A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers", Journal of Translational Medicine, vol.6, issue.1, 2008. ,
DOI : 10.1186/1479-5876-6-81
chaussabel/tracking-scientific-con tent-in-knol, Tracking Scientific Content in Knol. Knol, 2009. ,
Development and Evaluation of Therapeutically Relevant Predictive Classifiers Using Gene Expression Profiling, JNCI Journal of the National Cancer Institute, vol.98, issue.17, pp.1169-1171, 2006. ,
DOI : 10.1093/jnci/djj364
Validation of pharmacogenomic biomarker classifiers for treatment selection, Cancer Biomarkers, vol.2, issue.3-4, pp.89-96, 2006. ,
DOI : 10.3233/CBM-2006-23-402
Development and validation of biomarker classifiers for treatment selection, Journal of Statistical Planning and Inference, vol.138, issue.2, pp.308-320, 2008. ,
DOI : 10.1016/j.jspi.2007.06.010
Lost in translation: Problems and pitfalls in translating laboratory observations to clinical utility, European Journal of Cancer, vol.44, issue.18, pp.2707-2713, 2008. ,
DOI : 10.1016/j.ejca.2008.09.009
FDA: CBER/Guidances/Guidlines/Points to consider, 2009. ,
Therapies in development for castrate-resistant prostate cancer, Expert Review of Anticancer Therapy, vol.8, issue.2, pp.259-268, 2008. ,
DOI : 10.1586/14737140.8.2.259
Biological Variation: from Principles to Practice, 2001. ,
Reference change values: the way forward in monitoring, Annals of Clinical Biochemistry, vol.46, issue.3, pp.264-265, 2009. ,
DOI : 10.1258/acb.2009.009006
Definition of an Immunologic Response Using the Major Histocompatibility Complex Tetramer and Enzyme-Linked Immunospot Assays, Clinical Cancer Research, vol.12, issue.1, pp.107-116, 2006. ,
DOI : 10.1158/1078-0432.CCR-05-0136
Detailed analysis of immunologic effects of the cytotoxic T lymphocyte-associated antigen 4-blocking monoclonal antibody tremelimumab in peripheral blood of patients with melanoma, Journal of Translational Medicine, vol.6, issue.1, p.22, 2008. ,
DOI : 10.1186/1479-5876-6-22
A Prescription for Human Immunology, Immunity, vol.29, issue.6, pp.835-838, 2008. ,
DOI : 10.1016/j.immuni.2008.12.003
Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells, Cytotherapy, vol.11, issue.3, pp.341-355, 2009. ,
DOI : 10.1080/14653240902807034
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736058
CTLA4 blockade increases Th17 cells in patients with metastatic melanoma, Journal of Translational Medicine, vol.7, issue.1, p.35, 2009. ,
DOI : 10.1186/1479-5876-7-35
Quiescent phenotype of tumor-specific CD8+ T cells following immunization, Blood, vol.104, issue.7, pp.1970-1978, 2004. ,
DOI : 10.1182/blood-2004-02-0525
Cells in HIV Infection, AIDS Research and Human Retroviruses, vol.24, issue.1, pp.62-71, 2008. ,
DOI : 10.1089/aid.2007.0125
Functional Heterogeneity of Vaccine-Induced CD8+ T Cells, The Journal of Immunology, vol.168, issue.11, pp.5933-5942, 2002. ,
DOI : 10.4049/jimmunol.168.11.5933
The Granzyme B ELISPOT assay: an alternative to the 51Cr-release assay for monitoring cell-mediated cytotoxicity, Journal of Translational Medicine, vol.1, issue.1, p.14, 2003. ,
DOI : 10.1186/1479-5876-1-14
Application of the Granzyme B ELISPOT Assay for Monitoring Cancer Vaccine Trials, Journal of Immunotherapy, vol.29, issue.3, pp.328-335, 2006. ,
DOI : 10.1097/01.cji.0000203079.35612.c8
New Approaches for Monitoring CTL Activity in Clinical Trials, Adv Exp Med Biol, vol.601, pp.273-284, 2007. ,
DOI : 10.1007/978-0-387-72005-0_29
Application of a Flow Cytometric Cytotoxicity Assay for Monitoring Cancer Vaccine Trials, Journal of Immunotherapy, vol.32, issue.2, pp.186-194, 2009. ,
DOI : 10.1097/CJI.0b013e318197b1b2
Molecular and Functional Profiling of Memory CD8 T Cell Differentiation, Cell, vol.111, issue.6, pp.837-851, 2002. ,
DOI : 10.1016/S0092-8674(02)01139-X
Granzyme B production distinguishes recently activated CD8+ memory cells from resting memory cells, Cellular Immunology, vol.247, issue.1, pp.36-48, 2007. ,
DOI : 10.1016/j.cellimm.2007.07.004
Increased per cell IFN-gamma productivity indicates recent in vivo activation of T cells, Cell Immunol, 2009. ,
A Genomic- and Proteomic-Based Hypothesis on the Eclectic Effects of Systemic Interleukin-2 Administration in the Context of Melanoma-Specific Immunization, Cells Tissues Organs, vol.177, issue.3, pp.124-131, 2003. ,
