Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs. - Archive ouverte HAL Access content directly
Journal Articles Autophagy Year : 2011

Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs.

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Abstract

Oxidized LDLs (oxLDLs) induce various cellular dysfunctions potentially implicated in the pathogenesis of atherosclerosis. For instance, toxic concentrations of oxLDLs trigger ER stress, autophagy and apoptosis. High-density lipoproteins (HDLs) counteract several adverse biological effects triggered by oxLDLs. Our recent study reveals that HDLs inhibit the activation of ER stress and of autophagy induced by oxLDLs.
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Dates and versions

inserm-00615490 , version 1 (19-08-2011)

Identifiers

  • HAL Id : inserm-00615490 , version 1
  • PUBMED : 21412049

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Carole Muller, Robert Salvayre, Anne Nègre-Salvayre, Cécile Vindis. Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs.. Autophagy, 2011, 7 (5), pp.541-3. ⟨inserm-00615490⟩
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