F. Radtke, H. Clevers, and O. Riccio, From Gut Homeostasis to Cancer, Current Molecular Medicine, vol.6, issue.3, pp.275-89, 2006.
DOI : 10.2174/156652406776894527

O. Sansom, K. Reed, and A. Hayes, Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration, Genes & Development, vol.18, issue.12, pp.1385-90, 2004.
DOI : 10.1101/gad.287404

P. Andreu, S. Colnot, and C. Godard, Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine, Development, vol.132, issue.6, pp.1443-51, 2005.
DOI : 10.1242/dev.01700

S. Artavanis-tsakonas, M. Rand, and R. Lake, Notch Signaling: Cell Fate Control and Signal Integration in Development, Science, vol.284, issue.5415, pp.770-776, 1999.
DOI : 10.1126/science.284.5415.770

J. Jensen, E. Pedersen, and P. Galante, Control of endodermal endocrine development by Hes-1, Nat Genet, vol.24, pp.36-44, 2000.

Q. Yang, N. Bermingham, and M. Finegold, Requirement of Math1 for Secretory Cell Lineage Commitment in the Mouse Intestine, Science, vol.294, issue.5549, pp.2155-2163, 2001.
DOI : 10.1126/science.1065718

J. Van-es, M. Van-gijn, and O. Riccio, Notch/??-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells, Nature, vol.435, issue.7044, pp.959-63, 2005.
DOI : 10.1038/nature03659

S. Fre, M. Huyghe, and P. Mourikis, Notch signals control the fate of immature progenitor cells in the intestine, Nature, vol.435, issue.7044, pp.964-972, 2005.
DOI : 10.1038/nature03589

S. Fre, S. Pallavi, and M. Huyghe, Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine, Proceedings of the National Academy of Sciences, vol.106, issue.15, pp.6309-6323, 2009.
DOI : 10.1073/pnas.0900427106

S. Colnot, M. Niwa-kawakita, and G. Hamard, Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers, Laboratory Investigation, vol.61, issue.12, pp.1619-1649, 2004.
DOI : 10.1038/labinvest.3700180

A. Weng, A. Ferrando, and W. Lee, Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia, Science, vol.306, issue.5694, pp.269-71, 2004.
DOI : 10.1126/science.1102160

V. Rodilla, A. Villanueva, and A. Obrador-hevia, Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer, Proceedings of the National Academy of Sciences, vol.106, issue.15, pp.6315-6335, 2009.
DOI : 10.1073/pnas.0813221106

P. Hatzis, L. Van-der-flier, and M. Van-driel, Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells, Molecular and Cellular Biology, vol.28, issue.8, pp.2732-2776, 2008.
DOI : 10.1128/MCB.02175-07

H. Han, K. Tanigaki, and N. Yamamoto, Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision, International Immunology, vol.14, issue.6, pp.637-682, 2002.
DOI : 10.1093/intimm/dxf030

O. Riccio, M. Van-gijn, and A. Bezdek, Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2, EMBO reports, vol.52, issue.4, pp.377-83, 2008.
DOI : 10.1126/science.1065718

P. Andreu, G. Peignon, and C. Slomianny, A genetic study of the role of the Wnt/??-catenin signalling in Paneth cell differentiation, Developmental Biology, vol.324, issue.2, pp.288-96, 2008.
DOI : 10.1016/j.ydbio.2008.09.027

N. Barker, R. Ridgway, and J. Van-es, Crypt stem cells as the cells-of-origin of intestinal cancer, Nature, vol.104, issue.7229, pp.608-619, 2009.
DOI : 10.1038/nature07602

M. Aragaki, K. Tsuchiya, and R. Okamoto, Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer, Biochemical and Biophysical Research Communications, vol.368, issue.4, pp.923-932, 2008.
DOI : 10.1016/j.bbrc.2008.02.011

K. Tsuchiya, T. Nakamura, and R. Okamoto, Reciprocal Targeting of Hath1 and ??-Catenin by Wnt Glycogen Synthase Kinase 3?? in Human Colon Cancer, Gastroenterology, vol.132, issue.1, pp.208-228, 2007.
DOI : 10.1053/j.gastro.2006.10.031

A. Helms, A. Abney, and N. Ben-arie, Autoregulation and multiple enhancers control Math1 expression in the developing nervous system, Development, vol.127, pp.1185-96, 2000.

