Micro computed tomography for vascular exploration.

Abstract : Vascular exploration of small animals requires imaging hardware with a very high spatial resolution, capable of differentiating large as well as small vessels, in both in vivo and ex vivo studies. Micro Computed Tomography (micro-CT) has emerged in recent years as the preferred modality for this purpose, providing high resolution 3D volumetric data suitable for analysis, quantification, validation, and visualization of results. The usefulness of micro-CT, however, can be adversely affected by a range of factors including physical animal preparation, numerical quantification, visualization of results, and quantification software with limited possibilities. Exacerbating these inherent difficulties is the lack of a unified standard for micro-CT imaging. Most micro-CT today is aimed at particular applications and the software tools needed for quantification, developed mainly by imaging hardware manufacturers, lack the level of detail needed to address more specific aims. This review highlights the capabilities of micro-CT for vascular exploration, describes the current state of imaging protocols, and offers guidelines and suggestions aimed at making micro-CT more accurate, replicable, and robust.
Type de document :
Article dans une revue
Journal of Angiogenesis Research, 2010, 2 (1), pp.7. 〈10.1186/2040-2384-2-7〉
Liste complète des métadonnées

Littérature citée [40 références]  Voir  Masquer  Télécharger

Contributeur : Christelle Boullé <>
Soumis le : lundi 12 septembre 2011 - 15:15:31
Dernière modification le : lundi 19 février 2018 - 14:38:03
Document(s) archivé(s) le : mardi 13 novembre 2012 - 10:21:50





Lyubomir Zagorchev, Pierre Oses, Zhen Zhuang, Karen Moodie, Mary Mulligan-Kehoe, et al.. Micro computed tomography for vascular exploration.. Journal of Angiogenesis Research, 2010, 2 (1), pp.7. 〈10.1186/2040-2384-2-7〉. 〈inserm-00622568〉



Consultations de la notice


Téléchargements de fichiers