DOI : 10.1159/000079986
Gene profiling of immune responses against tumors, Current Opinion in Immunology, vol.17, issue.4, pp.423-427, 2005. ,
DOI : 10.1016/j.coi.2005.05.007
Autologous Tumor Rejection in Humans: Trimming the Myths, Immunological Investigations, vol.1, issue.3, pp.437-458, 2006. ,
DOI : 10.4049/jimmunol.168.9.4272
Quantitative imaging of the T cell antitumor response by positron-emission tomography, Proceedings of the National Academy of Sciences, vol.100, issue.3, pp.1232-1237, 2003. ,
DOI : 10.1073/pnas.0337418100
Arming antibodies: prospects and challenges for immunoconjugates, Nature Biotechnology, vol.90, issue.9 ,
DOI : 10.1021/bc050039z
Molecular imaging of lymphoid organs and immune activation by positron emission tomography with a new [18F]-labeled 2???-deoxycytidine analog, Nature Medicine, vol.2, issue.7, pp.783-788, 2008. ,
DOI : 10.1038/nm1724
PET Imaging of Cancer Immunotherapy, Journal of Nuclear Medicine, vol.49, issue.6, pp.865-868, 2008. ,
DOI : 10.2967/jnumed.108.051342
Mechanisms of type-I- and type-II-interferon-mediated signalling, Nature Reviews Immunology, vol.132, issue.5, pp.375-386, 2005. ,
DOI : 10.1001/jama.290.24.3222
Role of the Akt pathway in mRNA translation of interferon-stimulated genes, Proceedings of the National Academy of Sciences, vol.105, issue.12, pp.4808-4813, 2008. ,
DOI : 10.1073/pnas.0710907105
Inteferons pen the JAK???STAT pathway, Seminars in Cell & Developmental Biology, vol.19, issue.4, pp.311-318, 2008. ,
DOI : 10.1016/j.semcdb.2008.08.010
Early detection: Proteomic applications for the early detection of cancer, Nature Reviews Cancer, vol.3, issue.4, pp.267-275, 2003. ,
DOI : 10.1038/nrc1043
Proteomic Approaches to the Diagnosis, Treatment, and Monitoring of Cancer, Adv Exp Med Biol, vol.532, pp.59-68, 2003. ,
DOI : 10.1007/978-1-4615-0081-0_7
Multiplexed Cell Signaling Analysis of Human Breast Cancer Applications for Personalized Therapy, Journal of Proteome Research, vol.7, issue.4, pp.1508-1517, 2008. ,
DOI : 10.1021/pr7008127
Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ., Proceedings of the National Academy of Sciences, vol.85, issue.8, pp.2603-2607, 1998. ,
DOI : 10.1073/pnas.85.8.2603
Chemical labeling strategies for cell biology, Nature Methods, vol.16, issue.8, pp.591-596, 2006. ,
DOI : 10.1038/nmeth906
A Portrait of Tissue Phosphoprotein Stability in the Clinical Tissue Procurement Process, Molecular & Cellular Proteomics, vol.7, issue.10, pp.1998-2018, 2008. ,
DOI : 10.1074/mcp.M700596-MCP200
Changes in Differential Gene Expression because of Warm Ischemia Time of Radical Prostatectomy Specimens, The American Journal of Pathology, vol.161, issue.5, pp.1743-1748, 2002. ,
DOI : 10.1016/S0002-9440(10)64451-3
Core-Shell Hydrogel Particles Harvest, Concentrate and Preserve Labile Low Abundance Biomarkers, PLoS ONE, vol.177, issue.3, p.4763, 2009. ,
DOI : 10.1371/journal.pone.0004763.s001
URL : http://doi.org/10.1371/journal.pone.0004763
Forecasting the cytokine storm following systemic interleukin-2 administration, Journal of Translational Medicine, vol.2, issue.1, p.17, 2004. ,
DOI : 10.1186/1479-5876-2-17
Inflammatory protein profile during systemic high dose interleukin-2 administration, PROTEOMICS, vol.24, issue.2, pp.709-720, 2006. ,
DOI : 10.1002/pmic.200500004
Cell-Level Pharmacokinetic Model of Granulocyte Colony-Stimulating Factor: Implications for Ligand Lifetime and Potency in Vivo, Molecular Pharmacology, vol.63, issue.1, pp.147-158, 2003. ,
DOI : 10.1124/mol.63.1.147
Stimulus Design for Model Selection and Validation in Cell Signaling, PLoS Computational Biology, vol.21, issue.2, p.30, 2008. ,
DOI : 10.1371/journal.pcbi.0040030.sg003
A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus, Immunity, vol.29, issue.1, pp.150-164, 2008. ,
DOI : 10.1016/j.immuni.2008.05.012
Bottom Up: A Modular View of Immunology, Immunity, vol.29, issue.1, pp.9-11, 2008. ,
DOI : 10.1016/j.immuni.2008.07.002
Polymorphism in clinical immunology. From HLA typing to immunogenetic profiling, Journal of Translational Medicine, vol.1, issue.1, p.8, 2003. ,
DOI : 10.1186/1479-5876-1-8
The immunologic constant of rejection, Trends in Immunology, vol.29, issue.6, pp.256-262, 2008. ,
