Parathyroid hormone-related protein in human renal cell carcinoma, Cancer Letters, vol.240, issue.2, pp.170-182, 2006. ,
DOI : 10.1016/j.canlet.2005.08.020
Recent advances in targeted therapy for renal cell carcinoma, Current Opinion in Urology, vol.17, issue.5, pp.331-336, 2007. ,
DOI : 10.1097/MOU.0b013e3282c508e0
SYSTEMIC THERAPY FOR RENAL CELL CARCINOMA, The Journal of Urology, vol.163, issue.2, pp.408-417, 2000. ,
DOI : 10.1016/S0022-5347(05)67889-5
Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma, New England Journal of Medicine, vol.356, issue.2, pp.115-124, 2007. ,
DOI : 10.1056/NEJMoa065044
Sorafenib in advanced clear-cell renal-cell carcinoma, New Engl J Med, vol.356, pp.125-134, 2007. ,
Von Hippel-Lindau Syndrome, Cancer, vol.10, issue.S11, pp.2478-2485, 1999. ,
DOI : 10.1002/(SICI)1097-0142(19991201)86:11+<2478::AID-CNCR4>3.0.CO;2-5
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma, Clinical Cancer Research, vol.13, issue.2, pp.680-684, 2007. ,
DOI : 10.1158/1078-0432.CCR-06-1865
Two HIFs may be better than one, Cancer Cell, vol.1, issue.3, pp.211-213, 2002. ,
DOI : 10.1016/S1535-6108(02)00048-X
URL : http://doi.org/10.1016/s1535-6108(02)00048-x
The Phosphoinositide 3-Kinase/Akt Pathway: A New Target in Human Renal Cell Carcinoma Therapy, Cancer Research, vol.66, issue.10, pp.5130-5142, 2006. ,
DOI : 10.1158/0008-5472.CAN-05-1469
Targeting the Nuclear Factor-??B Rescue Pathway Has Promising Future in Human Renal Cell Carcinoma Therapy, Cancer Research, vol.67, issue.24, pp.11668-1176, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-0632
Inhibition of MAPK Kinase Signaling Pathways Suppressed Renal Cell Carcinoma Growth and Angiogenesis In vivo, Cancer Research, vol.68, issue.1, pp.81-88, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-5311
In vivo validation of PAX2 as a target for renal cancer therapy, Cancer Letters, vol.265, issue.1, pp.148-155, 2008. ,
DOI : 10.1016/j.canlet.2008.02.016
Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo, Journal of Clinical Investigation, vol.118, issue.1, pp.217-228, 2008. ,
DOI : 10.1172/JCI32086DS1
The Sonic Hedgehog Signaling Network in Development and Neoplasia, Advances in Anatomic Pathology, vol.14, issue.5, pp.344-352, 2007. ,
DOI : 10.1097/PAP.0b013e3180ca8a1d
Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation, Cancer Res, vol.62, pp.5867-5873, 2002. ,
Expression of cyclin D1, D3, E, and p27 in human renal cell carcinoma analysed by tissue microarray, British Journal of Cancer, vol.88, issue.9, pp.1417-1423, 2003. ,
DOI : 10.1038/sj.bjc.6600922
Expression of aquaporins and PAX-2 compared to CD10 and cytokeratin 7 in renal neoplasms: a tissue microarray study, Modern Pathology, vol.24, issue.4, pp.535-540, 2005. ,
DOI : 10.1038/modpathol.3800320
Hedgehog: functions and mechanisms, Genes & Development, vol.22, issue.18, pp.2454-2472, 2008. ,
DOI : 10.1101/gad.1693608
Control of Murine Kidney Development by Sonic Hedgehog and its GLI Effectors, Cell Cycle, vol.5, issue.13, pp.1426-1430, 2006. ,
DOI : 10.4161/cc.5.13.2928
Activation of the transcription factor Gli1 and the Sonic hedgehog signaling pathway in skin tumours, Nature, vol.389, pp.876-881, 1997. ,
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours, Nature, vol.425, issue.6960, pp.846-851, 2003. ,
DOI : 10.1038/nature01972
Cyclopamine-Mediated Hedgehog Pathway Inhibition Depletes Stem-Like Cancer Cells in Glioblastoma, Stem Cells, vol.66, issue.10, pp.2524-2533, 2007. ,
DOI : 10.1634/stemcells.2007-0166
HEDGEHOG-GLI1 Signaling Regulates Human Glioma Growth, Cancer Stem Cell Self-Renewal, and Tumorigenicity, Current Biology, vol.17, issue.2, pp.165-172, 2007. ,
DOI : 10.1016/j.cub.2006.11.033
Hypoxia-induced compensatory effect as related to Shh and HIF-1?? in ischemia embryo rat heart, Molecular and Cellular Biochemistry, vol.100, issue.1-2, pp.179-187, 2008. ,
DOI : 10.1007/s11010-008-9708-6
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways, Proceedings of the National Academy of Sciences, vol.104, issue.14, pp.5895-5900, 2007. ,
DOI : 10.1073/pnas.0700776104
Microvessel density in renal cell carcinoma: Lack of prognostic significance, Urology, vol.46, issue.1, pp.27-30, 1995. ,
DOI : 10.1016/S0090-4295(99)80153-8
Clinical Significance of Tumor Angiogenesis in Patients with Localized Renal Cell Carcinoma, Urology, vol.51, issue.5, pp.693-696, 1998. ,
DOI : 10.1016/S0090-4295(98)00019-3
Inverse correlation of microvessel density with metastasis and prognosis in renal cell carcinoma, International Journal of Urology, vol.95, issue.11, pp.948-953, 2004. ,
DOI : 10.1111/j.1442-2042.2004.00931.x
Endoglin (CD105) expression in angiogenesis of primary hepatocellular carcinomas: analysis using tissue microarrays and comparisons with CD34 and VEGF, Ann Clin Lab Sci, vol.37, pp.39-48, 2007. ,
Muscarinic Receptors Mediate Phospholipase C-dependent Activation of Protein Kinase B via Ca2+, ErbB3, and Phosphoinositide 3-Kinase in 1321N1 Astrocytoma Cells, Journal of Biological Chemistry, vol.277, issue.1, pp.338-344, 2002. ,
DOI : 10.1074/jbc.M108927200
The Cellular Basis of Kidney Development, Annual Review of Cell and Developmental Biology, vol.22, issue.1, pp.509-529, 2006. ,
DOI : 10.1146/annurev.cellbio.22.010305.104340
Regulation of Hh/Gli Signaling by Dual Ubiquitin Pathways, Cell Cycle, vol.5, issue.21, pp.2457-2463, 2006. ,
DOI : 10.4161/cc.5.21.3406
Nuclear Factor-??B Contributes to Hedgehog Signaling Pathway Activation through Sonic Hedgehog Induction in Pancreatic Cancer, Cancer Research, vol.66, issue.14, pp.7041-7049, 2006. ,
DOI : 10.1158/0008-5472.CAN-05-4588
The 1997 TNM classification of renal cell carcinoma revisited: the pendulum swings back, Current Opinion in Urology, vol.12, issue.5, pp.371-373, 2002. ,
DOI : 10.1097/00042307-200209000-00001
Parathyroid Hormone-Related Protein Is an Essential Growth Factor for Human Clear Cell Renal Carcinoma and a Target for the von Hippel-Lindau Tumor Suppressor Gene, Cancer Research, vol.64, issue.1, pp.180-188, 2004. ,
DOI : 10.1158/0008-5472.CAN-03-1968