The plant Rad50-Mre11 protein complex.

Abstract : The Rad50-Mre11-Xrs2/Nbs1 protein complex plays critical roles in cellular processes involving DNA ends. This complex is implicated in DNA recombination and replication, meiosis, telomere maintenance and cellular DNA damage responses. The Rad50 and Mre11 proteins are essential for viability in animals, although not in yeast. We have prepared antibodies to the Rad50 protein of the model plant Arabidopsis thaliana which recognize a 175 kDa protein in wild-type Arabidopsis protein extracts. Furthermore, we report here demonstration of the existence of the Rad50-Mre11 complex by co-immunoprecipitation of the Rad50 and Mre11 proteins from the plant cell extracts.
Type de document :
Article dans une revue
FEBS Letters, Wiley, 2002, 516 (1-3), pp.164-6
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Contributeur : Charles White <>
Soumis le : mercredi 25 mai 2011 - 16:17:24
Dernière modification le : mercredi 25 juillet 2018 - 10:52:02


  • HAL Id : inserm-00595830, version 1
  • PUBMED : 11959125



S. Daoudal-Cotterell, Maria Eugenia Gallego, Charles White. The plant Rad50-Mre11 protein complex.. FEBS Letters, Wiley, 2002, 516 (1-3), pp.164-6. 〈inserm-00595830〉



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