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Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.

Abstract : New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.
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https://www.hal.inserm.fr/inserm-00559554
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Submitted on : Tuesday, January 25, 2011 - 6:18:21 PM
Last modification on : Friday, July 17, 2020 - 8:34:03 AM
Long-term archiving on: : Saturday, December 3, 2016 - 12:33:15 AM

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Mathieu Galibert, Lucie Sancey, Olivier Renaudet, Jean-Luc Coll, Pascal Dumy, et al.. Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.. Organic and Biomolecular Chemistry, Royal Society of Chemistry, 2010, 8 (22), pp.5133-8. ⟨10.1039/c0ob00070a⟩. ⟨inserm-00559554⟩

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