DOI : 10.1016/j.it.2008.03.002
IMMUNOLOGICAL PARADOXES: THEORETICAL CONSIDERATIONS IN THE REJECTION OR RETENTION OF GRAFTS, TUMORS, AND NORMAL TISSUE, Annals of the New York Academy of Sciences, vol.130, issue.3287, pp.365-380, 1969. ,
DOI : 10.1002/path.1700860225
Tumour immunity: effector response to tumour and role of the microenvironment, The Lancet, vol.371, issue.9614, pp.771-783, 2008. ,
DOI : 10.1016/S0140-6736(08)60241-X
New take on comparative immunology: relevance to immunotherapy, Immunotherapy, vol.1, issue.3, pp.355-366, 2009. ,
DOI : 10.2217/imt.09.10
Antitumor vaccines , immunotherapy and the immunological constant of rejection, IDrugs, vol.12, pp.297-301, 2009. ,
Prospective molecular profiling of subcutaneous melanoma metastases suggests classifiers of immune responsiveness, Cancer Res, vol.62, pp.3581-3586, 2002. ,
DNA Microarray Analysis of Chimpanzee Liver during Acute Resolving Hepatitis C Virus Infection, Journal of Virology, vol.75, issue.15, pp.7059-7066, 2001. ,
DOI : 10.1128/JVI.75.15.7059-7066.2001
Adaptive immune responses in acute and chronic hepatitis C virus infection, Nature, vol.38, issue.7053, pp.946-952, 2005. ,
DOI : 10.1128/JVI.78.3.1575-1581.2004
Intrahepatic Gene Expression during Chronic Hepatitis C Virus Infection in Chimpanzees, Journal of Virology, vol.78, issue.24, pp.13779-13792, 2004. ,
DOI : 10.1128/JVI.78.24.13779-13792.2004
Molecular Heterogeneity in Acute Renal Allograft Rejection Identified by DNA Microarray Profiling, New England Journal of Medicine, vol.349, issue.2, pp.125-138, 2003. ,
DOI : 10.1056/NEJMoa035588
Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood, The Journal of Experimental Medicine, vol.149, issue.6 ,
DOI : 10.1136/ard.58.5.309
Systemic lupus erythematosus: all roads lead to type I interferons, Current Opinion in Immunology, vol.18, issue.6, pp.676-682, 2006. ,
DOI : 10.1016/j.coi.2006.09.014
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer, New England Journal of Medicine, vol.353, issue.25, pp.2654-2666, 2005. ,
DOI : 10.1056/NEJMoa051424
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome, Science, vol.313, issue.5795, pp.1960-1964, 2006. ,
DOI : 10.1126/science.1129139
The Adaptive Immunologic Microenvironment in Colorectal Cancer: A Novel Perspective, Cancer Research, vol.67, issue.5, pp.1883-1886, 2007. ,
DOI : 10.1158/0008-5472.CAN-06-4806
CD8 T Cell Help for Innate Antitumor Immunity, The Journal of Immunology, vol.179, issue.10, pp.6651-6662, 2007. ,
DOI : 10.4049/jimmunol.179.10.6651
URL : https://hal.archives-ouvertes.fr/hal-00297261
Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy, BMC Genomics, vol.10, issue.1, 2009. ,
DOI : 10.1186/1471-2164-10-301
Fluorescence in situ hybridization (fish): A user's guide to optimal preparation of cytologic specimens, Diagnostic Cytopathology, vol.90, issue.5, pp.486-492, 1995. ,
DOI : 10.1002/dc.2840130518
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors, Nature Reviews Immunology, vol.264, issue.9, pp.644-658, 2006. ,
DOI : 10.1038/nri1900
The IRF family, revisited, Biochimie, vol.89, issue.6-7, pp.744-753, 2007. ,
DOI : 10.1016/j.biochi.2007.01.014
Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence, Cancer Research, vol.69, issue.6, pp.2685-2693, 2009. ,
DOI : 10.1158/0008-5472.CAN-08-2654
Inflammation and cancer: back to Virchow? Lancet, pp.539-545, 2001. ,
Smoldering and polarized inflammation in the initiation and promotion of malignant disease, Cancer Cell, vol.7, issue.3, pp.211-217, 2005. ,
DOI : 10.1016/j.ccr.2005.02.013
Inflammation and cancer, Nature, vol.2, issue.6917, pp.860-867, 2002. ,
DOI : 10.1006/cyto.1996.0074
De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent, Cancer Cell, vol.7, issue.5, pp.411-423, 2005. ,
DOI : 10.1016/j.ccr.2005.04.014
Immune resistance orchestrated by the tumor microenvironment, Immunological Reviews, vol.5, issue.1, pp.131-145, 2006. ,
DOI : 10.1016/j.drup.2005.03.002
A natural history of melanoma: serial gene expression analysis, Immunology Today, vol.21, issue.12, pp.619-623, 2000. ,
DOI : 10.1016/S0167-5699(00)01724-2
Gene expression profiling of anti-cancer immune responses, Curr Op Mol Ther, vol.6, pp.288-295, 2004. ,
