Skip to Main content Skip to Navigation
Journal articles

Current concepts regarding the HTLV-1 receptor complex.

Abstract : The identity of the Human T lymphotropic Virus type 1 (HTLV-1) receptor remained an unsolved puzzle for two decades, until the recent demonstration that three molecules, Glucose Transporter 1, Neuropilin-1 and Heparan Sulfate Proteoglycans are involved in HTLV-1 binding and entry. Despite these advances, several questions remain unanswered, including the precise role of each of these molecules during virus entry. In light of the most recent data, we propose a model of the HTLV-1 receptor complex and discuss its potential impact on HTLV-1 infection.
Document type :
Journal articles
Complete list of metadata

Cited literature [92 references]  Display  Hide  Download
Contributor : Ed. BMC Connect in order to contact the contributor
Submitted on : Friday, January 27, 2012 - 2:13:33 PM
Last modification on : Wednesday, April 13, 2022 - 3:40:04 AM
Long-term archiving on: : Monday, November 19, 2012 - 3:06:23 PM


Publisher files allowed on an open archive




David Ghez, yves Lepelletier, Kathryn Jones, Claudine Pique, Olivier Hermine. Current concepts regarding the HTLV-1 receptor complex.. Retrovirology, BioMed Central, 2010, 7 (1), pp.99. ⟨10.1186/1742-4690-7-99⟩. ⟨inserm-00663710⟩



Record views


Files downloads