiovascular investigations, and urine analysis for cannabinoids. If no etiology was found, 3D rotational angiography and cerebrospinal fluid analysis were performed. A control was planned through neurovascular imaging within 3 to 6 months. RESULTS: In this series, there was multifocal intracranial stenosis associated with cannabis use in 21% (n=10). CONCLUSIONS: Multifocal angiopathy associated with cannabis consumption could be an important cause of ischemic stroke in young people.
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Valérie Wolff, Valérie Lauer, Olivier Rouyer, François Sellal, Nicolas Meyer, et al.. Cannabis use, ischemic stroke, and multifocal intracranial vasoconstriction: a prospective study in 48 consecutive young patients.: Ischemic Stroke and Cannabis. Stroke, American Heart Association, 2011, 42 (6), pp.1778-80. ⟨10.1161/STROKEAHA.110.610915⟩. ⟨inserm-00676840⟩

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