Spontaneous and treatment-induced cancer rejection in humans, Expert Opinion on Biological Therapy, vol.16, issue.3, pp.337-349, 2008. ,
DOI : 10.1007/s00018-007-7186-8
The immunologic aspects of poxvirus oncolytic therapy, Cancer Immunology, Immunotherapy, vol.6, issue.9, 2009. ,
DOI : 10.1007/s00262-009-0686-7
Central Memory T Cells, The Journal of Experimental Medicine, vol.2, issue.6, pp.725-735, 2004. ,
DOI : 10.1086/320996
Targeting the Chemokine Receptor CXCR3 and Its Ligand CXCL10 in the Central Nervous System: Potential Therapy for Inflammatory Demyelinating Disease?, Current Neurovascular Research, vol.1, issue.2, pp.183-190, 2004. ,
DOI : 10.2174/1567202043480143
Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells, Circulation, vol.113, issue.19, pp.2301-2312, 2006. ,
DOI : 10.1161/CIRCULATIONAHA.105.605121
Donor-Derived Ip-10 Initiates Development of Acute Allograft Rejection, The Journal of Experimental Medicine, vol.51, issue.8, pp.975-980, 2001. ,
DOI : 10.1074/jbc.271.39.24286
IP-10-induced recruitment of CXCR3+ host T cells is required for small bowel allograft rejection, Gastroenterology, vol.126, issue.3, pp.809-818, 2004. ,
DOI : 10.1053/j.gastro.2003.12.014
CXC Chemokine Receptor 3 Expression by Activated CD8+ T cells Is Associated with Survival in Melanoma Patients with Stage III Disease, Cancer Research, vol.64, issue.21, pp.7697-7701, 2004. ,
DOI : 10.1158/0008-5472.CAN-04-2059
Strong expression of the lymphoattractant C-X-C chemokine Mig is associated with heavy infiltration of T cells in human malignant melanoma, The Journal of Pathology, vol.155, issue.4, pp.552-558, 1999. ,
DOI : 10.1002/(SICI)1096-9896(199912)189:4<552::AID-PATH469>3.0.CO;2-I
CXCR3 chemokine receptor immunoreactivity in primary cutaneous malignant melanoma: correlation with clinicopathological prognostic factors, Journal of Clinical Pathology, vol.60, issue.6, pp.596-599, 2007. ,
DOI : 10.1136/jcp.2005.032144
Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment, Cancer Research, vol.69, issue.7, pp.3077-3085, 2009. ,
DOI : 10.1158/0008-5472.CAN-08-2281
Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy, Cancer Immunology, Immunotherapy, vol.24, issue.5, pp.685-691, 2007. ,
DOI : 10.1007/s00262-007-0407-z
Dendritic cell-based therapeutic cancer vaccines: what we have and what we need, Future Oncology, vol.5, issue.3, pp.379-390, 2009. ,
DOI : 10.2217/fon.09.6
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713774
Ability of Mature Dendritic Cells to Interact with Regulatory T Cells Is Imprinted during Maturation, Cancer Research, vol.68, issue.14, pp.5972-5978, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-6818
Impaired interferon signaling is a common immune defect in human cancer, Proceedings of the National Academy of Sciences, vol.106, issue.22, pp.9010-9015, 2009. ,
DOI : 10.1073/pnas.0901329106
GM-CSF/IL-3/IL-5 receptor common ?? chain (CD131) expression as a biomarker of antigen-stimulated CD8+ T cells, Journal of Translational Medicine, vol.6, issue.1, p.17, 2008. ,
DOI : 10.1186/1479-5876-6-17
Alterations in T cell receptor and signal transduction molecules in melanoma patients, Clin Cancer Res, vol.1, pp.1327-1335, 1995. ,
T cell dysfunction in cancer: Role of myeloid cells and tumor cells regulating amino acid availability and oxidative stress, Seminars in Cancer Biology, vol.16, issue.1, pp.66-72, 2006. ,
DOI : 10.1016/j.semcancer.2005.10.001
Tumor-Infiltrating Regulatory Dendritic Cells Inhibit CD8+ T Cell Function via L-Arginine Metabolism, Cancer Research, vol.69, issue.7, pp.3086-3094, 2009. ,
DOI : 10.1158/0008-5472.CAN-08-2826
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848068
JAKS AND STATS: Biological Implications, Annual Review of Immunology, vol.16, issue.1, pp.293-322, 1998. ,
DOI : 10.1146/annurev.immunol.16.1.293
Reduction in cytokine production in colorectal cancer patients: association with stage and reversal by resection, British Journal of Cancer, vol.82, issue.5, pp.1009-1012, 2000. ,
DOI : 10.1054/bjoc.1999.1034
Tumors as elusive targets of T-cell-based active immunotherapy, Trends in Immunology, vol.24, issue.6, pp.335-342, 2003. ,
DOI : 10.1016/S1471-4906(03)00116-9
Anti-viral status segregates two pancreatic adenocarcinoma molecular phenotypes with potential relevance for adenoviral gene therapy, 2009. ,
