Cannabis use, ischemic stroke, and multifocal intracranial vasoconstriction: a prospective study in 48 consecutive young patients.: Ischemic Stroke and Cannabis

Valérie Wolff 1, * Valérie Lauer 1 Olivier Rouyer 2 François Sellal 3 Nicolas Meyer 4 Jean Sébastien Raul 5 Cécile Sabourdy 6 Fazel Boujan 7 Christine Jahn 7 Rémy Beaujeux 7 Christian Marescaux 1
* Auteur correspondant
1 Unité Neuro-vasculaire
2 MSP - Mitochondrie, stress oxydant et protection musculaire
3 Service de neurologie
4 Laboratoire de biostatistique
5 Laboratoire de Toxicologie
6 ANTE-INSERM U836, équipe 9, Dynamique des réseaux synchrones épileptiques
Unité Neuro-vasculaire
7 Service de radiologie [Strasbourg]
Abstract : BACKGROUND AND PURPOSE: Our objective was to evaluate the relationship between cannabis use and ischemic stroke in a young adult population. METHODS: Forty-eight consecutive young patients admitted for acute ischemic stroke participated in the study. First-line screening was performed, including blood tests, cardiovascular investigations, and urine analysis for cannabinoids. If no etiology was found, 3D rotational angiography and cerebrospinal fluid analysis were performed. A control was planned through neurovascular imaging within 3 to 6 months. RESULTS: In this series, there was multifocal intracranial stenosis associated with cannabis use in 21% (n=10). CONCLUSIONS: Multifocal angiopathy associated with cannabis consumption could be an important cause of ischemic stroke in young people.
Keywords : stroke in young adults vasospasm cannabis
Type de document :
Article dans une revue
Stroke, American Heart Association, 2011, 42 (6), pp.1778-80. 〈10.1161/STROKEAHA.110.610915〉
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Valérie Wolff, Valérie Lauer, Olivier Rouyer, François Sellal, Nicolas Meyer, et al.. Cannabis use, ischemic stroke, and multifocal intracranial vasoconstriction: a prospective study in 48 consecutive young patients.: Ischemic Stroke and Cannabis. Stroke, American Heart Association, 2011, 42 (6), pp.1778-80. 〈10.1161/STROKEAHA.110.610915〉. 〈inserm-00676840〉

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