R. Benjamin, J. Capparella, and A. Brown, Classification of Glioblastoma Multiforme in Adults by Molecular Genetics, The Cancer Journal, vol.9, issue.2, pp.82-90, 2003.
DOI : 10.1097/00130404-200303000-00003

R. Stupp, W. Mason, M. Van-den-bent, M. Weller, B. Fisher et al., Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma, New England Journal of Medicine, vol.352, issue.10, pp.987-996, 2005.
DOI : 10.1056/NEJMoa043330

T. Reya, S. Morrison, M. Clarke, and I. Weissman, Stem cells, cancer, and cancer stem cells, Nature, vol.414, issue.6859, pp.105-111, 2001.
DOI : 10.1038/35102167

A. Vescovi, R. Galli, and B. Reynolds, Brain tumour stem cells, Nature Reviews Cancer, vol.6, issue.6, pp.425-436, 2006.
DOI : 10.1038/nrc1889

C. Stiles and D. Rowitch, Glioma Stem Cells: A Midterm Exam, Neuron, vol.58, issue.6, pp.832-846, 2008.
DOI : 10.1016/j.neuron.2008.05.031

. Tabuse, http://www.molecular-cancer.com/content/10/1/60 tumor-initiating cells causes stop of proliferation and loss of tumorigenicity, Molecular Cancer Stem Cells, vol.10, issue.27, pp.6040-6088, 2009.

N. Thon, K. Damianoff, J. Hegermann, S. Grau, B. Krebs et al., Presence of pluripotent CD133+ cells correlates with malignancy of gliomas, Molecular and Cellular Neuroscience, vol.43, issue.1, pp.51-59, 2010.
DOI : 10.1016/j.mcn.2008.07.022

S. Singh, I. Clarke, M. Terasaki, V. Bonn, C. Hawkins et al., Identification of a cancer stem cell in human brain tumors, Cancer Res, vol.63, pp.5821-5828, 2003.

M. Son, K. Woolard, D. Nam, J. Lee, and H. Fine, SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma, Cell Stem Cell, vol.4, issue.5, pp.440-452, 2009.
DOI : 10.1016/j.stem.2009.03.003

C. Patru, L. Romao, P. Varlet, L. Coulombel, E. Raponi et al., CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors, BMC Cancer, vol.4, issue.5, p.66, 2010.
DOI : 10.1016/j.stem.2009.03.003
URL : https://hal.archives-ouvertes.fr/inserm-00663773

L. Prestegarden and P. Enger, Cancer Stem Cells in the Central Nervous System - A Critical Review, Cancer Research, vol.70, issue.21, pp.8255-8258, 2010.
DOI : 10.1158/0008-5472.CAN-10-1592

S. Carroll, Homeotic genes and the evolution of arthropods and chordates, Nature, vol.376, issue.6540, pp.479-485, 1995.
DOI : 10.1038/376479a0

N. Shah and S. Sukumar, The Hox genes and their roles in oncogenesis, Nature Reviews Cancer, vol.304, issue.2, pp.361-371, 2010.
DOI : 10.1038/nrc2826

B. Barber and M. Rastegar, Epigenetic control of Hox genes during neurogenesis, development, and disease, Annals of Anatomy - Anatomischer Anzeiger, vol.192, issue.5, pp.261-274, 2010.
DOI : 10.1016/j.aanat.2010.07.009

Y. Ohashi, M. Ueda, T. Kawase, Y. Kawakami, and M. Toda, Identification of an epigenetically silenced gene, RFX1, in human glioma cells using restriction landmark genomic scanning, Oncogene, vol.23, issue.47, pp.7772-7779, 2004.
DOI : 10.1038/sj.onc.1208058

C. Fromental-ramain, X. Warot, S. Lakkaraju, B. Favier, H. Haack et al., Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning, pp.461-472, 1996.