A gene expression signature associated with survival in metastatic melanoma, Journal of Translational Medicine, vol.4, issue.1, p.50, 2006. ,
DOI : 10.1186/1479-5876-4-50
Molecular classification of cutaneous malignant melanoma by gene expression: shifting from a countinuous spectrum to distinct biologic entities, Nature, vol.406, issue.6795, pp.536-840, 2000. ,
DOI : 10.1038/35020115
The gene expression signatures of melanoma progression, Proceedings of the National Academy of Sciences, vol.102, issue.17, pp.6092-6097, 2005. ,
DOI : 10.1073/pnas.0501564102
A multi-marker assay to distinguish malignant melanomas from benign nevi, Proceedings of the National Academy of Sciences, vol.106, issue.15, pp.6268-6272, 2009. ,
DOI : 10.1073/pnas.0901185106
Melanoma Genetics and Therapeutic Approaches in the 21st Century: Moving from the Benchside to the Bedside, Journal of Investigative Dermatology, vol.128, issue.11, pp.2575-2595, 2008. ,
DOI : 10.1038/jid.2008.226
Immunological detection of altered signaling molecules involved in melanoma development, Cancer and Metastasis Reviews, vol.9, issue.2, pp.357-366, 2005. ,
DOI : 10.1007/s10555-005-1583-y
Clonal Persistence and Evolution During a Decade of Recurrent Melanoma, Journal of Investigative Dermatology, vol.126, issue.6, pp.1372-1377, 2006. ,
DOI : 10.1038/sj.jid.5700193
Conservation of a core of genetic alterations over a decade of recurrent melanoma supports the melanoma stem cell hypothesis, Cancer Res, vol.68, pp.222-231, 2008. ,
Stabilization of beta -Catenin by Genetic Defects in Melanoma Cell Lines, Science, vol.275, issue.5307, pp.1790-1792, 1997. ,
DOI : 10.1126/science.275.5307.1790
Recognition of tyrosinase by tumor-infiltrating lymphocytes from a patient responding to immunotherapy [published erratum appears in Cancer Res, Jul Cancer Res, vol.1554, issue.54, pp.39523124-3126, 1994. ,
Kinetics of cytokine expression in melanoma metastases classifies immune responsiveness, International Journal of Cancer, vol.165, issue.2, pp.236-242, 2001. ,
DOI : 10.1002/ijc.1328
Cytokines and Immune Response in the Tumor Microenvironment, Journal of Immunotherapy, vol.24, issue.5, pp.392-407, 2001. ,
DOI : 10.1097/00002371-200109000-00002
The dual role of IL-10, Trends in Immunology, vol.24, issue.1, pp.36-43, 2002. ,
DOI : 10.1016/S1471-4906(02)00009-1
Elevated expressions of survivin and VEGF protein are strong independent predictors of survival in advanced nasopharyngeal carcinoma, Journal of Translational Medicine, vol.6, issue.1, p.1, 2008. ,
DOI : 10.1186/1479-5876-6-1
Focus on nasopharyngeal carcinoma, Cancer Cell, vol.5, issue.5, pp.423-428, 2004. ,
DOI : 10.1016/S1535-6108(04)00119-9
The aetiology of nasopharyngeal carcinoma, Clinical Otolaryngology and Allied Sciences, vol.2, issue.2, pp.82-92, 2001. ,
DOI : 10.1016/S0140-6736(85)90861-X
HLA and nasopharyngeal carcinoma: 30 years on, ASHI Quarterly, vol.27, pp.52-55, 2003. ,
Involvement of the Epstein???Barr Virus in the Nasopharyngeal Carcinoma Pathogenesis, Medical Oncology, vol.22, issue.2, pp.113-121, 2005. ,
DOI : 10.1385/MO:22:2:113
Nasopharyngeal carcinoma V: immunogenetic studies of Southeast Asian ethnic groups with high and low risk for the tumor, Cancer Res, vol.34, pp.1192-1195, 1974. ,
CTL Control of EBV in Nasopharyngeal Carcinoma (NPC): EBV-Specific CTL Responses in the Blood and Tumors of NPC Patients and the Antigen-Processing Function of the Tumor Cells, The Journal of Immunology, vol.165, issue.1, pp.573-582, 2000. ,
DOI : 10.4049/jimmunol.165.1.573
Adoptive transfer of autologous Epstein-Barr virus-specific cytotoxic T cells for nasopharyngeal carcinoma, International Journal of Cancer, vol.59, issue.1, pp.73-80, 2001. ,
DOI : 10.1002/ijc.1430
Immunization with Epstein-Barr virus (EBV) peptide-pulsed dendritic cells induces functional CD8+ T-cell immunity and may lead to tumor regression in patients with EBV-positive nasopharyngeal carcinoma, Cancer Res, vol.62, pp.6952-6958, 2002. ,
Interleukin-10 levels in Epstein-Barr virus-associated nasopharyngeal carcinoma, J Microbiol Immunol Infect, vol.35, pp.365-368, 2002. ,
Treatment of nasopharyngeal carcinoma with Epstein-Barr virus-specific T lymphocytes, Blood, vol.105, issue.5, pp.1898-1904, 2005. ,
