Compact and highly stable quantum dots through optimized aqueous phase transfer - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Conference Papers Year : 2011

Compact and highly stable quantum dots through optimized aqueous phase transfer

Abstract

A large number of different approaches for the aqueous phase transfer of quantum dots have been proposed. Surface ligand exchange with small hydrophilic thiols, such as L-cysteine, yields the lowest hydrodynamic diameter. However, cysteine is prone to dimer formation, which limits colloidal stability. We demonstrate that precise pH control during aqueous phase transfer dramatically increases the colloidal stability of InP/ZnS quantum dots. Various bifunctional thiols have been applied. The formation of disulfides, strongly diminishing the fluorescence QY has been prevented through addition of appropriate reducing agents. Bright InP/ZnS quantum dots with a hydrodynamic diameter <10 nm and longterm stability have been obtained. Finally we present in vitro studies of the quantum dots functionalized with the cellpenetrating peptide maurocalcine
Fichier principal
Vignette du fichier
Tamang_2010_Compact_and_highly_Auteur.pdf (1.31 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

inserm-00647054 , version 1 (01-12-2011)

Identifiers

  • HAL Id : inserm-00647054 , version 1

Cite

Sudarsan Tamang, Grégory Beaune, Cathy Poillot, Michel de Waard, Isabelle Texier-Nogues, et al.. Compact and highly stable quantum dots through optimized aqueous phase transfer. Colloidal quantum dots/Nanocrystals for biomedical applications VI, Jan 2011, San Francisco-CA, United States. pp.79091B-79091B-6. ⟨inserm-00647054⟩
343 View
798 Download

Share

Gmail Facebook Twitter LinkedIn More