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Conference Papers Year : 2010

Progeria, a model for accelerated aging exhibited by HIV patients?

Pierre Cau
  • Function : Author
Génétique Médicale et Génomique Fonctionnelle

Abstract

To confirm, among HIV1-infected patients, data from in vitro studies showing that antiretroviral therapies (ART) induce an accelerated aging through the same mechanism than genetic laminopathies (progeria) and «physiological » aging, i.e. through the synthesis and persistence of farnesylated prelamin A. The perspective is to minimize ART side effects using the same drug combination yet given to treat progeria children in Marseille.

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Infectious diseases
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https://www.hal.inserm.fr/inserm-00663755

Submitted on : Friday, January 27, 2012-2:22:16 PM

Last modification on : Friday, March 24, 2023-2:52:55 PM

Long-term archiving on: Saturday, April 28, 2012-2:32:27 AM

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inserm-00663755 , version 1 (27-01-2012)

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  • HAL Id : inserm-00663755 , version 1

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Pierre Cau. Progeria, a model for accelerated aging exhibited by HIV patients?. 16th International Symposium on HIV and Emerging Infectious Diseases, ISHEID, Mar 2010, Marseille, France. pp.I29. ⟨inserm-00663755⟩

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