A. Keefe, S. Pai, and A. Ellington, Aptamers as therapeutics, Nature Reviews Drug Discovery, vol.390, issue.7, pp.537-550, 2010.
DOI : 10.1038/nrd3141

E. Ng, D. Shima, P. Calias, E. Cunningham, . Jr et al., Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease, Nature Reviews Drug Discovery, vol.22, issue.2, pp.123-132, 2006.
DOI : 10.1038/nrd1955

D. Bunka, O. Platonova, and P. Stockley, Development of aptamer therapeutics, Current Opinion in Pharmacology, vol.10, issue.5, pp.557-562, 2010.
DOI : 10.1016/j.coph.2010.06.009

L. Gold, D. Brown, Y. He, T. Shtatland, B. Singer et al., From oligonucleotide shapes to genomic SELEX: Novel biological regulatory loops, Proceedings of the National Academy of Sciences, vol.94, issue.1, pp.59-64, 1997.
DOI : 10.1073/pnas.94.1.59

S. Gopinath, Methods developed for SELEX, Analytical and Bioanalytical Chemistry, vol.139, issue.1, pp.171-182, 2007.
DOI : 10.1007/s00216-006-0826-2

M. Berezovski, M. Musheev, A. Drabovich, J. Jitkova, and S. Krylov, Non-SELEX: selection of aptamers without intermediate amplification of candidate oligonucleotides, Nature Protocols, vol.74, issue.3, pp.1359-1369, 2006.
DOI : 10.1038/nprot.2006.200

S. Javaherian, M. Musheev, M. Kanoatov, M. Berezovski, and S. Krylov, Selection of aptamers for a protein target in cell lysate and their application to protein purification, Nucleic Acids Research, vol.37, issue.8, p.62, 2009.
DOI : 10.1093/nar/gkp176

S. Taouji, S. Dahan, R. Bosse, and E. Chevet, Current Screens Based on the AlphaScreen™ Technology for Deciphering Cell Signalling Pathways, Current Genomics, vol.10, issue.2, pp.93-101, 2009.
DOI : 10.2174/138920209787847041

R. Eglen, T. Reisine, P. Roby, N. Rouleau, C. Illy et al., The Use of AlphaScreen Technology in HTS: Current Status, Current Chemical Genomics, vol.1, pp.2-10, 2008.
DOI : 10.2174/1875397300801010002

M. Bouchecareilh, M. Caruso, P. Roby, S. Parent, N. Rouleau et al., AlphaScreen(R)-Based Characterization of the Bifunctional Kinase/RNase IRE1??: A Novel and Atypical Drug Target, Journal of Biomolecular Screening, vol.15, issue.4, pp.406-417, 2010.
DOI : 10.1177/1087057110363823

M. Arcand, P. Roby, R. Bosse, F. Lipari, J. Padros et al., Single-Well Monitoring of Protein???Protein Interaction and Phosphorylation???Dephosphorylation Events, Biochemistry, vol.49, issue.15, pp.3213-3215, 2010.
DOI : 10.1021/bi100253p

M. Caruso, S. Jenna, S. Beaulne, E. Lee, A. Bergeron et al., Biochemical Clustering of Monomeric GTPases of the Ras Superfamily, Molecular & Cellular Proteomics, vol.4, issue.7, pp.936-944, 2005.
DOI : 10.1074/mcp.M500025-MCP200

N. Mills, A. Shelat, and R. Guy, Assay Optimization and Screening of RNA-Protein Interactions by AlphaScreen, Journal of Biomolecular Screening, vol.12, issue.7, pp.946-955, 2007.
DOI : 10.1177/1087057107306128

F. Ducongé, D. Primo, C. Toulmé, and J. , Is a Closing "GA Pair" a Rule for Stable Loop-Loop RNA Complexes?, Journal of Biological Chemistry, vol.275, issue.28, pp.21287-21294, 2000.
DOI : 10.1074/jbc.M002694200

H. Van-melckebeke, M. Devany, D. Primo, C. Beaurain, F. Toulmé et al., Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex, Proceedings of the National Academy of Sciences, vol.105, issue.27, pp.9210-9215, 2008.
DOI : 10.1073/pnas.0712121105

I. Lebars, P. Legrand, A. Aimé, N. Pinaud, S. Fribourg et al., Exploring TAR-RNA aptamer loop-loop interaction by X-ray crystallography, UV spectroscopy and surface plasmon resonance, Nucleic Acids Research, vol.36, issue.22, pp.7146-7156, 2008.
DOI : 10.1093/nar/gkn831

URL : https://hal.archives-ouvertes.fr/inserm-00347253

S. Bannwarth and A. Gatignol, HIV-1 TAR RNA: The Target of Molecular Interactions Between the Virus and its Host, Current HIV Research, vol.3, issue.1, pp.61-71, 2005.
DOI : 10.2174/1570162052772924

D. Primo, C. Lebars, and I. , Determination of refractive index increment ratios for protein???nucleic acid complexes by surface plasmon resonance, Analytical Biochemistry, vol.368, issue.2, pp.148-155, 2007.
DOI : 10.1016/j.ab.2007.06.016

URL : https://hal.archives-ouvertes.fr/inserm-00173539

M. Watrin, V. Pelchrzim, F. Dausse, E. Schroeder, R. Toulmé et al., In Vitro Selection of RNA Aptamers Derived from a Genomic Human Library against the TAR RNA Element of HIV-1, Biochemistry, vol.48, issue.26, pp.6278-6284, 2009.
DOI : 10.1021/bi802373d

S. Da-rocha-gomes, E. Dausse, and J. Toulmé, Determinants of apical loop???internal loop RNA???RNA interactions involving the HCV IRES, Biochemical and Biophysical Research Communications, vol.322, issue.3, pp.820-826, 2004.
DOI : 10.1016/j.bbrc.2004.07.185

Y. Zeng, Principles of micro-RNA production and maturation, Oncogene, vol.25, issue.46, pp.6156-6162, 2006.
DOI : 10.1038/nature03817

M. Chekulaeva and W. Filipowicz, Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells, Current Opinion in Cell Biology, vol.21, issue.3, pp.452-460, 2009.
DOI : 10.1016/j.ceb.2009.04.009

G. Michlewski, S. Guil, C. Semple, and J. Caceres, Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops, Molecular Cell, vol.32, issue.3, pp.383-393, 2008.
DOI : 10.1016/j.molcel.2008.10.013

C. Lunse, G. Michlewski, C. Hopp, A. Rentmeister, J. Caceres et al., An Aptamer Targeting the Apical-Loop Domain Modulates pri-miRNA Processing, Angewandte Chemie International Edition, vol.47, issue.27, pp.4674-4677, 2010.
DOI : 10.1002/anie.200906919

M. Zuker, Mfold web server for nucleic acid folding and hybridization prediction, Nucleic Acids Research, vol.31, issue.13, pp.3406-3415, 2003.
DOI : 10.1093/nar/gkg595

E. Dausse, C. Cazenave, B. Rayner, and J. Toulmé, In Vitro Selection Procedures for Identifying DNA and RNA Aptamers Targeted to Nucleic Acids and Proteins, Methods Mol Biol, vol.288, pp.391-410, 2005.
DOI : 10.1385/1-59259-823-4:391

D. Myszka, Improving biosensor analysis, Journal of Molecular Recognition, vol.273, issue.5, pp.279-284, 1999.
DOI : 10.1002/(SICI)1099-1352(199909/10)12:5<279::AID-JMR473>3.0.CO;2-3