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Journal articles
Adult male circumcision as an intervention against HIV: An operational study of uptake in a South African community (ANRS 12126).
Abstract : ABSTRACT: BACKGROUND: To evaluate the knowledge, attitudes and beliefs about adult male circumcision (AMC), assess the association of AMC with HIV incidence and prevalence, and estimate AMC uptake in a Southern African community. METHODS: A cross-sectional biomedical survey (ANRS-12126) conducted in 2007-2008 among a random sample of 1198 men aged 15 to 49 from Orange Farm (South Africa). Face-to-face interviews were conducted by structured questionnaire. Recent HIV infections were evaluated using the BED incidence assay. Circumcision status was self-reported and clinically assessed. Adjusted HIV incidence rate ratios (aIRR) and prevalence ratios (aPR) were calculated using Poisson regression. RESULTS: The response rate was 73.9%. Most respondents agreed that circumcised men could become HIV infected and needed to use condoms, although 19.3% (95%CI: 17.1% to 21.6%) asserted that AMC protected fully against HIV. Among self-reported circumcised men, 44.9% (95%CI: 39.6% to 50.3%) had intact foreskins. Men without foreskins had lower HIV incidence and prevalence than men with foreskins (aIRR=0.35; 95%CI: 0.14 to 0.88; aPR=0.45, 95%CI: 0.26 to 0.79). No significant difference was found between self-reported circumcised men with foreskins and other uncircumcised men. Intention to undergo AMC was associated with ethnic group and partner and family support of AMC. Uptake of AMC was 58.8% (95%CI: 55.4% to 62.0%). CONCLUSIONS: AMC uptake in this community is high but communication and counseling should emphasize what clinical AMC is and its effect on HIV acquisition. These findings suggest that AMC roll-out is promising but requires careful implementation strategies to be successful against the African HIV epidemic.
Cited literature [20 references]
https://www.hal.inserm.fr/inserm-00632064
Contributor : Ed. Bmc <>
Submitted on : Thursday, October 13, 2011 - 1:07:02 PM
Last modification on : Wednesday, September 16, 2020 - 5:04:38 PM
Long-term archiving on: : Tuesday, November 13, 2012 - 4:40:53 PM
Contributor : Ed. Bmc <>
Submitted on : Thursday, October 13, 2011 - 1:07:02 PM
Last modification on : Wednesday, September 16, 2020 - 5:04:38 PM
Long-term archiving on: : Tuesday, November 13, 2012 - 4:40:53 PM