W. Marijt, M. Heemskerk, F. Kloosterboer, E. Goulmy, M. Kester et al., Hematopoiesis-restricted minor histocompatibility antigens HA-1- or HA-2-specific T cells can induce complete remissions of relapsed leukemia, Proceedings of the National Academy of Sciences, vol.100, issue.5, pp.2742-2747, 2003.
DOI : 10.1073/pnas.0530192100

R. Figlin, J. Thompson, R. Bukowski, N. Vogelzang, A. Novick et al., Tumor-Infiltrating Lymphocytes in Combination With Recombinant Interleukin-2 in Metastatic Renal Cell Carcinoma, Journal of Clinical Oncology, vol.17, issue.8, pp.2521-2529, 1999.
DOI : 10.1200/JCO.1999.17.8.2521

B. Dreno, J. Nguyen, A. Khammari, M. Pandolfino, M. Tessier et al., Randomized trial of adoptive transfer of melanoma tumor-infiltrating lymphocytes as adjuvant therapy for stage III melanoma, Cancer Immunology, Immunotherapy, vol.51, issue.10, pp.539-546, 2002.
DOI : 10.1007/s00262-002-0315-1

A. Khammari, J. Nguyen, M. Pandolfino, G. Quereux, A. Brocard et al., Long-term follow-up of patients treated by adoptive transfer of melanoma tumor-infiltrating lymphocytes as adjuvant therapy for stage III melanoma, Cancer Immunology, Immunotherapy, vol.12, issue.3, pp.1853-1860, 2007.
DOI : 10.1007/s00262-007-0340-1

L. Fang, A. Lonsdorf, and S. Hwang, Immunotherapy for Advanced Melanoma, Journal of Investigative Dermatology, vol.128, issue.11, pp.2596-2605, 2008.
DOI : 10.1038/jid.2008.101

S. Rosenberg and M. Dudley, Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes, Proceedings of the National Academy of Sciences, vol.101, issue.Supplement 2, pp.14639-14645, 2004.
DOI : 10.1073/pnas.0405730101

A. Khammari, N. Labarriere, V. Vignard, J. Nguyen, M. Pandolfino et al., Treatment of Metastatic Melanoma with Autologous Melan-A/Mart-1-Specific Cytotoxic T Lymphocyte Clones, Journal of Investigative Dermatology, vol.129, issue.12, pp.2835-2842, 2009.
DOI : 10.1038/jid.2009.144

F. Jotereau, M. Pandolfino, D. Boudart, E. Diez, B. Dreno et al., High-Fold Expansion of Human Cytotoxic T-Lymphocytes Specific for Autologous Melanoma Cells for Use in Immunotherapy, Journal of Immunotherapy, vol.10, issue.6, pp.405-411, 1991.
DOI : 10.1097/00002371-199112000-00003

M. Tessier, M. Pandolfino, F. Jotereau, D. Boudart, P. Litoux et al., Home therapy with autologous tumour-infiltrating lymphocytes and subcutaneous interleukin-2 in metastatic melanoma, European Journal of Cancer, vol.32, issue.4, pp.735-736, 1996.
DOI : 10.1016/0959-8049(95)00651-6

T. Jung, U. Schauer, C. Heusser, C. Neumann, and C. Rieger, Detection of intracellular cytokines by flow cytometry, Journal of Immunological Methods, vol.159, issue.1-2, pp.197-207, 1993.
DOI : 10.1016/0022-1759(93)90158-4

J. Klapper, A. Thomasian, D. Smith, G. Gorgas, J. Wunderlich et al., Single-pass, closed-system rapid expansion of lymphocyte cultures for adoptive cell therapy, Journal of Immunological Methods, vol.345, issue.1-2, pp.90-99, 2009.
DOI : 10.1016/j.jim.2009.04.009

V. Shankaran, H. Ikeda, A. Bruce, J. White, P. Swanson et al., IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity, Nature, vol.410, issue.6832, pp.1107-1111, 2001.
DOI : 10.1038/35074122

E. Chiao and S. Krown, Update on non???acquired immunodeficiency syndrome???defining malignancies, Current Opinion in Oncology, vol.15, issue.5, pp.389-397, 2003.
DOI : 10.1097/00001622-200309000-00008

