Skip to Main content Skip to Navigation
Conference papers

Improving arterial spin labeling by temporal filtering

Jan Petr 1, * Jean-Christophe Ferré 1, 2 Jean-yves Gauvrit 1, 2 Christian Barillot 1 
* Corresponding author
1 VisAGeS - Vision, Action et Gestion d'informations en Santé
INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
Abstract : Arterial spin labeling (ASL) is an MRI method for imaging brain perfusion by magnetically labeling blood in brain feeding arteries. The perfusion is obtained from the difference between images with and without prior labeling. Image noise is one of the main problems of ASL as the difference is around 0.5-2% of the image magnitude. Usually, 20-40 pairs of images need to be acquired and averaged to reach a satisfactory quality. The images are acquired shortly after the labeling to allow the labeled blood to reach the imaged slice. A sequence of images with multiple delays is more suitable for quantification of the cerebral blood flow as it gives more information about the blood arrival and relaxation. Although the quantification methods are sensitive to noise, no filtering or only Gaussian filtering is used to denoise the data in the temporal domain prior to quantification. In this article, we propose an efficient way to use the redundancy of information in the time sequence of each pixel to suppress noise. For this purpose, the vectorial NL-means method is adapted to work in the temporal domain. The proposed method is tested on simulated and real 3T MRI data. We demonstrate a clear improvement of the image quality as well as a better performance compared to Gaussian and normal spatial NL-means filtering.
Complete list of metadata
Contributor : Jan Petr Connect in order to contact the contributor
Submitted on : Thursday, June 16, 2011 - 7:07:57 PM
Last modification on : Monday, June 27, 2022 - 3:02:14 AM
Long-term archiving on: : Friday, November 9, 2012 - 3:15:20 PM


Files produced by the author(s)



Jan Petr, Jean-Christophe Ferré, Jean-yves Gauvrit, Christian Barillot. Improving arterial spin labeling by temporal filtering. SPIE Medical Imaging 2010: Image Processing, Feb 2010, San Diego, United States. pp.n.a, ⟨10.1117/12.843960⟩. ⟨inserm-00601146⟩



Record views


Files downloads