N. Auersperg, A. Wong, K. Choi, S. Kang, and P. Leung, Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology, Endocrine Reviews, vol.22, issue.2, pp.255-288, 2001.
DOI : 10.1210/er.22.2.255

R. Yancik and . Ovarian-cancer, Ovarian cancer: Age contrasts in incidence, histology, disease stage at diagnosis, and mortality, Cancer, vol.36, issue.Suppl, pp.517-523, 1993.
DOI : 10.1002/cncr.2820710205

A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu et al., Cancer Statistics, 2008, Cancer statistics, pp.71-96, 2008.
DOI : 10.3322/CA.2007.0010

M. Raspollini and G. Taddei, Tumor markers in ovarian carcinoma, International Journal of Gynecology & Obstetrics, vol.4, issue.(7), pp.175-181, 2007.
DOI : 10.1016/j.ijgo.2007.02.011

D. Adamio, F. Zollo, O. Moraca, R. Ayroldi, E. Bruscoli et al., A New Dexamethasone-Induced Gene of the Leucine Zipper Family Protects T Lymphocytes from TCR/CD3-Activated Cell Death, Immunity, vol.7, issue.6, pp.803-812, 1997.
DOI : 10.1016/S1074-7613(00)80398-2

C. Riccardi, M. Cifone, and G. Migliorati, Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes, Cell Death and Differentiation, vol.6, issue.12, pp.1182-1189, 1999.
DOI : 10.1038/sj.cdd.4400609

C. Riccardi, O. Zollo, G. Nocentini, S. Bruscoli, A. Bartoli et al., Glucocorticoid hormones in the regulation of cell death, Therapie, vol.55, pp.165-169, 2000.

E. Ayroldi, G. Migliorati, S. Bruscoli, C. Marchetti, O. Zollo et al., Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB, Blood, vol.98, issue.3, pp.743-753, 2001.
DOI : 10.1182/blood.V98.3.743

D. Berrebi, S. Bruscoli, N. Cohen, A. Foussat, G. Migliorati et al., Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10, Blood, vol.101, issue.2, pp.729-738, 2003.
DOI : 10.1182/blood-2002-02-0538

N. Cohen, E. Mouly, H. Hamdi, M. Maillot, M. Pallardy et al., GILZ expression in human dendritic cells redirects their maturation and prevents antigen-specific T lymphocyte response, Blood, vol.107, issue.5, pp.2037-2044, 2006.
DOI : 10.1182/blood-2005-07-2760

V. Godot, G. Garcia, F. Capel, M. Arock, I. Durand-gasselin et al., Dexamethasone and IL-10 stimulate glucocorticoid-induced leucine zipper synthesis by human mast cells, Allergy, vol.86, issue.7, pp.886-890, 2006.
DOI : 10.1111/j.1398-9995.2004.00587.x

URL : https://hal.archives-ouvertes.fr/hal-00282496

L. Ellestad, S. Malkiewicz, H. Guthrie, G. Welch, and T. Porter, Expression and regulation of glucocorticoid-induced leucine zipper in the developing anterior pituitary gland, Journal of Molecular Endocrinology, vol.42, issue.2, pp.171-183, 2009.
DOI : 10.1677/JME-08-0066

M. Robert-nicoud, M. Flahaut, J. Elalouf, M. Nicod, M. Salinas et al., Transcriptome of a mouse kidney cortical collecting duct cell line: Effects of aldosterone and vasopressin, Proceedings of the National Academy of Sciences, vol.98, issue.5, pp.2712-2716, 2001.
DOI : 10.1073/pnas.051603198

S. Tynan, S. Lundeen, and G. Allan, Cell type-specific bidirectional regulation of the glucocorticoid-induced leucine zipper (GILZ) gene by estrogen, The Journal of Steroid Biochemistry and Molecular Biology, vol.91, issue.4-5, pp.225-239, 2004.
DOI : 10.1016/j.jsbmb.2004.05.002

E. Ayroldi, O. Zollo, A. Macchiarulo, D. Marco, B. Marchetti et al., Glucocorticoid-Induced Leucine Zipper Inhibits the Raf-Extracellular Signal-Regulated Kinase Pathway by Binding to Raf-1, Molecular and Cellular Biology, vol.22, issue.22, pp.7929-7941, 2002.
DOI : 10.1128/MCB.22.22.7929-7941.2002

P. Mittelstadt and J. Ashwell, Inhibition of AP-1 by the Glucocorticoid-inducible Protein GILZ, Journal of Biological Chemistry, vol.276, issue.31, pp.29603-29610, 2001.
DOI : 10.1074/jbc.M101522200

M. Asselin-labat, M. David, A. Biola-vidamment, D. Lecoeuche, M. Zennaro et al., GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis, Blood, vol.104, issue.1, pp.215-223, 2004.
DOI : 10.1182/blood-2003-12-4295

