Skip to Main content Skip to Navigation
Journal articles

Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies.

Abstract : BACKGROUND: Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. CASE PRESENTATION: We report the first case of CHIKV infection with chronic associated rheumatism in a patient who developed progressive erosive arthritis with expression of inflammatory mediators and persistence of specific IgM antibodies over 24 months following infection. CONCLUSIONS: Understanding the specific features of chikungunya virus as well as how the virus interacts with its host are essential for the prevention, treatment or cure of chikungunya disease.
Document type :
Journal articles
Complete list of metadatas

Cited literature [30 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00668479
Contributor : Ed. Bmc <>
Submitted on : Thursday, February 9, 2012 - 5:24:09 PM
Last modification on : Friday, December 13, 2019 - 11:28:04 AM
Long-term archiving on: : Thursday, November 22, 2012 - 11:56:24 AM

Files

Identifiers

Citation

Denis Malvy, Khaled Ezzedine, Maria Mamani-Matsuda, Brigitte Autran, Hugues Tolou, et al.. Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies.. BMC Infectious Diseases, BioMed Central, 2009, 9 (1), pp.200. ⟨10.1186/1471-2334-9-200⟩. ⟨inserm-00668479⟩

Share

Metrics

Record views

574

Files downloads

1061