DOI : 10.1182/blood-2004-07-2975
Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China, Journal of Translational Medicine, vol.6, issue.1, p.32, 2008. ,
DOI : 10.1186/1479-5876-6-32
Association between HLA-A/-B Antigens and -DRB1 Alleles and Nasopharyngeal Carcinoma in Tunisia, Oncology, vol.61, issue.1, pp.55-58, 2001. ,
DOI : 10.1159/000055353
Association of HLA Class I and II Alleles and Extended Haplotypes With Nasopharyngeal Carcinoma in Taiwan, CancerSpectrum Knowledge Environment, vol.94, issue.23, pp.1780-1789, 2002. ,
DOI : 10.1093/jnci/94.23.1780
HLA associations with nasopharyngeal carcinoma in Southern Chinese: a meta-analysis, Clinical Otolaryngology and Allied Sciences, vol.10, issue.4, pp.61-67, 2002. ,
DOI : 10.1002/(SICI)1097-0215(19970422)74:2<229::AID-IJC16>3.0.CO;2-8
Epidemiology of nasopharyngeal carcinoma, Seminars in Cancer Biology, vol.12, issue.6, pp.421-429, 2002. ,
DOI : 10.1016/S1044579X02000858
Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4, Nature Genetics, vol.31, pp.395-399, 2002. ,
DOI : 10.1038/ng932
Correlation of p21 gene codon 31 polymorphism and TNF-? gene polymorphism with nasopharyngeal carcinoma, Journal of Clinical Laboratory Analysis, vol.8, issue.3, pp.146-150, 2002. ,
DOI : 10.1002/jcla.10032
Construction of tree models for pathogenesis of nasopharyngeal carcinoma, Genes, Chromosomes and Cancer, vol.108, issue.4, pp.307-315, 2004. ,
DOI : 10.1002/gcc.20036
Pathogenesis and treatment of nasopharyngeal carcinoma, Seminars in Oncology, vol.31, issue.6, pp.794-801, 2004. ,
DOI : 10.1053/j.seminoncol.2004.09.008
Nasopharyngeal carcinoma-susceptibility locus is localized to a 132 kb segment containing HLA-A using high-resolution microsatellite mapping, International Journal of Cancer, vol.44, issue.5, pp.742-746, 2005. ,
DOI : 10.1002/ijc.20946
Chromosomal imbalances in nasopharyngeal carcinoma: a metaanalysis of comparative genomic hybridization results, Journal of Translational Medicine, vol.4, issue.1, p.4, 2006. ,
DOI : 10.1186/1479-5876-4-4
Associations between HLA Class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians, Journal of Translational Medicine, vol.5, issue.1, p.22, 2007. ,
DOI : 10.1186/1479-5876-5-22
'Racial' differences in genetic effects for complex diseases, Nature Genetics, vol.66, issue.12, pp.1312-1318, 2004. ,
DOI : 10.1038/35052543
Identification of genetic variants and gene expression relationships associated with pharmacogenes in humans, Pharmacogenetics and Genomics, vol.18, issue.6, pp.545-549, 2008. ,
DOI : 10.1097/FPC.0b013e3282fe1745
Racial and ethnic differences in cardiovascular disease risk factors: a systematic review, Ethn Dis, vol.17, pp.143-152, 2007. ,
Identification of common genetic variants that account for transcript isoform variation between human populations, Human Genetics, vol.2, issue.1, pp.81-93, 2009. ,
DOI : 10.1007/s00439-008-0601-x
Genetic analysis of genome-wide variation in human gene expression, Nature, vol.2, issue.7001, pp.743-747, 2004. ,
DOI : 10.1159/000072312
Genome-Wide Associations of Gene Expression Variation in Humans, PLoS Genetics, vol.12, issue.6, p.78, 2005. ,
DOI : 10.1371/journal.pgen.0010078.sg003
Population genomics of human gene expression, Nature Genetics, vol.142, issue.10, pp.1217-1224, 2007. ,
DOI : 10.1038/ng2142
Implications of biogeography of human populations for 'race' and medicine, Nature Genetics, vol.63, issue.11s, pp.21-27, 2004. ,
DOI : 10.1038/ng1438
Genetic instabilities in human cancers, Nature, vol.396, issue.6712, pp.643-649, 1998. ,
DOI : 10.1038/25292
Impact of gene polymorphisms on clinical outcome for stage IV melanoma patients treated with biochemotherapy: an exploratory study, Clin Cancer Res, vol.11, pp.1237-1246, 2005. ,
Prognostic Significance of Autoimmunity during Treatment of Melanoma with Interferon, New England Journal of Medicine, vol.354, issue.7, pp.709-718, 2006. ,
DOI : 10.1056/NEJMoa053007
Next Generation of Immunotherapy for Melanoma, Journal of Clinical Oncology, vol.26, issue.20, pp.3445-3455, 2008. ,
DOI : 10.1200/JCO.2007.14.6423
the Gene for Telomerase Reverse Transcriptase, in Aplastic Anemia, New England Journal of Medicine, vol.352, issue.14, pp.1413-1424, 2005. ,
