T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function, The Journal of Experimental Medicine, vol.139, issue.1, pp.63-75, 2000. ,
DOI : 10.1086/314868
Human CD4+ CD25+ Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens, Journal of Virology, vol.78, issue.5, pp.2454-2459, 2004. ,
DOI : 10.1128/JVI.78.5.2454-2459.2004
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC369239
An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection, Hepatology, vol.3, issue.5, pp.1062-1071, 2004. ,
DOI : 10.1002/hep.20454
HIV-specific T Cell Immune Responses In Vitro and Are Associated with Favorable Clinical Markers of Disease Status, The Journal of Experimental Medicine, vol.38, issue.3, pp.331-343, 2004. ,
DOI : 10.1016/S0006-291X(02)02460-9
HIV-specific regulatory T cells are associated with higher CD4 cell counts in primary infection, AIDS, vol.22, issue.18, pp.2451-2460, 2008. ,
DOI : 10.1097/QAD.0b013e328319edc0
URL : https://hal.archives-ouvertes.fr/inserm-00350026
Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients, Blood, vol.104, issue.10, pp.3249-3256, 2004. ,
DOI : 10.1182/blood-2004-01-0365
The inhibitory cytokine IL-35 contributes to regulatory T-cell function, Nature, vol.24, issue.7169, pp.566-569, 2007. ,
DOI : 10.1038/nature06306
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease, Proceedings of the National Academy of Sciences, vol.101, issue.28, pp.10398-10403, 2004. ,
DOI : 10.1073/pnas.0403342101
How regulatory T cells work, Nature Reviews Immunology, vol.178, issue.7, pp.523-532, 2008. ,
DOI : 10.1038/nri2343
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression, Blood, vol.110, issue.4, pp.1225-1232, 2007. ,
DOI : 10.1182/blood-2006-12-064527
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression, The Journal of Experimental Medicine, vol.261, issue.6, pp.1257-1265, 2007. ,
DOI : 10.1074/jbc.275.3.2057
Increased Ectonucleotidase Expression and Activity in Regulatory T Cells of Patients with Head and Neck Cancer, Clinical Cancer Research, vol.15, issue.20, pp.6348-6357, 2009. ,
DOI : 10.1158/1078-0432.CCR-09-1143
CD73 is involved in lymphocyte binding to the endothelium: characterization of lymphocyte-vascular adhesion protein 2 identifies it as CD73, Journal of Experimental Medicine, vol.182, issue.5, pp.1603-1608, 1995. ,
DOI : 10.1084/jem.182.5.1603
Adenosine 5???-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation, Pharmacology & Therapeutics, vol.112, issue.2, pp.358-404, 2006. ,
DOI : 10.1016/j.pharmthera.2005.04.013
The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance, Purinergic Signalling, vol.74, issue.2, pp.409-430, 2006. ,
DOI : 10.1007/s11302-006-9003-5
The critical role of adenosine A2A receptors in downregulation of inflammation and immunity in the pathogenesis of infectious diseases, Microbes and Infection, vol.5, issue.6, pp.515-526, 2003. ,
DOI : 10.1016/S1286-4579(03)00068-6
Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of Tcell activation and expansion, Blood, vol.90, pp.1600-1610, 1997. ,
The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization, J Immunol, vol.153, pp.3574-3583, 1994. ,
New class I and II HLA alleles strongly associated with opposite patterns of progression to AIDS, J Immunol, vol.162, pp.6942-6946, 1999. ,
CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease, Proceedings of the National Academy of Sciences, vol.106, issue.39, pp.16788-16793, 2009. ,
DOI : 10.1073/pnas.0902869106
Genomewide Association Study of a Rapid Progression Cohort Identifies New Susceptibility Alleles for AIDS (ANRS Genomewide Association Study 03), The Journal of Infectious Diseases, vol.200, issue.8, 2009. ,
DOI : 10.1086/605892
Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes, 2009. ,
WGAViewer: Software for genomic annotation of whole genome association studies, Genome Research, vol.18, issue.4, pp.640-643, 2008. ,
DOI : 10.1101/gr.071571.107
A genome-wide association study of global gene expression, Nature Genetics, vol.32, issue.10, pp.1202-1207, 2007. ,
DOI : 10.1038/ng2109
CD39 and control of cellular immune responses, Purinergic Signalling, vol.41, issue.1-2, pp.171-180, 2007. ,
DOI : 10.1007/s11302-006-9050-y
Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression, Journal of Immunological Methods, vol.346, issue.1-2, pp.55-63, 2009. ,
DOI : 10.1016/j.jim.2009.05.004
HIV infection is associated with increased NTPDase activity that correlates with CD39-positive lymphocytes, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1746, issue.2, pp.129-134, 2005. ,
DOI : 10.1016/j.bbamcr.2005.10.009