A. Ladanyi, J. Kiss, B. Somlai, K. Gilde, Z. Fejos et al., Density of DC-LAMP+ mature dendritic cells in combination with activated T lymphocytes infiltrating primary cutaneous melanoma is a strong independent prognostic factor, Cancer Immunology, Immunotherapy, vol.154, issue.9, pp.1459-1469, 2007.
DOI : 10.1007/s00262-007-0286-3

X. Zhuang, X. Xia, C. Wang, F. Gao, N. Shan et al., A High Number of CD8+ T Cells Infiltrated in NSCLC Tissues is Associated With a Favorable Prognosis, Applied Immunohistochemistry & Molecular Morphology, vol.18, issue.1, pp.24-28, 2010.
DOI : 10.1097/PAI.0b013e3181b6a741

D. Zhang, P. Shankar, Z. Xu, B. Harnisch, G. Chen et al., Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic, Blood, vol.101, issue.1, pp.226-235, 2003.
DOI : 10.1182/blood-2002-03-0791

N. Labarriere, M. Pandolfino, N. Gervois, A. Khammari, M. Tessier et al., Therapeutic efficacy of melanoma-reactive TIL injected in stage III melanoma patients, Cancer Immunology, Immunotherapy, vol.51, issue.10, pp.532-538, 2002.
DOI : 10.1007/s00262-002-0313-3

L. Gattinoni, C. Klebanoff, D. Palmer, C. Wrzesinski, K. Kerstann et al., Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells, Journal of Clinical Investigation, vol.115, issue.6, pp.1616-1626, 2005.
DOI : 10.1172/JCI24480

L. Gattinoni, D. Powell, . Jr, S. Rosenberg, and N. Restifo, Adoptive immunotherapy for cancer: building on success, Nature Reviews Immunology, vol.115, issue.5, pp.383-393, 2006.
DOI : 10.1038/nri1842

M. Besser, R. Shapira-frommer, A. Treves, D. Zippel, O. Itzhaki et al., Clinical Responses in a Phase II Study Using Adoptive Transfer of Short-term Cultured Tumor Infiltration Lymphocytes in Metastatic Melanoma Patients, Clinical Cancer Research, vol.16, issue.9, pp.2646-2655, 2010.
DOI : 10.1158/1078-0432.CCR-10-0041

O. Itzhaki, E. Hovav, Y. Ziporen, D. Levy, A. Kubi et al., Establishment and Large-scale Expansion of Minimally cultured ???Young??? Tumor Infiltrating Lymphocytes for Adoptive Transfer Therapy, Journal of Immunotherapy, vol.0, issue.0, pp.212-220, 2011.
DOI : 10.1097/CJI.0b013e318209c94c

K. Tran, J. Zhou, K. Durflinger, M. Langhan, T. Shelton et al., Minimally Cultured Tumor-infiltrating Lymphocytes Display Optimal Characteristics for Adoptive Cell Therapy, Journal of Immunotherapy, vol.31, issue.8, pp.742-751, 2008.
DOI : 10.1097/CJI.0b013e31818403d5

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614999

N. Labarriere, N. Gervois, A. Bonnin, R. Bouquie, F. Jotereau et al., PBMC are as good a source of tumor-reactive T lymphocytes as TIL after selection by Melan-A/A2 multimer immunomagnetic sorting, Cancer Immunology, Immunotherapy, vol.162, issue.2, pp.185-195, 2008.
DOI : 10.1007/s00262-007-0361-9

URL : https://hal.archives-ouvertes.fr/inserm-00167752

C. Melief, Cancer Immunotherapy by Dendritic Cells, Immunity, vol.29, issue.3, pp.372-383, 2008.
DOI : 10.1016/j.immuni.2008.08.004

E. Huarte, J. Fisher, M. Turk, D. Mellinger, C. Foster et al., Ex vivo expansion of tumor specific lymphocytes with IL-15 and IL-21 for adoptive immunotherapy in melanoma, Cancer Letters, vol.285, issue.1, pp.80-88, 2009.
DOI : 10.1016/j.canlet.2009.05.003

. Zuliani, Value of large scale expansion of tumor infiltrating lymphocytes in a compartmentalised gas-permeable bag: interests for adoptive immunotherapy, Journal of Translational Medicine, vol.9, issue.1, p.63, 2011.
DOI : 10.1016/j.canlet.2009.05.003

URL : https://hal.archives-ouvertes.fr/inserm-00663657