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Autophagy: A protective mechanism in response to stress and inflammation.

Abstract : Autophagy is one of the intracellular systems that is responsible for protein trafficking (degradation/recycling) in eukaryotic cells. This ubiquitous process contributes to cytosolic homeostasis, but its deregulation is often associated with various pathologies, including neurodegenerative diseases and cancer and pathologies with an altered inflammatory response. This review provides an overview of autophagy and discusses its regulation, function and future therapeutic possibilities, with a focus on the role of autophagy in inflammation.
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https://www.hal.inserm.fr/inserm-00669003
Contributor : D* Heymann <>
Submitted on : Friday, February 10, 2012 - 6:29:46 PM
Last modification on : Thursday, April 5, 2018 - 10:36:26 AM
Long-term archiving on: : Friday, May 11, 2012 - 3:05:19 AM

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  • HAL Id : inserm-00669003, version 1
  • PUBMED : 16729721

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Dominique Heymann. Autophagy: A protective mechanism in response to stress and inflammation.. Current Opinion in Investigational Drugs, Thomson Reuters (Professional), 2006, 7 (5), pp.443-50. ⟨inserm-00669003⟩

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