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Multimodal imaging reveals the role of γ activity in eating-reflex seizures.

Thomas Blauwblomme 1 Philippe Kahane 2 Lorella Minotti 1 Frédéric Grouiller 3, 4 Alexandre Krainik 5 Laurent Vercueil 1 Stéphan Chabardès 6 Dominique M. Hoffmann 7 Olivier David 8, * 
* Corresponding author
2 INSERM U836, équipe 9, Dynamique des réseaux synchrones épileptiques
GIN - Grenoble Institut des Neurosciences, IDEE
5 INSERM U836, équipe 5, Neuroimagerie fonctionnelle et perfusion cérébrale
GIN - Grenoble Institut des Neurosciences, Service de neuroradiologie [Grenoble]
6 INSERM U836, équipe 11, Fonctions cérébrales et neuromodulation
GIN - Grenoble Institut des Neurosciences, Département de neurochirurgie
8 INSERM U836, équipe 11, Fonctions cérébrales et neuromodulation
GIN - Grenoble Institut des Neurosciences, Service de neuroradiologie [Grenoble]
Abstract : In reflex epilepsies, alteration of γ oscillations may mediate transition between interictal and ictal states. Here, we explored a patient having seizures triggered by syrup intake. From intracranial electroencephalography combined with functional MRI, the overlap of the gustatory cortex and of the preictal and ictal onset zones, as defined by early gamma changes, motivated the successful resective surgery of the middle short gyrus of the right insula. This case provides a rare demonstration from human gamma activity that the route to seizure may be supported by the interplay between physiological and epileptogenic networks.
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https://www.hal.inserm.fr/inserm-00612950
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Submitted on : Monday, August 1, 2011 - 8:05:38 PM
Last modification on : Thursday, May 20, 2021 - 4:50:02 PM
Long-term archiving on: : Wednesday, November 2, 2011 - 2:22:26 AM

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Thomas Blauwblomme, Philippe Kahane, Lorella Minotti, Frédéric Grouiller, Alexandre Krainik, et al.. Multimodal imaging reveals the role of γ activity in eating-reflex seizures.. Journal of Neurology, Neurosurgery and Psychiatry, BMJ Publishing Group, 2011, 82 (10), pp.1171-3. ⟨10.1136/jnnp.2010.212696⟩. ⟨inserm-00612950⟩

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