B. Morgan and C. Tabin, Hox genes and growth: early and late roles in limb bud morphogenesis, Dev, pp.181-186, 1994.

R. Abdel-fattah, A. Xiao, D. Bomgardner, C. Pease, M. Lopes et al., Differential expression ofHOX genes in neoplastic and non-neoplastic human astrocytes, The Journal of Pathology, vol.2, issue.1, pp.15-24, 2006.
DOI : 10.1002/path.1939

A. Buccoliero, F. Castiglione, D. Degl-'innocenti, F. Ammanati, F. Giordano et al., Hox-D Genes Expression in Pediatric Low-grade Gliomas: Real-time-PCR Study, Cellular and Molecular Neurobiology, vol.25, issue.1, pp.1-6, 2009.
DOI : 10.1007/s10571-008-9282-1

P. Kleihues, D. Louis, B. Scheithauer, L. Rorke, G. Reifenberger et al., The WHO Classification of Tumors of the Nervous System, Journal of Neuropathology & Experimental Neurology, vol.61, issue.3, pp.215-225, 2002.
DOI : 10.1093/jnen/61.3.215

R. Fukaya, S. Ohta, M. Yamaguchi, H. Fujii, Y. Kawakami et al., Isolation of cancer stem-like cells from a side population of a human glioblastoma cell line, SK-MG-1, Cancer Letters, vol.291, issue.2, pp.150-157, 2009.
DOI : 10.1016/j.canlet.2009.10.010

Y. Hattori, S. Ohta, K. Hamada, H. Yamada-okabe, Y. Kanemura et al., Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1, Biochemical and Biophysical Research Communications, vol.364, issue.4, pp.737-742, 2007.
DOI : 10.1016/j.bbrc.2007.10.041

J. Brown and S. Dunmore, Leptin decreases apoptosis and alters BCL-2 : Bax ratio in clonal rodent pancreatic beta-cells, Diabetes/Metabolism Research and Reviews, vol.22, issue.6, pp.497-502, 2007.
DOI : 10.1002/dmrr.726

N. Williams, R. Gaynor, S. Scoggin, U. Verma, T. Gokaslan et al., Identification and validation of genes involved in the pathogenesis of colorectal cancer using cDNA microarrays and RNA interference, Clin Cancer Res, vol.9, pp.931-946, 2003.

R. Roth, P. Hevezi, J. Lee, D. Willhite, S. Lechner et al., Gene expression analyses reveal molecular relationships among 20 regions of the human CNS, Neurogenetics, vol.3, issue.2, pp.67-80, 2006.
DOI : 10.1007/s10048-006-0032-6

M. Kool, J. Koster, J. Bunt, N. Hasselt, A. Lakeman et al., Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features, PLoS ONE, vol.70, issue.8, p.3088, 2008.
DOI : 10.1371/journal.pone.0003088.s010

L. Sun, A. Hui, Q. Su, A. Vortmeyer, Y. Kotliarov et al., Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain, Cancer Cell, vol.9, issue.4, pp.287-300, 2006.
DOI : 10.1016/j.ccr.2006.03.003

M. Nitta, O. Kobayashi, S. Honda, T. Hirota, S. Kuninaka et al., Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents, Oncogene, vol.23, issue.39, pp.6548-6558, 2004.
DOI : 10.1038/sj.onc.1207873

H. Hetschko, V. Voss, S. Horn, V. Seifert, J. Prehn et al., Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma, Journal of Neuro-Oncology, vol.265, issue.3, pp.265-272, 2008.
DOI : 10.1007/s11060-007-9472-6

H. Ikushima, T. Todo, Y. Ino, M. Takahashi, K. Miyazawa et al., Autocrine TGF-?? Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors, Cell Stem Cell, vol.5, issue.5, pp.504-514, 2009.
DOI : 10.1016/j.stem.2009.08.018

Y. Kanemura, H. Mori, S. Kobayashi, O. Islam, E. Kodama et al., Evaluation of in vitro proliferative activity of human fetal neural stem/progenitor cells using indirect measurements of viable cells based on cellular metabolic activity, Journal of Neuroscience Research, vol.7, issue.6, pp.869-879, 2002.
DOI : 10.1002/jnr.10377

S. Ishikawa and K. Ito, Plasticity and regulatory mechanisms of Hox gene expression in mouse neural crest cells, Cell and Tissue Research, vol.453, issue.3, pp.381-391, 2009.
DOI : 10.1007/s00441-009-0827-5

D. Radisky, Defining a role for the homeoprotein Six1 in EMT and mammary tumorigenesis, Journal of Clinical Investigation, vol.119, issue.9, pp.2528-2531, 2009.
DOI : 10.1172/JCI40555

K. Mohankumar, J. Perry, N. Kannan, K. Kohno, P. Gluckman et al., Transcriptional Activation of Signal Transducer and Activator of Transcription (STAT) 3 and STAT5B Partially Mediate Homeobox A1-Stimulated Oncogenic Transformation of the Immortalized Human Mammary Epithelial Cell, Endocrinology, vol.149, issue.5, pp.2219-2229, 2008.
DOI : 10.1210/en.2007-1320

A. Bendall, J. Ding, G. Hu, and M. Shen, Abate-Shen C: Msx1 antagonizes the myogenic activity of Pax3 in migrating limb muscle precursors, Development, vol.126, pp.4965-4976, 1999.

