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In vitro and in vivo intracellular delivery of quantum dots by maurocalcine

Narendra Ram 1 Isabelle Texier-Nogues 2 Karine Pernet-Gallay 3 Cathy Poillot 1 Fabienne Pirollet 1 Michel Ronjat 1 Annie Andrieux 3 Christophe Arnoult 1 Jean Daou 4 Michel de Waard 1, *
* Corresponding author
1 INSERM U836, équipe 3, Canaux calciques, fonctions et pathologies
GIN - Grenoble Institut des Neurosciences
2 DTBS - Département Microtechnologies pour la Biologie et la Santé
3 INSERM U836, équipe 1, Physiopathologie du cytosquelette
GIN - Grenoble Institut des Neurosciences
4 GIN - Grenoble Institut des Neurosciences
Abstract : Maurocalcine is a new member of the increasing family of cell penetrating peptides. We report for the first time that this peptide is able to deliver quantum dots inside a variety of cells, both in vitro and in vivo. In vivo, maurocalcine produces intracellular delivery of the nanoparticles without affecting the relative distribution of quantum dots within organs. The data stress out that maurocalcine can be used for intracellular delivery of functionalised nanoparticles in vivo.
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https://www.hal.inserm.fr/inserm-00608347
Contributor : Marco Canepari <>
Submitted on : Friday, August 12, 2011 - 7:00:18 AM
Last modification on : Thursday, May 20, 2021 - 4:50:02 PM
Long-term archiving on: : Sunday, November 13, 2011 - 2:20:36 AM

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Narendra Ram, Isabelle Texier-Nogues, Karine Pernet-Gallay, Cathy Poillot, Fabienne Pirollet, et al.. In vitro and in vivo intracellular delivery of quantum dots by maurocalcine. International Journal of Biomedical Nanoscience and Nanotechnology, 2011, 2 (1), pp.12-32. ⟨10.1504/IJBNN.2011.038464⟩. ⟨inserm-00608347⟩

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