Etidronate inhibits human osteoblast apoptosis by inhibition of pro-apoptotic factor(s) produced by activated T cells, Journal of Laboratory and Clinical Medicine, vol.136, issue.5, pp.344-54, 2000. ,
DOI : 10.1067/mlc.2000.109757
Response of cortical bone to antiresorptive agents and parathyroid hormone in aged ovariectomized rats, Bone, vol.16, issue.2, pp.247-53, 1995. ,
DOI : 10.1016/8756-3282(94)00036-Y
Alendronate increases skeletal mass of growing rats during unloading by inhibiting resorption of calcified cartilage, Journal of Bone and Mineral Research, vol.6, issue.11, pp.1777-87, 1994. ,
DOI : 10.1002/jbmr.5650091115
The Effects of Parathyroid Hormone and Alendronate Alone or in Combination in Postmenopausal Osteoporosis, New England Journal of Medicine, vol.349, issue.13, pp.1207-1222, 2003. ,
DOI : 10.1056/NEJMoa031975
Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women, Bone, vol.27, issue.5, pp.687-94, 2000. ,
DOI : 10.1016/S8756-3282(00)00376-8
Ten Years' Experience with Alendronate for Osteoporosis in Postmenopausal Women, New England Journal of Medicine, vol.350, issue.12, pp.1189-99, 2004. ,
DOI : 10.1056/NEJMoa030897
Does early PTH treatment compromise bone strength? The balance between remodeling, porosity, bone mineral, and bone size, Current Osteoporosis Reports, vol.19, issue.1, pp.19-24, 2005. ,
DOI : 10.1007/s11914-005-0023-9
Tissue mineralization is increased following 1-year treatment with high doses of bisphosphonates in dogs, Bone, vol.33, issue.6, pp.960-969, 2003. ,
DOI : 10.1016/j.bone.2003.08.004
Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis., Journal of Clinical Investigation, vol.100, issue.6, pp.1475-80, 1997. ,
DOI : 10.1172/JCI119668
Identification of a novel phosphonocarboxylate inhibitor of rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages, J Biol Chem, vol.276, pp.48213-48235, 2001. ,
Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo, Bone, vol.37, issue.3, pp.349-58, 2005. ,
DOI : 10.1016/j.bone.2005.04.021
Resorbing osteoclasts increase the availability of mineral-bound bisphosphonates to nonresorbing cells, J Bone Miner Res, vol.20, p.260, 2005. ,
Risedronate and other nitrogen-containing bisphosphonates are efficiently internalized from mineralized surfaces by osteoclasts, but not other cell types, in vitro and in vivo, Bone, vol.36, p.303, 2005. ,
Differential Effects of Teriparatide on BMD After Treatment With Raloxifene or Alendronate, Journal of Bone and Mineral Research, vol.18, issue.5, pp.745-51, 2004. ,
DOI : 10.1359/jbmr.040117
The Effects of Parathyroid Hormone, Alendronate, or Both in Men with Osteoporosis, New England Journal of Medicine, vol.349, issue.13, pp.1216-1242, 2003. ,
DOI : 10.1056/NEJMoa035725
Effects of Bisphosphonates on the Osteoclast Mevalonate Pathway, Endocrinology, vol.141, issue.12, pp.4793-4799, 2000. ,
DOI : 10.1210/endo.141.12.7921
The degree of mineralization is a determinant of bone strength: a study on human calcanei, Bone, vol.34, issue.5, pp.783-792, 2004. ,
DOI : 10.1016/j.bone.2003.12.012
URL : https://hal.archives-ouvertes.fr/inserm-00557244
Long-term effects of neridronate on human osteoblastic cell cultures, Bone, vol.35, issue.4, pp.859-69, 2004. ,
DOI : 10.1016/j.bone.2004.06.001
Bisphosphonates influence the proliferation and the maturation of normal human osteoblasts, Journal of Endocrinological Investigation, vol.104, issue.6, pp.539-585, 2002. ,
DOI : 10.1007/BF03345497
Effect of alendronate on cultured normal human osteoblasts, Bone, vol.22, issue.3, pp.233-242, 1998. ,
DOI : 10.1016/S8756-3282(97)00270-6
The blunting of the bone anabolic response to PTH observed after frequently dosed bisphosphonates in rats may be explained by inhibition of farnesyl diphosphate synthase in osteoblasts, J Bone Miner Res, vol.20, p.78, 2005. ,
PTH and interactions with bisphosphonates, J Muscloskel Neuron Interact, vol.1, pp.53-59, 2000. ,
Bisphosphonates Stimulate Formation of Osteoblast Precursors and Mineralized Nodules in Murine and Human Bone Marrow Cultures In Vitro and Promote Early Osteoblastogenesis in Young and Aged Mice In Vivo, Bone, vol.22, issue.5, pp.455-61, 1998. ,
