M. Berridge, Inositol Trisphosphate and Calcium Signaling, Annals of the New York Academy of Sciences, vol.246, issue.1 Receptor Acti, pp.31-43, 1995.
DOI : 10.1016/0092-8674(92)90409-6

S. Feske, H. Okamura, P. Hogan, and A. Rao, Ca2+/calcineurin signalling in cells of the immune system, Biochemical and Biophysical Research Communications, vol.311, issue.4, pp.1117-1132, 2003.
DOI : 10.1016/j.bbrc.2003.09.174

S. Chung, T. Mcdonald, and P. Gardner, Inhibition by SK&F 96365 of Ca2+ current, IL-2 production and activation in T lymphocytes, British Journal of Pharmacology, vol.90, issue.3, pp.861-868, 1994.
DOI : 10.1111/j.1476-5381.1994.tb17072.x

S. Feske, Y. Gwack, M. Prakriya, S. Srikanth, S. Puppel et al., A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function, Nature, vol.25, issue.7090, pp.179-185, 2006.
DOI : 10.1038/nature04702

C. Peinelt, M. Vig, D. Koomoa, A. Beck, M. Nadler et al., Amplification of CRAC current by STIM1 and CRACM1 (Orai1), Nature Cell Biology, vol.465, issue.7, pp.771-773, 2006.
DOI : 10.1085/jgp.107.5.597

R. Lewis, The molecular choreography of a store-operated calcium channel, Nature, vol.7, issue.7133, pp.284-287, 2007.
DOI : 10.1038/nature05637

J. Mercer, W. Dehaven, J. Smyth, B. Wedel, R. Boyles et al., Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1, Journal of Biological Chemistry, vol.281, issue.34, pp.24979-24990, 2006.
DOI : 10.1074/jbc.M604589200

Y. Gwack, S. Srikanth, S. Feske, F. Cruz-guilloty, M. Oh-hora et al., Biochemical and Functional Characterization of Orai Proteins, Journal of Biological Chemistry, vol.282, issue.22, pp.16232-16243, 2007.
DOI : 10.1074/jbc.M609630200

I. Derler, R. Fritsch, R. Schindl, and C. Romanin, CRAC inhibitors: identification and potential. Expert Opinion Drug Discovery, pp.787-800, 2008.

Y. Huang, K. Hoebe, and K. Sauer, New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B, Expert Opinion on Therapeutic Targets, vol.14, issue.4, pp.391-413, 2008.
DOI : 10.1073/pnas.0402803101

Z. Sweeney, A. Minatti, D. Button, and S. Patrick, Small-Molecule Inhibitors of Store-Operated Calcium Entry, ChemMedChem, vol.319, issue.5, 2009.
DOI : 10.1002/cmdc.200800452

T. Maruyama, T. Kanaji, S. Nakade, T. Kanno, and K. Mikoshiba, 2APB, 2-Aminoethoxydiphenyl Borate, a Membrane-Penetrable Modulator of Ins(1,4,5)P3-Induced Ca2+ Release, Journal of Biochemistry, vol.122, issue.3, pp.498-505, 1997.
DOI : 10.1093/oxfordjournals.jbchem.a021780

J. Bilmen, L. Wootton, R. Godfrey, O. Smart, and F. Michelangeli, Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB). 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites

L. Missiaen, G. Callewaert, D. Smedt, H. Parys, and J. , 2-Aminoethoxydiphenyl borate affects the inositol 1,4,5-trisphosphate receptor, the intracellular Dellis et al, BMC Pharmacology, vol.11, issue.1, 2011.

C. Peppiatt, T. Collins, L. Mackenzie, S. Conway, A. Holmes et al., 2-Aminoethoxydiphenyl borate (2-APB) antagonises inositol 1,4,5-trisphosphate-induced calcium release, inhibits calcium pumps and has a use-dependent and slowly reversible action on store-operated calcium entry channels, Cell Calcium, vol.34, issue.1, pp.97-108, 2003.
DOI : 10.1016/S0143-4160(03)00026-5

J. Kukkonen, P. Lund, and K. Akerman, 2-aminoethoxydiphenyl borate reveals heterogeneity in receptor-activated Ca2+discharge and store-operated Ca2+influx, Cell Calcium, vol.30, issue.2, pp.117-129, 2001.
DOI : 10.1054/ceca.2001.0219

M. Prakriya and R. Lewis, receptors, The Journal of Physiology, vol.105, issue.1, pp.3-19, 2001.
DOI : 10.1111/j.1469-7793.2001.t01-1-00003.x