K. Grugan, C. Ma, S. Singhal, N. Krett, and S. Rosen, Dual regulation of glucocorticoid-induced leucine zipper (GILZ) by the glucocorticoid receptor and the PI3-kinase/AKT pathways in multiple myeloma, The Journal of Steroid Biochemistry and Molecular Biology, vol.110, issue.3-5, pp.244-254, 2008.
DOI : 10.1016/j.jsbmb.2007.11.003

P. Bachmann, R. Gorman, R. Papa, J. Bardell, J. Ford et al., Divergent Mechanisms of Glucocorticoid Resistance in Experimental Models of Pediatric Acute Lymphoblastic Leukemia, Cancer Research, vol.67, issue.9, pp.4482-4490, 2007.
DOI : 10.1158/0008-5472.CAN-06-4244

R. Blind and M. Garabedian, Differential recruitment of glucocorticoid receptor phospho-isoforms to glucocorticoid-induced genes, The Journal of Steroid Biochemistry and Molecular Biology, vol.109, issue.1-2, pp.150-157, 2008.
DOI : 10.1016/j.jsbmb.2008.01.002

W. Chen, I. Rogatsky, and M. Garabedian, MED14 and MED1 Differentially Regulate Target-Specific Gene Activation by the Glucocorticoid Receptor, Molecular Endocrinology, vol.20, issue.3, pp.560-572, 2006.
DOI : 10.1210/me.2005-0318

M. Khouja, M. Baekelandt, J. Nesland, and R. Holm, The Clinical Importance of Ki-67, p16, p14, and p57 Expression in Patients With Advanced Ovarian Carcinoma, International Journal of Gynecological Pathology, vol.26, issue.4, pp.418-425, 2007.
DOI : 10.1097/pgp.0b013e31804216a0

R. Guo, Y. Qiao, Y. Zhou, L. Li, H. Shi et al., Increased staining for phosphorylated AKT and nuclear factor-??B p65 and their relationship with prognosis in epithelial ovarian cancer, Pathology International, vol.119, issue.12, pp.749-756, 2008.
DOI : 10.1111/j.1440-1827.2008.02306.x

D. Altomare, H. Wang, K. Skele, D. Rienzo, A. Klein-szanto et al., AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth, Oncogene, vol.23, issue.34, pp.5853-5857, 2004.
DOI : 10.1038/sj.onc.1207721

N. Gao, D. Flynn, Z. Zhang, X. Zhong, V. Walker et al., G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells, AJP: Cell Physiology, vol.287, issue.2, pp.281-291, 2004.
DOI : 10.1152/ajpcell.00422.2003

T. Franke, PI3K/Akt: getting it right matters, Oncogene, vol.19, issue.50, pp.6473-6488, 2008.
DOI : 10.1083/jcb.151.3.483

Y. Mitsuuchi, S. Johnson, M. Selvakumaran, S. Williams, T. Hamilton et al., The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel, Cancer Res, vol.60, pp.5390-5394, 2000.

C. Sherr and J. Roberts, CDK inhibitors: positive and negative regulators of G1-phase progression, Genes & Development, vol.13, issue.12, pp.1501-1512, 1999.
DOI : 10.1101/gad.13.12.1501

R. Weinberg, The retinoblastoma protein and cell cycle control, Cell, vol.81, issue.3, pp.323-330, 1995.
DOI : 10.1016/0092-8674(95)90385-2

H. Naora and D. Montell, Ovarian Cancer Metastasis: Integrating insights from disparate model organisms, Nature Reviews Cancer, vol.128, issue.5, pp.355-366, 2005.
DOI : 10.1016/j.devcel.2004.05.020

M. Shih-ie and R. Kurman, Ovarian Tumorigenesis, The American Journal of Pathology, vol.164, issue.5, pp.1511-1518, 2004.
DOI : 10.1016/S0002-9440(10)63708-X

D. Schwartz, S. Kardia, K. Shedden, R. Kuick, G. Michailidis et al., Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas, Cancer Res, vol.62, pp.4722-4729, 2002.

K. Zorn, T. Bonome, L. Gangi, G. Chandramouli, C. Awtrey et al., Gene Expression Profiles of Serous, Endometrioid, and Clear Cell Subtypes of Ovarian and Endometrial Cancer, Clinical Cancer Research, vol.11, issue.18, pp.6422-6430, 2005.
DOI : 10.1158/1078-0432.CCR-05-0508

M. Kobel, S. Kalloger, N. Boyd, S. Mckinney, E. Mehl et al., Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies, PLoS Medicine, vol.123, issue.12, p.232, 2008.
DOI : 10.1371/journal.pmed.0050232.st004

L. Shayesteh, Y. Lu, W. Kuo, R. Baldocchi, T. Godfrey et al., PIK3CA is implicated as an oncogene in ovarian cancer, Nature Genetics, vol.21, issue.1, pp.99-102, 1999.
DOI : 10.1038/5042

