Adverse childhood environment and late-life cognitive functioning. - Archive ouverte HAL Access content directly
Journal Articles International Journal of Geriatric Psychiatry Year : 2011

Adverse childhood environment and late-life cognitive functioning.

(1) , (1) , (1, 2) , (1, 3) , (1, 4) , (1, 5) , (1)
1
2
3
4
5

Abstract

Objective: Clinical studies suggest that childhood maltreatment may cause nervous system changes and consequent cognitive disorder. The persistence of this association in late-life is examined. Methods: Cognitive functioning and childhood events were examined in 1282 persons over 65 years, taking into account proximal competing causes of poor cognitive performance. Results: 91 % of participants experienced at least one adverse childhood event, of these 14.7 % severe events. Sharing of parental problems and, for women, loss of a parent, were associated with poorer verbal retrieval whereas being sent to a foster home or mistreatment by schoolmates was associated with poorer visuospatial memory. Severe abuse was associated with a lower risk of cognitive impairment on some tests suggesting a resilience factor. Positive childhood environment was protective although only for non-carriers of the ApoE epsilon4 allele on the central executive task. Conclusions: Some adverse childhood events continue to have a negative effect on later-life cognitive performance, while some more severe acute events may have the opposite effect, underlying the necessity to consider events individually and not as global test scores.
Fichier principal
Vignette du fichier
Ritchie_Int_J_Geriatr_Psy_26_503.pdf (235.5 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

inserm-00584172 , version 1 (07-10-2011)

Identifiers

Cite

Karen Ritchie, Isabelle Jaussent, Robert Stewart, Anne-Marie Dupuy, Philippe Courtet, et al.. Adverse childhood environment and late-life cognitive functioning.: Adverse childhood environment and late-life cognitive functioning. International Journal of Geriatric Psychiatry, 2011, 26 (5), pp.503-10. ⟨10.1002/gps.2553⟩. ⟨inserm-00584172⟩
324 View
844 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More