H. Ma, K. Venkatachalam, J. Parys, and D. Gill, Modification of Store-operated Channel Coupling and Inositol Trisphosphate Receptor Function by 2-Aminoethoxydiphenyl Borate in DT40 Lymphocytes, Journal of Biological Chemistry, vol.277, issue.9, pp.6915-6922, 2002.
DOI : 10.1074/jbc.M107755200

M. Chung, H. Lee, A. Mizuno, M. Suzuki, and M. Caterina, 2-Aminoethoxydiphenyl Borate Activates and Sensitizes the Heat-Gated Ion Channel TRPV3, Journal of Neuroscience, vol.24, issue.22, pp.5177-5182, 2004.
DOI : 10.1523/JNEUROSCI.0934-04.2004

H. Hu, Q. Gu, C. Wang, C. Colton, J. Tang et al., 2-Aminoethoxydiphenyl Borate Is a Common Activator of TRPV1, TRPV2, and TRPV3, Journal of Biological Chemistry, vol.279, issue.34, pp.35741-35748, 2004.
DOI : 10.1074/jbc.M404164200

J. Lievremont, G. Bird, J. Putney, and . Jr, Mechanism of Inhibition of TRPC Cation Channels by 2-Aminoethoxydiphenylborane, Molecular Pharmacology, vol.68, pp.758-762, 2005.
DOI : 10.1124/mol.105.012856

Y. Dobrydneva, C. Abelt, B. Dovel, C. Thadigiri, and R. Williams, Blackmore PF: 2-aminoethoxydiphenyl borate as a prototype drug for a group of structurally related calcium channel blockers in human platelets, Mol Pharmacol, vol.69, pp.247-256, 2006.

Y. Dobrydneva and P. Blackmore, 2-Aminoethoxydiphenyl borate directly inhibits store-operated calcium entry channels in human platelets, Mol Pharmacol, vol.60, pp.541-552, 2001.

H. Zhou, H. Iwasaki, T. Nakamura, K. Nakamura, T. Maruyama et al., 2-Aminoethyl diphenylborinate analogues: Selective inhibition for store-operated Ca2+ entry, Biochemical and Biophysical Research Communications, vol.352, issue.2, pp.277-282, 2007.
DOI : 10.1016/j.bbrc.2006.10.174

A. Suzuki, S. Ozaki, J. Goto, and K. Mikoshiba, Synthesis of bisboron compounds and their strong inhibitory activity on store-operated calcium entry, Bioorganic & Medicinal Chemistry Letters, vol.20, issue.4, pp.1395-1398, 2010.
DOI : 10.1016/j.bmcl.2009.12.108

O. Dellis, S. Gangloff, M. Paulais, D. Tondelier, J. Rona et al., Inhibition of the Calcium Release-activated Calcium (CRAC) Current in Jurkat T Cells by the HIV-1 Envelope Protein gp160, Journal of Biological Chemistry, vol.277, issue.8, pp.6044-6050, 2002.
DOI : 10.1074/jbc.M111831200

G. Bird, W. Dehaven, J. Smyth, J. Putney, and . Jr, Methods for studying storeoperated calcium entry, pp.204-212, 2008.

A. Lis, C. Peinelt, A. Beck, S. Parvez, M. Monteilh-zoller et al., CRACM1, CRACM2, and CRACM3 Are Store-Operated Ca2+ Channels with Distinct Functional Properties, Current Biology, vol.17, issue.9, pp.794-800, 2007.
DOI : 10.1016/j.cub.2007.03.065

H. Sugawara, M. Kurosaki, M. Takata, and T. Kurosaki, Genetic evidence for involvement of type 1,type 2and type 3inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor, The EMBO Journal, vol.16, issue.11, pp.3078-3088, 1997.
DOI : 10.1093/emboj/16.11.3078

T. Mccormack, W. Baumeister, L. Grenier, C. Moomaw, L. Plamondon et al., Active Site-directed Inhibitors of Rhodococcus 20 S Proteasome: KINETICS AND MECHANISM, Journal of Biological Chemistry, vol.272, issue.42, pp.26103-26109, 1997.
DOI : 10.1074/jbc.272.42.26103

M. Chung, A. Guler, and M. Caterina, Biphasic Currents Evoked by Chemical or Thermal Activation of the Heat-gated Ion Channel, TRPV3, Journal of Biological Chemistry, vol.280, issue.16, pp.15928-15941, 2005.
DOI : 10.1074/jbc.M500596200

V. Juvin, A. Penna, J. Chemin, Y. Lin, and F. Rassendren, Pharmacological Characterization and Molecular Determinants of the Activation of Transient Receptor Potential V2 Channel Orthologs by 2-Aminoethoxydiphenyl Borate, Molecular Pharmacology, vol.72, issue.5, pp.1258-1268, 2007.
DOI : 10.1124/mol.107.037044
URL : https://hal.archives-ouvertes.fr/inserm-00320694

