Intrahippocampal infusion of botulinum neurotoxin E (BoNT/E) reduces spontaneous recurrent seizures in a mouse model of mesial temporal lobe epilepsy, Epilepsia, vol.46, issue.4, pp.963-966, 2009. ,
DOI : 10.1111/j.1528-1167.2008.01983.x
BDNF and epilepsy: too much of a good thing? Trends Neurosci, pp.47-53, 2001. ,
Selective inhibition of kindling development by intraventricular administration of TrkB receptor body, J. Neurosci, vol.19, pp.1424-1436, 1999. ,
Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy, Neuroscience, vol.89, issue.3, pp.717-729, 1999. ,
DOI : 10.1016/S0306-4522(98)00401-1
Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures, Journal of Neuroinflammation, vol.7, issue.1, p.81, 2010. ,
DOI : 10.1186/1742-2094-7-81
The mesio-temporal lobe epilepsy syndrome Epileptic syndromes in infancy, childhood and adolescence, pp.513-530, 2002. ,
Early childhood prolonged febrile convulsions, atrophy and sclerosis of mesial structures, and temporal lobe epilepsy: An MRI volumetric study, Neurology, vol.43, issue.6, pp.1083-1087, 1993. ,
DOI : 10.1212/WNL.43.6.1083
Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex, Neuroscience, vol.93, issue.4, pp.1491-1506, 1999. ,
DOI : 10.1016/S0306-4522(99)00296-1
Increased expression of brainderived neurotrophic factor induces formation of basal dendrites and axonal branching in dentate granule cells in hippocampal explant cultures, J. Neurosci, vol.22, pp.9754-9763, 2002. ,
Impaired hippocampal rhythmogenesis in a mouse model of mesial temporal lobe epilepsy, Proc. Natl Acad. Sci. USA, pp.17530-17535, 2007. ,
DOI : 10.1073/pnas.0708301104
Naturally occurring truncated trkB receptors have dominant inhibitory effects on brainderived neurotrophic factor signaling, J. Neurosci, vol.16, pp.3123-3129, 1996. ,
Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizures, Neuroscience, vol.83, issue.2, pp.351-362, 1998. ,
DOI : 10.1016/S0306-4522(97)00387-4
Mesial temporal lobe epilepsy: what have we learned?, Neuroscientist, vol.7, pp.340-352, 2001. ,
Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family, Neuron, vol.5, issue.4, pp.511-526, 1990. ,
DOI : 10.1016/0896-6273(90)90090-3
Long-term alterations in growth factor mRNA expression following seizures, NeuroReport, vol.8, issue.6, pp.1445-1449, 1997. ,
DOI : 10.1097/00001756-199704140-00024
Truncated trkB.T1 Is Dominant Negative Inhibitor of trkB.TK+-Mediated Cell Survival, Biochemical and Biophysical Research Communications, vol.280, issue.5, pp.1352-1358, 2001. ,
DOI : 10.1006/bbrc.2001.4296
Entorhinal cortex lesion does not alter reelin messenger RNA expression in the dentate gyrus of young and adult rats, Neuroscience, vol.97, issue.1, pp.25-31, 2000. ,
DOI : 10.1016/S0306-4522(00)00007-5
Role for reelin in the development of granule cell dispersion in temporal lobe epilepsy, J. Neurosci, vol.22, pp.5797-5802, 2002. ,
Conditional Deletion of TrkB but Not BDNF Prevents Epileptogenesis in the Kindling Model, Neuron, vol.43, issue.1, pp.31-42, 2004. ,
DOI : 10.1016/j.neuron.2004.06.019
Reelin Deficiency and Displacement of Mature Neurons, But Not Neurogenesis, Underlie the Formation of Granule Cell Dispersion in the Epileptic Hippocampus, Journal of Neuroscience, vol.26, issue.17, pp.4701-4713, 2006. ,
DOI : 10.1523/JNEUROSCI.5516-05.2006
URL : https://hal.archives-ouvertes.fr/inserm-00388242
Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain, EMBO J, vol.9, pp.2459-2464, 1990. ,
Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy, Brain Research, vol.535, issue.2, pp.195-204, 1990. ,
DOI : 10.1016/0006-8993(90)91601-C
: Roles in Neuronal Development and Function, Annual Review of Neuroscience, vol.24, issue.1, pp.677-736, 2001. ,
DOI : 10.1146/annurev.neuro.24.1.677
The role of cytokines and growth factors in seizures and their sequelae, Progress in Neurobiology, vol.63, issue.2, pp.125-149, 2001. ,
DOI : 10.1016/S0301-0082(00)00022-8
Neurotrophin-evoked rapid excitation through TrkB receptors, Nature, vol.401, pp.918-921, 1999. ,
DOI : 10.1016/s0079-6123(00)28021-7
Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus, Science, vol.267, issue.5204, pp.1658-1662, 1995. ,
DOI : 10.1126/science.7886457
Neurotrophin signal transduction in the nervous system, Current Opinion in Neurobiology, vol.10, issue.3, pp.381-391, 2000. ,
DOI : 10.1016/S0959-4388(00)00092-1
The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain, Cell, vol.61, issue.4, pp.647-656, 1990. ,
DOI : 10.1016/0092-8674(90)90476-U
Trks: Signal transduction and intracellular pathways, Microscopy Research and Technique, vol.87, issue.4-5, pp.210-216, 1999. ,
DOI : 10.1002/(SICI)1097-0029(19990515/01)45:4/5<210::AID-JEMT4>3.0.CO;2-F
Suppressed Epileptogenesis in BDNF Mutant Mice, Experimental Neurology, vol.133, issue.2, pp.215-224, 1995. ,
DOI : 10.1006/exnr.1995.1024
Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB???PLC?? pathway, reduced anxiety, and facilitated learning, Molecular and Cellular Neuroscience, vol.26, issue.1, pp.166-181, 2004. ,
DOI : 10.1016/j.mcn.2004.01.006
Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures, European Journal of Neuroscience, vol.45, issue.Suppl. 6, pp.1916-1927, 2005. ,
DOI : 10.1111/j.1460-9568.2005.04386.x
Exacerbated status epilepticus and acute cell loss, but no changes in epileptogenesis, in mice with increased brain-derived neurotrophic factor signaling, Neuroscience, vol.122, issue.4, pp.1081-1092, 2003. ,
DOI : 10.1016/j.neuroscience.2003.08.037
Decreased BDNF signalling in transgenic mice reduces epileptogenesis, European Journal of Neuroscience, vol.31, issue.4, pp.721-734, 2002. ,
DOI : 10.1016/s0306-4522(99)00251-1
Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat, NeuroReport, vol.6, issue.14, pp.1937-1941, 1995. ,
DOI : 10.1097/00001756-199510020-00027
Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment, Molecular Brain Research, vol.47, issue.1-2, pp.183-194, 1997. ,
DOI : 10.1016/S0169-328X(97)00043-0
Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors., Proc. Natl Acad. Sci. USA 92, pp.8074-8077, 1995. ,
DOI : 10.1073/pnas.92.17.8074
The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy, Brain, vol.118, issue.1, pp.105-118, 1995. ,
DOI : 10.1093/brain/118.1.105
The pathogenic and progressive features of chronic human hippocampal epilepsy, Epilepsy Research, vol.26, issue.1, pp.151-161, 1996. ,
DOI : 10.1016/S0920-1211(96)00052-6
Short-term changes in bilateral hippocampal coherence precede epileptiform events, NeuroImage, vol.38, issue.1, pp.138-149, 2007. ,
DOI : 10.1016/j.neuroimage.2007.07.016
URL : https://hal.archives-ouvertes.fr/inserm-00385565
Acute intrahippocampal infusion of BDNF induces lasting potentiation of synaptic transmission in the rat dentate gyrus, J. Neurophysiol, vol.79, pp.496-499, 1998. ,
trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors., Molecular and Cellular Biology, vol.11, issue.1, pp.143-153, 1991. ,