Comprehensive Analysis of Frequency and Phenotype of T Regulatory Cells in HIV Infection: CD39 Expression of FoxP3+ T Regulatory Cells Correlates with Progressive Disease, Journal of Virology, vol.85, issue.3, pp.1287-1297, 2011. ,
DOI : 10.1128/JVI.01758-10
CD8 T Cells with Suppressive Potential in Colorectal Mucosa Following a Pathogenic Simian Immunodeficiency Virus Infection Correlates with Diminished Antiviral T Cell Response and Viral Control, The Journal of Immunology, vol.184, issue.4, pp.1690-1701, 2010. ,
DOI : 10.4049/jimmunol.0902955
Pathophysiology and Therapeutic Potential of Purinergic Signaling, Pharmacological Reviews, vol.58, issue.1, pp.58-86, 2006. ,
DOI : 10.1124/pr.58.1.5
High adenosine plasma concentration as a prognostic index for outcome in patients with septic shock, Critical Care Medicine, vol.28, issue.9, pp.3198-3202, 2000. ,
DOI : 10.1097/00003246-200009000-00014
The Inflammasome: First Line of the Immune Response to Cell Stress, Cell, vol.126, issue.4, pp.659-662, 2006. ,
DOI : 10.1016/j.cell.2006.08.002
Activation of Th1 and Tc1 cell adenosine A2A receptors directly inhibits IL-2 secretion in vitro and IL-2-driven expansion in vivo, Blood, vol.105, issue.12, pp.4707-4714, 2005. ,
DOI : 10.1182/blood-2004-04-1407
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage, Nature, vol.120, issue.6866, pp.916-920, 2001. ,
DOI : 10.1038/414916a
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments, The Journal of Immunology, vol.183, issue.9, pp.5487-5493, 2009. ,
DOI : 10.4049/jimmunol.0901247
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells, Blood, vol.111, issue.1, pp.251-259, 2008. ,
DOI : 10.1182/blood-2007-03-081646
T Regulatory and Primed Uncommitted CD4 T Cells Express CD73, Which Suppresses Effector CD4 T Cells by Converting 5'-Adenosine Monophosphate to Adenosine, The Journal of Immunology, vol.177, issue.10, pp.6780-6786, 2006. ,
DOI : 10.4049/jimmunol.177.10.6780
High Sensitivity of CD4+CD25+ Regulatory T Cells to Extracellular Metabolites Nicotinamide Adenine Dinucleotide and ATP: A Role for P2X7 Receptors, The Journal of Immunology, vol.175, issue.5, pp.3075-3083, 2005. ,
DOI : 10.4049/jimmunol.175.5.3075
Characterization of adenosine deaminase binding to human CD26 on T cells and its biologic role in immune response, J Immunol, vol.156, pp.1349-1355, 1996. ,
The ???danger??? sensors that STOP the immune response: the A2 adenosine receptors?, Trends in Immunology, vol.26, issue.6, pp.299-304, 2005. ,
DOI : 10.1016/j.it.2005.04.004
Immune Suppression in the Tumor Microenvironment, Journal of Immunotherapy, vol.29, issue.3, pp.233-240, 2006. ,
DOI : 10.1097/01.cji.0000199193.29048.56
Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals, Proceedings of the National Academy of Sciences, vol.104, issue.9, pp.3390-3395, 2007. ,
DOI : 10.1073/pnas.0611423104
Premature Induction of an Immunosuppressive Regulatory T Cell Response during Acute Simian Immunodeficiency Virus Infection, The Journal of Infectious Diseases, vol.193, issue.5, pp.703-712, 2006. ,
DOI : 10.1086/500368
T Cells, The Journal of Experimental Medicine, vol.96, issue.6, pp.701-712, 2004. ,
DOI : 10.1086/338123
T-cell subsets, Blood, vol.113, issue.19, pp.4556-4565, 2009. ,
DOI : 10.1182/blood-2008-04-151407
URL : https://hal.archives-ouvertes.fr/inserm-00365018
Biochemical analysis and epitope mapping of mAb defining CD39 Leucocyte Typing V, pp.383-385, 1995. ,
Dominant Effects of CCR2-CCR5 Haplotypes in HIV-1 Disease Progression, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.37, issue.4, pp.1534-1538, 2004. ,
DOI : 10.1097/01.qai.0000127353.01578.63
An epidemiologic survey from a network of French Health Examination Centres): epidemiologic data on the insulin resistance syndrome], Rev Epidemiol Sante Publique, vol.44, pp.373-375, 1996. ,
Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection, AIDS, vol.23, issue.1, pp.19-28, 2009. ,
DOI : 10.1097/QAD.0b013e32831db247
Multistage Genomewide Association Study Identifies a Locus at 1q41 Associated with Rate of HIV???1 Disease Progression to Clinical AIDS, The Journal of Infectious Diseases, vol.201, issue.4, pp.618-626, 2010. ,
DOI : 10.1086/649842
Principal components analysis corrects for stratification in genome-wide association studies, Nature Genetics, vol.15, issue.8, pp.904-909, 2006. ,
DOI : 10.1038/ng1653
A new multipoint method for genome-wide association studies by imputation of genotypes, Nature Genetics, vol.164, issue.7, pp.906-913, 2007. ,
DOI : 10.1038/nrg1916
The Genetical Interpretation of Statistics of the Third Degree in the Study of Quantitative Inheritance, Genetics, vol.17, pp.107-124, 1932. ,