N. Gao, P. White, and K. Kaestner, Establishment of Intestinal Identity and Epithelial-Mesenchymal Signaling by Cdx2, Developmental Cell, vol.16, issue.4, pp.588-599, 2009.
DOI : 10.1016/j.devcel.2009.02.010

J. Rinn, M. Kertesz, J. Wang, S. Squazzo, X. Xu et al., Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs, Cell, vol.129, issue.7, pp.1311-1323, 2007.
DOI : 10.1016/j.cell.2007.05.022

C. Woo, P. Kharchenko, L. Daheron, P. Park, and R. Kingston, A Region of the Human HOXD Cluster that Confers Polycomb-Group Responsiveness, Cell, vol.140, issue.1, pp.99-110, 2010.
DOI : 10.1016/j.cell.2009.12.022

D. Flagiello, M. Poupon, C. Cillo, B. Dutrillaux, and B. Malfoy, gene cluster in small cell lung cancers, FEBS Letters, vol.88, issue.1-2, pp.103-107, 1996.
DOI : 10.1016/0014-5793(96)00017-8

X. Wu, T. Rauch, X. Zhong, W. Bennett, F. Latif et al., CpG Island Hypermethylation in Human Astrocytomas, Cancer Research, vol.70, issue.7, pp.2718-2727, 2010.
DOI : 10.1158/0008-5472.CAN-09-3631

N. Nguyen, T. Hirose, M. Nakazawa, T. Kobata, H. Nakamura et al., Expression of HOXD9 in fibroblast-like synoviocytes from rheumatoid arthritis patients, Int J Mol Med, vol.10, pp.41-48, 2002.

D. Liu, Z. Gu, X. Cao, H. Liu, and J. Li, Immunocytochemical detection of HoxD9 and Pbx1 homeodomain protein expression in Chinese esophageal squamous cell carcinomas, World Journal of Gastroenterology, vol.11, issue.10, pp.1562-1566, 2005.
DOI : 10.3748/wjg.v11.i10.1562

K. Willert, J. Brown, E. Danenberg, A. Duncan, I. Weissman et al., Wnt proteins are lipid-modified and can act as stem cell growth factors, Nature, vol.367, issue.6938, pp.448-452, 2003.
DOI : 10.1084/jem.192.12.1707

M. Garcia-castro, C. Marcelle, and M. Bronner-fraser, Ectodermal Wnt function as a neural crest inducer, Science, vol.297, pp.848-851, 2002.
URL : https://hal.archives-ouvertes.fr/hal-00311348

M. Gouti and A. Gavalas, Hoxb1 Controls Cell Fate Specification and Proliferative Capacity of Neural Stem and Progenitor Cells, Stem Cells, vol.26, issue.8, pp.1985-1997, 2008.
DOI : 10.1634/stemcells.2008-0182

S. Lu, Q. Feng, Y. Ivanova, C. Luo, T. Li et al., Recombinant HoxB4 Fusion Proteins Enhance Hematopoietic Differentiation of Human Embryonic Stem Cells, Stem Cells and Development, vol.16, issue.4, pp.547-559, 2007.
DOI : 10.1089/scd.2007.0002

B. Zhou, H. Zhang, M. Damelin, K. Geles, J. Grindley et al., Tumour-initiating cells: challenges and opportunities for anticancer drug discovery, Nature Reviews Drug Discovery, vol.66, issue.10, pp.806-823, 2009.
DOI : 10.1038/nrd2137

B. Costa, J. Smith, Y. Chen, J. Chen, H. Phillips et al., Reversing HOXA9 Oncogene Activation by PI3K Inhibition: Epigenetic Mechanism and Prognostic Significance in Human Glioblastoma, Cancer Research, vol.70, issue.2, pp.453-462, 2010.
DOI : 10.1158/0008-5472.CAN-09-2189

A. Murat, E. Migliavacca, T. Gorlia, W. Lambiv, T. Shay et al., Stem Cell???Related ???Self-Renewal??? Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma, Journal of Clinical Oncology, vol.26, issue.18, pp.3015-3024, 2008.
DOI : 10.1200/JCO.2007.15.7164

. Tabuse, Molecular Cancer http://www.molecular-cancer.com/content, p.6060, 2011.