E. Park, H. Oh, J. Gum, and . Jr, HATH1 Expression in Mucinous Cancers of the Colorectum and Related Lesions, Clinical Cancer Research, vol.12, issue.18, pp.5403-5413, 2006.
DOI : 10.1158/1078-0432.CCR-06-0573

W. Bossuyt, A. Kazanjian, D. Geest, and N. , Atonal homolog 1 Is a Tumor Suppressor Gene, PLoS Biology, vol.100, issue.2, p.39, 2009.
DOI : 10.1371/journal.pbio.1000039.sg012

N. Shroyer, M. Helmrath, and V. Wang, Intestine-Specific Ablation of Mouse atonal homolog 1 (Math1) Reveals a Role in Cellular Homeostasis, Gastroenterology, vol.132, issue.7, pp.2478-88, 2007.
DOI : 10.1053/j.gastro.2007.03.047

M. Reedijk, S. Odorcic, and H. Zhang, Activation of Notch signaling in human colon adenocarcinoma, Int J Oncol, vol.33, pp.1223-1232, 2008.

F. Kubo and S. Nakagawa, Hairy1 acts as a node downstream of Wnt signaling to maintain retinal stem cell-like progenitor cells in the chick ciliary marginal zone, Development, vol.136, issue.11, pp.1823-1856, 2009.
DOI : 10.1242/dev.029272

W. Ingram, K. Mccue, and T. Tran, Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling, Oncogene, vol.163, issue.10, pp.1489-500, 2008.
DOI : 10.1073/pnas.082092399

C. Aguilera, R. Hoya-arias, and G. Haegeman, Recruitment of I??B?? to the hes1 promoter is associated with transcriptional repression, Proceedings of the National Academy of Sciences, vol.101, issue.47, pp.16537-16579, 2004.
DOI : 10.1073/pnas.0404429101

M. Stockhausen, J. Sjölund, and H. Axelson, Regulation of the Notch target gene Hes-1 by TGF?? induced Ras/MAPK signaling in human neuroblastoma cells, Experimental Cell Research, vol.310, issue.1, pp.218-246, 2005.
DOI : 10.1016/j.yexcr.2005.07.011

J. Pannequin, C. Bonnans, and N. Delaunay, The Wnt Target Jagged-1 Mediates the Activation of Notch Signaling by Progastrin in Human Colorectal Cancer Cells, Cancer Research, vol.69, issue.15, pp.6065-73, 2009.
DOI : 10.1158/0008-5472.CAN-08-2409

A. Raafat, S. Lawson, and S. Bargo, Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis, Oncogene, vol.105, issue.2, pp.219-249, 2009.
DOI : 10.1038/onc.2008.379

R. Kageyama, T. Ohtsuka, and T. Kobayashi, The Hes gene family: repressors and oscillators that orchestrate embryogenesis, Development, vol.134, issue.7, pp.1243-51, 2007.
DOI : 10.1242/dev.000786

M. Kielman, M. Rindapaa, and C. Gaspar, Apc modulates embryonic stem-cell differentiation by controlling the dosage of ??-catenin signaling, Nature Genetics, vol.128, issue.4, pp.594-605, 2002.
DOI : 10.1038/ncb0901-793

A. Kazanjian, T. Noah, and D. Brown, Atonal Homolog 1 Is Required for Growth and Differentiation Effects of Notch/??-Secretase Inhibitors on Normal and Cancerous Intestinal Epithelial Cells, Gastroenterology, vol.139, issue.3, pp.918-946, 2010.
DOI : 10.1053/j.gastro.2010.05.081