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Pediatric hemophagocytic syndromes: a diagnostic and therapeutic challenge.

Abstract : Pediatric hemophagocytic syndrome (HS) is a severe and often fatal clinical disorder. This syndrome is frequently unrecognized, and thus, affected children may receive suboptimal management, leading to an increase in mortality. The purpose of this review is to provide a clinical guide to (1) the recognition of HS based on clinical, biologic, and pathologic features; (2) the identification of the primary cause of HS in a given affected child; and (3) the initiation of effective treatment in a timely manner.
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Nada Jabado, Christine Mccusker, Geneviève de Saint-Basile. Pediatric hemophagocytic syndromes: a diagnostic and therapeutic challenge.. Allergy, Asthma and Clinical Immunology, BioMed Central, 2005, 1 (4), pp.142-60. ⟨10.1186/1710-1492-1-4-142⟩. ⟨inserm-00663938⟩



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