C. Brun-buisson, C. Minelli, G. Bertolini, L. Brazzi, J. Pimentel et al., ALIVE Study Group: Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study, Intensive Care Med, vol.30, pp.51-61, 2004.

G. Bernard, A. Artigas, K. Brigham, J. Carlet, K. Falke et al., The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination., American Journal of Respiratory and Critical Care Medicine, vol.149, issue.3, pp.818-824, 1994.
DOI : 10.1164/ajrccm.149.3.7509706

J. Phua, J. Badia, N. Adhikari, J. Friedrich, R. Fowler et al., Has Mortality from Acute Respiratory Distress Syndrome Decreased over Time?, American Journal of Respiratory and Critical Care Medicine, vol.179, issue.3, pp.220-227, 2009.
DOI : 10.1164/rccm.200805-722OC

L. Ware and M. Matthay, The Acute Respiratory Distress Syndrome, New England Journal of Medicine, vol.342, issue.18, pp.1334-1349, 2000.
DOI : 10.1056/NEJM200005043421806

V. Combes, T. Taylor, I. Juhan-vague, J. Mège, J. Mwenechanya et al., Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma, JAMA, vol.291, pp.2542-2544, 2004.

R. Nieuwland, R. Berckmans, S. Mcgregor, A. Böing, F. Romijn et al., Sturk A: Cellular origin and procoagulant properties of microparticles in meningococcal sepsis, Blood, vol.95, pp.930-935, 2000.

H. Ogura, H. Tanaka, T. Koh, K. Fujita, S. Fujimi et al., Enhanced Production of Endothelial Microparticles With Increased Binding to Leukocytes in Patients With Severe Systemic Inflammatory Response Syndrome, The Journal of Trauma: Injury, Infection, and Critical Care, vol.56, issue.4, pp.823-830, 2004.
DOI : 10.1097/01.TA.0000084517.39244.46

O. Morel, F. Toti, B. Hugel, B. Bakouboula, L. Camoin-jau et al., Procoagulant Microparticles: Disrupting the Vascular Homeostasis Equation?, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.26, issue.12, pp.2594-2604, 2006.
DOI : 10.1161/01.ATV.0000246775.14471.26

R. Munford and J. Pugin, Normal Responses to Injury Prevent Systemic Inflammation and Can Be Immunosuppressive, American Journal of Respiratory and Critical Care Medicine, vol.163, issue.2, pp.316-321, 2001.
DOI : 10.1164/ajrccm.163.2.2007102

L. Gall, J. Lemeshow, S. Saulnier, and F. , A New Simplified Acute Physiology Score (SAPS II) Based on a European/North American Multicenter Study, JAMA: The Journal of the American Medical Association, vol.270, issue.24, pp.2957-2963, 1993.
DOI : 10.1001/jama.1993.03510240069035

. Guervilly, Critical Care, pp.31-31, 2011.

J. Murray, M. Matthay, J. Luce, and M. Flick, An Expanded Definition of the Adult Respiratory Distress Syndrome, American Review of Respiratory Disease, vol.138, issue.3, pp.720-723, 1988.
DOI : 10.1164/ajrccm/138.3.720

J. Vincent, R. Moreno, J. Takala, S. Willatts, D. Mendonça et al., The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure, Intensive Care Medicine, vol.21, issue.7, pp.707-710, 1996.
DOI : 10.1007/BF01709751

R. Bone, R. Balk, F. Cerra, R. Dellinger, A. Fein et al., Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis, The ACCP/SCCM Consensus Conference Committee, pp.1644-1655, 1992.
DOI : 10.1378/chest.101.6.1644

S. Rennard, G. Basset, D. Lecossier, O. Donnell, K. Pinkston et al., Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution, J Appl Physiol, vol.60, pp.532-538, 1986.

A. Kobayashi, S. Hashimoto, K. Kooguchi, Y. Kitamura, H. Onodera et al., Expression of Inducible Nitric Oxide Synthase and Inflammatory Cytokines in Alveolar Macrophages of ARDS Following Sepsis, Chest, vol.113, issue.6, pp.1632-1639, 1998.
DOI : 10.1378/chest.113.6.1632

G. Al-massarani, H. Vacher-coponat, P. Paul, L. Arnaud, A. Loundou et al., Kidney Transplantation Decreases the Level and Procoagulant Activity of Circulating Microparticles, American Journal of Transplantation, vol.307, issue.Pt 1, pp.550-557, 2009.
DOI : 10.1111/j.1600-6143.2008.02532.x

