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LF/(LF+HF) index in ventricular repolarization variability correlated and uncorrelated with heart rate variability.

Abstract : The purpose of this study, was to asses whether LF/(LF+HF) obtained from ventricular repolarization variability (VRV) reflects the state of sympathovagal balance. The VRV time series and heart rate variability (HRV) time series from seventy two electrocardiogram (ECG) records in four different autonomic nervous system (ANS) profiles (athletes, cardiac transplant patient, heart failure patients and normal subjects) were extracted. A dynamic linear parametric model was applied to separate the VRV in two parts, VRV correlated with HRV (VRV(r)) and VRV uncorrelated with HRV (VRV(u)). Spectral indices were obtained from HRV, VRV, VRV(u) and VRV(u) time series. Changes of these indicators from rest to tilt position were analyzed. Results showed that: i) only LF/(LF+HF) from HRV time series increases significantly from rest to tilt in all ANS profiles, this information could not be retrieved in the other three series (VRV, VRV (u) and VRV(u)) ii) LF/(LF+HF) index in HRV series are significantly different between normal subjects and heart failure patients, while cardiac transplant patients show a low coherence between HRV and VRV power spectra and iii) HF rhythm in VRV series seem to be related to the mechanical effect of respiration.
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https://www.hal.inserm.fr/inserm-00656264
Contributor : Lotfi Senhadji <>
Submitted on : Tuesday, January 3, 2012 - 6:44:33 PM
Last modification on : Monday, March 18, 2019 - 5:50:12 PM
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Miguel Altuve, Sara Wong, Gianfranco Passariello, Guy Carrault, Alfredo Hernández. LF/(LF+HF) index in ventricular repolarization variability correlated and uncorrelated with heart rate variability.. Conference proceedings : .. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, Institute of Electrical and Electronics Engineers (IEEE), 2006, 1, pp.1363-6. ⟨10.1109/IEMBS.2006.259821⟩. ⟨inserm-00656264⟩

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