The thalamic reticular nucleus: structure, function and concept. - Archive ouverte HAL Access content directly
Journal Articles Brain Researchearch Reviews / Brain Research Brain Research Rev; BRAIN RESEARCH BRAIN RESEARCH REVIEWS Year : 2004

The thalamic reticular nucleus: structure, function and concept.

(1)
1

Abstract

On the basis of theoretical, anatomical, psychological and physiological considerations, Francis Crick (1984) proposed that, during selective attention, the thalamic reticular nucleus (TRN) controls the internal attentional searchlight that simultaneously highlights all the neural circuits called on by the object of attention. In other words, he submitted that during either perception, or the preparation and execution of any cognitive and/or motor task, the TRN sets all the corresponding thalamocortical (TC) circuits in motion. Over the last two decades, behavioural, electrophysiological, anatomical and neurochemical findings have been accumulating, supporting the complex nature of the TRN and raising questions about the validity of this speculative hypothesis. Indeed, our knowledge of the actual functioning of the TRN is still sprinkled with unresolved questions. Therefore, the time has come to join forces and discuss some recent cellular and network findings concerning this diencephalic GABAergic structure, which plays important roles during various states of consciousness. On the whole, the present critical survey emphasizes the TRN's complexity, and provides arguments combining anatomy, physiology and cognitive psychology.

Dates and versions

inserm-00560827 , version 1 (30-01-2011)

Identifiers

Cite

Didier Pinault. The thalamic reticular nucleus: structure, function and concept.. Brain Researchearch Reviews / Brain Research Brain Research Rev; BRAIN RESEARCH BRAIN RESEARCH REVIEWS, 2004, 46 (1), pp.1-31. ⟨10.1016/j.brainresrev.2004.04.008⟩. ⟨inserm-00560827⟩

Collections

INSERM
65 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More