S. Feske, J. Giltnane, R. Dolmetsch, L. Staudt, and A. Rao, Corrigendum: Gene regulation mediated by calcium signals in T lymphocytes, Nature Immunology, vol.165, issue.3, pp.316-324, 2001.
DOI : 10.1038/ni0308-328

R. Motiani, I. Abdullaev, and M. Trebak, A Novel Native Store-operated Calcium Channel Encoded by Orai3: SELECTIVE REQUIREMENT OF Orai3 VERSUS Orai1 IN ESTROGEN RECEPTOR-POSITIVE VERSUS ESTROGEN RECEPTOR-NEGATIVE BREAST CANCER CELLS, Journal of Biological Chemistry, vol.285, issue.25, 2010.
DOI : 10.1074/jbc.M110.102582

I. Ambudkar, H. Ong, X. Liu, B. Bandyopadhyay, and K. Cheng, TRPC1: The link between functionally distinct store-operated calcium channels, Cell Calcium, vol.42, issue.2, pp.213-223, 2007.
DOI : 10.1016/j.ceca.2007.01.013

Y. Liao, C. Erxleben, E. Yildirim, J. Abramowitz, D. Armstrong et al., Orai proteins interact with TRPC channels and confer responsiveness to store depletion, Proceedings of the National Academy of Sciences, vol.104, issue.11, pp.4682-4687, 2007.
DOI : 10.1073/pnas.0611692104

D. Varga-szabo, K. Authi, A. Braun, M. Bender, A. Ambily et al., Store-operated Ca2+ entry in platelets occurs independently of transient receptor potential (TRP) C1, Pfl??gers Archiv - European Journal of Physiology, vol.254, issue.Pt 3, pp.377-387, 2008.
DOI : 10.1007/s00424-008-0531-4

J. Soboloff, M. Spassova, X. Tang, T. Hewavitharana, W. Xu et al., Orai1 and STIM Reconstitute Store-operated Calcium Channel Function, Journal of Biological Chemistry, vol.281, issue.30, pp.20661-20665, 2006.
DOI : 10.1074/jbc.C600126200

N. Scrimgeour, T. Litjens, L. Ma, G. Barritt, and G. Rychkov, Properties of Orai1 mediated store-operated current depend on the expression levels of STIM1 and Orai1 proteins, The Journal of Physiology, vol.270, issue.12, 2009.
DOI : 10.1113/jphysiol.2009.170662

P. Richardson, T. Hideshima, and K. Anderson, Bortezomib (PS-341): a novel, first-in-class proteasome inhibitor for the treatment of multiple myeloma and other cancers, Cancer Control, vol.10, pp.361-369, 2003.

A. Kisselev and A. Goldberg, Proteasome inhibitors: from research tools to drug candidates, Chemistry & Biology, vol.8, issue.8, pp.739-758, 2001.
DOI : 10.1016/S1074-5521(01)00056-4

J. Adams, M. Behnke, S. Chen, A. Cruickshank, L. Dick et al., Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids, Bioorganic & Medicinal Chemistry Letters, vol.8, issue.4, pp.333-338, 1998.
DOI : 10.1016/S0960-894X(98)00029-8

B. Walker and J. Lynas, Strategies for the inhibition of serine proteases, Cellular and Molecular Life Sciences, vol.58, issue.4, pp.596-624, 2001.
DOI : 10.1007/PL00000884

M. Spassova, J. Soboloff, L. He, W. Xu, M. Dziadek et al., STIM1 has a plasma membrane role in the activation of store-operated Ca2+ channels, Proceedings of the National Academy of Sciences, vol.103, issue.11, pp.4040-4045, 2006.
DOI : 10.1073/pnas.0510050103

C. Peinelt, A. Lis, A. Beck, A. Fleig, and R. Penner, 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels, The Journal of Physiology, vol.90, issue.13, pp.3061-3073, 2008.
DOI : 10.1113/jphysiol.2008.151365

O. Dellis, A. Arbabian, J. Brouland, T. Kovacs, M. Rowe et al., Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus Latent Membrane Protein-1, Molecular Cancer, vol.8, issue.1, p.59, 2009.
DOI : 10.1186/1476-4598-8-59
URL : https://hal.archives-ouvertes.fr/inserm-00663619

G. Grynkiewicz, M. Poenie, and R. Tsien, A new generation of Ca2+ indicators with greatly improved fluorescence properties, J Biol Chem, vol.260, pp.3440-3450, 1985.

P. Nasmith and S. Grinstein, Phorbol ester-induced changes in cytoplasmic Ca2+ in human neutrophils Involvement of a pertussis toxin-sensitive G protein, J Biol Chem, vol.262, pp.13558-13566, 1987.