DOI : 10.1016/S8756-3282(98)00033-7
Early histomorphometric changes in response to parathyroid hormone therapy in osteoporosis: Evidence for de novo bone formation on quiescent cancellous surfaces, Bone, vol.14, issue.3, pp.523-530, 1993. ,
DOI : 10.1016/8756-3282(93)90190-L
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo, Journal of Bone and Mineral Research, vol.11, issue.2, pp.1478-87, 1995. ,
DOI : 10.1002/jbmr.5650101008
Osteoblast proliferation and maturation by bisphosphonates, Biomaterials, vol.25, issue.18, pp.4105-4120, 2004. ,
DOI : 10.1016/j.biomaterials.2003.11.024
Diphosphonates inhibit human osteoblast secretion and proliferation, Metabolism, vol.38, issue.2, pp.184-191, 1989. ,
DOI : 10.1016/0026-0495(89)90260-6
Parathyroid Hormone plus Alendronate ??? A Combination That Does Not Add Up, New England Journal of Medicine, vol.349, issue.13, pp.1277-1286, 2003. ,
DOI : 10.1056/NEJMe038143
Short term response to parathyroid hormone (1?34 hPTH) in human iliac crest bone using a unique quadruple (double double) tetracycline labeling regimen and single biopsy, J Bone Miner Res, vol.18, p.54, 2003. ,
Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line, British Journal of Cancer, vol.84, issue.7, pp.951-959, 2001. ,
DOI : 10.1054/bjoc.2000.1679
Bone mineral density reflects bone mass but also the degree of mineralization of bone: Therapeutic implications, Bone, vol.21, issue.5, pp.373-380, 1997. ,
DOI : 10.1016/S8756-3282(97)00170-1
A possible mechanism of the specific action of bisphosphonates on osteoclasts: Tiludronate preferentially affects polarized osteoclasts having ruffled borders, Bone, vol.17, issue.2, pp.137-181, 1995. ,
DOI : 10.1016/S8756-3282(95)00150-6
Osteoprotegerin Regulates Bone Formation through a Coupling Mechanism with Bone Resorption, Endocrinology, vol.144, issue.12, pp.5441-5450, 2003. ,
DOI : 10.1210/en.2003-0717
Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee, Journal of Bone and Mineral Research, vol.10, issue.6, pp.595-610, 1987. ,
DOI : 10.1002/jbmr.5650020617
Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin, Journal of Clinical Investigation, vol.104, issue.10, pp.1363-74, 1999. ,
DOI : 10.1172/JCI6800
Normal bone histomorphometry and 3D microarchitecture after 10 years alendronate treatment of postmenopausal women, J Bone Miner Res, vol.19, p.45, 2004. ,
Bisphosphonates directly regulate cell proliferation, differentiation , and gene expression in human osteoblasts, Cancer Res, vol.60, pp.6001-6008, 2000. ,
Bisphosphonates: mechanisms of action., Journal of Clinical Investigation, vol.97, issue.12, pp.2692-2698, 1996. ,
DOI : 10.1172/JCI118722
Long-term efficacy of risedronate: a 5-year placebo-controlled clinical experience??????This study was sponsored by Procter & Gamble Pharmaceuticals, Cincinnati, Ohio, and Aventis Pharma, Bridgewater, New Jersey., Bone, vol.32, issue.2, pp.120-126, 2003. ,
DOI : 10.1016/S8756-3282(02)00946-8
The Role of Geranylgeranylation in Bone Resorption and Its Suppression by Bisphosphonates in Fetal Bone Explants In Vitro: A Clue to the Mechanism of Action of Nitrogen-Containing Bisphosphonates, Journal of Bone and Mineral Research, vol.22, issue.Suppl, pp.722-731, 1999. ,
DOI : 10.1359/jbmr.1999.14.5.722
Bisphosphonates Pamidronate and Zoledronic Acid Stimulate Osteoprotegerin Production by Primary Human Osteoblasts, Biochemical and Biophysical Research Communications, vol.291, issue.3, pp.680-686, 2002. ,
DOI : 10.1006/bbrc.2002.6510
Effects of bisphosphonates on proliferation and osteoblast differentiation of human bone marrow stromal cells, Biomaterials, vol.26, issue.34, pp.6941-6950, 2005. ,
DOI : 10.1016/j.biomaterials.2005.04.059
Anabolic effects of parathyroid hormone on cortical bone in ovariectomized rats, Bone, vol.15, issue.1, pp.51-59, 1994. ,
DOI : 10.1016/8756-3282(94)90891-5
Acid extrusion is induced by osteoclast attachment to bone. Inhibition by alendronate and calcitonin., Journal of Clinical Investigation, vol.96, issue.5, pp.2277-83, 1995. ,
DOI : 10.1172/JCI118283