S. Fujimi, H. Ogura, H. Tanaka, T. Koh, H. Hosotsubo et al., Increased Production of Leukocyte Microparticles with Enhanced Expression of Adhesion Molecules from Activated Polymorphonuclear Leukocytes in Severely Injured Patients, The Journal of Trauma: Injury, Infection, and Critical Care, vol.54, issue.1, pp.114-119, 2003.
DOI : 10.1097/00005373-200301000-00014

N. Morel, O. Morel, L. Petit, B. Hugel, J. Cochard et al., Generation of Procoagulant Microparticles in Cerebrospinal Fluid and Peripheral Blood After Traumatic Brain Injury, The Journal of Trauma: Injury, Infection, and Critical Care, vol.64, issue.3, pp.698-704, 2008.
DOI : 10.1097/TA.0b013e31816493ad

A. Soriano, W. Jy, J. Chirinos, M. Valdivia, H. Velasquez et al., Levels of endothelial and platelet microparticles and their interactions with leukocytes negatively correlate with organ dysfunction and predict mortality in severe sepsis, Critical Care Medicine, vol.33, issue.11, pp.2540-2546, 2005.
DOI : 10.1097/01.CCM.0000186414.86162.03

J. Bastarache, R. Fremont, J. Kropski, F. Bossert, and L. Ware, Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome, AJP: Lung Cellular and Molecular Physiology, vol.297, issue.6, pp.1035-1041, 2009.
DOI : 10.1152/ajplung.00214.2009

T. Nuckton, J. Alonso, R. Kallet, B. Daniel, J. Pittet et al., Pulmonary Dead-Space Fraction as a Risk Factor for Death in the Acute Respiratory Distress Syndrome, New England Journal of Medicine, vol.346, issue.17, pp.1281-1286, 2002.
DOI : 10.1056/NEJMoa012835

F. Jardin and A. Vieillard-baron, Is there a??safe plateau pressure in ARDS? The right heart only knows, Intensive Care Medicine, vol.31, issue.3, pp.444-447, 2007.
DOI : 10.1007/s00134-007-0552-z

N. Ikuta, H. Taniguchi, Y. Kondoh, K. Takagi, and T. Hayakawa, Sustained High Levels of Circulatory Interleukin-8 are Associated with a Poor Outcome in Patients with Adult Respiratory Distress Syndrome., Internal Medicine, vol.35, issue.11, pp.855-860, 1996.
DOI : 10.2169/internalmedicine.35.855

G. Meduri, G. Kohler, S. Headley, E. Tolley, F. Stentz et al., Inflammatory Cytokines in the BAL of Patients With ARDS, Chest, vol.108, issue.5, pp.1303-1314, 1995.
DOI : 10.1378/chest.108.5.1303

R. Hotchkiss and I. Karl, The Pathophysiology and Treatment of Sepsis, New England Journal of Medicine, vol.348, issue.2, pp.138-150, 2003.
DOI : 10.1056/NEJMra021333

O. Gasser and J. Schifferli, Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis, Blood, vol.104, issue.8, pp.2543-2548, 2004.
DOI : 10.1182/blood-2004-01-0361

J. Dalli, L. Norling, D. Renshaw, D. Cooper, K. Leung et al., Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles, Blood, vol.112, issue.6, pp.2512-2519, 2008.
DOI : 10.1182/blood-2008-02-140533

H. Mostefai, F. Meziani, M. Mastronardi, A. Agouni, C. Heymes et al., Circulating Microparticles from Patients with Septic Shock Exert Protective Role in Vascular Function, American Journal of Respiratory and Critical Care Medicine, vol.178, issue.11, pp.1148-1155, 2008.
DOI : 10.1164/rccm.200712-1835OC

URL : https://hal.archives-ouvertes.fr/hal-01389216

D. Mutschler, A. Larsson, S. Basu, A. Nordgren, and M. Eriksson, Effects of mechanical ventilation on platelet microparticles in bronchoalveolar lavage fluid, Thrombosis Research, vol.108, issue.4, pp.215-220, 2002.
DOI : 10.1016/S0049-3848(03)00005-7

S. Robert, P. Poncelet, R. Lacroix, L. Arnaud, L. Giraudo et al., Standardization of platelet-derived microparticle counting using calibrated beads and a Cytomics FC500 routine flow cytometer: a first step towards multicenter studies?, Journal of Thrombosis and Haemostasis, vol.16, issue.1, pp.190-197, 2009.
DOI : 10.1111/j.1538-7836.2008.03200.x