Skip to Main content Skip to Navigation
Journal articles

Autophagy: A protective mechanism in response to stress and inflammation.

Abstract : Autophagy is one of the intracellular systems that is responsible for protein trafficking (degradation/recycling) in eukaryotic cells. This ubiquitous process contributes to cytosolic homeostasis, but its deregulation is often associated with various pathologies, including neurodegenerative diseases and cancer and pathologies with an altered inflammatory response. This review provides an overview of autophagy and discusses its regulation, function and future therapeutic possibilities, with a focus on the role of autophagy in inflammation.
Complete list of metadata

Cited literature [1 references]  Display  Hide  Download
Contributor : D* Heymann Connect in order to contact the contributor
Submitted on : Friday, February 10, 2012 - 6:29:46 PM
Last modification on : Wednesday, April 27, 2022 - 3:42:39 AM
Long-term archiving on: : Friday, May 11, 2012 - 3:05:19 AM


Files produced by the author(s)


  • HAL Id : inserm-00669003, version 1
  • PUBMED : 16729721



Dominique Heymann. Autophagy: A protective mechanism in response to stress and inflammation.. Current Opinion in Investigational Drugs, Thomson Reuters (Professional), 2006, 7 (5), pp.443-50. ⟨inserm-00669003⟩



Record views


Files downloads