DOI : 10.1128/MCB.11.1.143
Granule cell dispersion develops without neurogenesis and does not fully depend on astroglial cell generation in a mouse model of temporal lobe epilepsy, Epilepsia, vol.64, issue.18, pp.1711-1722, 2008. ,
DOI : 10.1111/j.1528-1167.2008.01595.x
URL : https://hal.archives-ouvertes.fr/inserm-00410610
Brain-derived neurotrophic factor infusion delays amygdala and perforant path kindling without affecting paired-pulse measures of neuronal inhibition in adult rats, Neuroscience, vol.92, issue.4, pp.1367-1375, 1999. ,
DOI : 10.1016/S0306-4522(99)00048-2
Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model, Proc. Natl Acad. Sci. USA, pp.7191-7196, 2009. ,
DOI : 10.1073/pnas.0810710106
Trk receptors: mediators of neurotrophin action, Current Opinion in Neurobiology, vol.11, issue.3, pp.272-280, 2001. ,
DOI : 10.1016/S0959-4388(00)00208-7
The mouse Brain in Stereotaxic Coordinates, 2001. ,
Brain-derived neurotrophic factor delays hippocampal kindling in the rat, Neuroscience, vol.100, issue.4, pp.777-788, 2000. ,
DOI : 10.1016/S0306-4522(00)00351-1
Evolution of hippocampal epileptic activity during the development of hippocampal sclerosis in a mouse model of temporal lobe epilepsy, Neuroscience, vol.112, issue.1, pp.101-111, 2002. ,
DOI : 10.1016/S0306-4522(02)00064-7
Limbic seizures induce a differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3, in the rat hippocampus, Molecular Brain Research, vol.13, issue.1-2, pp.27-33, 1992. ,
DOI : 10.1016/0169-328X(92)90041-9
Endogenous BDNF Protein Is Increased in Adult Rat Hippocampus after a Kainic Acid Induced Excitotoxic Insult but Exogenous BDNF Is Not Neuroprotective, Experimental Neurology, vol.149, issue.2, pp.398-410, 1998. ,
DOI : 10.1006/exnr.1997.6737
trkB-receptor activation contributes to the kainate-induced increase in BDNF mRNA synthesis, Cellular and Molecular Neurobiology, vol.21, issue.4, pp.429-435, 2001. ,
DOI : 10.1023/A:1012775808253
Transgenic Mice Overexpressing Truncated trkB Neurotrophin Receptors in Neurons Show Increased Susceptibility to Cortical Injury after Focal Cerebral Ischemia, Molecular and Cellular Neuroscience, vol.16, issue.2, pp.87-96, 2000. ,
DOI : 10.1006/mcne.2000.0863
Hyperexcitability in combined entorhinal/hippocampal slices of adult rat after exposure to brain-derived neurotrophic factor, J. Neurophysiol, vol.78, pp.1082-1095, 1997. ,
Spontaneous Limbic Seizures after Intrahippocampal Infusion of Brain-Derived Neurotrophic Factor, Experimental Neurology, vol.174, issue.2, pp.201-214, 2002. ,
DOI : 10.1006/exnr.2002.7869
Angels and demons: neurotrophic factors and epilepsy, Trends in Pharmacological Sciences, vol.27, issue.12, pp.631-638, 2006. ,
DOI : 10.1016/j.tips.2006.10.002
Morphogenetic effect of kainate on adult hippocampal neurons associated with a prolonged expression of brain-derived neurotrophic factor, Neuroscience, vol.64, issue.3, pp.665-674, 1995. ,
DOI : 10.1016/0306-4522(94)00463-F
Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus, J. Neurosci, vol.17, pp.2959-2966, 1997. ,
BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus, Neuroscience, vol.114, issue.3, pp.795-805, 2002. ,
DOI : 10.1016/S0306-4522(02)00301-9
Regulation of brain-derived neurotrophic factor (BDNF) expression and release from hippocampal neurons is mediated by non- NMDA type glutamate receptors, J. Neurosci, vol.14, pp.1688-1700, 1994. ,