Validation of basal ganglia segmentation on a 3T MRI template

Claire Haegelen 1, * Nicolas Guizard 2 Pierrick Coupé 2 Florent Lalys 1 Pierre Jannin 1 Xavier Morandi 1 D. Louis Collins 2
* Corresponding author
1 VisAGeS - Vision, Action et Gestion d'informations en Santé
INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
Abstract : Subthalamic nucleus (STN) deep brain stimulation (DBS) has been demonstrated as an efficient surgical treatment in patients with Parkinson's disease suffering from severe disabilities in their motor symptoms (tremor, akinesia, rigidity) [1]. Sometimes, patients with STN DBS have secondary neuropsychological and/or psychiatric effects because the STN has a small size and a functional subdivision into motor, associative and limbic parts [8]. Therefore, targeting is an important step of the neurosurgical procedure as the DBS could induce undesirable side-effects. To improve targeting, many authors created either anatomical atlases [2,4] or multimodal databases [5-7]. They demonstrated that multimodal databases improved targeting accuracy over anatomical atlases. We presented a validation automatic segmentation of the basal ganglia based on a manual segmentation of these structures completed on a 3T MRI-template. This is the first step to increase accuracy of the targeting of DBS in order to improve the clinical outcome of DBS procedures.
Complete list of metadatas

Cited literature [10 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00632521
Contributor : Florent Lalys <>
Submitted on : Friday, October 14, 2011 - 3:24:09 PM
Last modification on : Monday, March 4, 2019 - 2:07:55 PM
Long-term archiving on : Sunday, January 15, 2012 - 2:23:08 AM

Files

Abstract-HBM.pdf
Files produced by the author(s)

Identifiers

  • HAL Id : inserm-00632521, version 1

Citation

Claire Haegelen, Nicolas Guizard, Pierrick Coupé, Florent Lalys, Pierre Jannin, et al.. Validation of basal ganglia segmentation on a 3T MRI template. Human Brain Mapping, Jun 2011, Quebec City, Canada. ⟨inserm-00632521⟩

Share

Metrics

Record views

1577

Files downloads

535