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Journal articles
A case report of pseudoprogression followed by complete remission after proton-beam irradiation for a low-grade glioma in a teenager: the value of dynamic contrast-enhanced MRI
Abstract : A fourteen years-old boy was treated post-operatively with proton therapy for a recurrent low-grade oligodendroglioma located in the tectal region. Six months after the end of irradiation (RT), a new enhancing lesion appeared within the radiation fields. To differentiate disease progression from radiation-induced changes, dynamic susceptibility contrast-enhanced (DSCE) MRI was used with a T2* sequence to study perfusion and permeability characteristics simultaneously. Typically, the lesion showed hypoperfusion and hyperpermeability compared to the controlateral normal brain. Without additional treatment but a short course of steroids, the image disappeared over a six months period allowing us to conclude for a pseudo-progression. The patient is alive in complete remission more than 2 years post-RT.
Cited literature [22 references]
https://www.hal.inserm.fr/inserm-00668468
Contributor : Ed. Bmc <>
Submitted on : Thursday, February 9, 2012 - 5:20:57 PM
Last modification on : Wednesday, September 16, 2020 - 4:57:00 PM
Long-term archiving on: : Wednesday, December 14, 2016 - 5:22:40 AM
Contributor : Ed. Bmc <>
Submitted on : Thursday, February 9, 2012 - 5:20:57 PM
Last modification on : Wednesday, September 16, 2020 - 4:57:00 PM
Long-term archiving on: : Wednesday, December 14, 2016 - 5:22:40 AM