DOI : 10.1056/NEJMoa042980
Functional characterization of natural telomerase mutations found in patients with hematologic disorders, Blood, vol.109, issue.2, pp.524-532, 2007. ,
DOI : 10.1182/blood-2006-07-035089
Telomere maintenance and human bone marrow failure, Blood, vol.111, issue.9, pp.4446-4455, 2008. ,
DOI : 10.1182/blood-2007-08-019729
Racial Differences in Response Rates to Consensus Interferon in HCV Infected Patients Naive to Previous Therapy, Journal of Clinical Gastroenterology, vol.38, issue.7, pp.599-604, 2004. ,
DOI : 10.1097/00004836-200408000-00012
Peginterferon and Ribavirin Treatment in African American and Caucasian American Patients With Hepatitis C Genotype 1, Gastroenterology, vol.131, issue.2, pp.470-477, 2006. ,
DOI : 10.1053/j.gastro.2006.06.008
Association of single nucleotide polymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the response to interferon therapy for chronic hepatitis C, Journal of Hepatology, vol.49, issue.2, pp.184-191, 2008. ,
DOI : 10.1016/j.jhep.2008.04.011
Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans, Genes and Immunity, vol.54, issue.3, pp.187-194, 2008. ,
DOI : 10.1038/gene.2008.4
High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups, Arthritis & Rheumatism, vol.4, issue.4, pp.1085-1095, 2009. ,
DOI : 10.1002/art.24387
The GNB3 C825T polymorphism affects response to HCV therapy with pegylated interferon in HCV/HIV co-infected but not in HCV mono-infected patients, Journal of Hepatology, vol.47, issue.3, pp.348-355, 2007. ,
DOI : 10.1016/j.jhep.2007.04.008
GNB3 C825T polymorphism and response to interferon-alfa/ribavirin treatment in patients with hepatitis C virus genotype 1 (HCV-1) infection, Journal of Hepatology, vol.43, issue.3, pp.388-393, 2005. ,
DOI : 10.1016/j.jhep.2005.03.020
The Genetic Structure and History of Africans and African Americans, Science, vol.324, issue.5930, 2009. ,
DOI : 10.1126/science.1172257
Tumor Immunobiological Differences in Prostate Cancer between African-American and European-American Men, Cancer Research, vol.68, issue.3, pp.927-936, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-2608
Differences in the Tumor Microenvironment between African-American and European-American Breast Cancer Patients, PLoS ONE, vol.64, issue.2, p.4531, 2009. ,
DOI : 10.1371/journal.pone.0004531.s005
Cancer Statistics, 2008, Cancer statistics, pp.71-96, 2008. ,
DOI : 10.3322/CA.2007.0010
An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer, Proceedings of the National Academy of Sciences, vol.105, issue.47, pp.18490-18495, 2008. ,
DOI : 10.1073/pnas.0809242105
Systematic Evaluation of Genetic Variants in the Inflammation Pathway and Risk of Lung Cancer, Cancer Research, vol.67, issue.13, pp.6520-6527, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-0370
Polymorphisms in Inflammation Genes and Bladder Cancer: From Initiation to Recurrence, Progression, and Survival, Journal of Clinical Oncology, vol.23, issue.24, pp.5746-5756, 2005. ,
DOI : 10.1200/JCO.2005.01.598
Adjuvant therapy of melanoma with interferon: lessons of the past decade, Journal of Translational Medicine, vol.6, issue.1, p.62, 2008. ,
DOI : 10.1186/1479-5876-6-62
Biomarkers of Therapeutic Response in Melanoma and Renal Cell Carcinoma: Potential Inroads to Improved Immunotherapy, Journal of Clinical Oncology, vol.27, issue.16, pp.2583-2585, 2009. ,
DOI : 10.1200/JCO.2008.21.1540
Multiplex Analysis of Serum Cytokines in Melanoma Patients Treated with Interferon-??2b, Clinical Cancer Research, vol.13, issue.8, pp.2422-2428, 2007. ,
DOI : 10.1158/1078-0432.CCR-06-1805
Changes in circulating VEGF- A levels related to clinical response during biochemotherapy in metastatic malignant melanoma, J Clin Oncol, vol.22, p.717, 2004. ,
Pretreatment serum interleukin-6 concentration as a prognostic factor of overall survival in metastatic malignant melanoma patients treated with biochemotherapy: a retrospective study, Melanoma Research, vol.15, issue.3, pp.199-204, 2005. ,
DOI : 10.1097/00008390-200506000-00009
Factors Associated With Response to High-Dose Interleukin-2 in Patients With Metastatic Melanoma, Journal of Clinical Oncology, vol.19, issue.15, pp.3477-3482, 2001. ,
DOI : 10.1200/JCO.2001.19.15.3477
