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Journal articles
Trimmed-likelihood estimation for focal lesions and tissue segmentation in multisequence MRI for multiple sclerosis.
Abstract : We present a new automatic method for segmentation of multiple sclerosis (MS) lesions in magnetic resonance images. The method performs tissue classification using a model of intensities of the normal appearing brain tissues. In order to estimate the model, a trimmed likelihood estimator is initialized with a hierarchical random approach in order to be robust to MS lesions and other outliers present in real images. The algorithm is first evaluated with simulated images to assess the importance of the robust estimator in presence of outliers. The method is then validated using clinical data in which MS lesions were delineated manually by several experts. Our method obtains an average Dice similarity coefficient (DSC) of 0.65, which is close to the average DSC obtained by raters (0.66).
Cited literature [50 references]
https://www.hal.inserm.fr/inserm-00590724
Contributor : Sylvain Prima Connect in order to contact the contributor
Submitted on : Wednesday, May 4, 2011 - 7:01:00 PM
Last modification on : Thursday, January 20, 2022 - 4:20:32 PM
Long-term archiving on: : Friday, August 5, 2011 - 2:42:40 AM
Contributor : Sylvain Prima Connect in order to contact the contributor
Submitted on : Wednesday, May 4, 2011 - 7:01:00 PM
Last modification on : Thursday, January 20, 2022 - 4:20:32 PM
Long-term archiving on: : Friday, August 5, 2011 - 2:42:40 AM
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