Skip to Main content Skip to Navigation
Journal articles

Comparison of patient-ventilator interfaces based on their computerized effective dead space.: Interface dead space in non-invasive ventilation

Redouane Fodil 1 François Lellouche 2 Jordi Mancebo 3 Gabriela Sbirlea-Apiou 4 Daniel Isabey 4 Laurent Brochard 5 Bruno Louis 4, *
* Corresponding author
1 INSERM U955, équipe 13
IMRB - Institut Mondor de Recherche Biomédicale
4 INSERM U955, équipe 13
IMRB - Institut Mondor de Recherche Biomédicale, BCR - Biomécanique cellulaire et respiratoire
5 INSERM U955, équipe 13
Service de réanimation médicale, IMRB - Institut Mondor de Recherche Biomédicale, BCR - Biomécanique cellulaire et respiratoire
Abstract : PURPOSE: Non-invasive ventilation is largely used to treat acute and chronic respiratory failure. This ventilation encounters a non-negligible rate of failure related to the used interface/mask, but the reasons for this failure remain unclear. In order to shed light on this issue and to better understand the effects of the geometrical design of interfaces, we aimed to quantify flow, pressure and gas composition in terms of CO(2) and O(2) at the passage through different types of interface (oronasal mask, integral mask and helmet). In particular, we postulated that due to specific gas flow passing throughout the interface, the effective dead space added by the interface is not always related to the whole gas volume included in the interface. METHODS: Numerical simulations, using computational fluid dynamics, were used to describe pressure, flow and gas composition during ventilation with the different interfaces. RESULTS: Between the different interfaces the effective dead spaces differed only modestly (110-370 ml), whereas their internal volumes were markedly different (110-10,000 ml). Effective dead space was limited to half the tidal volume for the most voluminous interface, whereas it was close to the interface gas volume for the less voluminous interfaces. Pressure variations induced by the flow ventilation throughout the interface were negligible. CONCLUSIONS: Effective dead space is not related to the internal gas volume included in the interface, suggesting that this internal volume should not be considered as a limiting factor for their efficacy during non-invasive ventilation. Patient's comfort and synchrony have also to be taken into account.
Document type :
Journal articles
Complete list of metadatas

Cited literature [30 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00595406
Contributor : Georges Guellaen <>
Submitted on : Thursday, November 24, 2011 - 7:00:03 AM
Last modification on : Wednesday, August 19, 2020 - 11:18:04 AM
Long-term archiving on: : Saturday, February 25, 2012 - 2:20:15 AM

Files

MaskCFDRforHAL.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Redouane Fodil, François Lellouche, Jordi Mancebo, Gabriela Sbirlea-Apiou, Daniel Isabey, et al.. Comparison of patient-ventilator interfaces based on their computerized effective dead space.: Interface dead space in non-invasive ventilation. Intensive Care Med, 2011, 37 (2), pp.257-62. ⟨10.1007/s00134-010-2066-3⟩. ⟨inserm-00595406⟩

Share

Metrics

Record views

473

Files downloads

934