Neoadjuvant Treatment of Regional Stage IIIB Melanoma With High-Dose Interferon Alfa-2b Induces Objective Tumor Regression in Association With Modulation of Tumor Infiltrating Host Cellular Immune Responses, Journal of Clinical Oncology, vol.24, issue.19, pp.3164-3171, 2006. ,
DOI : 10.1200/JCO.2005.05.2498
Carbonic Anhydrase IX Expression Predicts Outcome of Interleukin 2 Therapy for Renal Cancer, Clinical Cancer Research, vol.11, issue.10, pp.3714-3721, 2005. ,
DOI : 10.1158/1078-0432.CCR-04-2019
The Pathway to Biomarker Discovery: Carbonic Anhydrase IX and the Prediction of Immune Responsiveness, Clinical Cancer Research, vol.11, issue.10, pp.3601-3603, 2005. ,
DOI : 10.1158/1078-0432.CCR-05-0475
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients, Proceedings of the National Academy of Sciences, vol.100, issue.8, pp.4712-4717, 2003. ,
DOI : 10.1073/pnas.0830997100
Prostate Cancer Vaccines, BioDrugs, vol.41, issue.14S, pp.71-84, 2008. ,
DOI : 10.2165/00063030-200822020-00001
Emerging therapies in castrate-resistant prostate cancer, Current Opinion in Oncology, vol.21, issue.3, pp.260-265, 2009. ,
DOI : 10.1097/CCO.0b013e32832a1868
MFG-E8???mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF, Journal of Clinical Investigation, vol.117, issue.7, pp.1902-1913, 2007. ,
DOI : 10.1172/JCI30966DS1
Milk Fat Globule EGF-8 Promotes Melanoma Progression through Coordinated Akt and Twist Signaling in the Tumor Microenvironment, Cancer Research, vol.68, issue.21, pp.8889-8898, 2008. ,
DOI : 10.1158/0008-5472.CAN-08-2147
Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines, Immunological Reviews, vol.169, issue.1, pp.287-298, 2008. ,
DOI : 10.1084/jem.20051848
Generation in vivo of peptide-specific cytotoxic T cells and presence of regulatory T cells during vaccination with hTERT (class I and II) peptide-pulsed DCs, Journal of Translational Medicine, vol.7, issue.1, p.18, 2009. ,
DOI : 10.1186/1479-5876-7-18
MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma, Clin Cancer Res, vol.9, pp.947-954, 2003. ,
The Translational Research Working Group Developmental Pathways: Introduction and Overview, Clinical Cancer Research, vol.14, issue.18, pp.5664-5671, 2008. ,
DOI : 10.1158/1078-0432.CCR-08-1268
Translational Research Working Group Developmental Pathway for Immune Response Modifiers, Clinical Cancer Research, vol.14, issue.18, pp.5692-5699, 2008. ,
DOI : 10.1158/1078-0432.CCR-08-1266
The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research, Clinical Cancer Research, vol.15, issue.17, 2009. ,
DOI : 10.1158/1078-0432.CCR-09-0737
Molecular pathological approaches to human tumor immunology, Pathology International, vol.133, issue.4, pp.205-217, 2009. ,
DOI : 10.1111/j.1440-1827.2009.02353.x
Analysis of peripheral and local anti-tumor immune response in esophageal cancer patients after NY-ESO-1 protein vaccination, International Journal of Cancer, vol.56, issue.10, pp.2362-2369, 2008. ,
DOI : 10.1002/ijc.23810
Adjuvant Therapy With the Monoclonal Antibody Edrecolomab Plus Fluorouracil-Based Therapy Does Not Improve Overall Survival of Patients With Stage III Colon Cancer, Journal of Clinical Oncology, vol.27, issue.12, pp.1941-1947, 2009. ,
DOI : 10.1200/JCO.2008.18.5710
EpCAM an immunotherapeutic target for gastrointestinal malignancy: current experience and future challenges, British Journal of Cancer, vol.5, issue.2, pp.1013-1019, 2007. ,
DOI : 10.1016/j.humpath.2003.08.026
Antibody-Mediated Targeting of an Adenovirus Vector Modified To Contain a Synthetic Immunoglobulin G-Binding Domain in the Capsid, Journal of Virology, vol.77, issue.3, pp.2093-2104, 2003. ,
DOI : 10.1128/JVI.77.3.2093-2104.2003
Histone Deacetylase Inhibitor FK228 Activates Tumor Suppressor Prdx1 with Apoptosis Induction in Esophageal Cancer Cells, Clinical Cancer Research, vol.11, issue.21, pp.7945-7952, 2005. ,
DOI : 10.1158/1078-0432.CCR-05-0840
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer, Proceedings of the National Academy of Sciences, vol.104, issue.47, pp.18654-18659, 2007. ,
DOI : 10.1073/pnas.0704652104
Inflammation-Related Aberrant Patterns of DNA Methylation: Detection and Role in Epigenetic Deregulation of Cancer Cell Transcriptome, Methods Mol Biol, vol.512, pp.55-69, 2009. ,
DOI : 10.1007/978-1-60327-530-9_5