Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter, Embo J, vol.6, issue.13, pp.4073-4081, 1987. ,
E4F1 Is an Atypical Ubiquitin Ligase that Modulates p53 Effector Functions Independently of Degradation, Cell, vol.127, issue.4, pp.775-788, 2006. ,
DOI : 10.1016/j.cell.2006.09.031
p53 is involved in the p120E4F-mediated growth arrest, Oncogene, vol.19, issue.2, pp.188-199, 2000. ,
DOI : 10.1038/sj.onc.1203250
Association of p14ARF with the p120E4FTranscriptional Repressor Enhances Cell Cycle Inhibition, Journal of Biological Chemistry, vol.278, issue.7, pp.4981-4989, 2003. ,
DOI : 10.1074/jbc.M210978200
E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells, Genes & Development, vol.20, issue.15, pp.2110-2120, 2006. ,
DOI : 10.1101/gad.1453406
The LIM-only protein FHL2 is a negative regulator of E4F1, Oncogene, vol.24, issue.40, pp.5475-5484, 2006. ,
DOI : 10.1038/sj.onc.1209567
Identification of the E1A-Regulated Transcription Factor p120E4F as an Interacting Partner of the RASSF1A Candidate Tumor Suppressor Gene, Cancer Research, vol.64, issue.1, pp.102-107, 2004. ,
DOI : 10.1158/0008-5472.CAN-03-2622
pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F, Proceedings of the National Academy of Sciences, vol.97, issue.14, pp.7738-7743, 2000. ,
DOI : 10.1073/pnas.130198397
Transcriptional Activation of the Cyclin A Gene by the Architectural Transcription Factor HMGA2, Molecular and Cellular Biology, vol.23, issue.24, pp.9104-9116, 2003. ,
DOI : 10.1128/MCB.23.24.9104-9116.2003
Dual Roles of Smad Proteins in the Conversion from Myoblasts to Osteoblastic Cells by Bone Morphogenetic Proteins, Journal of Biological Chemistry, vol.285, issue.20, pp.15577-15586 ,
DOI : 10.1074/jbc.M109.028019
The E4F Protein Is Required for Mitotic Progression during Embryonic Cell Cycles, Molecular and Cellular Biology, vol.24, issue.14, pp.6467-6475, 2004. ,
DOI : 10.1128/MCB.24.14.6467-6475.2004
Epidermal homeostasis: a balancing act of stem cells in the skin, Nature Reviews Molecular Cell Biology, vol.8, issue.3, pp.207-217, 2009. ,
DOI : 10.1038/nrm2636
Epithelial Stem Cells: A Folliculocentric View, Journal of Investigative Dermatology, vol.126, issue.7, pp.1459-1468, 2006. ,
DOI : 10.1038/sj.jid.5700376
Controlling skin morphogenesis: hope and despair, Current Opinion in Biotechnology, vol.14, issue.5, pp.520-525, 2003. ,
DOI : 10.1016/j.copbio.2003.09.005
Notch tumor suppressor function, Oncogene, vol.126, issue.38, pp.5115-5123, 2008. ,
DOI : 10.1182/blood-2005-01-0355
p63 in epithelial development, Cellular and Molecular Life Sciences, vol.65, issue.20, pp.3126-3133, 2008. ,
DOI : 10.1007/s00018-008-8119-x
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context, Cancer Cell, vol.4, issue.2, pp.111-120, 2003. ,
DOI : 10.1016/S1535-6108(03)00191-0
A keratin K5Cre transgenic line appropriate for tissue-specific or generalized cre-mediated recombination, genesis, vol.2, issue.1, pp.52-57, 2004. ,
DOI : 10.1002/gene.20025
Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes, The Journal of Cell Biology, vol.98, issue.4, pp.1397-1406933, 1984. ,
DOI : 10.1083/jcb.98.4.1397
NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells, Cell, vol.132, issue.2, pp.299-310, 2008. ,
DOI : 10.1016/j.cell.2007.11.047
Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells, Molecular Biology of the Cell, vol.20, issue.3, pp.882-890, 2009. ,
DOI : 10.1091/mbc.E08-07-0731
Deregulated expression of c-Myc depletes epidermal stem cells, Nature Genetics, vol.28, issue.2, pp.165-168, 2001. ,
DOI : 10.1038/88889
c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny, Current Biology, vol.11, issue.8, pp.558-568, 2001. ,
DOI : 10.1016/S0960-9822(01)00154-3
Three clonal types of keratinocyte with different capacities for multiplication., Proceedings of the National Academy of Sciences, vol.84, issue.8, pp.2302-2306, 1987. ,
DOI : 10.1073/pnas.84.8.2302
Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche, Cell, vol.118, issue.5, pp.635-648, 2004. ,
DOI : 10.1016/j.cell.2004.08.012
Capturing and profiling adult hair follicle stem cells, Nature Biotechnology, vol.22, issue.4, pp.411-417, 2004. ,
DOI : 10.1038/nbt950
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis, Development, vol.130, issue.21, pp.5241-5255, 2003. ,
DOI : 10.1242/dev.00703
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus, Nature, vol.397, issue.6715, pp.164-168, 1999. ,
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a, Nature, vol.439, issue.7110, pp.421-426, 2006. ,
DOI : 10.1038/nature05159
p16INK4a induces an age-dependent decline in islet regenerative potential, Nature, vol.88, issue.7110, pp.453-457, 2006. ,
DOI : 10.1038/nature05092
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing, Nature, vol.413, issue.7110, pp.448-452, 2006. ,
DOI : 10.1038/nature05091
Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16Ink4a and Arf, Genes & Development, vol.22, issue.22, pp.3115-3120, 2008. ,
DOI : 10.1101/gad.1715808
Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf, The EMBO Journal, vol.6, issue.13, pp.1904-1915, 2009. ,
DOI : 10.1073/pnas.2536808100
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice, Genes & Development, vol.23, issue.17, pp.2060-2075, 2009. ,
DOI : 10.1101/gad.543509
A p53-Dependent Response Limits Epidermal Stem Cell Functionality and Organismal Size in Mice with Short Telomeres, PLoS ONE, vol.443, issue.3, pp.4934-4971, 2009. ,
DOI : 10.1371/journal.pone.0004934.s002
TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance, Cell Stem Cell, vol.5, issue.1, pp.64-75, 2009. ,
DOI : 10.1016/j.stem.2009.04.003
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors, Nature, vol.351, issue.7192, pp.228-232, 2008. ,
DOI : 10.1038/nature06869
p53 regulates the self-renewal and differentiation of neural precursors, Neuroscience, vol.158, issue.4, pp.1378-1389, 2009. ,
DOI : 10.1016/j.neuroscience.2008.10.052
The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells, Cell, vol.138, issue.6, pp.1083-1095, 2009. ,
DOI : 10.1016/j.cell.2009.06.048
A single type of progenitor cell maintains normal epidermis, Nature, vol.44, issue.7132, pp.185-189, 2007. ,
DOI : 10.1038/nature05574
Asymmetric cell divisions promote stratification and differentiation of mammalian skin, Nature, vol.166, issue.7056, pp.275-280, 2005. ,
DOI : 10.1091/mbc.E03-04-0212
Role of the INK4a Locus in Tumor Suppression and Cell Mortality, Cell, vol.85, issue.1, pp.27-37, 1996. ,
DOI : 10.1016/S0092-8674(00)81079-X
New techniques for the grafting of cultured, 1988. ,