D. Altomare and J. Testa, Perturbations of the AKT signaling pathway in human cancer, Oncogene, vol.11, issue.50, pp.7455-7464, 2005.
DOI : 10.1053/sonc.2002.34057

E. Ayroldi, O. Zollo, A. Bastianelli, C. Marchetti, M. Agostini et al., GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling, Journal of Clinical Investigation, vol.117, issue.6, pp.1605-1615, 2007.
DOI : 10.1172/JCI30724DS1

T. Abbas and A. Dutta, p21 in cancer: intricate networks and multiple activities, Nature Reviews Cancer, vol.23, issue.6, pp.21400-414, 2009.
DOI : 10.1038/nrc2657

R. Muise-helmericks, H. Grimes, A. Bellacosa, S. Malstrom, P. Tsichlis et al., Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway, Journal of Biological Chemistry, vol.273, issue.45, pp.29864-29872, 1998.
DOI : 10.1074/jbc.273.45.29864

J. Liang and J. Slingerland, Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression, Cell Cycle, vol.2, issue.4, pp.339-345, 2003.
DOI : 10.4161/cc.2.4.433

W. Zhang, N. Yang, and X. Shi, Regulation of Mesenchymal Stem Cell Osteogenic Differentiation by Glucocorticoid-induced Leucine Zipper (GILZ), Journal of Biological Chemistry, vol.283, issue.8, pp.4723-4729, 2008.
DOI : 10.1074/jbc.M704147200

E. Nam and Y. Kim, Alteration of cell-cycle regulation in epithelial ovarian cancer, International Journal of Gynecological Cancer, vol.18, issue.6, pp.1169-1182, 2008.
DOI : 10.1111/j.1525-1438.2008.01191.x

I. Vivanco and C. Sawyers, The phosphatidylinositol 3-Kinase???AKT pathway in human cancer, Nature Reviews Cancer, vol.2, issue.7, pp.489-501, 2002.
DOI : 10.1038/nrc839

J. Alao, The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention, Molecular Cancer, vol.6, issue.1, p.24, 2007.
DOI : 10.1186/1476-4598-6-24

A. Bali, O. Brien, P. Edwards, L. Sutherland, R. Hacker et al., Cyclin D1, p53, and p21Waf1/Cip1 Expression Is Predictive of Poor Clinical Outcome in Serous Epithelial Ovarian Cancer, Clinical Cancer Research, vol.10, issue.15, pp.5168-5177, 2004.
DOI : 10.1158/1078-0432.CCR-03-0751

Y. Shimizu, S. Kamoi, S. Amada, F. Akiyama, and S. Silverberg, Toward the development of a universal grading system for ovarian epithelial carcinoma, Cancer, vol.32, issue.5, pp.893-901, 1998.
DOI : 10.1002/(SICI)1097-0142(19980301)82:5<893::AID-CNCR14>3.0.CO;2-W

T. Chan, S. Rittenhouse, and P. Tsichlis, AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation, Annual Review of Biochemistry, vol.68, issue.1, pp.965-1014, 1999.
DOI : 10.1146/annurev.biochem.68.1.965

A. Noske, A. Kaszubiak, W. Weichert, C. Sers, S. Niesporek et al., Specific inhibition of AKT2 by RNA interference results in reduction of ovarian cancer cell proliferation: Increased expression of AKT in advanced ovarian cancer, Cancer Letters, vol.246, issue.1-2, pp.190-200, 2007.
DOI : 10.1016/j.canlet.2006.02.018

M. Sun, G. Wang, J. Paciga, R. Feldman, Z. Yuan et al., AKT1/PKB?? Kinase Is Frequently Elevated in Human Cancers and Its Constitutive Activation Is Required for Oncogenic Transformation in NIH3T3 Cells, The American Journal of Pathology, vol.159, issue.2, pp.431-437, 2001.
DOI : 10.1016/S0002-9440(10)61714-2

S. Runz, S. Keller, C. Rupp, A. Stoeck, Y. Issa et al., Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM, Gynecologic Oncology, vol.107, issue.3, pp.563-571, 2007.
DOI : 10.1016/j.ygyno.2007.08.064

M. Belot, L. Abdennebi-najar, F. Gaudin, E. D. Machelon, and V. , Progesterone increases csk homologous kinase in HMC-1560 human mast cells and reduces cell proliferation, Journal of Cellular Biochemistry, vol.6, issue.5, pp.1271-1280, 2007.
DOI : 10.1002/jcb.21357

L. Sansregret, B. Goulet, R. Harada, B. Wilson, L. Leduy et al., The p110 Isoform of the CDP/Cux Transcription Factor Accelerates Entry into S Phase, Molecular and Cellular Biology, vol.26, issue.6, pp.2441-2455, 2006.
DOI : 10.1128/MCB.26.6.2441-2455.2006